Clinical trials: Stroke Patient
Cerebrovascular Stroke, Stroke, Acute
Safety and Effectiveness of SOFIA™/SOFIA™ PLUS for Direct Aspiration in Acute Ischemic Stroke
Sesame is a European, multi-center, single arm, prospective, observational registry. Sesame aims to demonstrate that use of SOFIA™/SOFIA™ PLUS catheter for direct aspiration as a first line treatment technique is fast, safe and…
- Conditions
- Cerebrovascular Stroke, Stroke, Acute, Cerebral Stroke
- Trial name
- SESAME (NCT03417349)
- Testing
- Sofia
- Where
- 15 sites in Austria, France and 3 more
- Volunteers
- 250 people
- Sponsor
- Dr. Markus Alfred Möhlenbruch
Stroke, Unilateral Spatial Neglect
Serious Game Therapy in Neglect Patients
The growing field of new technologies offers new perspectives for neurorehabilitation. Serious games are a promising solution in the rehabilitation of cognitive impairments, and they may be useful in the rehabilitation of…
- Trial name
- NCT05805748
- Testing
- serious game rehabilitation
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Hopitaux de Saint-Maurice
Stroke, Mild Cognitive Impairment
Investigating Neurocognitive, Motor and Biological Effects of MindLenses Professional in Neurological Diseases
This study aims to explore the effects of the treatment with MindLenses Professional device on cognitive and motor performances,as well as on the levels of a neurotrophic factor implied in brain plasticity, that is the brain…
- Trial name
- MindLensesN (NCT05826626)
- Testing
- MindLenses Professional, Conventional rehabilitation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Transient Ischemic Attack
Lleida TIA Intervention Study
Having a transient ischemic attack (TIA) or a minor stroke is a real risk factor not only for early recurrent stroke but also for major extracranial vascular events.
- Trial name
- LLETIS (NCT04524078)
- Testing
- intensive integrated intervention care program
- Volunteers
- 100 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Stroke
Feasibility and Safety of In-bed Self-exercise in Patients With Subacute Stroke
The goal of this to investigate the feasibility and safety of in-bed self-exercises based on EMG-sensor feedback in subacute stroke patients. The main question is feasibility and safety.
- Trial name
- NCT05820815
- Testing
- in-bed self-exercises based on EMG-sensor feedback intervention
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
Stroke
High-definition Transcranial Electrical Stimulation for Upper Extremity Rehabilitation
Upper limb hemiparesis is the most common sequelae in patients, severely impacting their independence and quality of life. Transcranial electrical stimulation (tCES) is a non-invasive and safe treatment, which uses a low direct…
- Trial name
- NCT06409143
- Testing
- HD-tES, UE rehabilitation, HD-tES (Bilateral)
- Where
- 3 sites in Taiwan
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke, Cardiovascular
The Effects of Core Stabilization Exercises With Swisball in Stroke Patients
Stroke is often associated with secondary complications such as nutritional and metabolic disorders, endocrine dysfunction, mental problems, and cardiopulmonary disorders caused by neurological and musculoskeletal deficits.
- Trial name
- NCT04777955
- Testing
- core stabilization exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul University - Cerrahpasa
Brain Injuries, Stroke
Novel Head Protection Prototype Device for Decompression Craniectomy
A proof-of-concept (POC) proposal to study the feasibility of customized head protection prototype device (HPPD) using 3D printed externally-applied moulded skin prosthesis integrated to the craniectomy bony skull defect.
- Trial name
- HPPD (NCT04021095)
- Testing
- Head protection prototype device
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Stroke, Spasticity, Muscle
Using Shear Wave Ultrasound Elastography for Follow up After Anti-spastic Intervention Among Stroke Patients
Spasticity of stroke patient, a very common complication in clinical practice, affects performance of hand function and gait pattern. It also interferes with quality of life of patients severely.
- Conditions
- Stroke, Spasticity, Muscle, Botulism, Ultrasound
- Trial name
- NCT04550793
- Testing
- Botulinum toxin injection
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Stroke, Neurologic Diseases, General
Cerebril™ in Patients With Lobar Hemorrhage Related to Cerebral Amyloid Angiopathy
The main objective of this study is to evaluate the safety, tolerability and pharmacokinetics of Cerebril™ in Cerebral Amyloid Angiopathy (CAA) patients who have had lobar cerebral hemorrhage.
- Trial name
- NCT00056238
- Testing
- NC-758 (Anti amyloidotic [Aß] agent)
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Bellus Health Inc. - a GSK company
Stroke
A Diagnosis Study of a New Prehospital Strokeidentification Test, the PreHospitalt Ambulans Stroke Test (PreHAST), to be Used to Triage Patients With Suspected Stroke
The aim of the Pre-HAST study is to improve identification and triage of patients with suspected stroke in order to get the right patient to the right level of care as fast as possible.
- Trial name
- Pre-HAST (NCT04555499)
- Testing
- Standardized neurological examination
- Where
- 2 sites in Sweden
- Volunteers
- 78 people
- Sponsor
- Karolinska Institutet
Stroke
Fear of Falling: Clinical and Psychological Determinants in Neurological Patients. A Cross-Sectional Observational Study.
Stroke survivors are at increased risk of falls and often develop Fear of Falling (FoF), which can negatively affect mobility, independence, participation in daily activities, and quality of life.
- Trial name
- NCT07698444
- Testing
- Clinical and neuropsychological evaluation
- Where
- Italy
- Volunteers
- 106 people
- Sponsor
- Universita di Verona
Hyperlipidemia, Hypercholesterolemia
Patient and Provider Assessment of Lipid Management Registry
The purpose of the Patient and Provider Assessment of Lipid Management Registry (PALM) is to gain a better understanding of physicians' cholesterol medication prescribing practices, patient and physician attitudes and beliefs…
- Conditions
- Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, Diabetes
- Trial name
- PALM (NCT02341664)
- Where
- 14 sites in United States
- Volunteers
- 7,658 people
- Sponsor
- Duke University
Acute Ischemic Stroke
Safety and Preliminary Efficacy of Allogeneic Endothelial Progenitor Cells (EPCs) in Patients With Acute Ischemic Stroke
This is a multicenter, randomized, double-blind, placebo-controlled, dose-Escalation clinical study to investigate the safety and efficacy of EPCs transplantation in Acute ischemic stroke.
- Trial name
- NCT05993884
- Testing
- iEPCs
- Where
- 2 sites in China
- Volunteers
- 27 people
- Sponsor
- Allife Medical Science and Technology Co., Ltd.
Cognitive Decline, Dementia, Vascular
Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients
To test the effects of a 2- to 3-year intervention of the MIND diet versus usual post-stroke care on cognitive decline, the characteristic feature of dementia, and on brain biomarkers of Alzheimer's Disease (AD) and vascular…
- Conditions
- Cognitive Decline, Dementia, Vascular, Alzheimer Disease, Dementia
- Trial name
- NCT04337255
- Testing
- Behavioral Dietary intervention ( MIND Diet), Behavioral Usual Care Diet Intervention
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- Rush University Medical Center
Acute Ischemia
REperfusion With P2Y12 Inhibitors in Addition to mEchanical thRombectomy for perFUsion Imaging Selected Acute Stroke patiEnts
The main objective is to evaluate the efficacy of IV administration of the P2Y12 inhibitor (cangrelor) in addition to mecanich thrombectomy and WMD versus mecanich thrombectomy and WMD alone on the functional prognosis at 3…
- Trial name
- REPERFUSE (NCT04667078)
- Testing
- Cangrelor, best medical management
- Where
- 13 sites in France
- Volunteers
- 368 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Stroke, Acute Stroke
Effectiveness of Best Care Practices in Acute Stroke in Conventional Hospitalization (BEST CARE ICTUS_HC)
The goal of this clinical trial is to evaluate whether a multicomponent nurse-led intervention (BEST CARE ICTUS_HC) can reduce stroke-related complications and improve recovery in adults (18 years and older) hospitalized with an…
- Conditions
- Stroke, Acute Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- BESTCAREICTUS (NCT07627399)
- Testing
- BEST CARE ICTUS_HC BUNDLE
- Where
- 4 sites in Spain
- Volunteers
- 700 people
- Sponsor
- University of Malaga
Ischemic Stroke
Efficacy of High and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcome in Patients With AIS
Patients with acute ischemic stroke will be divided into 2 groups by double-blind, randomized, and controlled trial. Personality and past history of the patients will be recorded after the patients signed inform consent.
- Trial name
- NCT03402204
- Testing
- Simvastatin 10 mg, Simvastatin 40 mg
- Volunteers
- 64 people
- Sponsor
- Thammasat University
Ischemic Stroke
Selection Criteria in Endovascular Thrombectomy and Thrombolytic Therapy (SECRET) Study: Development of Patient Selection Criteria Using CT Images and Accompanying Diseases for Efficient Intravenous Thrombolytic and Intra-arterial Recanalization Therapy in Acute Ischemic Stroke
Use of intravenous (IV) thrombolysis and intra-arterial (IA) recanalization treatment has been rapidly increasing, However, despite of the treatment, recanalization rates are 22.6 - 70% and only 30-50% of patients show meaningful…
- Trial name
- NCT02964052
- Testing
- Brain CT imaging
- Where
- South Korea
- Volunteers
- 1,359 people
- Sponsor
- Yonsei University
Stroke
Acute Effects After Stretching Respiratory Muscles on Ventilatory Pattern and Volume Distribution of Chest Wall
The purpose of study is to evaluate the acute effects of respiratory muscles stretching on ventilator pattern and volume distribution of chest wall in patients with right hemiparesis post-stroke and our hypothesis is that the use…
- Trial name
- NCT02416349
- Testing
- Respiratory Muscles Stretching, Control Group
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Universidade Federal de Pernambuco