Clinical trials: Strokes
Spinal Cord Infarction, Spinal Cord Stroke
Descriptive Study of Acute Spontaneous Spinal Cord Infarction
Acute spontaneous Spinal Cord Infarctions (SCI) are an uncommon cause of myelopathy (5%), but their prognostic is heterogeneous and frequently severe. Positive diagnosis is difficult, one quarter of initial MRIs are normal.
- Conditions
- Spinal Cord Infarction, Spinal Cord Stroke, Vascular Myelopathy
- Trial name
- EDMIAS (NCT04372758)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Stroke
Optimizing Current and Electrode Montage for Transcranial Direct Current Stimulation in Stroke Patients
The purpose of this study is to determine the optimal transcranial direct current stimulation (tDCS) amplitude and electrode montage that is both safe and efficacious
- Trial name
- COBRE_JIpro3 (NCT02763826)
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Medical University of South Carolina
Stroke
ThRombectomy In Mild Ischemic Stroke With a Visible Intracranial veSsel Occlusion
The purpose of TRIMIS is to study how a medical procedure by the name of endovascular therapy compares to medical treatment alone in patients with mild stroke and a blood vessel occlusion in the brain
- Trial name
- TRIMIS (NCT06778226)
- Where
- 3 sites in United States
- Volunteers
- 4,827 people
- Sponsor
- University of Miami
Stroke
Stroke Prevention and Treatment System in Shanghai: a Network of Public Healthcare of Stroke
The Shanghai Stroke Service System(4S) has been established as the network of stroke care in greater Shanghai metropolitan area.
- Trial name
- SSSS (NCT02735226)
- Testing
- stroke network and policy intervention
- Where
- 11 sites in China
- Volunteers
- 100,000 people
- Sponsor
- Shanghai Stroke Service System
Stroke, Stroke Ischemic
duoABLE for People With Stroke and Their Caregivers
The goal of this intervention study is to test whether a behavioral program that involves people with stroke and their caregivers is acceptable, safe, and can promote physically active lifestyles using enjoyable activities.
- Conditions
- Stroke, Stroke Ischemic, Stroke Hemorrhagic, Stroke Sequelae
- Trial name
- NCT05964400
- Testing
- duoABLE
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Minnesota
Stroke
A Neurofeedback Interface in Poststroke Neuromodulation Using TMS-fNIRS
Stroke is a type of cerebrovascular disease, and the primary characteristic of post-stroke brains is pathological changes in cerebral hemodynamics.
- Trial name
- NCT07088107
- Testing
- fNIRS-triggered TMS
- Where
- 2 sites in Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Post Stroke
Combined Effects Of Sensory Integration And Vestibular Exercises On Post-Stroke Patients
The aim of this study is to determine the combined effects of sensory integration and vestibular exercise on dizziness, fall risk and quality of life.
- Trial name
- NCT06500611
- Testing
- Sensory Integration and Vestibular Exercise with Routine Physical Therapy, Vestibular Exercise with Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Atrial Fibrillation, Deep Vein Thrombosis
Weekly Monitoring Strategy of Capillary INR Versus Monthly Monitoring Strategy of Venous INR in Elderly Patients in a Nursing Home.
This primary care study aims to compare the "time in therapeutic range" (TTR) of two strategies for monitoring the international normalized ratio (INR) over 6 months in nursing homes.
- Conditions
- Atrial Fibrillation, Deep Vein Thrombosis, Stroke
- Trial name
- INR-CAP (NCT05561244)
- Testing
- Weekly monitoring using the capillary International Normalised Ratio strategy
- Where
- 33 sites in France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Healthy, Stroke
Error-augmented Walking on Gait Performance and Brain Activities in Stroke
This three-year study is proposed to document the effect and further implementation of error-augmented walking on gait performance and brain activities in individuals with stroke.
- Trial name
- NCT04455334
- Testing
- Error-augmented treadmill training, active control group, Error-augmented concept combined physical therapy group
- Where
- Taiwan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke
Cytoflavin in the Complex Rehabilitation of Stroke Patients
It is known that the acute period of stroke occurs is accompanied by oxidative stress, when intense generation of reactive oxygen species (ROS) have a toxic effect, which causes oxidative degradation of proteins, lipids, nucleic…
- Trial name
- NCT05935787
- Testing
- Cytoflavin (Inosine + Nicotinamide + Riboflavin + Succinic Acid)
- Where
- 3 sites in Russia
- Volunteers
- 240 people
- Sponsor
- POLYSAN Scientific & Technological Pharmaceutical Company
Stroke/Brain Attack, Upper Extremity Paresis
Tendon Vibrations Effect on Upper Limb Motor Recovery After Recent Stroke
Stroke is the leading cause of severe acquired disabilities in adults. It can affect sensory and motor functions which are closely entangled. Among them, upper limb function is often strongly impaired.
- Trial name
- VIBRAMOT (NCT04504214)
- Testing
- Upper limb repeated multi-site tendon vibrations
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Borelli UMR 9010
Stroke, Intracerebral Hemorrhage Lobar
Neuroendoscopic Hematoma Evacuation Combined With Methylprednisolone Sodium Succinate in the Treatment of Lobar Intracerebral Hemorrhage at the Early Stage.
The aim of this trial is to investigate whether neuroendoscopic hematoma evacuation combined with early use of methylprednisolone sodium succinate can improve the efficacy and safety in the treatment with that of simple…
- Conditions
- Stroke, Intracerebral Hemorrhage Lobar, Methylprednisolone, Surgery
- Trial name
- HEMS (NCT06921616)
- Testing
- Simple neuroendoscopic hematoma evacuation, Neuroendoscopic hematoma evacuation combined with sodium methylprednisolone succinate
- Where
- China
- Volunteers
- 396 people
- Sponsor
- Yong Jiang
Angiogenesis, Ischemic Stroke
Neovascularization Induced by Mechanical Barrier disrUption and Systemic Erythropoietin in Patients With Cerebral Perfusion Deficits
Neovascularization Induced by Mechanical Barrier disrUption and Systemic erythropoietin in patients with cerebral perfusion deficits (NIMBUS trial)
- Trial name
- NIMBUS (NCT02603406)
- Testing
- erythropoietin
- Volunteers
- 44 people
- Sponsor
- Ajou University School of Medicine
LVAD (Left Ventricular Assist Device) Thrombosis, LVAD
STudy of Aspirin Removal in Patients Supported by the Fully Magnetically Levitated CH-VAD Pump
This multi-center, prospective, randomized, double-blinded, placebo-controlled study aims to investigate whether withdrawal of aspirin from the antithrombotic regimen in patients supported with the CH-VAD pump is non-inferior to…
- Conditions
- LVAD (Left Ventricular Assist Device) Thrombosis, LVAD, LVAD (Left Ventricular Assist Device), LVAD-related GI Bleed
- Trial name
- STAR (NCT07644247)
- Testing
- Warfarin (INR 2-3) with aspirin
- Volunteers
- 370 people
- Sponsor
- China National Center for Cardiovascular Diseases
Stroke, Gait Disorders, Neurologic
Robot Walking Rehabilitation in Stroke Patients
Stroke are the main causes of motor disability among adults and are expected to impose an increasing social and economic burden for our Country.
- Trial name
- RoboSTROKE (NCT01678547)
- Testing
- Robot-assisted walking, Treadmill Training, Ground treatment
- Where
- 2 sites in Italy
- Volunteers
- 28 people
- Sponsor
- IRCCS San Raffaele Roma
Stroke
Home-based Balance Training Using Wii Fit After Stroke: A Feasibility Study
BACKGROUND: Virtual gaming systems offer new possibilities for home-based exercises (HBE) in rehabilitation. Pilot studies with stroke patients indicate that the application of Nintendo Wii® (WII) is practicable and can improve…
- Trial name
- WiiMobil (NCT02251470)
- Testing
- HBE Wii (EG), HBE Control (CG)
- Where
- 2 sites in Germany
- Volunteers
- 14 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Acute Ischemic Stroke
Clopidogrel Preventive Effect Based on CYP2C19 Genotype in Ischemic Stroke
The hypothesis of this study is that "the poor metabolizer or intermediate metabolizer of the cytochrome P450 2C19 genotype in patients with acute ischemic stroke is associated with increased risk of composite cardiovascular…
- Trial name
- NCT04072705
- Testing
- General principles of care and judgement of researcher
- Where
- 37 sites in South Korea
- Volunteers
- 2,927 people
- Sponsor
- Gangnam Severance Hospital
Stroke Rehabilitation, Postural Equilibrium
Study Evaluating the Effect of Moving Virtual Scenes on Postural Balance in a Stroke Rehabilitation Setting
This is an interventional, prospective, randomized, monocentric study designed to develop medical knowledge. Virtual reality is increasingly used in rehabilitation.
- Trial name
- VR-REACT (NCT06053970)
- Testing
- Assessing postural responses induced by visual stimulation (Visual Evoked postural responses, VEPR)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- FondationbHopale
Stroke Patients
Sonographic Evaluation of the Effect of Shoulder Orthosis on the Subluxation in Stroke Patients
Shoulder pain is frequently reported as a complication among stroke patients. Muscular imbalance disrupts stability of the glenohumeral joint creating a subluxation.
- Trial name
- SinSbyS&Co (NCT02102269)
- Testing
- actimove sling, shoulderlift
- Where
- 2 sites in Belgium
- Volunteers
- 23 people
- Sponsor
- University Hospital, Ghent
Acute Ischemic Stroke
Safety and Efficacy of Levofloxacin Combined With Intravenous Thrombolysis for Acute Ischemic Stroke
The purpose of this study is to determine the efficacy and safety of levofloxacin combined with intravenous thrombolysis in treating acute ischemic stroke
- Trial name
- NCT05741905
- Testing
- Levofloxacin, Levofloxacin simulant
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yi Yang
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