Clinical trials: Stroke Assessment
Stroke and Healthy Subjects
Paired Associative Stimulation in Post-stroke Hand Motor Deficits
Introduction The motor impairment of the upper extremity is the most common sequelae after ischemic stroke. Transcranial magnetic stimulation (TMS) is a promising non- invasive technique in the rehabilitation of motor deficits.
- Trial name
- PAS-stroke (NCT02284087)
- Testing
- PAS
- Where
- France
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
MACE, Cardiac Death
Real-World Cohort Study of Cardiopulmonary Function in Chinese Patients With Cardiovascular Disease: CPET Evaluation and Five-Year Prognostic Follow-Up Based on a Multicenter Structured Data Platform
The goal of this observational study is to observe the characteristics of cardiopulmonary exercise testing (CPET) parameters in patients across different cardiovascular diseases and to evaluate the predictive value of…
- Conditions
- MACE, Cardiac Death, Unplanned Repeat Revascularization, Cardiac Rehospitalization
- Trial name
- China-CPET (NCT07130968)
- Where
- China
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Stroke, Acute
Mobile MRI for Immediate Radiological Acute Cerebral Lesion Evaluation in Stroke
This prospective observational study will evaluate the potential value of mobile MRI in patients with suspected or proven acute stroke and Transient Ischemic Attack (TIA), undertaking additional imaging in the emergency…
- Trial name
- MIRACLES (NCT06262217)
- Testing
- Mobile MRI scanner
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- NHS Greater Glasgow and Clyde
Post-Stroke Spasticity, Cerebrovascular Accident
Study of GSK1358820 In Patients With Post-Stroke Lower Limb Spasticity
This is a study to confirm the superior efficacy of GSK1358820 over placebo in patients with equinus deformity associated with post-stroke lower limb spasticity using the Modified Ashworth Scale (MAS) ankle score.
- Trial name
- NCT00460655
- Testing
- GSK1358820
- Where
- 20 sites in Japan
- Volunteers
- 120 people
- Sponsor
- GlaxoSmithKline
Stroke, Gait Disorders, Neurologic
FeetMe® Monitor: Alternative for the Evaluation of Gait Speed After Stroke
The aim of this study is to validate a smart insoles system in comparison to the gold-standard GaitRite for a pathologic gait. The device evaluate gait parameters in real time thanks to an embedded algorithm based on the…
- Trial name
- NCT04266743
- Testing
- FeetMe Monitor
- Where
- France
- Volunteers
- 30 people
- Sponsor
- FeetMe
Dysphagia, Stroke
Dysphagia Study Using Novel Microphone Device
This study aims to collect swallowing acoustics with a novel non-invasive wearable surface microphone device during routine work-up, videofluoroscopic swallow study (VFSS), of patients with dysphagia (swallowing trouble).
- Trial name
- NCT07251140
- Testing
- Microphone device
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Endocarditis, Stroke
Evaluation of the Prognostic Impact of a Neuro-vascular Examination Associated With Cerebral MRI in the Acute Phase of Infectious Endocarditis
Infectious endocarditis (IE) is a serious condition with an annual incidence of 3 to 10 per 100,000 people. Brain infarctions complicate approximately 20-40% of endocarditis.
- Trial name
- POMPEI (NCT05378126)
- Testing
- Neurological assessment
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Hospices Civils de Lyon
Acute Stroke, Upper Limb Motor Deficit
Effect of Early Tendon Vibrations on Upper Limb Motor Recovery After a Stroke
Strokes often induce a motor deficit. The resulting immobilization is in itself an aggravation factor since it worsens the motor deficit induced by the stroke itself.
- Trial name
- VIBRASTROKE (NCT07905625)
- Testing
- TVS rehabilitation sessions
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Stroke
Physical Performance and Cognitive Functions in Patients With Chronic Stroke
This study aims to investigate the impact of cognitive impairment on upper extremity physical performance, cognitive skills, and functional independence in individuals with chronic stroke.
- Trial name
- NCT07887776
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Kutahya Health Sciences University
Stroke
PROPEL Randomized Trial
It is important for people with stroke to exercise in order to improve their overall recovery and general health. However, these individuals are less physically active than people without stroke, and they often do not achieve the…
- Trial name
- NCT02951338
- Testing
- PROPEL program, Group aerobic exercise
- Where
- 5 sites in Canada
- Volunteers
- 57 people
- Sponsor
- Toronto Rehabilitation Institute
Stroke
Robot Mediated Therapy-Feasibility Study and Preliminary Effects
The goal of this clinical trial is to investigate the feasibility of the application of robot mediated impairment-training (RMIT) and robot mediated task-specific training (RMTT) in acute stroke patients with upper limb…
- Trial name
- NCT05729633
- Testing
- Robot mediated upper limb therapy
- Volunteers
- 4 people
- Sponsor
- Changi General Hospital
Stroke
Non-invasive Neuromodulation NESA Application in the Rehabilitation of Stroke Sequelae
To evaluate whether NESA microcurrents can be used as an effective treatment for various sequelae present in stroke patients, specifically in the treatment of spasticity, balance, pain; and whether it affects quality of life…
- Trial name
- NCT05853952
- Testing
- Non-invasive Neuromodulation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Las Palmas de Gran Canaria
Stroke
rTMS and Conventional Physical Therapy After Stroke
Given previous evidence that non invasive brain stimulation enhances the effects of conventional therapies, this randomized sham-controlled trial with 4-weeks follow-up aimed to determine if the repetitive transcranial magnetic…
- Trial name
- NCT01875536
- Testing
- rTMS, conventional physical therapy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Hemispatial Neglect
The Effectiveness of Transcranial Magnetic Stimulation and Mirror Therapy in Hemispatial Neglect
The aim of this study is to evaluate the effectiveness of continuous Theta Burst Stimulation added to mirror therapy on neglect associated with stroke.
- Trial name
- NCT07228871
- Testing
- Mirror Therapy, cTBS, Cognitive rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Ankara Etlik City Hospital
Stroke
The Missing Link- Development and Feasibility Evaluation of Person-centred Transitions From the Stroke Unit to the Home
The aim is to design, implement and evaluate new person-centred transitions between stroke units and the home. The development of person-centred transition will be performed together by people with stroke, significant others…
- Trial name
- Missing Link (NCT02925871)
- Testing
- Co-designed person-centred care transitions, Current care transitions
- Where
- 2 sites in Sweden
- Volunteers
- 49 people
- Sponsor
- Karolinska Institutet
Craniectomy, Trephined Syndrome
External Post-Operative Skull Prosthesis to Prevent Sunken Flap Syndrome in Craniectomy Patients
Patients that undergo decompressive craniectomy are at risk of delayed changes in brain function known as "Sunken Flap Syndrome" or "Syndrome of the Trephined." The goal of this clinical trial is to see if placing a prosthetic…
- Conditions
- Craniectomy, Trephined Syndrome, Traumatic Brain Injury (TBI) Patients, Ischemic Stroke
- Trial name
- ExO-Skull (NCT06899711)
- Testing
- External Cranial Prosthesis
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Johns Hopkins University
Healthy
Safety,Tolerability, and Pharmacokinetic of KPCXM18 for Injection
to assess the safety,Tolerability, and pharmacokinetic of KPCXM18 for injection in healthy subjects
- Trial name
- NCT04629287
- Testing
- KPCXM18
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Kunming Pharmaceuticals, Inc.
Hemiplegic Stroke, Hemiplegic Cerebral Palsy
Evaluating Human-Machine Interfaces in a Robotic Thumb Orthosis
We plan to investigate whether the Isolated Orthosis for Thumb Actuation (IOTA) can effectively facilitate the ability of participants to perform a specific set of clinically relevant tasks conducted in a clinic setting.
- Trial name
- IOTA (NCT01973426)
- Testing
- Isolated Orthosis for Thumb Actuation (IOTA)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wyss Institute at Harvard University
Stroke
Effectiveness of a Standardized Stroke Upper Limb Rehabilitation Program with Shortened Fugl-Meyer Assessment Stratification
The objective of the study was to investigate the effectiveness of a standardized stroke upper limb rehabilitation program with stratification using Shortened Fugl-Meyer Assessment (S-FM).
- Trial name
- NCT06902948
- Testing
- upper limb function training
- Where
- Hong Kong
- Volunteers
- 44 people
- Sponsor
- Sally Hiu Lam Wong
Hemiplegia, Spastic
Evaluation of the Effect of an Ankle Foot Orthoses for Ambulatory Function
The main purpose of this investigation is to evaluate the effect of a lower leg brace on walking efficiency and community walking in people who have weakness in one side of the body caused after a stroke.
- Trial name
- NCT01336517
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation