Clinical trials: Stroke (CVA) or Transient Ischemic Attack
Stroke, Ischemic Attack, Transient
Home Blood Pressure Monitoring Trial
Design: Community based randomised trial with follow up after 12 months Participants: 360 patients admitted with stroke or TIA within the past 9 months will be recruited from the wards or outpatients and randomly allocated into…
- Trial name
- NCT00514800
- Testing
- Intervention - a validated home BP monitor and support from the specialist nurse, Control - usual care (BP monitoring by their practice)
- Where
- 3 sites in United Kingdom
- Volunteers
- 360 people
- Sponsor
- St George's, University of London
Stroke (CVA) or Transient Ischemic Attack
Predictive Value of Witness-derived Secondary Cincinnati Prehospital Stroke Scale Scores in Suspected Stroke
The Cincinnati Prehospital Stroke Scale (CPSS) is traditionally scored directly by a healthcare professional or a layperson who independently observes facial droop, arm weakness, and speech disturbance, constituting the primary…
- Trial name
- NCT07277790
- Where
- Turkey (Türkiye)
- Volunteers
- 235 people
- Sponsor
- Ankara City Hospital Bilkent
Minor Stroke, Non-disabling Stroke
Stroke School -Including Physical Exercise, Patient Education and Individual Follow-up Sessions
In a randomized controlled trial the effect of 12 weeks of cross-sectorial physical exercise combined with patient education and individual follow-up session is investigated in patients with minor stroke or non-disabling stroke.
- Conditions
- Minor Stroke, Non-disabling Stroke, Transient Ischemic Attack
- Trial name
- NCT04945174
- Testing
- Cardiorespiratory exercise combined with patient education and individual follow-up sessions
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev Hospital
Brain Infarction, Transient Ischemic Attack
Aortic Arch Related Cerebral Hazard Trial (ARCH)
The ARCH is a controlled trial with a sequential design and with a prospective, randomized, open-label, blinded-endpoint (PROBE) methodology.
- Conditions
- Brain Infarction, Transient Ischemic Attack, Embolism
- Trial name
- ARCH (NCT00235248)
- Testing
- Warfarin, Clopidogrel-aspirin
- Where
- 2 sites in Australia, France
- Volunteers
- 350 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ischemic Stroke, Transient Ischemic Attack
StAtins in Frail OldEr Patients with Ischemic Stroke or Transient Ischemic Attack - the Randomized Controlled Trial
Two Dutch guidelines (Stroke and Cardiovascular Risk Management) provide conflicting advice on optimal statin treatment in older patients.
- Trial name
- SAFEST - RCT (NCT06785727)
- Testing
- Statin (atorvastatin, fluvastatin, pravastatin, rosuvastatin or simvastatin)
- Volunteers
- 612 people
- Sponsor
- Prof. dr. Nathalie van der Velde
Ischemic White Matter Disease, Transient Ischemic Attack
Cognitive Changes and Rehabilitation in People With Transient Ischemic Attack, Stroke, or Stroke Risk Factors
Stroke is a leading cause of disability; most strokes (80%) are subcortical, with ischemic damage due to occlusion in penetrating arteries.
- Conditions
- Ischemic White Matter Disease, Transient Ischemic Attack, Mild Stroke, Stroke Risk
- Trial name
- NCT01951612
- Testing
- Executive Function Training Program, Psychoeducational Training Program
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Baycrest
Coronary Artery Disease, Cerebral Stroke
Mechanistic Study of Bleeding Risk in Coronary Patients With Cerebrovascular Disease
Background: About 5% of patients with acute coronary syndrome (ACS) have had previously ischemic stroke (IS) or transitory ischemic attack (TIA).
- Conditions
- Coronary Artery Disease, Cerebral Stroke, TIA (Transient Ischemic Attack)
- Trial name
- NCT02316119
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- University of Sao Paulo General Hospital
Cerebrovascular Accident, Cerebrovascular Accident, Acute
Comparison of the Efficacy of Ticagrelor Combined With ASA to ASA Alone in Patients With Stroke
Cerebrovascular disease is the main cause of death and severe long-term disability worldwide. Antiplatelet drugs are the main drugs for ischemic stroke and TIA.
- Trial name
- NCT04962451
- Testing
- ticagrelor + ASA
- Where
- China
- Volunteers
- 13,000 people
- Sponsor
- Peking University Third Hospital
Non-valvular Atrial Fibrillation
Safety and Effectiveness of Apixaban Compared to Warfarin in Secondary Prevention in Patients With Atrial Fibrillation
The purpose of this study are 1) to characterize the primary and secondary prevention patients, 2) to calculate incidence rates of stroke/SE or major bleeding in each cohort and 3) to investigate for Japanese secondary prevention…
- Trial name
- NCT05321810
- Testing
- Apixaban, Warfarin
- Where
- Japan
- Volunteers
- 193,565 people
- Sponsor
- Pfizer
Hypertension, Ischemic Stroke
Fimasartan Blood Pressure Lowering After Acute Stroke
This study evaluates the effectiveness of fimasartan-based antihypertensive treatment and prognosis in post-acute phase of ischemic stroke or transient ischemic attack patients.
- Conditions
- Hypertension, Ischemic Stroke, Transient Ischemic Attack
- Trial name
- FABULOUS (NCT03231293)
- Where
- 27 sites in South Korea
- Volunteers
- 1,035 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Stroke, Transient Ischemic Attack (TIA)
Targeted Management Intervention for African-American Men With TIA or Stroke
Stroke is the leading cause of disability, third leading cause of death, and one of the most resource-intensive diseases among Americans.
- Trial name
- TEAM (NCT01807793)
- Testing
- Psychoeducation
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Case Western Reserve University
Acute Stroke, TIA (Transient Ischemic Attack)
Sms-guided Training After Acute Stroke or Transient Ischemic Attack - a Randomized Controlled Trial
Eighty community-living individuals in Uppsala municipality will be included. Intervention: Outdoor walking exercise program and one strength exercise. Methods: Clinical assessments, questionnaires and medical records.
- Trial name
- SMS/TIA (NCT02902367)
- Testing
- Outdoor walking and strength exercise, control group
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Uppsala County Council, Sweden
Stroke
Effectiveness of Self-monitoring and Treatment of Blood Pressure Following Stroke or Transient Ischaemic Attack
This blinded end point RCT will recruit high risk TIA and mild stroke patients (through the emergency TIA clinics and the acute stroke services at the Norfolk \& Norwich University Hospital) who require anti-hypertensive therapy…
- Trial name
- TEST-BP (NCT02947490)
- Testing
- Self BP measurement, Standard Care, Standard BP management
- Where
- United Kingdom
- Volunteers
- 165 people
- Sponsor
- University of East Anglia
Stroke, Brain Ischemia
A Novel Rural Integrated Care and Early Prevention Model for Older Adults at High Risk of or Living With Stroke in China
This cluster randomized controlled trial aims to evaluate the effectiveness of a novel telemedicine-enabled integrated care model led by rural doctors in reducing cardiovascular and cerebrovascular events among elderly adults…
- Conditions
- Stroke, Brain Ischemia, Cerebral Hemorrhage, Transient Ischemic Attack
- Trial name
- NCT07628283
- Testing
- Enhanced Usual Stroke Care, Digital Health Platform-Supported Integrated Stroke Management
- Where
- 2 sites in China
- Volunteers
- 2,510 people
- Sponsor
- Jiangsu Province (Suqian) Hospital
Stroke (CVA) or TIA, Stroke Recurrence
NORA-HOME: An Ambulatory Multimodal Monitoring Model In Patients With Minor Stroke And Transient Ischemic Attacks
In this project, we aim to validate a Home Hospitalization plan for patients with TIA or minor stroke. Our hypothesis is that our Multimodal Home Hospitalization program (NORAHOME) for patients with TIA and minor stroke is safe…
- Trial name
- NORAHOME (NCT07500116)
- Testing
- Home hospitalization
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Atrial Fibrillation
7-day Holter Monitoring in Adult Patients With Recent IS or TIA, to Measure the Prevalence of Paroxysmal Atrial Fibrillation Including Episodes Less Than 30 Seconds: Transversal Study
The main outcome of this study will be to compare the prevalence of PA AF episodes longer than 30 seconds versus the prevalence of PA AF episodes including episodes shorter than 30 seconds, in adult patients who survived IS or…
- Trial name
- MY-ATRIA (NCT04963647)
- Testing
- Adult subjects diagnosed with IS or TIA
- Where
- Italy
- Volunteers
- 660 people
- Sponsor
- Azienda Usl di Bologna
Stroke, Transient Ischemic Attack
Mobile Health to Promote Physical Activity Post Stroke
Support for physical activity is necessary to sustain health and reduce the risk of stroke recurrence after stroke or transient ischemic attack (TIA).
- Trial name
- ENAbLE-Swe (NCT05111951)
- Testing
- Mobile health-delivered physical exercise and support for physical activity, Mobile health-delivered behavior change techniques.
- Where
- Sweden
- Volunteers
- 116 people
- Sponsor
- Karolinska Institutet
Patent Foramen Ovale
Paradigm I Clinical Trial: Study of the PFX Closure System in Subjects With Cryptogenic Stroke, Transient Ischemia Attack or Paradoxical Embolism
The primary objective of this study is to demonstrate the safety of the PFX Closure System when utilized for patients with patent foramen ovale (PFO) suffering from cryptogenic stroke, transient ischemic attacks or paradoxical…
- Trial name
- NCT00196027
- Testing
- PFX Closure System
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cierra
PFO, Stroke
PFx Closure System in Subjects With Cryptogenic Stroke, TIA, Migraine or Decompression Illness
The primary object of this study is to demonstrate the continued safety and performance of the PFx Closure System when utilized for patients with PFOs suffering from cryptogenic stroke, transient ischemic attack, migraine or…
- Conditions
- PFO, Stroke, Transient Ischemic Attack, Migraine
- Trial name
- Paradigm IV (NCT00529945)
- Testing
- PFx Closure System
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Cierra
Acute Ischemic Stroke, Transient Ischemic Attack (TIA)
A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel
The purpose of this clinical study is to determine whether the addition of an oral Factor XIa Inhibitor to Aspirin and Clopidogrel is more effective than standard therapy in secondary stroke prevention.
- Trial name
- AXIOMATIC-SSP (NCT03766581)
- Testing
- BMS-986177, Clopidogrel, Aspirin
- Where
- 424 sites in United States, Argentina and 27 more
- Volunteers
- 2,366 people
- Sponsor
- Bristol-Myers Squibb