Clinical trials: Stroke Patients, open to volunteers
Stroke, Ischemic Stroke
Integrating Wearable Monitoring and Clinical Data for Stroke Early Warning
Stroke is a leading global cause of death and disability. In 2021 there were 11.9 million incident strokes (10.7-13.2 million) and 93.8 million prevalent stroke survivors (89.0-99.3 million) worldwide.
- Conditions
- Stroke, Ischemic Stroke, Recurrent Stroke, Transient Ischemic Attack
- Trial name
- WISE (NCT07908303)
- Testing
- Huawei HAY20, AI agent dialogue
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Affiliated Hospital of Nantong University
Ischemia Stroke, TIA (Transient Ischemic Attack)
Upfront Lipid-Lowering Therapy With Statins Combined With Hybutimibe in Patients With Acute Ischemic Stroke or Transient Ischemic Attack.
This study aims to evaluate whether an upfront combination lipid-lowering therapy (statins combined with hybutimibe) can further improve the 8-week LDL-C target achievement rate (<1.8 mmol/L and ≥50% reduction from baseline)…
- Trial name
- NCT07908875
- Testing
- Atorvastatin, Hybutimibe 10mg QD
- Volunteers
- 520 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Stroke
Effects of Upper Extremity Physiotherapy and Home Exercises on Functional Outcomes in Individuals With Stroke
This study aims to investigate the effects of an upper extremity physiotherapy program combined with home exercises on activities of daily living, quality of life, joint range of motion, and pain in individuals with hemiplegia…
- Trial name
- NCT07915141
- Testing
- Supervised Upper Extremity Physiotherapy Program, Home Exercise Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul Gelisim University
Carotid Atherosclerosis, Carotid Artery Stenosis Asymptomatic
PET-MR Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With 64Cu-NODAGA-CANF (Multisite)
The goal of this clinical trial is to evaluate the feasibility of imaging atherosclerosis by 64Cu-NODAGA-CANF PET-MR in a pilot study of patients with asymptomatic carotid artery stenosis (ACAS).
- Conditions
- Carotid Atherosclerosis, Carotid Artery Stenosis Asymptomatic, Asymptomatic Carotid Artery Stenosis
- Trial name
- NCT07916883
- Testing
- 64Cu-NODAGA-CANF
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Washington University School of Medicine
Chronic Stroke, Ischemic Stroke
Proof-of-concept for Use of Transcutaneous Spinal Stimulation (TSS) With the ExaStim® Stimulation System in Adults With Chronic Ischemic Stroke
The goal of this clinical trial is to learn about the safety, tolerability, and feasibility of ExaStim transcutaneous electrical stimulation combined with task-specific rehabilitation, and to characterize changes in arm function…
- Conditions
- Chronic Stroke, Ischemic Stroke, CVA (Cerebrovascular Accident)
- Trial name
- EXA2611 (NCT07917221)
- Testing
- Transcutaneous Spinal Stimulation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Atrial Fibrillation
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
REACT-AF is a multicenter prospective, randomized, open-label, blinded endpoint (PROBE design), controlled trial comparing the current Standard Of Care (SOC) of continuous Direct Oral Anticoagulation (DOAC) use versus…
- Trial name
- REACT-AF (NCT05836987)
- Testing
- AFSW Guided DOAC, Continuous DOAC therapy
- Where
- 93 sites in United States
- Volunteers
- 5,350 people
- Sponsor
- Johns Hopkins University
Healthy Individuals (Controls), Parkinson Disease
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.
- Conditions
- Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
- Trial name
- Allena-mente (NCT07066137)
- Testing
- CAREN, Control group
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Stroke
Electroacupuncture and rTMS for Post-Stroke Motor Recovery
This study aims to evaluate the combined efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) and Electroacupuncture (EA) in improving motor function recovery post-stroke, compared to rTMS combined with sham EA.
- Trial name
- NCT07113990
- Testing
- Active EA, Active rTMS
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- Jing Tao
Stroke
Functional Improvement in Subacute/Chronic Stroke Through Non-invasive Virtual-reality-Based Telerehabilitation
Stroke is the leading cause of disability in adults worldwide. Rehabilitation after a stroke is crucial, even after the acute phase: initially, it aims to recover the deficits caused by the stroke, but in the subacute/chronic…
- Trial name
- MUVITY (NCT07240948)
- Testing
- Non- immersive virtual reality (niVR)-based telerehabilitation home program
- Where
- Spain
- Volunteers
- 322 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Ischemic Stroke
Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Posterior Circulation Large Vessel Occlusion Stroke
This is an investigator-initiated phase III clinical trial employing a randomized, double-blind, placebo-controlled design. The primary objective of this study is to investigate the efficacy and safety of an interleukin-6…
- Trial name
- IRIS-3 (NCT07509645)
- Testing
- Tocilizumab
- Where
- 30 sites in China
- Volunteers
- 348 people
- Sponsor
- Capital Medical University
Intracranial Atherosclerotic Disease (ICAD), Hypertriglyceridaemia
Pemafibrate for Symptomatic ICAS RCT
The goal of this clinical trial is to learn whether pemafibrate can help prevent worsening of intracranial arterial stenosis (ICAS) in patients who have symptomatic ICAS and high triglycerides (TG) levels after ischemic stroke or…
- Conditions
- Intracranial Atherosclerotic Disease (ICAD), Hypertriglyceridaemia, Stroke (CVA) or TIA
- Trial name
- PPAR-ICAS (NCT07562178)
- Testing
- Pemafibrate
- Where
- 42 sites in Japan
- Volunteers
- 270 people
- Sponsor
- Tokyo Women's Medical University
Stroke
Effects of Jaw Clenching on Gait and Mobility in Stroke
The aim of this study is to investigate the immediate effects of jaw clenching on gait and functional mobility in patients with chronic stroke.
- Trial name
- NCT07612397
- Testing
- Voluntary Jaw Clenching
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bitlis Eren University
Memory Deficit Aquired Due to the Disease, e.g. Stroke, Neurodegeneration, Inflammatory Disease of CNS, Traumatic Brain Injury
Vestibular Stimulation in Sleep for Neurorehabilitation Patients
1. Why are we conducting this study? You are a patient of the neurorehabilitation clinic with one of the therapy focuses on memory and learning. Neuropsychological training is a standard therapeutic approach in this case.
- Trial name
- NCT07658027
- Testing
- Somnomat - rocking bed providing vestibular stimulation during sleep
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Cereneo AG
Hyperthermia
Rapid Cool: Heat Stroke Treatment
Hot climates such as in Phoenix, AZ commonly have individuals experiencing heat stroke, a life-threatening medical emergency. The dangerously high body temperature can result in death if not treated immediately with rapid body…
- Trial name
- NCT07743619
- Testing
- Recirculated water, Phoenix protocol
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Stroke, Ideomotor Apraxia
Post-Stroke Apraxia, Motor Function, Balance, and Gait
The goal of this observational study is to examine whether ideomotor apraxia is associated with motor function, balance, walking performance, and independence in daily activities in adults with hemiplegia after stroke.
- Conditions
- Stroke, Ideomotor Apraxia, Hemiplegia
- Trial name
- NCT07879807
- Testing
- Standardized clinical assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Izmir City Hospital
Stroke, Ideomotor Apraxia
Ideomotor Apraxia and Robotic Gait Rehabilitation Outcomes After Stroke
After a stroke, some people have difficulty planning and carrying out familiar movements. This difficulty is called ideomotor apraxia and cannot be explained by muscle weakness alone.
- Conditions
- Stroke, Ideomotor Apraxia, Hemiplegia
- Trial name
- NCT07881471
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir City Hospital
Acute Ischemic Stroke
Short-Term External Trigeminal Nerve Stimulation for Acute Ischemic Stroke: A Sham-Controlled Trial
The goal of this clinical trial is to evaluate the efficacy of a 5-day short-course external trigeminal nerve stimulation (eTNS) regimen in patients with acute ischemic stroke.
- Trial name
- NCT07911605
- Testing
- External trigeminal nerve stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xidian University
Stroke, Alzheimer s Disease
Development, Validation and Normative Data of the Italian Battery for the Recognition of Famous Faces (FAME)
The I-FACE project aims to develop and validate a battery to assess famous-face recognition in people with neurodegenerative diseases and stroke.
- Conditions
- Stroke, Alzheimer s Disease, Frontotemporal Degeneration (FTD)
- Trial name
- I-FACE (NCT07911878)
- Testing
- Neuropsychological assessment using the I-FACE battery
- Where
- 10 sites in Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Hemiparesis, Ischemic Stroke
Dynamic Stabilometry Combined With Transcranial Direct Current Stimulation for Balance and Motor Recovery After Ischemic Stroke
The goal of this clinical trial is to learn if balance training on a moving (dynamic) platform with visual and sound feedback, combined with weak electrical brain stimulation, helps people recover balance and movement after an…
- Conditions
- Hemiparesis, Ischemic Stroke, Stroke Rehabilitation, Postural Balance
- Trial name
- STAB-tDCS (NCT07912151)
- Testing
- Dynamic Stabilometry With Biofeedback, Static Stabilometry, Anodal tDCS
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Samara State Medical University
Aphasia, Stroke
Cerebellar Brain Stimulation Plus Language Therapy for People at Risk of Poor Aphasia Recovery After Stroke
This pilot study tests whether a mild form of brain stimulation to the cerebellum, combined with computer-based language therapy, helps people recover language after a stroke when a poor natural recovery is predicted.
- Conditions
- Aphasia, Stroke, Anomia
- Trial name
- PART-CN (NCT07912242)
- Testing
- Cathodal cerebellar transcranial direct current stimulation, Computerized language therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Johns Hopkins University