Clinical trials: Stroke Assessment
Stroke
A Study of Post-Stroke Pain and Fatigue: Clinical Evaluation and Treatment Effect
The investigators anticipate this research will shed light on metric properties of outcome measures of pain and fatigue and the effects of the combined therapy for stroke patients.
- Trial name
- NCT01913509
- Testing
- Combined Therapy of FES and BAT, Conventional Rehabilitation
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Chang Gung University
Stroke Sequelae
Balance Systems Protocol for Subacute Phase Stroke Patients.
The aim of the study is to evaluate if the application of a protocol focused on the equilibrium systems versus the conventional treatments decreases the time to acquire equilibrium in standing, the risk of falls and favors the…
- Trial name
- BSPStroke (NCT03406026)
- Testing
- Balance System Protocol Stroke, Control Stroke
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Universitat Internacional de Catalunya
Atherosclerosis Cerebral, Carotid Plaque
RESCUE: PCSK9 Inhibitors for Carotid Vulnerable Plaque Remodeling
Carotid artery stenosis is a major cause of ischemic stroke. However, many strokes occur in patients with only mild-to-moderate stenosis.
- Conditions
- Atherosclerosis Cerebral, Carotid Plaque, Vulnerable Plaque, Carotid Stenosis
- Trial name
- RESCUE (NCT07819643)
- Testing
- Intervention 1, Intervention 3, Intervention 2
- Volunteers
- 120 people
- Sponsor
- Keqiang Zhao
Cardiovascular Diseases, Surgery
Pressure Recording Analytical Method Parameters and Their Relationship With Hypotension in Hypertensive Patients
Perioperative anesthesiologists can benefit from easily obtainable hemodynamic variables detecting or quantifying the lack of an adequate compensatory capacity of the cardiovascular system in order to optimize patient management…
- Conditions
- Cardiovascular Diseases, Surgery, Hypotension, Hypotension on Induction
- Trial name
- PRAM-in-HYPO (NCT05960604)
- Testing
- Passive leg raising
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 660 people
- Sponsor
- Recep Tayyip Erdogan University
Stroke
Adherence in Upper Extremity Home-based Rehabilitation
The objective of the proposal is to determine the feasibility of implementing Ecological Momentary Assessment (EMA) and Motivational Interviewing (MI) methods to enhance adherence for a 4-week self-initiated arm training…
- Trial name
- NCT05032638
- Testing
- Therapist guided training, Upper extremity (UE) Training
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Carotid Artery Stenosis, Endarterectomy, Carotid
CAROTID ENDATORECTOMY AND GENERAL ANESTHESIA: Assessment and Evaluation of Cerebral Ischemic Damage With Clinical, Laboratory and Imaging Parameters
This study is aiming to provide us with information about the neuroprotective effect of two commonly used anesthetic drugs, during carotid endarterectomy.
- Conditions
- Carotid Artery Stenosis, Endarterectomy, Carotid, Ischemic Cerebrovascular Accident
- Trial name
- NCT07602400
- Testing
- MRI, Propofol (Astra-Zeneca), biomarkers
- Volunteers
- 160 people
- Sponsor
- University Hospital of Patras
Spasticity
ETREAT Study on Effectiveness of Botulinum Toxin Type A Injections to Treat Post-stroke Upper and/or Lower Limb Spasticity
The objective of this study is to evaluate the effectiveness of BoNT-A on functional improvement in patients with post-stroke upper and/or lower limb spasticity in the early stage of spasticity development, according to routine…
- Trial name
- ETREAT (NCT02275312)
- Where
- 17 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Ipsen
Upper Limb Spasticity
Efficacy and Safety of DaxibotulinumtoxinA for Injection for the Treatment of Adult Upper Limb Spasticity
This is a randomized, Double-Blind, Placebo-Controlled, Parallel Group, Dose-Ranging, trial to Evaluate the Efficacy and Safety of DaxibotulinumtoxinA for Injection for the Treatment of Upper Limb Spasticity in Adults After…
- Trial name
- JUNIPER (NCT03821402)
- Testing
- DAXI for injection 250 U, DAXI for injection 375 U, DAXI for injection 500 U
- Where
- 26 sites in United States
- Volunteers
- 83 people
- Sponsor
- Revance Therapeutics, Inc.
Stroke
Robot Aided Rehabilitation - Multi-joint Evaluations
Sensory and motor impairments following stroke can lead to substantial disability involving the arm and hand. The investigator hypothesized that excessive local and cross-coupled stiffness, diminished individuation and…
- Trial name
- Aim1 (NCT02359812)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Renal Replacement Therapy, Renal Dialysis
A Clinical Trial of IntensiVE Dialysis
This study will assess clinical outcomes of extended weekly hours of haemodialysis (>= 24 hours per week) compared with standard hours of haemodialysis (<=18 hours/week) in people with ESKD.
- Conditions
- Renal Replacement Therapy, Renal Dialysis, End Stage Kidney Disease, End Stage Renal Disease
- Trial name
- ACTIVE (NCT00649298)
- Testing
- haemodialysis
- Where
- 40 sites in Australia, Canada and 2 more
- Volunteers
- 200 people
- Sponsor
- The George Institute
Upper Extremity Paresis
Priming With tDCS: Expanding the Window of Recovery in Chronic Stroke
Stroke often leads to long-term disability including upper extremity (UE) dysfunction even with the provision of timely rehabilitation services.
- Trial name
- NCT03964467
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of the Sciences in Philadelphia
Alzheimer Disease, Stroke
Assessment of Social-emotional Functioning in Neurological Diseases
Empathy, defined as the ability to understand others emotions, is a fundamental concept in social interactions. It is a psychological phenomenon involving various separable components : (i) the ability to feel and imagine the…
- Conditions
- Alzheimer Disease, Stroke, Parkinson's Disease, Lewy Body Dementia
- Trial name
- Emotion (NCT01339130)
- Testing
- Computerized tests and Electrophysiological measurements
- Where
- France
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Secondary Stroke
A Study to Evaluate Cenvacibart (REGN7508) for Secondary Stroke Prevention in Adult Participants
This study will test an experimental Regeneron drug called cenvacibart (REGN7508) ("study drug") compared with a placebo (a look-alike treatment with no active medicine) on top of background antiplatelet medications.
- Trial name
- ROXI-DAISEN (NCT07876492)
- Testing
- Cenvacibart
- Volunteers
- 6,106 people
- Sponsor
- Regeneron Pharmaceuticals
Right Hemisphere Stroke
Prosody Assessment After Right Hemisphere Stroke
Following a right stroke, more than half of the patients present a communication disorder. These disorders can notably concern prosody. Nevertheless, these remain relatively poorly assessed and characterized.
- Trial name
- ProsAVC (NCT05874011)
- Testing
- understanding of prosody
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac Arrest, Stroke
Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological Assessment
PANGEA is an international prospective point prevalence study to describe the epidemiology, interventions, and outcomes in children with acute critical brain disease.
- Conditions
- Cardiac Arrest, Stroke, Traumatic Brain Injury, Brain Mass
- Trial name
- PANGEA (NCT02381977)
- Testing
- No intervention
- Volunteers
- 922 people
- Sponsor
- University of Pittsburgh
Stroke
Assessment of Robotic Assistance on Gait Parameters Among Healthy Subjects and Brain Damaged Patients
The main objective of this study is to quantitatively assess the robotic assistance given by an exoskeleton on patients gait parameters. Patients will be asked to walk with- and without the exoskeleton on a treadmill.
- Trial name
- MARAT (NCT05264103)
- Testing
- Exoskeleton for gait rehabilitation (Atalante)
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Neglect, Hemispatial
Evaluation of the Efficacy of Low-Frequency Repetitive Transcranial Magnetic Stimulation on Unilateral Neglect in Patients With Subacute-Chronic Phase After Ischemic Stroke
The aim of this study was to randomize stroke patients with unilateral neglect into 2 groups, active and sham groups, and to examine the effects of active inhibitory repetitive transcranial magnetic stimulation on the reduction…
- Trial name
- NCT06223451
- Testing
- Active Repetitive Transcranial Magnetic Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Ankara City Hospital Bilkent
Spasticity, Spastic Foot
Neuro-orthopaedic Surgery in the Treatment of the Spastic Equinovarus Foot
Spastic equinovarus foot (SEF) is a major cause of disability in stroke patients. Treatments may include physical therapy, orthosis, botulinum toxin (BTX) injections, selective tibial neurotomy and tendon lengthening and/or…
- Conditions
- Spasticity, Spastic Foot, Stroke
- Trial name
- NCT01265238
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- University Hospital of Mont-Godinne
Atrial Fibrillation/Flutter in Patients With High Risk of Stroke
A Clinical Trial to Evaluate the Detection of Atrial Fibrillation for an One Day Versus More Than or Equal to Eight Days Using MEMO Patch PLUS in Individuals Aged ≥ 75 Years, or Those at High Risk of Stroke
The purpose of this study is to evaluate the benefits in the atrial fibrillation detection rate of the continuous ECG monitoring group for more than 8 days by contrasting with one-day ECG monitoring using MEMO Patch PLUS in 1000…
- Trial name
- MEMO-DAF8 (NCT05355948)
- Testing
- MEMO Patch PLUS for 1 day, MEMO Patch PLUS for More than 8-days
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Yonsei University
Sarcopenia, Stroke
Evaluation of Sarcopenia in Patients With Stroke
The aim of this study is to investigate the prevalence of sarcopenia in stroke patients; to determine the relationship between sarcopenia and duration of stroke, age, gender, etiology of stroke, ambulation status, spasticity…
- Trial name
- NCT04387747
- Testing
- SARCOPENIA IN STROKE PATIENTS
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
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