Clinical trials: Stroke (CVA) or TIA
Ischemic Stroke
Combining Aspirin With Ticagrelor or Clopidogrel in Large-vessel Minor Stroke or TIA
Along with the current clinical trial, the efficacy and safety of a 180 mg loading dose of ticagrelor administered within 24 hours of the first-ever large-vessel minor stroke or TIA compared to 300 mg clopidogrel were assessed…
- Trial name
- NCT06591338
- Testing
- Ticagrelor 90 MG, Clopidogrel, Aspirin 75 Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 900 people
- Sponsor
- Kafrelsheikh University
Stroke, Transient Ischemic Attack
Smartwatch-Guided Secondary Prevention After Stroke
After a first stroke or transient ischemic attack (TIA), the risk of recurrence is high in the weeks and months following the initial event.
- Trial name
- WATCH-STEP (NCT07640360)
- Testing
- Smartwatch-Guided Secondary Prevention after Stroke
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Brest
Ischemic Stroke, Transient Ischemic Attack (TIA)
Effect of the Intelligent Lipid Management Decision-support System on 1-year LDL-C Target Achievement in Ischemic Stroke or TIA Patients Under Evolocumab Treatment in China
This study will conduct a cluster randomized controlled trial to Evaluate whether the Intelligent Lipid Management Decision-support System can increase the proportion of patients 1-year target achievement (<1.8 mmol/L) in acute…
- Trial name
- NCT07143149
- Testing
- the Intelligent Lipid Management Decision-support System
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Beijing Tiantan Hospital
Diabetes Mellitus, Type 2, Stroke (CVA) or Transient Ischemic Attack
Effects of Semaglutide on Intracranial Blood Flow and Brain-Barrier Permeability in Type-2 Diabetes
A human subjects research study, the primary purpose of which is to assess the EFFECTS OF SEMAGLUTIDE ON INTRACRANIAL BLOOD FLOW AND BLOOD-BRAIN BARRIER PERMEABILITY IN TYPE-2 DIABETES (T2D) through testing of the intervention on…
- Trial name
- NCT05780905
- Testing
- Semaglutide Auto-Injector
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Washington
Ischemic Stroke, TIA
Atrial Fibrillation Screening Post Ischemic Cerebrovascular Events
Stroke is one of the leading causes behind death and permanent disability in adults. Atrial fibrillation (AF) is the most common clinical arrhythmia and its prevalence is steeply increasing with age.
- Trial name
- AF-SPICE (NCT05134454)
- Testing
- Extended ECG investigation
- Where
- Sweden
- Volunteers
- 3,300 people
- Sponsor
- Karolinska Institutet
Atrial Fibrillation, Stroke, Ischemic
Echocardiographic Predictors of Atrial Fibrillation
This prospective study aims to identify the diagnostic accuracy of echocardiographic predictors of atrial fibrillation in patients with ESUS (embolic stroke of undetermined source) or TIA (transient ischemic attack).
- Conditions
- Atrial Fibrillation, Stroke, Ischemic, Embolic Stroke of Undetermined Source, TIA, Brain
- Trial name
- EPAF-7 (NCT05044208)
- Testing
- ECG monitoring
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Karl Landsteiner University of Health Sciences
Intracranial Arteriosclerosis, Stroke (CVA) or TIA
Evaluating the Safety and Efficacy of the Maurora® DES in ICAS
The purpose of the RCT trial is to evaluate whether implantation of drug-eluting stent (DES) is more efficacious than bare metal stent (BMS) in prevention of in-stent restenosis (ISR) and improvement of outcomes for symptomatic…
- Trial name
- Maurora ICAS (NCT05719883)
- Testing
- Maurora® Sirolimus Eluting Stent System, APOLLO™ Intracranial Stent System
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Beijing Tiantan Hospital
Ischemia Stroke, TIA (Transient Ischemic Attack)
Upfront Lipid-Lowering Therapy With Statins Combined With Hybutimibe in Patients With Acute Ischemic Stroke or Transient Ischemic Attack.
This study aims to evaluate whether an upfront combination lipid-lowering therapy (statins combined with hybutimibe) can further improve the 8-week LDL-C target achievement rate (<1.8 mmol/L and ≥50% reduction from baseline)…
- Trial name
- NCT07908875
- Testing
- Atorvastatin, Hybutimibe 10mg QD
- Volunteers
- 520 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Prevention of Ischemic Stroke, Acute Non-cardioembolic Ischemic Stroke
A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke
Researchers are looking for a better way to prevent an ischemic stroke which occurs when a blood clot travelled to the brain in people who within the last 72 hours had: an acute stroke due to a blood clot that formed outside the…
- Conditions
- Prevention of Ischemic Stroke, Acute Non-cardioembolic Ischemic Stroke, High-risk Transient Ischemic Attack
- Trial name
- OCEANIC-STROKE (NCT05686070)
- Testing
- Asundexian (BAY2433334)
- Where
- 741 sites in United States, Argentina and 35 more
- Volunteers
- 12,327 people
- Sponsor
- Bayer
Stroke, Ischemic Attack, Transient
Performing a Low-dose, Whole-body Angiography as the First Element of an Imaging Assessment Following Stroke / TIA
The main objective of this study is to compare two post-stroke/TIA (transient ischemic attack) imaging strategies in terms of the number of clinically important (i.e.
- Trial name
- VASCU (NCT02662751)
- Testing
- Routine Imaging Assessment, LDWBA first (CT scan)
- Where
- 2 sites in France
- Volunteers
- 260 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Transient Ischemic Attack, Non-disabling Stroke
Program of Rehabilitative Exercise and Education to Avert Vascular Events After Non-disabling Stroke or Transient Ischemic Attack: A Multi-site RCT
The objective of the Program of Rehabilitative Exercise and Education to avert Vascular Events after Non-disabling stroke and Transient ischemic attack (PREVENT) Trial is to determine whether the timely delivery of secondary…
- Trial name
- PREVENT (NCT00885456)
- Testing
- PREVENT program, Usual Care
- Where
- 2 sites in Canada
- Volunteers
- 187 people
- Sponsor
- Marilyn MacKay-Lyons
Stroke, Transient Ischemic Attack
The PREVENTS Trial: The Preventing Recurrent Events in Veterans Navigating Transient Ischemic Attack (TIA) or Stroke Trial
National recommendations state that patients with a history of transient ischemic attack (TIA) or ischemic stroke should receive hypertension treatment, including antihypertensive medication and lifestyle modification, with a…
- Trial name
- PREVENTS (NCT01020851)
- Testing
- tailored intervention
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Narrows Institute for Biomedical Research
Ischemic Stroke, Transient Ischemic Attack
Lovaza's Effect on Clopidogrel in a Neuro Population
In patients who have suffered an ischemic stroke or TIA (mini-stroke), as well as in patients who are candidates for neuroendovascular stenting, it is standard of care to treat these patients with antiplatelet therapy, or…
- Trial name
- NCT01526824
- Testing
- omega-3 polyunsaturated fatty acids (Lovaza)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Millard Fillmore Gates Hospital
Non-valvular Atrial Fibrillation
Safety and Effectiveness of Apixaban Compared to Warfarin in Secondary Prevention in Patients With Atrial Fibrillation
The purpose of this study are 1) to characterize the primary and secondary prevention patients, 2) to calculate incidence rates of stroke/SE or major bleeding in each cohort and 3) to investigate for Japanese secondary prevention…
- Trial name
- NCT05321810
- Testing
- Apixaban, Warfarin
- Where
- Japan
- Volunteers
- 193,565 people
- Sponsor
- Pfizer
Stroke (CVA) or Transient Ischemic Attack
Predictive Value of Witness-derived Secondary Cincinnati Prehospital Stroke Scale Scores in Suspected Stroke
The Cincinnati Prehospital Stroke Scale (CPSS) is traditionally scored directly by a healthcare professional or a layperson who independently observes facial droop, arm weakness, and speech disturbance, constituting the primary…
- Trial name
- NCT07277790
- Where
- Turkey (Türkiye)
- Volunteers
- 235 people
- Sponsor
- Ankara City Hospital Bilkent
Ischemic Stroke
Combining Aspirin With Cilostazol or Clopidogrel in Minor Stroke or TIA
Along with the current clinical trial, the efficacy and safety of a 300 mg loading dose of clopidogrel administered within 24 hours of the first-ever minor stroke or TIA compared to 200 mg cilostazol were assessed through NIHSS…
- Trial name
- NCT06591299
- Testing
- Cilostazol 100 MG, Clopidogrel 75mg
- Where
- Egypt
- Volunteers
- 870 people
- Sponsor
- Kafrelsheikh University
Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction
Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation
Narrowing of the carotid artery due to atherosclerosis with an unstable plaque can cause a stroke. Patients with carotid artery disease who have had a TIA or minor stroke and are at high risk of another stroke are often treated…
- Conditions
- Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction, Stroke Ischemic, Atheroscleroses
- Trial name
- IMPROVE (NCT07556887)
- Testing
- IMPROVE Risk Model
- Where
- 10 sites in Netherlands
- Volunteers
- 613 people
- Sponsor
- Maastricht University Medical Center
Ischemic Stroke, Transient Ischemic Attack
Ticagrelor Based De-Escalation of Dual Antiplatelet Therapy in Ischemic Stroke
This is a randomized, controlled, outcome assessor blind, parallel group design pilot study on 100 patient with diagnosis of ischemic stroke admitted in Bou-Ali Sina Hospital, Sari,Iran.The aim of study is to compare the efficacy…
- Trial name
- DEDAPT-TICA (NCT06653348)
- Testing
- Ticagrelor 60 + Aspirin, Ticagrelor 90 + aspirin
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mazandaran University of Medical Sciences
Stroke (CVA) or Transient Ischemic Attack, Stroke (CVA) or TIA
Trunk Impairment Scale - Adaptation and Validation in French
The objective of this project is to verify the validity and determine the clinimetric properties after translation and adaptation into French of the Trunk Impairment Scale (TIS), a scale for measuring trunk control and seated…
- Trial name
- KER-TIS fr (NCT07419087)
- Testing
- Evaluation by the TIS
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape
Patent Foramen Ovale, Stroke
Evaluation of the STARFlex® Septal Closure System in Patients With a Stroke or TIA Due to the Possible Passage of a Clot of Unknown Origin Through a Patent Foramen Ovale (PFO)
The primary objective of the study is to determine whether the STARFlex® septal closure system will safely and effectively prevent a recurrent embolic stroke/transient ischemic attack (TIA) and mortality in patients with a PFO…
- Conditions
- Patent Foramen Ovale, Stroke, Ischemic Attack, Transient
- Trial name
- NCT00201461
- Testing
- STARFlex septal closure system, Best medical therapy
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- NMT Medical