Clinical trials: Strokes Thrombotic
Perinatal Stroke
Baby Brain Recovery Study
This study will be a longitudinal multiple-visit observational study, done to identify possible bioindicators of recovery and repair of motor corticospinal pathways which may be targeted by future interventions in infants with…
- Trial name
- NCT05013736
- Testing
- Magnetic Resonance Imaging, Behavioral Assessments, Non invasive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Wisconsin, Madison
Ischemic Stroke, Intracranial Atherosclerotic Disease
Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in Intracranial Atherosclerotic Disease
CATIS-ICAD is a clinical pilot study in which patients who have had a recent ischemic stroke, that is a stroke caused by a blood clot or a narrowing of the blood vessels in the brain due to the build up of plaque, will be…
- Trial name
- NCT04142125
- Testing
- Rivaroxaban 2.5 Mg Oral Tablet bid, Acetylsalicyclic acid 81 mg tablet qd
- Where
- 10 sites in Canada
- Volunteers
- 101 people
- Sponsor
- Population Health Research Institute
Ischemic Stroke, Atrial Fibrillation
Ischemia Care Biomarkers of Acute Stroke Etiology (BASE)
The proposed study will validate the clinical use of new biomarker blood tests to identify blood components that may differentiate between diverse stroke etiologies and clinical outcomes as listed below: 1.
- Conditions
- Ischemic Stroke, Atrial Fibrillation, Transient Ischemic Attacks, Transient Cerebrovascular Events
- Trial name
- BASE (NCT02014896)
- Testing
- Biomarker blood draw
- Where
- 22 sites in United States
- Volunteers
- 1,750 people
- Sponsor
- Ischemia Care LLC
Atrial Fibrillation, Stroke
Advanced Cardiac Imaging To Predict Embolic Stroke On Brain MRI: A Pilot Study
Demonstrating the pathophysiological link between Left Atrial (LA) and Left Atrial Appendage (LAA) pathology and embolic strokes in non-Atrial Fibrillation (AF) individuals represents a major advance in stroke prevention…
- Conditions
- Atrial Fibrillation, Stroke, Stroke, Cardiovascular, Vascular Cognitive Impairment
- Trial name
- NCT04769310
- Testing
- Cardiac and Brain MRI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Tulane University
Hemiparesis, Neonatal Stroke
Transcranial Magnetic Stimulation in Children With Stroke
This is a pilot study of repetitive transcranial magnetic stimulation (rTMS) to test tolerance and efficacy in children who have hemiparesis from acquired or presumed perinatal stroke.
- Conditions
- Hemiparesis, Neonatal Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- TMSCS (NCT01637129)
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Nationwide Children's Hospital
Ischemic Stroke
Anti-inflammatory and Anti-thrombotic Therapy With colcHicine and Low Dose Rivaroxaban for Major Adverse Cardiovascular Events Reduction in Ischemic Stroke
The ARCHIMEDES study (Anti-inflammatory and anti-thRombotic therapy with colCHicine and low dose rIvaroxaban for Major adverse cardiovascular Events reDuction in ischEmic Stroke) will be a randomized, double-blind, 2x2 factorial…
- Trial name
- ARCHIMEDES (NCT06396858)
- Testing
- Rivaroxaban 2.5 Mg Oral Tablet, Colchicine 0.5 MG
- Volunteers
- 4,500 people
- Sponsor
- Brazilian Clinical Research Institute
Stroke, Lacunar
The Effect of Aerobic Exercise in Patients With Lacunar Stroke
In a randomized-controlled study the effect of high-intensity training, 5 days a week at home for 12 weeks is tested in patients with lacunar stroke.
- Trial name
- HITPALS (NCT02731235)
- Testing
- High-intensity training, prophylactic stroke medication, Recommendations for lifestyle changes
- Where
- Denmark
- Volunteers
- 71 people
- Sponsor
- Herlev Hospital
Lacunar Stroke, Small Vessel Cerebrovascular Disease
Telecoached Exercise Intervention for Connectivity Enhancement in Small Vessel Disease (TELECONNECT-SVD)
The TELECONNECT-SVD study is a prospective, randomized, multicenter trial aimed at testing the efficacy of a remotely delivered exercise protocol on brain functional connectivity in patients with small vessel disease…
- Trial name
- TELECONNECT (NCT06525987)
- Testing
- Physical activity
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of L'Aquila
Dementia, Stroke
MIND Diet to Improve Cognitive Function in Mild Stroke Patients (MINDICOMS) II
A 6-month pilot randomized controlled trial designed to test the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet + usual medical care versus usual medical care on cognitive change and several…
- Conditions
- Dementia, Stroke, Cognitive Change, Cerebrovascular; Disorder, Thrombotic
- Trial name
- NCT06331247
- Testing
- General dietary advice, Localized MIND diet intervention, Routine medical care
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhejiang University
Cerebral Small Vessel Diseases, Inflammation
INflammation and Small Vessel Disease Study
A prospective observational cohort study in patients with cerebral small vessel disease deterring whether changes in systemic inflammation predict brain white matter damage measured using MRI and cognitive decline.
- Conditions
- Cerebral Small Vessel Diseases, Inflammation, Stroke
- Trial name
- INSVD (NCT05746221)
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Cambridge
End Stage Renal Disease Requiring Hemodialysis
Factor XI LICA to Reduce Events Such as Heart Attack and Stroke in Patients Whose Kidneys Are no Longer Able to Work as They Should and Require Treatment to Filter Wastes From the Blood: Focus is on the Safety of BAY2976217 and the Way the Body Absorbs, Distributes and Removes the Study Drug
Patients whose kidneys are no longer able to work as they should and require treatment to filter wastes from the blood (hemodialysis) are at high risk for blood clots that form in blood vessels (thrombosis) blocking blood flow…
- Trial name
- RE-THINc ESRD (NCT04534114)
- Testing
- Fesomersen sodium (BAY2976217)
- Where
- 69 sites in United States, Belgium and 13 more
- Volunteers
- 307 people
- Sponsor
- Bayer
Cerebrovascular Accident, Hypertension
Secondary Prevention of Small Subcortical Strokes Trial
The goal of this study is to learn if combination antiplatelet therapy (aspirin and clopidogrel) is more effective than aspirin alone for the prevention of recurrent stroke and cognitive decline, and if intensive blood pressure…
- Trial name
- SPS3 (NCT00059306)
- Testing
- aspirin, clopidogrel, Target of Blood Pressure
- Where
- 63 sites in United States, Canada and 5 more
- Volunteers
- 3,020 people
- Sponsor
- University of British Columbia
Cerebral Small Vessel Diseases, Cerebral Small Vessel Ischemic Disease
Cambridge 7 Tesla Cerebral Small Vessel Disease Study
CamSVD is jointly sponsored by the University of Cambridge and Cambridge University Hospitals NHS Foundation Trust. We aim to explore and understand the underlying arterial pathology in Cerebral Small Vessel Disease (SVD) using…
- Conditions
- Cerebral Small Vessel Diseases, Cerebral Small Vessel Ischemic Disease, Lacunar Stroke
- Trial name
- CamSVD (NCT04330222)
- Testing
- 7 Tesla Magnetic Resonance Imaging, Brief Memory and Executive Test
- Where
- United Kingdom
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Hyperhomocysteinemia, Thrombotic, Cbs-Related, Ischemic Stroke
Methylenetetrahydrofolate Reductase Deficiency in Ischemic Stroke
Adult onset epileptic seizures is rare and often associated with metabolic disorders, drugs and intracranial pathologies such as ischemia, hemorrhage or space-occupying lesions.
- Conditions
- Hyperhomocysteinemia, Thrombotic, Cbs-Related, Ischemic Stroke, Epilepsy
- Trial name
- NCT04287881
- Testing
- Methylenetetrahydrofolate reductase (MTHFR) deficiency
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul Medeniyet University
Ischemic Stroke, Thrombotic Stroke
Autonomic Neuromodulation by Transcutaneous Nerve Stimulation in Acute Ischaemic Stroke.
Autonomic modulation by transcutaneous vagal nerve stimulation in acute ischaemic stroke requiring mechanical thrombectomy: a phase IIa, sham controlled randomised trial.
- Conditions
- Ischemic Stroke, Thrombotic Stroke, Autonomic Dysfunction, Autonomic Imbalance
- Trial name
- VANS (NCT05417009)
- Testing
- trans-cutaneous auricular sensory stimulation
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Queen Mary University of London
Stroke, Ischemic, Stroke, Acute
Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke Patients
This is a randomized clinical trial to study the effect of tDCS in participants with subacute ischemic stroke, the study participants will be randomly assigned into three groups; bihemispheric, unihemispheric and sham group.
- Conditions
- Stroke, Ischemic, Stroke, Acute, Stroke, Lacunar, Hemiparesis
- Trial name
- NCT04770363
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Alexandria University
Acute Stroke, Ischemic Stroke
Rescue Intracranial Stenting in Acute Ischemic Stroke
In acute ischemic stroke caused by intracranial large vessel occlusion, rescue intracranial stenting has been recently a treatment option to achieve recanalization in patients with the failure of mechanical thrombectomy.
- Conditions
- Acute Stroke, Ischemic Stroke, Intracranial Atherosclerosis, Stent Stenosis
- Trial name
- RISIS (NCT04986774)
- Testing
- Rescue intracranial stenting
- Where
- Vietnam
- Volunteers
- 85 people
- Sponsor
- Can Tho Stroke International Services Hospital
Stroke, Atrial Fibrillation
GLORIA-AF Registry Program - Second and Third Phases
In this part of the Registry Program patients with non-valvular atrial fibrillation (AF) at risk for stroke are enrolled to characterize the target population and to collect real world data on important outcome events.
- Trial name
- NCT01468701
- Where
- 666 sites in United States, Argentina and 19 more
- Volunteers
- 37,235 people
- Sponsor
- Boehringer Ingelheim
Strokes Thrombotic
Comparison Between the Efficacy of CIMT and NDT Along With Conventional Physiotherapy Treatment on Upper Extremity Rehabilitation Among Patients of Stroke
To compare the efficacy of CIMT and NDT among stroke patients To study the phenomena of transfer of training To study relationship between the MMSE score and stroke rehabilitation
- Trial name
- CIMT (NCT06485583)
- Testing
- Constraint-induced movement therapy, Neurodevelopmental Treatment
- Where
- Pakistan
- Volunteers
- 10 people
- Sponsor
- Shalamar Institute of Health Sciences
Stroke, Atrial Fibrillation
GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)
In this part of the Registry Program patients with non-valvular atrial fibrillation (AF) at risk for stroke are enrolled to characterize the target population and to collect real world data on important outcome events.
- Trial name
- NCT01671007
- Where
- 522 sites in Austria, Belgium and 20 more
- Volunteers
- 10,471 people
- Sponsor
- Boehringer Ingelheim