Clinical trials: Stroke Hemorrhagic
Hemorrhagic Stroke
Precision Clinical and Genetic Tools for Brain Health in Hemorrhagic Stroke
The overall goal of this study is to increase health care provider awareness for common risk factors and comorbidities in patients with hemorrhagic stroke that are related to impaired brain health, to ultimately improve patients…
- Trial name
- NCT05643001
- Testing
- In-patient and out-patient electronic health record alert
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Massachusetts General Hospital
Acute Ischemic Stroke
Treatment of Acute Ischemic Stroke With Rt-PA Combined With Edaravone Dexborneol
In this study, a multicenter, randomized, controlled, prospective cohort study was conducted to observe the effect of Edaravone Dexborneol on the incidence and outcome of bleeding transformation after thrombolysis in acute…
- Trial name
- TASPE (NCT06248242)
- Testing
- Edaravone dexborneol
- Where
- China
- Volunteers
- 400 people
- Sponsor
- The Second Hospital of Hebei Medical University
ST Elevation Myocardial Infarction
Study of Efficacy and Safety of GNR-060 vs Metalyse in Patients With ST Elevation Myocardial Infarction
GNR-060(JSC "GENERIUM", Russia) is a proposed biosimilar to the referent product Metalyse. This study is to compare the clinical efficacy and safety of GNR-060 vs Metalyse as a thrombolitic agent in patients with with ST…
- Trial name
- NCT05601999
- Testing
- GNR-060, Metalyse
- Where
- 11 sites in Russia
- Volunteers
- 244 people
- Sponsor
- AO GENERIUM
Stroke, Hemiparesis of the Upper Limb Following Stroke
Neurophysiological and Behavioral Effects of Combining Transcranial Direct Current Stimulation (tDCS) and Modified-Constraint Induced Movement Therapy (mCIMT)
This clinical trial aims to evaluate the effect of different types of tDCS modulation with mCIMT in improving affected upper-limb motor function for stroke patients.
- Conditions
- Stroke, Hemiparesis of the Upper Limb Following Stroke, Stroke Rehabilitatiom
- Trial name
- tDCS and mCIMT (NCT06786000)
- Testing
- Anodal tDCS combined with mCIMT, Cathodal tDCS combined with mCIMT, Bihemispheric tDCS combined with mCIMT
- Where
- Saudi Arabia
- Volunteers
- 300 people
- Sponsor
- King Saud University
Stroke, Ischemic Stroke
Myosuit Chronic Stroke Protocol
A stroke is a vascular condition that can suddenly cause the loss of neurological functions. The disability derived from a stroke can imply reduced communication and limited activities of daily living in the long term.
- Conditions
- Stroke, Ischemic Stroke, Haemorrhagic Stroke
- Trial name
- MyoSCSP (NCT05579197)
- Testing
- Lower-limb robotic intervention
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Hereditary Haemorrhagic Telangiectasia, PFO - Patent Foramen Ovale
Non-Invasive Detection of Pulmonary Right-to-Left Shunts Using the SONAS Ultrasound Device
The goal of this clinical trial is to learn how well the SONAS ultrasound device can detect right-to-left shunts of adults with hereditary hemorrhagic telangiectasia (HHT) who are already scheduled for a contrast bubble…
- Conditions
- Hereditary Haemorrhagic Telangiectasia, PFO - Patent Foramen Ovale, Pulmonary Arteriovenous Malformation
- Trial name
- SONAS (NCT07414446)
- Testing
- Transcranial Ultrasound Device
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- St. Antonius Hospital
Atrial Fibrillation, Anticoagulants and Bleeding Disorders
Left Atrial Appendage Occlusion for AF Patients Unable to Use Oral Anticoagulation Therapy
Up to 5% of Atrial Fibrillation (AF) patients may have or develop contraindications to use oral anticoagulation (OAC). Randomized controlled trial (RCT) data suggest that Left Atrial Appendage Occlusion (LAAO) may provide a…
- Trial name
- COMPARE-LAAO (NCT04676880)
- Testing
- Left atrial appendage occlusion (Watchman FLX or Amplatzer Amulet)
- Where
- 14 sites in Netherlands
- Volunteers
- 609 people
- Sponsor
- R&D Cardiologie
Hemorrhagic Stroke, Venous Thromboembolism
PREvention of VENous Thromboembolism In Hemorrhagic Stroke Patients
Patients with cerebral hemorrhage (ICH) have a high risk of venous thromboembolism. Intermittent pneumatic compression combined with elastic stockings have been shown to be superior to elastic stockings alone in reducing the rate…
- Conditions
- Hemorrhagic Stroke, Venous Thromboembolism, Deep Venous Thrombosis
- Trial name
- PREVENTIHS (NCT01573169)
- Testing
- Enoxaparin, Graduated compression stockings and/or intermittent pneumatic compression and/or early mobilization
- Where
- Italy
- Volunteers
- 73 people
- Sponsor
- University Of Perugia
Antiplatelet Therapy, Hemorrhagic Infarction
Early Antiplatelet Therapy After Hemorrhagic Infarction in Acute Ischemic Stroke Treated With Intravenous Thrombolysis (HITs)
Previous study showed that the proportions of hemorrhagic Infarction after intravenous thrombolysis were 24.2% and 32.5% in the control group and the alteplase group, and most of them were asymptomatic.
- Trial name
- NCT04624295
- Testing
- Early aspirin Therapy, Non-Early aspirin Therapy
- Where
- China
- Volunteers
- 294 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Traumatic Brain Injury (TBI) Patients, Stroke Hemorrhagic
Non-invasive Intracranial Pressure Monitoring to Improve Emergency Care in Brazil's Public Health System
The goal of this observational study is to evaluate the diagnostic accuracy of non-invasive intracranial pressure (ICP) and intracranial compliance (ICC) pulse morphology and associated parameters (such as the P2/P1 ratio and…
- Conditions
- Traumatic Brain Injury (TBI) Patients, Stroke Hemorrhagic, Stroke Ischemic
- Trial name
- NCT07210333
- Testing
- non-invasive intracranial pressure monitoring
- Where
- 3 sites in Brazil
- Volunteers
- 300 people
- Sponsor
- Braincare USA Corp
Stroke
Blod Biomarkers for Stroke
The purpose of the project is to investigate specific markers in blood samples from patients with stroke (ischemic or hemorrhagic).
- Trial name
- NCT03941249
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Helle Klingenberg Iversen, MD, DmSc
Stroke, Stroke, Ischemic
Ischemic Conditioning Improves Walking Function Post Stroke
This innovative study will address scientific and clinical areas relatively unexplored in chronic stroke that could lead to greater recovery of walking.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Cardiovascular
- Trial name
- NCT04038697
- Testing
- Ischemic Conditioning, Treadmill Training
- Where
- 2 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Cerebral Vein Thrombosis
Rivaroxaban vs. Warfarin in CVT Treatment
Cerebral venous thrombosis (CVT) is an uncommon venous-type of stroke tends to affect younger patients with somewhat different risk factors and much better outcome compared to arterial strokes.
- Trial name
- RWCVT (NCT04569279)
- Testing
- Rivaroxaban, Warfarin
- Where
- Syria
- Volunteers
- 71 people
- Sponsor
- Damascus University
Ischemic Stroke, Cryptogenic, Ischemic Stroke, Embolic
Left Atrial Strain and Cryptogenic Stroke
Cryptogenic stroke is a type of stroke in which the cause of the blood clot cannot be identified, leaving many patients without a clear treatment plan and at high risk for another stroke.
- Conditions
- Ischemic Stroke, Cryptogenic, Ischemic Stroke, Embolic, Hemorrhagic Stroke, Embolic Stroke of Undetermined Source
- Trial name
- LAS-ESUS (NCT07224178)
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- University of Pittsburgh
Subarachnoid Haemorrhagic Stroke
Investigation of the Role of Inflammatory Markers in the Early Detection of Cerebral Vasospasm, Delayed Cerebral Ischemia, and Meningitis Associated With External Cerebrospinal Fluid Drainage After Non-Traumatic Subarachnoid Hemorrhage - A Prospective Case-Control Study
Background Non-traumatic subarachnoid haemorrhage (SAH) is frequently complicated by delayed cerebral ischaemia (DCI) and by ventriculitis/meningitis when external CSF drains are used; bedside TCCD has limited accuracy for…
- Trial name
- NCT07129603
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Tamas Vegh, MD
Hemorrhagic Stroke
Esmolol for the Treatment of Hypertension After Intracerebral Hemorrhage Study (ETHICHS)
Because of its pharmacokinetic characteristics, such as short half-life and its safety profile, esmolol hydrochloride is a beta blocker suitable for venous use in the form of continuous infusion.
- Trial name
- ETHICHS (NCT03743103)
- Testing
- Brevibloc, 10 Mg/mL Intravenous Solution, Nitroprusside, Sodium
- Where
- 7 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Stroke, Chronic Stroke Patients
kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot
kTMP, kilohertz transcutaneous magnetic perturbations, is a low intensity transcranial magnetic stimulation technique that will be used in this study to promote arm/hand rehabilitation in patients who have been disabled by stroke.
- Conditions
- Stroke, Chronic Stroke Patients, Arm Weakness as a Consequence of Stroke
- Trial name
- NCT07631078
- Testing
- kTMP
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Magnetic Tides
Ischaemic Stroke, Hemorrhagic Stroke
Exploratory Study on the Potential Cross-System Effects of BCI-FES Hand Therapy on Dysphagia and Aphasia in Chronic Stroke Patients
The goal of this neurorehabilitation explorative study is to investigate how a closed-loop Brain-Computer Interface Functional Electrical Stimulation (BCI-FES) therapy, used within the intended purpose for hand rehabilitation…
- Trial name
- c-STEPS (NCT06940635)
- Testing
- closed-loop BCI-FES device
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- VASCage GmbH
Stroke, Acute, Stroke, Ischemic
Non-invasive TRanscutaneous Cervical Vagus Nerve Stimulation as a Treatment for Acute Stroke; Safety and Feasibility Study
This study aims to determine safety and feasibility of non-invasive transcutaneous cervical Vagus nerve stimulation (nVNS) when delivered promptly after clinical diagnosis of acute stroke.
- Conditions
- Stroke, Acute, Stroke, Ischemic, Stroke, Stroke, Hemorrhagic
- Trial name
- TR-VENUS (NCT03733431)
- Testing
- Gammacore device
- Where
- 8 sites in Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Turkish Stroke Research and Clinical Trials Network
Stroke, Hemorrhagic Transformation Due to Acute Stroke
Astragalus Membranaceus for Brain Edema Induced by Hemorrhagic Stroke
Astragalus membranaceus (AM) is used to treat stroke for a long period, and a number of studies have known that AM can reduce cerebral infarction area and has anti-oxidation.
- Trial name
- NCT01428401
- Testing
- Chinese Herb Astragalus membranaceus
- Volunteers
- 80 people
- Sponsor
- China Medical University Hospital