Clinical trials: Stroke Risk
Myocardial Infarction
Development and Validation of a Risk Prediction Model for Ischemic Stroke in Acute Myocardial Infarction Without Comorbid Atrial Fibrillation
Study Goal: This observational study aims to develop a tool to predict the risk of ischemic stroke(stroke caused by a blood clot) in people who survive a heart attack and do not have irregular heartbeats (atrial fibrillation) .
- Trial name
- NCT07171892
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- First Affiliated Hospital of Ningbo University
Cerebral Infarction
Study on Yangxue Nao Granules Reducing the Risk of Stroke
Objective: To explore the effectiveness of raising serum nao granules in reducing the risk of bleeding in patients with acute ischemic stroke treated with intravenous thrombolysis in the real world
- Trial name
- NCT04949906
- Testing
- Raise serum brain granules, No nourishing serum brain granules are used
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking University Third Hospital
Lacunar Stroke
The Relationship Between Controlling Risk Factors and Cerebral Haemodynamics in Lacunar Stroke
The goal of this observational study is to look at differences in brain blood flow before and after management of risk factors such as high blood pressure and diabetes in patients with lacunar stroke.
- Trial name
- LACUNAR_CA (NCT06354881)
- Testing
- Transcranial Doppler Ultrasonography (TCD) during sit-stand manoeuvres
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- University of Leicester
Atrial Fibrillation
RAPID AFib Decision Aid for Stroke Prevention in Atrial Fibrillation
The goal of this pilot clinical trial is to evaluate the utility of a new electronic patient decision aid for stroke prevention therapy in patients with atrial fibrillation.
- Trial name
- NCT05900414
- Testing
- Electronic patient decision aid, Information
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Carotid Stenosis
Lifestyle Modification Programme for Patients With Asymptomatic Carotid Artery Stenosis
This study randomises patients with patients with asymptomatic carotid artery stenosis, to be managed either by providing an intensive 12-week lifestyle modification programme, or standard healthcare.
- Trial name
- NCT03929354
- Testing
- Risk Factors Modification Programme, Standard Care
- Where
- Ireland
- Volunteers
- 208 people
- Sponsor
- Western Vascular Institute, Ireland
Hypotension, Postoperative Complications
Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery
Major adverse cardiovascular events (MACE) are a leading cause of serious complications and death following major noncardiac surgery.
- Conditions
- Hypotension, Postoperative Complications, Acute Coronary Syndrome, Heart Failure
- Trial name
- BBB (NCT02533128)
- Testing
- Liberal blood pressure management, Tight blood pressure management
- Where
- Switzerland
- Volunteers
- 458 people
- Sponsor
- Miodrag Filipovic, Prof. Dr. med.
Myocardial Infarction, Angina Pectoris
Improving Intermediate Risk Management. MARK Study
Cardiovascular risk functions fail to identify more than 50% of patients who develop cardiovascular disease. This is especially evident in the intermediate-risk patients in which clinical management becomes difficult.
- Conditions
- Myocardial Infarction, Angina Pectoris, Stroke, Peripheral Arterial Disease
- Trial name
- MARK (NCT01428934)
- Where
- Spain
- Volunteers
- 2,495 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Stroke, Atrial Fibrillation
B2AD-Risk AFDAS Evolution of Burden of AF
Each year, 7.8 million people worldwide experience an ischemic stroke, often caused by atrial fibrillation (AF). AF is a major contributor to severe, disabling, and deadly strokes.
- Trial name
- B2AD-Risk AF (NCT06589700)
- Testing
- Implantable Loop Recorder
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Luciano A. Sposato
Oneida Nation Members
Brain Health Oneida
The purpose of this observational study is to better understand the relationship between stroke risk factors and brain MRI measures in the Native American population.
- Trial name
- NCT07080866
- Testing
- MRI, Carotid ultrasound
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Wisconsin, Madison
Atrial Fibrillation
Efficacy and Safety of Aspirin and Clopidogrel in the Atrial Fibrillation With Low or Moderate Stroke Risk
This study was designed in order to evaluate and compare the efficacy and safety between aspirin and clopidogrel in the patient with low stroke risk Atrial Fibrillation (AF).
- Trial name
- CESAC-AF (NCT02960126)
- Testing
- Aspirin, Clopidogrel
- Volunteers
- 1,500 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Stroke
Effect of Sensorimotor Training Versus Dual-task Training
The aim of this study is to determine the comparative effects of sensorimotor training and dual-task training on propriocetion, balance, functional mobility and fall risk in stroke patients.
- Trial name
- NCT07628374
- Testing
- Sensorimotor Training, Dual-Task Training, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Atherosclerosis
Progression of Early Subclinical Atherosclerosis
The overall objective of this study is to characterize the prevalence and progression rate of subclinical atherosclerotic lesions and to study their association to the imaging characteristics of atheroma plaques and to the…
- Trial name
- PESA (NCT01410318)
- Where
- Spain
- Volunteers
- 4,184 people, healthy volunteers welcome
- Sponsor
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Stroke
Study on the Incremental Predictive Value of Early Resting-State EEG Phenotypes for Functional Prognosis and Risk Stratification in Acute Ischemic Stroke
This is a single-center, prospective, observational cohort study that plans to consecutively enroll 400 patients with acute ischemic stroke from July 2026 to July 2029.
- Trial name
- NCT07741669
- Where
- China
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Coronary Disease, Coronary Artery Bypass
Integrated Assessment of Cervicocerebral Vessels to Improve the Brain Injury for CAGB Patients (IACV Study)
The goal of this study is to establish a prospective study to focus on the high-risk stroke population who require coronary artery bypass graft surgery.
- Conditions
- Coronary Disease, Coronary Artery Bypass, Strokes Thrombotic
- Trial name
- NCT06275139
- Testing
- Integrated Assessment of Cervicocerebral Vessels
- Where
- China
- Volunteers
- 348 people
- Sponsor
- China National Center for Cardiovascular Diseases
Stroke
Effects of Occlusal Imbalance and Clenching on Balance in Stroke Patients
The aim of the study is to investigate the effects of stimulated occlusal imbalance and jaw clenching on balance and fall risk in patients with stroke.
- Trial name
- NCT07007429
- Testing
- Ipsilesional Side Stimulated Occlusal Imbalance, Contralesional Side Stimulated Occlusal Imbalance, Bilateral Cotton Roll with Jaw Clenching
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bitlis Eren University
Atherosclerosis, Carotid Artery Disease
Morphological and Serological Criteria of Plaque Vulnerability: Risk Assessment for Symptomatic and Asymptomatic Carotid Artery Stenosis
The aim of this study is to investigate the association of sonographic and histological features of the plaque among each other and with biomarkers of cardiovascular risk.
- Trial name
- VUCAP (NCT02124928)
- Testing
- Carotid endarterectomy
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Prim PD Dr Afshin Assadian
Acute Ischemic Stroke
An Application Provides Temperature-related Health Risk Warnings and Protective Recommendations on Stroke
This study applied an application to provide early warnings and advice for stroke patients and explored the impact of this intervention on reducing the risk of stroke recurrence
- Trial name
- NCT07097428
- Testing
- Temperature health risk early warning
- Volunteers
- 5,092 people
- Sponsor
- Xuanwu Hospital, Beijing
Cardiovascular Diseases, Cerebrovascular Accident
Homocyst(e)Ine, Vitamin Status, and CVD Risk
To test the hypotheses that the risk of myocardial infarction and/or stroke is associated with elevated plasma levels of homocysteine, and low plasma levels of folate, vitamins B12 and B6.
- Conditions
- Cardiovascular Diseases, Cerebrovascular Accident, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00005482
- Sponsor
- University of Washington
Ischemic White Matter Disease, Transient Ischemic Attack
Cognitive Changes and Rehabilitation in People With Transient Ischemic Attack, Stroke, or Stroke Risk Factors
Stroke is a leading cause of disability; most strokes (80%) are subcortical, with ischemic damage due to occlusion in penetrating arteries.
- Conditions
- Ischemic White Matter Disease, Transient Ischemic Attack, Mild Stroke, Stroke Risk
- Trial name
- NCT01951612
- Testing
- Executive Function Training Program, Psychoeducational Training Program
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Baycrest
Diabetes Mellitus, Hypertension
Impact of INsulin Sensitivity on Cardiovascular Risk Markers During 10-20 Years of FOllow up
The purpose of this study is to identify risk factors for insulin resistance and to investigate the influence of insulin sensitivity on development of cardiovascular risk markers like blood pressure, heart rate, body build…
- Conditions
- Diabetes Mellitus, Hypertension, Ischemic Heart Disease, Stroke
- Trial name
- INFO (NCT01412554)
- Where
- Norway
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital