Clinical trials: Strokes
Stroke, Rehabilitation
Patient Engagement Program for Stroke - Pilot Study
Currently there is a lot of literatures on stroke rehabilitation and post-discharge therapy. However, there are few evidence based guidelines on patient engagement after stroke in the post-rehabilitation community phase.
- Trial name
- PEPS (NCT01112488)
- Testing
- Patient Engagement Programme
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Kowloon Hospital, Hong Kong
Stroke
Foot Drop Rehabilitation and Mobility in Chronic Stroke
Stroke is a leading cause of long-term disability, frequently resulting in motor impairments, balance deficits, and walking difficulties that limit functional independence and quality of life.
- Trial name
- NCT07914413
- Testing
- Conventional Physical Therapy Program, FES-Assisted Gait Training
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Umm Al-Qura University
Stroke
Anti-platelet Precision Medicine to Prevent Stroke Early Progression and Recurrence (PRECISE)
This is a pragmatic, multi-center, non-interventional, non-randomized prospective observational study.
- Trial name
- NCT03701360
- Where
- South Korea
- Volunteers
- 1,199 people
- Sponsor
- Asan Medical Center
Stroke, Endovascular Thrombectomy
Multidimensional Evaluation of Patients With Acute Ischemic Stroke Undergoing Pharmacological and Endovascular Revascularization Procedures for the Identification of Positive Prognostic Factors
In developed countries, stroke is the third leading cause of death and the leading cause of permanent disability. Systemic and endovascular thrombolytic treatments in acute cerebral ischemic stroke caused by occlusion of large…
- Conditions
- Stroke, Endovascular Thrombectomy, Ischemic Stroke
- Trial name
- NCT05708079
- Testing
- Endovascular thrombectomy
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sarcopenic Obesity, Spinal Cord Injuries
Sarcopenic Obesity in Neurodisabilities
To describe the frequency and thresholds for sarcopenic obesity in neurodisabled persons and the fat and lean mass distribution based on various neurodisabilities
- Conditions
- Sarcopenic Obesity, Spinal Cord Injuries, Stroke, Multiple Sclerosis
- Trial name
- SarcObeNDS (NCT03863379)
- Testing
- whole body DXA
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dionyssiotis, Yannis, M.D.
Sarcopenia
Measurement of Sarcopenia at Post-stroke Rehabilitation Outcome
The purposes of this study are 1. To explore effect of sarcopenia on recovery of post stroke hemiplegia 2. To explore the effect of stroke on sarcopenia and relationship between the degree of sarcopenia and respiration and…
- Trial name
- NCT02793362
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bucheon St. Mary's Hospital
Stroke, Hemiplegia
Effects of Whole-body Vibration Exercise on Stroke Patients
The purpose of this study is to investigate the effect of the whole body vibration exercise on cortical activity and gait function in patients with chronic stroke.
- Trial name
- NCT03375346
- Testing
- Whole body vibration, Exercise
- Volunteers
- 29 people
- Sponsor
- Samsung Medical Center
Stroke
Use of BCAA-rich Protein Supplements for Chronic Stroke Patients
In the past few years, Branched Chain Amino Acid (BCAA) supplements have gradually used on different groups. From training athletes, maintaining functions of healthy elders to preventing disabilities of people that can't do…
- Trial name
- NCT03244527
- Testing
- BCAA supplement, Aerobic exercise
- Where
- 2 sites in Taiwan
- Volunteers
- 20 people
- Sponsor
- Taipei Medical University WanFang Hospital
Atrial Fibrillation
Non-pharmacological Prevention of Stroke in Patients With Non-valvular Atrial Fibrillation
Left atrial appendage (LAA) occlude devices are used for over ten years. According to current data efficiency and safety of this approach at least comparable with pharmacological prevention of stroke in patients with non-valvular…
- Trial name
- NCT03867227
- Testing
- left atrial appendage occluder implantation
- Where
- Russia
- Volunteers
- 300 people
- Sponsor
- National Research Center for Preventive Medicine
Acute Stroke
A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients
This study was jointly developed and is jointly led by investigators at Massachusetts General Hospital and the intramural division of NINDS.
- Trial name
- MR WITNESS (NCT01282242)
- Testing
- IV rt-PA
- Where
- 14 sites in United States
- Volunteers
- 88 people
- Sponsor
- Lee Schwamm
Stroke Ischemic
Tenecteplase in ReperfUsion Therapy for Posterior Circulation Stroke With Extended Time Window: the TRUST Trial
The primary hypothesis being tested in this trial is that ischemic stroke patients in posterior circulation at 4.5 - 24 hours post onset of stroke will have improved clinical outcomes when given intravenous TNK compared to…
- Trial name
- NCT07073469
- Testing
- Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg), Standard medical treatment
- Volunteers
- 330 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ischemic Stroke, Stroke
Clinical Evaluation of EEG Device for the Triage of Stroke Patients in the Ambulance
Endovascular thrombectomy (EVT) is the standard treatment for large vessel occlusion (LVO) strokes, but it can only be performed in specialized hospitals.
- Conditions
- Ischemic Stroke, Stroke, Cardiovascular Diseases, Vascular Diseases
- Trial name
- CROSSROADS-EEG (NCT06871969)
- Testing
- Dry electrode EEG
- Where
- Netherlands
- Volunteers
- 275 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Stroke, Neglect, Hemispatial
Head Mount Display-based Virtual Reality Rehabilitation of Hemispatial Neglect
Head-mounted display based virtual reality rehabilitation for hemispatial neglect.
- Trial name
- NCT03463122
- Testing
- field of regard-focused visual exploration therapy, conventional therapy
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- National Rehabilitation Center, Seoul, Korea
Atherosclerosis
Accelerated Atherosclerosis in High Risk Population Groups: An Assessment by Magnetic Resonance Imaging
The goal of this study is to assess a slimy substance that settles/deposits along blood vessel wall. This slimy substance is called plaque. Plaque could be made up of fat, calcium or both. Plaque deposition narrows the vessels.
- Trial name
- NCT02114697
- Testing
- Statin therapy, Lifestyle modification
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Emory University
Ischemic Stroke
Methanesulfonic Acid Cinepazide Injection for Treatment of Acute Cerebral Infarction
Using placebo as control, The purpose of this study is to evaluate the efficacy and safety of methanesulfonic acid cinepazide injection to relieve disabled degree of acute cerebral infarction patients, and explore the best safe…
- Trial name
- NCT01851759
- Testing
- cinepazide
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Xijing Hospital
Acute Ischemic Stroke
Study to Evaluate The Safety and Efficacy of Balovaptan in Participants With Acute Ischemic Stroke at a High Risk of Developing Malignant Brain Edema
This study is designed to evaluate the safety, efficacy, and pharmacokinetics of balovaptan compared with placebo in participants with acute ischemic stroke (AIS) at risk of developing Malignant Cerebral Edema (MCE)
- Trial name
- NCT05399550
- Testing
- Balovaptan
- Where
- United States
- Sponsor
- Hoffmann-La Roche
Intravenous, Thrombosis
Intravenous TNK vs TPA for AIS Treatment on MSU,a Prospective Multicenter RCT
Acute ischemic stroke is one of the devastating diseases that increase hospitalization, disabilities, and deaths worldwide. Current treatment with intravenous thrombolytic agent can help reduce disabilities and improve quality of…
- Conditions
- Intravenous, Thrombosis, Acute Ischemic Stroke
- Trial name
- NCT06498323
- Testing
- tenecteplase
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Stroke, Cardiovascular Risk Factors
Exercise and Brain Health
The risk of stroke and vascular dementia is high in individuals who have had a prior stroke or TIA, and in those who have vascular disease risk factors, such as high blood pressure, abnormal cholesterol, diabetes or pre-diabetes.
- Conditions
- Stroke, Cardiovascular Risk Factors, Transient Ischemic Attack (TIA)
- Trial name
- EBH (NCT02626442)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Baltimore VA Medical Center
Stroke, Ischemic, Stroke, Acute
Ischemic Strokes While on NOAC - How Compliance Matters
This study is aimed to depict the epidemiological trend, aetiologies, clinical characteristics, treatment options of IS-NOAC in face of the rapidly increasing NOAC usage.
- Conditions
- Stroke, Ischemic, Stroke, Acute, Stroke Syndrome, Stroke, Cardiovascular
- Trial name
- NCT04607070
- Where
- Hong Kong
- Volunteers
- 91 people
- Sponsor
- Chinese University of Hong Kong
Stroke, Ischemic
Rescue Thrombolysis for Medium Vessel Occlusion (RESCUE-TNK)
The best reperfusion strategy for medium-sized vessel occlusion (MeVO) is not well established. Given the proven treatment effect of intra-arterial thrombolysis in patients with large vessel occlusion (LVO), the investigators…
- Trial name
- NCT05657470
- Testing
- Tenecteplase
- Where
- China
- Volunteers
- 80 people
- Sponsor
- General Hospital of Shenyang Military Region
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