Clinical trials: Strongyloidiasis
Soil-transmitted Helminthiasis, Schistosomiasis
Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders
NIDIAG is an international collaboration on integrated diagnosis-treatment platforms, funded by the European Commission (EC). NIDIAG aims to develop an improved, patient-centred system for delivering primary health care in…
- Conditions
- Soil-transmitted Helminthiasis, Schistosomiasis, Strongyloidiasis, Shigellosis
- Trial name
- NIDIAGDigest (NCT02105714)
- Testing
- Stool culturing for pathogenic bacteria, Kato-Katz technique, Baermann technique
- Where
- 7 sites in Côte d’Ivoire, Indonesia and 2 more
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Chronic Strongyloidiasis
Ivermectin Versus Albendazole for Chronic Strongyloidiasis
A prospective controlled trial to compare the efficacy and safety of 7-day albendazole, single dose ivermectin, and 2-single dose ivermectin in 72 patients with chronic strongyloidiasis will be conducted at Siriraj Hospital…
- Trial name
- NCT00765024
- Testing
- Ivermectin, Albendazole
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Mahidol University
Lymphatic Filariasis, Scabies
Better Options for Lymphatic Filariasis Treatment
The goal of this clinical trial is to learn if mass drug administration with moxidectin in combination with diethylcarbamazine, and albendazole (MoxDA) can treat lymphatic filariasis, scabies and strongyloidiasis in children and…
- Conditions
- Lymphatic Filariasis, Scabies, Strongyloidiasis
- Trial name
- BOLT (NCT07159373)
- Testing
- MoxDA - Moxidectin + Diethylcarbamzine (DEC) + Albendazole, IDA - Ivermectin + DEC + albendazole
- Where
- Fiji
- Volunteers
- 5,100 people, healthy volunteers welcome
- Sponsor
- Medicines Development for Global Health
Trachoma, Yaws
Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs )
This is a cluster randomised trial evaluating the safety of co-administering Azithromycin alongside the new IDA (Ivermectin, Diethylcarbamazine, Albendazole) combination treatment for LF.
- Conditions
- Trachoma, Yaws, Lymphatic Filariases, Scabies
- Trial name
- NCT03676140
- Testing
- Albendazole on Day 1, Ivermectin on Day 1, Diethylcarbamazine on day 1
- Where
- Papua New Guinea
- Volunteers
- 20,000 people
- Sponsor
- Lihir Medical Centre
Strongyloides Stercoralis Infection, Strongyloidiasis
Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis
Efficacy, safety and pharmacokinetics of ascending dosages of emodepside and in comparison to ivermectin against Strongyloidiasis stercoralis in adults: randomized stage II seamless adaptive controlled trials
- Trial name
- NCT06373835
- Testing
- Emodepside
- Where
- Laos
- Volunteers
- 202 people
- Sponsor
- Swiss Tropical & Public Health Institute
Malaria,Falciparum, Neglected Tropical Diseases
Adjunctive Ivermectin Mass Drug Administration for Malaria Control
This is a cluster-randomized placebo-controlled clinical trial to evaluate the additive benefit of Ivermectin (IVM) (or Placebo) mass drug administration (MDA) to dihydroartemisinin-piperaquine (DP) MDA for malaria control in a…
- Conditions
- Malaria,Falciparum, Neglected Tropical Diseases, Strongyloidiasis, Lymphatic Filariasis
- Trial name
- MATAMAL (NCT04844905)
- Testing
- Ivermectin, Dihydroartemisinin-piperaquine
- Where
- Guinea-Bissau
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Strongyloidiasis, Bone Marrow Transplant Infection
Strongyloides Stercoralis in Bone Marrow Transplant Recipients in the UK
Strongyloidiasis is a worm infection which affects more than 100 million people, mostly in Africa, Asia and Latin America, and can cause severe illness in people with reduced immunity.
- Trial name
- SSSSBMTUK (NCT04709848)
- Testing
- None - standard of care
- Volunteers
- 480 people
- Sponsor
- Imperial College Healthcare NHS Trust
Lymphatic Filarial Disease
Host Response to Infection and Treatment in Lymphatic Filarial Disease in India
Patients admitted on this protocol will have, or be suspected of having, one of the lymphatic filarial infections affecting humans.
- Trial name
- NCT00342576
- Where
- India
- Volunteers
- 1,500 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Ascariasis, Trichuriasis
Effectiveness of Combined Albendazole and Ivermectin Treatment for Intestinal Worm Infections
The aim of this study is to compare the efficacy and impact on growth of two drug treatments against intestinal worms in schoolchildren from a rural area of Guatemala.
- Conditions
- Ascariasis, Trichuriasis, Hookworm Infection, Strongyloidiasis
- Trial name
- NCT00207753
- Testing
- albendazole vs. combined albendazole/ivermectin treatment
- Where
- Guatemala
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Helminthiasis, Strongyloides Stercoralis Infection
Management of Soil-transmitted Helminthiasis and Strongyloidiasis
The general purpose of the project is to analyse soil-transmitted helminthiases (STH) in a highly endemic area in northern Argentina with a multidisciplinary approach.
- Trial name
- NCT01308268
- Testing
- Ivermectin + Albendazole
- Where
- Argentina
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Salta
Strongyloidiasis, Strongyloides Stercoralis Infection
Evaluation of Strongyloidiasis in Ecuador: a fieLd Laboratory Accuracy Study
the World Health Organization (WHO) has recently committed to promote the control of strongyloidiasis within 2030 targets for STH control programmes.
- Trial name
- ESTRELLA (NCT04999774)
- Testing
- Different diagnostic tests
- Where
- Ecuador
- Volunteers
- 781 people, healthy volunteers welcome
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
HIV Infection, Nematode Infection
Study of Patients With Strongyloides Stercoralis Infection
This study will explore faster and easier ways to detect infection with the intestinal parasite Strongyloides stercoralis and learn more about the conditions under which it causes serious disease.
- Conditions
- HIV Infection, Nematode Infection, Strongyloidiasis
- Trial name
- NCT00001245
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Strongyloides Stercoralis Infection, Strongyloidiasis
Treatment of Strongyloides Infection
The aim of this study is to evaluate the serologic response in patients with S. stercoralis infection after treatment with a regimen of two single doses of 200 µg/kg of ivermectin given 2 weeks apart versus a regimen of two…
- Trial name
- TSSI (NCT03605758)
- Testing
- Ivermectin
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Albert Einstein College of Medicine
Strongyloidiasis
Strongyloidiasis at CHRU Nancy: Evaluation of the Performance of Serological Tests and Disease-associated Characteristics
Strongyloidiasis is a disease caused by a parasite belonging to the helminth phylum: Strongyloides stercoralis. This nematode is mainly found in warm and humid regions, which favor its survival and transmission to humans.
- Trial name
- SEROANGUILLULO (NCT07296198)
- Testing
- Strongyloides serology
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Central Hospital, Nancy, France
Trichuriasis, Strongyloidiasis
Combination Therapies for Trichuris Trichiura Infection in Schoolchildren in Honduras
The goal of this Phase III clinical trial is to evaluate the efficacy, safety, and acceptability of different treatment regimens for Trichuris trichiura infection in schoolchildren aged 6 to 15 years living in La Moskitia…
- Conditions
- Trichuriasis, Strongyloidiasis, Ascariasis, Hookworm Infection
- Trial name
- AIM-T (NCT07661316)
- Testing
- Albendazole 400 mg, Albendazole Plus Ivermectin, Fixed-Dose Combination Albendazole/Ivermectin (FDC)
- Where
- Honduras
- Volunteers
- 368 people
- Sponsor
- Mundo Sano Foundation
Hiv, Hepatitis B
Delivering a Multi-disease Screening Tool to Migrant Populations
Migrants' overall health status may be improved by increasing the detection of certain infectious diseases and other conditions for which effective care is available.
- Conditions
- Hiv, Hepatitis B, Hepatitis C, Tuberculosis
- Trial name
- ISMiHealth (NCT05868005)
- Testing
- Clinical decision support system for screening of migrants using the ISMiHealth software tool.
- Where
- 2 sites in Spain
- Volunteers
- 980 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
Strongyloidiasis
Multiple Versus Single Dose of Ivermectin for the Treatment of Strongyloidiasis
Ivermectin is currently the best drug to cure strongyloidiasis, but the "standard" single dose of 200 mcg/kg is probably not enough to guarantee cure.
- Trial name
- STRONGTREAT (NCT01570504)
- Testing
- Ivermectin
- Where
- 9 sites in Italy, Spain and 1 more
- Volunteers
- 312 people
- Sponsor
- Centro per le Malattie Tropicali