Clinical trials: Strokes
Cerebrovascular Accident
Post-Stroke Improvement of Motor Function
Open-label clinical study where all new patients presenting with cerebrovascular accidents and consenting to treatment are given intravenously a new combination of medications.
- Trial name
- PSIOM (NCT03543917)
- Testing
- Perfusion with New Combination Medication
- Where
- Romania
- Volunteers
- 17 people
- Sponsor
- Fundatia Bio-Forum
Traumatic Brain Injury, Subarachnoid Hemorrhage
Comparison of Narcotrend and Cerebral Function Analysing Monitor in Intensive Care to Monitor Seizures and Deep Sedation
A study in the use of the Narcotrend depth of anaesthesia monitor to record a) seizures, and b) monitor a level of sedation referred to as 'burst suppression', in sedated patients in the adult and paediatric intensive care.
- Conditions
- Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Haemorrhage, Encephalitis
- Trial name
- NCT06067750
- Testing
- Narcotrend compared to Cerebral Function Analysing Monitor (CFAM)
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Acute Ischemic Stroke
rhPro-UK in Acute Ischaemic Stroke Within 4.5 Hours of Stroke Onset Trial 2(PROST-2)
Intravenous thrombolysis is the first-line therapy in patients with acute ischemic stroke within 4·5 hours of symptom onset, and recombinant tissue plasminogen activator (alteplase) is the preferred thrombolytic agent for this…
- Trial name
- PROST-2 (NCT05700591)
- Testing
- rhPro-UK, rt-PA
- Where
- 72 sites in China
- Volunteers
- 1,552 people
- Sponsor
- Tasly Biopharmaceuticals Co., Ltd.
Ischemic Stroke, Intracerebral Hemorrhage
China Stroke Registry for Patients With Traditional Chinese Medicine
The CASES-TCM study is a prospective, multicenter, observational study, which will enroll 20,000 patients with acute stroke (ischemic stroke or intracerebral hemorrhage) within 7 days of symptom onset.
- Trial name
- CASES-TCM (NCT04921397)
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Dongzhimen Hospital, Beijing
Stroke
Implantable Brain-Computer Interface for Upper-Limb Recovery After Stroke
The clinical investigation will take place in three phases: A pre-selection/selection phase to ensure that the patient (lesion, symptoms, ability of our tools to detect your movement intentions, etc.) is suitable for a six-month…
- Trial name
- BCI4STROKE-Arm (NCT07477613)
- Testing
- BCI
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Grenoble
Stroke
"Mobile Stroke-Unit" for Reduction of the Response Time in Ischemic Stroke
Stroke, the most common cause of permanent disability, the second most common cause of dementia and third most common cause of death, has tremendous socio-economic consequences.
- Trial name
- MSU (NCT00792220)
- Testing
- MSU, OCCM
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital, Saarland
Chronic Stroke
Effect of Kinesiotape Technique on Wrist Among Chronic Stroke Patients
The aim of this randomized controlled is to assess the effect of kinesiotape technique upon wrist joint among the patients with chronic stroke.
- Trial name
- NCT05526859
- Testing
- Kinsiotaping for wrist flexor muscles, Kinesiotaping for wrist extensor muscles
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Shifa Tameer-e-Millat University
Embolic Stroke of Undetermined Source
Apixaban for Treatment of Embolic Stroke of Undetermined Source
Multicentre (national, Germany), randomized (2x2 factorial), open, parallel group, active controlled, efficacy study (phase III)
- Trial name
- ATTICUS (NCT02427126)
- Testing
- Apixaban, Aspirin
- Where
- 16 sites in Germany
- Volunteers
- 352 people
- Sponsor
- University Hospital Tuebingen
Acute Ischemic Stroke
Safety and Efficacy Evaluation of the iNstroke 4F Thromboaspiration Catheter in Patients With Acute Ischaemic Stroke Due to Primary Distal Medium Vessel Occlusions (DMVO)
Prospective, Single-arm, Multi-centre Study to Evaluate the Efficacy and Safety of the iNstroke 4F Thromboaspiration Catheter in Patients with Acute Ischaemic Stroke due to Primary Distal Medium Vessel Occlusions.
- Trial name
- 4-NiVO (NCT07357285)
- Testing
- Thromboaspiration catheter
- Where
- 11 sites in Germany, Hungary and 1 more
- Volunteers
- 57 people
- Sponsor
- iVascular S.L.U.
Stroke, Hypertension
Family at Risk Study
Atherosclerotic cardiovascular disease (ASCVD) risk factors include hypertension as a key risk factor, as well as hyperlipidemia, diabetes, smoking, obesity, diet, inactivity, family history and age.
- Trial name
- FAR (NCT04607876)
- Testing
- Technological Facilitator, Standard of Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Stroke, Spinal Cord Injuries (SCI)
ZEPU-AI1 Gait Robot Training Study (ZEPUAI1RCT)
Walking problems caused by stroke, spinal cord injury, or orthopedic surgery are common and can seriously limit a person's independence.
- Conditions
- Stroke, Spinal Cord Injuries (SCI), Gait Disorders, Neurologic
- Trial name
- NCT07735676
- Testing
- ZEPU-AI1 Gait Training and Evaluation System, Standard-of-Care Rehabilitation (Individualized Rehabilitation and Exercise)
- Where
- Bangladesh
- Volunteers
- 51 people
- Sponsor
- Bangladesh Medical University
Stroke, Ischemic
A Clinical Study of iEPC Intervent Subjects With Cerebral Hemorrhagic Stroke
This is a single centre、single arm、open-label，to investigate the safety and efficacy of EPC transplantation in the brain
- Trial name
- NCT03726814
- Testing
- EPC treatment group
- Volunteers
- 12 people
- Sponsor
- Allife Medical Science and Technology Co., Ltd.
Hemiplegic Shoulder Pain
Effectiveness of High-intensity Peripheral Magnetic Stimulation on Hemiplegic Shoulder Pain After Stroke
This study aims to investigate the effectiveness of high-intensity electromagnetic stimulation using the BTL-6000 Super Inductive System (SIS) in the management of hemiplegic shoulder pain in patients with stroke.
- Trial name
- NCT07912138
- Testing
- Active Peripheral Magnetic Stimulation
- Volunteers
- 30 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Cerebral Stroke, Cerebral Venous Thrombosis
Intracranial Hypertension and Optic Nerve Sheath Diameter
Intracranial hypertension (ICH) is a mortality risk factor in severe traumatic brain injury (TBI), in purulent meningitis, in hepatic encephalopathy and in Reye's syndrome.
- Trial name
- DENO (NCT01796015)
- Testing
- ONSD ultrasound
- Where
- 2 sites in France
- Volunteers
- 230 people
- Sponsor
- Hospices Civils de Lyon
Stroke, Hypertension
Renal Denervation Hypertension After Stroke
It is known, that hypertension is the major risk factor of stroke and recurrent stroke. Blood pressure reduction - together with antithrombotics - remain crucial in stroke prevention.
- Trial name
- REHEARSE (NCT01689415)
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Bispebjerg Hospital
Stroke
Effects of Gait Training With Assistance of a Robot-Driven Gait Orthosis in Hemiparetic Patients After Stroke
The purpose of this study is to investigate the effects of robot-assisted gait training on active walking in the patients with stroke.
- Trial name
- NCT00530543
- Testing
- Robot-assisted gait training
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Stroke, Hemiplegia
Effects of Mirror Therapy and Bilateral Arm Training on Hemiparetic Upper Extremity in Patients With Chronic Stroke
The aim of this study included (1) to compare the effectiveness of mirror therapy (MT) and bimanual arm training (BAT) in improving motor and functional performance of hemiplegic upper extremity for adults with chronic stroke…
- Trial name
- NCT04242316
- Testing
- Mirror Therapy, Bilateral arm training
- Volunteers
- 101 people
- Sponsor
- The Hong Kong Polytechnic University
Cerebrovascular Accident, Deglutition Disorders
Toronto Bedside Swallowing Screening Test (TOR-BSST) - A Bedside Swallowing Screening for Stroke Patients
This research will assess the accuracy of the Toronto Bedside Swallowing Screening Test (TOR-BSST), a new dysphagia screening test for patients with stroke.
- Trial name
- NCT00141752
- Testing
- Toronto Bedside Swallowing Screening Test (TOR-BSST)
- Where
- 5 sites in Canada
- Volunteers
- 311 people
- Sponsor
- University Health Network, Toronto
Stroke, Neurologic Diseases, General
Cerebril™ in Patients With Lobar Hemorrhage Related to Cerebral Amyloid Angiopathy
The main objective of this study is to evaluate the safety, tolerability and pharmacokinetics of Cerebril™ in Cerebral Amyloid Angiopathy (CAA) patients who have had lobar cerebral hemorrhage.
- Trial name
- NCT00056238
- Testing
- NC-758 (Anti amyloidotic [Aß] agent)
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Bellus Health Inc. - a GSK company
Stroke, Ischemic Stroke
Optimizing Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke
SELECT is a multicenter, observational prospective study implementing a protocol to acquire imaging and clinical variables known to affect clinical outcomes after endovascular therapy in an effort to evaluate and compare the…
- Trial name
- SELECT (NCT02446587)
- Testing
- Mechanical Thrombectomy
- Where
- 9 sites in United States
- Volunteers
- 500 people
- Sponsor
- The University of Texas Health Science Center, Houston
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