Clinical trials: Strokes
Atrial Fibrillation (AF)
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
This study is researching experimental drugs called REGN7508 and REGN9933. The study is focused on participants who have atrial fibrillation, which means that the heart beats too fast and unevenly.
- Trial name
- ROXI-ATLAS (NCT07175428)
- Testing
- REGN7508, REGN9933, Apixaban
- Where
- 89 sites in United States, Argentina and 2 more
- Volunteers
- 1,200 people
- Sponsor
- Regeneron Pharmaceuticals
Dementia, Stroke
Facilitating Caregiver Adaptation to Patient Institutionalization
This study will assess the effects of an intervention targeting family caregivers who recently placed a relative in a long-term care facility because of cognitive and/or physical disability.
- Conditions
- Dementia, Stroke, Heart Disease
- Trial name
- FACTS (NCT01194128)
- Testing
- Psychoeducational Support, Information only control group
- Where
- United States
- Volunteers
- 217 people
- Sponsor
- University of Pittsburgh
Hemiparesis, Stroke Sequelae
Neural Mechanisms of Motor Recovery With Technology Assisted Training
Stroke is a leading cause of disability that often impairs arm function and activities of daily living. The costs of rehabilitation are significant and practical constraints often limit therapy to the first few months after…
- Trial name
- NCT05560867
- Testing
- robot-assisted training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Maryland, Baltimore
Acute Coronary Syndrome, Atrial Fibrillation
Short- and Long-term Health Effects of Air Pollution in Poland
The effects of air pollution on the frequency of hospital admissions and mortality due to acute coronary syndromes, atrial fibrillation, and renal disfunction are noted also in areas perceived as pollution-free (due to the lack…
- Conditions
- Acute Coronary Syndrome, Atrial Fibrillation, Kidney Diseases, Particulate Matter Inhalation Injury
- Trial name
- EP-PARTICLES (NCT05198492)
- Testing
- Impact of air pollution
- Where
- Poland
- Volunteers
- 8,300,000 people
- Sponsor
- Medical University of Bialystok
Atrial Fibrillation, Myocardial Infarction, Acute
Prognostic Role of LA Strain in Acute Myocardial Infarction
This is a single-center retrospective observational study in which we consecutively selected patients diagnosed with acute myocardial infarction from September 2019 to March 2024 at the Affiliated Hospital of Xuzhou Medical…
- Conditions
- Atrial Fibrillation, Myocardial Infarction, Acute, Stroke Ischemic, Mortality
- Trial name
- CMR-MI (NCT06408636)
- Testing
- Cardiac MRI
- Where
- China
- Volunteers
- 780 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Stroke
Metacognitive-Strategy Training in Sub-Acute Stroke
The long-term goal of this research is to improve activity performance and reduce motor impairment in individuals with stroke. Contemporary stroke rehabilitation focuses on remediation of post-stroke impairments with a false…
- Trial name
- NCT04099511
- Testing
- Usual Care Occupational Therapy-Outpatient, Cognitive Orientation to daily Occupational Performance
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Missouri-Columbia
Stroke
A Mobile Brain/Body Imaging Platform for the Assessment and Optimization of Post-stroke Overground Robotic Gait Treatments
The study aims to identify neural biomarkers that can be used to monitor the recovery of locomotion and movement of post-stroke patients, both in natural settings and with enriched treatment using robotic device.
- Trial name
- COBI (NCT07510633)
- Testing
- overground wearable robotic device
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Franco Molteni
Stroke, Acute
Hemodynamic Response and Motor Functions Following Transcranial Direct Current Stimulation in Acute Stroke
The aim of the present study is to evaluate the possible effect of using dual-tDCS applied before conventional physical therapy on motor functions and hemodynamic response
- Trial name
- NCT04051658
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Mahidol University
Stroke, Electroencephalogram
CEEG Changes After Tdcs and Dual-task Training
Stroke has been considered one of the main causes of long-term disability in the adult population. Technological advances in the neurological area have been observed in the last decades, which accentuates the interest in…
- Trial name
- NCT05492435
- Testing
- transcranial direct current stimulation
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- Federal University of Paraíba
Stroke
A Prospective Investigation of the VWF-ADAMTS 13 Axis in Acute Ischaemic Brain Injury (TIAs and Stroke).
In patients presenting with acute stroke or transient ischaemic attacks (TIA), von Willebrand factor related parameters, including VWF antigen, activity, FVIII:c and propeptides, ADAMTS13 levels and VWF multimers in cases where…
- Trial name
- NCT02219035
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University College, London
Lower Limb; Sprain (Strain), Lower Limb Fracture
Implementation of an App-based Walking Aid Skills Training Program
Walking aids (WA), such as crutches, canes, and walkers allow individuals to move independently after lower body impairment. Improper WA use may lead to upper body discomfort, pain, or injury.
- Conditions
- Lower Limb; Sprain (Strain), Lower Limb Fracture, Stroke, Multiple Sclerosis
- Trial name
- NCT05347875
- Testing
- Walking aid skills app, Breathing skills app
- Where
- 2 sites in Canada
- Volunteers
- 52 people
- Sponsor
- University of Calgary
Atrial Fibrillation, Stroke
AI-Assisted Workflow for Occult Atrial Fibrillation Detection After Ischemic Stroke: A Prospective Randomized Trial
We hypothesize that an AI-guided AF risk stratification approach, particularly when combined with intensified rhythm monitoring using wearable devices and extended ECG patches, will significantly increase AF detection rates…
- Conditions
- Atrial Fibrillation, Stroke, Artificial Intelligence
- Trial name
- AI-AFIS (NCT07540065)
- Testing
- Active Follow-up Group, Standard Follow-up Group
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- National Taiwan University Hospital
Stroke, Inflammation
Combinating Fingolimod With Alteplase Bridging With Mechanical Thrombectomy in Acute Ischemic Stroke
Proof-of concept clinical trials have indicated that the sphingosine-1-phosphate receptor modulator fingolimod may be efficacious in attenuating brain inflammation and improving clinical outcomes in patients with AIS as a single…
- Trial name
- FAMTAIS (NCT02956200)
- Testing
- Fingolimod
- Where
- China
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ischemic Stroke
Tongxinluo Capsule in Ischemic Stroke Patients（TISS)
The purpose of this study is to assess the effects in improving life self-care ability of stroke patients after taking Tongxinluo Capsule(within 72 hours after onset) versus Placebos for 90 days.
- Trial name
- NCT01919671
- Testing
- Tongxinluo capsule
- Where
- China
- Volunteers
- 2,007 people
- Sponsor
- yongjun wang
Stroke, Acute, Stroke
Yield of Implantable Cardiac Monitoring Device in Patients With Acute Ischemic Stroke.
In this prospective cohort study, the investigators aim to investigate the incidence of ICM-detected AF in unselected ischemic stroke patients and its association with anticoagulation initiation and stroke recurrence.
- Conditions
- Stroke, Acute, Stroke, Stroke, Ischemic, Atrial Fibrillation
- Trial name
- NCT05494034
- Testing
- Reveal LINQTM
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Stroke, Hemiplegia
Usability Testing of Affordable Haptic Robots for Stroke Therapy
Stroke survivors with hemiplegia will be evaluated by rehabilitation professionals and asked to perform a battery of assessments to test the viability and usability of a force-feedback robot that adapts to each individual…
- Trial name
- Theradrive (NCT02772809)
- Testing
- Haptic Robot Therapy with Games
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Pennsylvania
Stroke
TENS and Spasticity in Stroke Patients
study aims to evaluate the efficacy of high and low frequency TENS on spasticity, strength and functional status in stroke patients.
- Trial name
- NCT05075109
- Testing
- High Frequency TENS, Low Frequency TENS, Task Related Training
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Dementia, Motor Impairments
PERDOVE ANZIANI: a Prospective Cohort Study on Older Patients
This prospective observational cohort study aims at studying functional and clinical outcomes of patients (N = 329) admitted to 4 geriatric hospital facilities of the St John of God Order in Northern Italy during an index period…
- Conditions
- Dementia, Motor Impairments, Stroke, Thighbone Fractures
- Trial name
- NCT01699984
- Where
- 4 sites in Italy
- Volunteers
- 329 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Stroke, Ischemic, Thrombectomy
Prognostic Value of Isolated and Combined Score Aspects in Acute Ischemic Stroke
This study, called TARGET-ASPECT, looks at patients who had a type of stroke called acute ischemic stroke and were treated with clot-busting medicine and a procedure to remove the clot.
- Conditions
- Stroke, Ischemic, Thrombectomy, Thrombolytic Therapy, Brain Ischemia
- Trial name
- NCT07069452
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Centre Hospitalier de Gonesse
Stroke Patients With Hemiplegia or Hemiparesis in the Subacute Stage
The Effect of Combined Transcranial Pulse Current Stimulation (tPCS) and Transcutaneous Electrical Nerve Stimulation (TENS) on Lower Limb Motor Function in Subacute to Chronic Stroke Patients With Hemiplegia (COMPENSATOR-Stroke)
The goal of this study is to evaluate the effects of high frequency tPCS + TENS compared to Sham device stimulation + TENS (Control) in lower limb motor function recovery in stroke patients with hemiplegia or hemiparesis in the…
- Trial name
- COMPENSATOR (NCT06999876)
- Testing
- The AscenZ-VIII Stimulator (Investigational Medical Device)
- Where
- 2 sites in Singapore
- Volunteers
- 90 people
- Sponsor
- National University Health System, Singapore
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