Clinical trials: Stroke Assessment
Tetraplegia, Locked-in Syndrome
Investigation on the Cortical Communication (CortiCom) System
The CortiCom system consists of 510(k)-cleared components: platinum PMT subdural cortical electrode grids, a Blackrock Microsystems patient pedestal, and an external NeuroPort Neural Signal Processor.
- Conditions
- Tetraplegia, Locked-in Syndrome, Brainstem Stroke, Amyotrophic Lateral Sclerosis
- Trial name
- CortiCom (NCT03567213)
- Testing
- Surgical implantation of CortiCom system
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Johns Hopkins University
Stroke, Acute
Stroke Treatment With Acute Reperfusion and Simvastatin
The purpose of this study is to determine whether simvastatin treatment started within the first 12 hours from stroke onset improves neurological and functional outcomes, evaluated at seventh day/discharge or at the third month.
- Trial name
- NCT01073007
- Testing
- Simvastatin
- Where
- 20 sites in Spain
- Volunteers
- 104 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Stroke
Bimanual Robotic Exoskeletal Platform for the Treatment of the Upper Limb in Patients With Stroke. A Feasibility Study
The purpose of the study is to test the technical functionality, safety, and feasibility of a bimanual robotic exoskeletal platform and associated serious games in order to offer information on technological and functional…
- Trial name
- Birehab (NCT05176600)
- Testing
- Robotic rehabilitation using the Arm Light Exoskeleton Rehab Station (ALEx RS) and bimanual serious games, Robotic rehabilitation using the Arm Light Exoskeleton Rehab Station (ALEx RS) and unimanual serious games
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Wearable Robotics srl.
Intracranial Atherosclerotic Disease (ICAD), Intracranial Arterial Stenosis
Photon-counting CT for Intracranial Stent Assessment
Intracranial atherosclerotic disease is an important cause of ischemic stroke, and intracranial stent implantation is increasingly used for patients with severe stenotic lesions.
- Conditions
- Intracranial Atherosclerotic Disease (ICAD), Intracranial Arterial Stenosis, Stent Restenosis, Ischemic Stroke
- Trial name
- NCT07769814
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xin Lou
Dysarthria As Late Effect of Stroke
The Efficacy and Feasibility of Smartphone-Based Speech Therapy for People with Post-Stroke Dysarthria
This clinical trial aims to determine if a new smartphone-based speech therapy is effective and feasible for patients with post-stroke dysarthria.
- Trial name
- NCT05865106
- Testing
- Smartphone-based speech therapy, Traditional speech therapy
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Ewha Womans University Seoul Hospital
Acute Ischemic Stroke
Evaluate the Efficacy and Safety of TTYP01 Tablets in the Treatment of Acute Ischemic Stroke
The study is designed as a multi-center, randomized, double-blind, parallel, placebo-controlled trial to evaluate the efficacy and safety of TTYP01 tablets in the treatment of acute ischemic stroke.
- Trial name
- NCT06648304
- Testing
- TTYP01 tablets
- Where
- China
- Volunteers
- 614 people
- Sponsor
- Shanghai Auzone Biological Technology Co., Ltd.
Hemiplegia, Hemiparesis
Evaluation of the Safety and Performance of the AWAKE Device in Patients With Hemiplegia or Hemiparesis Secondary to Stroke (ACV).
Stroke is a leading cause of disability in adults, with gait impairment being a key functional limitation. Although lower limb exoskeletons are used in rehabilitation, the available evidence focuses on bilateral devices used in…
- Trial name
- VAWAKE (NCT07867847)
- Testing
- Bionic System (AWAKE)
- Volunteers
- 20 people
- Sponsor
- Bionic Mobility Solutions, S.L.
Stroke, Acute
A Study to Evaluate the DAISe System During Neurointervention for Acute Ischemic Stroke
This purpose study is to demonstrate the safety and performance of the DAISe System used to remove clot in the brain during a stroke.
- Trial name
- NCT03957278
- Testing
- DAISe System
- Where
- 2 sites in Belgium
- Volunteers
- 4 people
- Sponsor
- MIVI Neuroscience, Inc.
Stroke, Acute, Dysphagia
Impact of Physical Therapy of Dysphagia on Preventing Pneumonia in Acute Stroke Patients
To investigate the impact of physical therapy intervention of dysphagia on preventing pneumonia in acute stroke patients
- Conditions
- Stroke, Acute, Dysphagia, Pneumonia
- Trial name
- NCT06010940
- Testing
- Dietary supplement, Physical therapy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Ischemic Stroke, Transient Ischemic Attack
Chinese Atherosclerosis Risk Evaluation- Phase II
Stroke is the first and the fourth leading cause of death in the United States and China, respectively. Disruption of cerebrovascular vulnerable atherosclerotic plaque is the major etiology of ischemic stroke.
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Carotid Atherosclerotic Disease
- Trial name
- CARE-II (NCT02017756)
- Where
- 14 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Tsinghua University
Cerebrovascular Stroke, Body Composition
Assessment of Body Composition, Fatigue, Mobility and Functional Status in Post-Stroke Individuals
The goal of this randomized controlled trial is to evaluate body composition, fatigue, mobility level, functional status in with stroke individuals.
- Trial name
- NCT06255145
- Testing
- Bioelectrical Impedance Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Stroke
Effects of Whole Body Vibration in Subacute Stroke Patients
The overall aim of the proposed study is to determine whether whole body vibration is beneficial in promoting bone turnover, physical fitness and neuromotor performance in patients with subacute stroke.
- Trial name
- NCT00796237
- Testing
- Whole body vibration therapy, standing on the vibration platform but no vibration will be applied
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Acute Ischemic Stroke
Single Arm Trial to Evaluate the Safety and Effectiveness of the Route 92 Medical Reperfusion System
The objective of the study is to evaluate the safety and effectiveness of the Route 92 Medical Monopoint Reperfusion System with the Hi Point 88 and HiPoint 70 Reperfusion Catheters when used to aspirate emboli in acute ischemic…
- Trial name
- SUMMITNZ (NCT05429658)
- Testing
- Thrombectomy
- Where
- 2 sites in New Zealand
- Volunteers
- 66 people
- Sponsor
- Route 92 Medical, Inc.
Ischemic Stroke
Evidence-based Evaluation of TCM Key Syndrome Differentiation and Treatment for Acute Ischemic Stroke
The main purpose of this trial is to determine whether Chinese medicine (CM) for eliminating phlegm and clearing heat (EPACH) recipe continuously with nourishing Qi and activating blood circulation (NQABC) recipe, oral within 72…
- Trial name
- NCT04199455
- Testing
- Integrative Treatment (EPACH Recipe Granules + NQABC Recipe Granules)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Neurological Rehabilitation, Stroke
Evaluation of Hand Strength and Spasticity in Hemiplegic Patients
The aim in this study is to evaluate spasticity and hand grip strength with a finger hand robot in the Turkish population.
- Conditions
- Neurological Rehabilitation, Stroke, Upper Extremity Problem
- Trial name
- NCT05662878
- Testing
- Assessment of Hand Strength and Spasticity
- Where
- Turkey (Türkiye)
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Cognitive Impairment
RIVastigmine In Vascular cognitivE Impairment
The study is a 24-week prospective, double blind, randomized, placebo-controlled pilot study of 9 mg / day Rivastigmine in patients with Vascular Cognitive Impairment Not Dementia (CIND) to evaluate efficacy, safety and…
- Trial name
- RIVIVE (NCT00669344)
- Testing
- Exelon (rivastigmine)
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Stroke
Pilot RCT of Computer-based Eye Movement Training
The goal of this study is to learn whether NeuroEyeCoach, a computer-based eye movement training programme, can help stroke survivors with visual field loss. The study will also assess whether a larger clinical trial is feasible.
- Trial name
- CRYSTAL (NCT07752563)
- Testing
- NeuroEyeCoach eye movement training, Usual Care
- Volunteers
- 60 people
- Sponsor
- Glasgow Caledonian University
Ischemic Stroke
Risk Assessment Model for Ischemic Stroke Endpoint Events
The present study aims to develope a risk assessment model of ischemic stroke endpoint events combining multi-dimensional traditional Chinese medicine(TCM) indicators with modern medicine indicators.
- Trial name
- NCT03174535
- Testing
- Qilong capsules (QLC), produced by Jining Huaneng Pharmaceutical Factory Co., Ltd.
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Acute Ischemic Stroke
Real-World Evaluation of Recombinant Human Prourokinase for Acute Ischemic Stroke Within 4.5 Hours
Acute ischemic stroke is a major cause of disability and death. Intravenous thrombolytic therapy is an important treatment option when given within the appropriate time window.
- Trial name
- PRISM (NCT07787325)
- Testing
- Recombinant Human Prourokinase
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Acute Stroke
Evaluation of Neurosteer System in Stroke Patients
This is an observational study. Patients who fulfill all inclusion criteria and none of the exclusion criteria will be enrolled in the study, be neurologically evaluated and will go through a series of EEG recordings during their…
- Trial name
- NCT05524415
- Testing
- Neurosteer EEG recorder
- Where
- Israel
- Sponsor
- Neurosteer Ltd.
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