Clinical trials: Stroke With Hemiparesis
Hemiplegia and/or Hemiparesis Following Stroke, Upper Extremity Injury
Upper Limb Treatment With "Gloreha Aria" in the Hemiplegic Patients
Stroke is one of the leading causes of death and disability and has been described as a worldwide epidemic (1). Stroke survivors are affected by impairments and limitations of cognitive, language, perceptual, sensory, and motor…
- Trial name
- NCT03738813
- Testing
- Gloreha Aria, Usual care
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Stroke, Cerebrovascular, Hemiplegia and Hemiparesis
BCI Driving FES and Hand Orthosis for Upper Limb Rehabilitation in Chronic Stroke
Multi-center, randomized, sham-controlled, double-blind, longitudinal, experimental clinical study to investigate functional recovery effects on the upper limb in chronic stroke patients and the accompanying neural plasticity…
- Conditions
- Stroke, Cerebrovascular, Hemiplegia and Hemiparesis, Stroke/Brain Attack
- Trial name
- NCT06179745
- Testing
- EEG-based brain-computer interface, Functional Electrical Stimulation, Active hand orthosis
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- University of Essex
Stroke, Cerebrovascular Accident
Combining Armodafinil With Neuro-rehabilitation to Improve Neurological Recovery and Reduce Disability Post-Stroke
Armodafinil is an FDA approved medication with wakefulness-promoting properties. It is a relatively safe agent with interesting neurochemical effects on the catecholamine system, producing an improvement in cognitive function…
- Conditions
- Stroke, Cerebrovascular Accident, Hemiparesis
- Trial name
- NCT01896128
- Testing
- Armodafinil
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Burke Rehabilitation Hospital
Upper Extremity Paresis, Hemiplegia and/or Hemiparesis Following Stroke
Task or Virtual Reality Intervention for Improving UE Function
People with one arm that does not function well due to a stroke, head injury, or cerebral palsy, and a fully functional other arm, will be randomly assigned to receive one of the two interventions first, followed by the other…
- Conditions
- Upper Extremity Paresis, Hemiplegia and/or Hemiparesis Following Stroke, Hemiplegic Cerebral Palsy
- Trial name
- NCT03811275
- Testing
- Virtual Reality (A) then Task (B), Task (B) then Virtual Reality (A)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Idaho State University
Nervous System Disorders
Dysport® Adult Upper Limb Spasticity
The purpose of this research study is to assess the efficacy of Dysport compared to placebo in improving muscle tone in hemiparetic subjects with upper limb spasticity due to stroke or traumatic brain injury.
- Trial name
- NCT01313299
- Testing
- Botulinum toxin type A
- Where
- 40 sites in United States, Belgium and 7 more
- Volunteers
- 243 people
- Sponsor
- Ipsen
Stroke, Hemiparesis
Effects of a Walking Intervention With Additional Weights on the Unaffected Leg in People After Stroke
This study is designed to determine if adding daily weighted braces on the unaffected ankle may benefit to patient who have returned home compare to a placebo intervention (ankle brace without weight).
- Trial name
- ANANTA (NCT01952522)
- Testing
- Weighted brace, Non weighted brace
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Strokes Thrombotic
Patient Education Program and Trunk Control Exercises in Post-stroke
The trunk movement awareness and education of individuals with post-stroke hemiparesis is not emphasized adequately in clinical practice.
- Trial name
- NCT06679699
- Testing
- Trunk control exercises combined with patient education program, Trunk control exercises
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- Gulf Medical University
Stroke
Combining Robotic-Assisted Therapy and Pharmacotherapy in Post-Stroke Rehabilitation
Stroke is the leading cause of acquired long-term disability in adults in developed countries. Despite aggressive rehabilitation, lasting upper extremity impairment remains in the majority of stroke survivors.
- Trial name
- NCT02346630
- Testing
- Levodopa / Carbidopa, Armeo
- Where
- United States
- Sponsor
- Ross D. Zafonte, MD
Spastic Hemiparesis
The Effect of a Self-rehabilitation Program in Addition to Usual Treatment for Spasticity on Impairment and Activity Limitation in Patients With Spastic Hemiparesis Following Stroke
The addition of a self-rehabilitation program to repeated Botulinum Toxin Injections (BTI) and usual physiotherapy should increase the proportion of patients who attain their Primary Treatment Goal (impairments and function) more…
- Trial name
- ADJU-TOX (NCT02944929)
- Testing
- Self-rehabilitation program
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke Sequelae
Virtual Reality Versus Constraint-induced Movement on Hemiparesis in Cerebrovascular Event
The objective of this clinical trial is to measure the effect of Rehabilitation with Virtual Reality or Modified Constraint-Induced Movement Therapy on hemiparesis in patients with Cerebral Vascular Event.
- Trial name
- NCT05875116
- Testing
- Virtual reality, Modified constraint-induced movement therapy, Usual Physical and Occupational Therapy
- Where
- Mexico
- Volunteers
- 119 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Stroke, Hemiplegia
rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke
This study is a necessary and important step in the development of a new therapy for upper limb functional recovery in patients with severe motor impairment.
- Conditions
- Stroke, Hemiplegia, Cerebrovascular Accident (CVA), Hemiparesis
- Trial name
- rTMS+CCFES (NCT03870672)
- Testing
- Contralaterally Controlled Functional Electrical Stimulation, New rTMS approach, Conventional rTMS approach
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- The Cleveland Clinic
Cerebrovascular Accident, Hemiparesis
Trial of Ropinirole in Motor Recovery After Stroke
The purpose of this study is to assess efficacy, as well as safety, of Ropinirole in improving movement among patients with chronic stroke.
- Trial name
- NCT00221390
- Testing
- Ropinirole (+ physical therapy)
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of California, Irvine
Stroke
Trunk Control Tests in Post-stroke Context: Validity and Reliability Study
Context: After stroke, most patients suffer from hemiparesis with variable functional consequences that can strongly impact autonomy in daily activities.
- Trial name
- NCT04639453
- Testing
- Trunk strength with hand-held dynamometer, Balance Assessment in Sitting and Standing test (BASS), Timed Up and Go test
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- Anne-Violette Bruynnel
Hemiplegia and/or Hemiparesis Following Stroke
Exercise to Improve Sleep and Quality of Life in Stroke Patients Receiving Botulinum Toxin Treatment
This study aimed to investigate the contribution of aerobic exercise programmes to improving sleep quality, quality of life, and functional status, alongside conventional rehabilitation, in stroke patients who had received…
- Trial name
- NCT07369453
- Testing
- Aerobic exercise training using a cycle ergometer
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Stroke
Treatment of Chronic Stroke With IpsiHand
The ultimate goal of this project is to develop a functioning and clinically feasible method for restoring function to motor-impaired stroke survivors. This ultimate goal will be approached through two different means.
- Trial name
- NCT02552368
- Testing
- IpsiHand Device
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Stroke With Hemiparesis, Perinatal Stroke
National Egyptian Network Pediatric Stroke and Hemiplegia Registry
Our aim is to establish multi-center national Egyptian database of information about cerebrovascular stroke and hemiplegia in infants and children from 0 to 18 years of age.
- Conditions
- Stroke With Hemiparesis, Perinatal Stroke, Focal Neurologic Deficits
- Trial name
- NCT02129491
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- Ain Shams University
Stroke, Ischemic, Stroke
Validation of a Brain-Computer Interface for Stroke Neurological Upper Limb Rehabilitation
The study's main goal is to determine if clinical and physiological effects of a brain-computer interface intervention for the neurorehabilitation of stroke patients' upper limb are greater than the effects of a sham robotic…
- Trial name
- NCT04724824
- Testing
- Brain-Computer Interface
- Where
- Mexico
- Volunteers
- 23 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Stroke with Hemiparesis, Stroke
Impact of the BOOST GAIT Program on Gait Recovery and Functional Mobility After Stroke
The overarching goal is to determine if the BOOST GAIT program can improve functional mobility in patients with stroke who are undergoing inpatient rehabilitation and have some walking function, through the application of…
- Trial name
- BOOST GAIT (NCT06612359)
- Testing
- BOOST GAIT Program
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Hasselt University
Stroke, Transcranial Direct Current Stimulation
Anodal Transcranial Direct Current Stimulation Over the Contralesional Hemisphere on Motor Recovery in Subacute Stroke Patients
Upper limb recovery is not predicted by the initial severity of paralysis and the parameters reflecting the integrity of the corticospinal tract (e.g. motor evoked potential, fractional anisotropy in diffusion tensor imaging).
- Conditions
- Stroke, Transcranial Direct Current Stimulation, Recovery of Function, Neurological Rehabilitation
- Trial name
- NCT03635008
- Testing
- tDCS
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Seoul National University Hospital
Stroke, Hemiparesis
Motor Learning for Upper Limb Hemiparesis After Stroke
The purpose of this research is to learn about practice conditions that may benefit stroke survivors when learning to use their more affected arm to perform a task. Participants will be randomized into two groups.
- Trial name
- NCT05765474
- Testing
- Practice Variable, No Practice Variable
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Columbia University