Clinical trials: Study Protocol Feasibility
Mental Disorders
Reducing Stigma Among Healthcare Providers to Improve Mental Health Services
A growing number of trials have demonstrated treatment effectiveness for people with mental illness (PWMI) by non-specialist providers, such as primary care and community health workers, in low-resource settings.
- Trial name
- RESHAPE-mh (NCT02793271)
- Testing
- RESHAPE, PRIME/mhGAP
- Where
- Nepal
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Brandon A Kohrt, MD, PhD
Depression Disorders, Anxiety
Unified Protocol in Penitentiary Facilities
Emotional disorders (EDs), which include anxiety disorders, unipolar mood disorders, and other related conditions, exhibit a high prevalence within prison populations, significantly exceeding that of the general population.
- Conditions
- Depression Disorders, Anxiety, Mood Disorders, Emotional Disorder
- Trial name
- NCT07070531
- Testing
- Unified Protocol
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Physical Activity, Life Style
Cardiovascular Disease Prevention Strategies for High-risk Urban Sedentary Employees in Karachi, Pakistan
Heart diseases and other non-communicable diseases are serious health issues in countries like Pakistan. Many people who work in offices, like bank employees, sit for more than 8 hours a day.
- Conditions
- Physical Activity, Life Style, Dietary Habits, Cardiovascular Diseases
- Trial name
- m-LIfE (NCT06981247)
- Testing
- m-LIfE: mobile based lifestyle intervention for employees to increase their physical activity and promote healthy diet., Routine care arm
- Where
- Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Anterior Cruciate Ligament Reconstruction
Knee Care @Home Programme Feasibility Trial
The main goal of this trial is to determine the feasibility of a randomized controlled trial for the Knee Care at Home Programme, rather than the effectiveness, for patients recovering from anterior cruciate ligament…
- Trial name
- NCT06152380
- Testing
- Knee Care @Home Programme
- Volunteers
- 56 people
- Sponsor
- University of Évora
Infertility Assisted Reproductive Technology
The Feasibility of taVNS on Pregnancy Outcomes of Infertility Patients Undergoing IVF
To assess the feasibility of taVNS on pregnancy outcomes of infertility subjects undergoing IVF, the primary aim of this trial will focus on encompassing recruitment, compliance, and preliminary engagement outcomes.
- Trial name
- NCT06742788
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xijing Hospital
Metastatic Cancer, Pain
Percutaneous Cryoablation in Treating Patients With Painful Bone Metastases
RATIONALE: Percutaneous cryoablation may help relieve pain caused by bone metastases. PURPOSE: This clinical trial is studying the side effects and how well percutaneous cryoablation works in treating patients with painful bone…
- Conditions
- Metastatic Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00608855
- Testing
- questionnaire administration, cryosurgery, pain therapy
- Where
- 10 sites in United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Healthy Women
TMS-Induced LH Response in Healthy Women in Luteal Phase
The purpose of this research is to establish whether non-invasive Transcranial Magnetic Stimulation (TMS), can affect modulation of hormones such: Luteinizing Hormone (LH) and Follicle-stimulating hormone (FSH).
- Trial name
- NCT07363421
- Testing
- Transcranial Magnetic Stimulation Active
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The City College of New York
Pregnancy, Prolonged, Induced; Birth
Membrane Sweeping to Prevent Post-term Pregnancy: The MILO Study
Multicentre, pragmatic, parallel group, pilot randomised controlled trial with an embedded factorial design.
- Conditions
- Pregnancy, Prolonged, Induced; Birth, Pregnancy Related
- Trial name
- MILO (NCT04307199)
- Testing
- Amniotic membrane sweep
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Emotional Disorder
Feasibility of "EmoGuía" to Guide and Personalize Psychological Treatments
The present project aims at testing the feasibility of an app-based system called "EmoGuía" for routine outcome monitoring of adult patients with emotional disorders while they are administered a self-applied online…
- Trial name
- NCT05109780
- Testing
- My EMI, Emotional Well-being + self-applied online transdiagnostic treatment
- Volunteers
- 30 people
- Sponsor
- Universitat Jaume I
Reproducibility of Results
Reproducibility of Brain MRI
The aim of this study is to assess the reproducibility over time of functional and structural magnetic resonance imaging, as well as specific biomarkers in plasma in healthy volunteers before and after a two-hour rest.
- Trial name
- DANA0 (NCT03876236)
- Where
- 2 sites in Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Neurocognitive Decline, Feasibility
Comparison Between Analog Neurocognitive Tests Conducted by a Trained Test Leader Versus Self-administered Digital Tests
The study has a randomized crossover design including qualitative interviews of the participant's test experiences. Healthy participants, ≥60 years are eligible to participate in the study.
- Conditions
- Neurocognitive Decline, Feasibility, Costs, Interviews
- Trial name
- PICASU-Eq (NCT05253612)
- Testing
- Analog testing conducted by a trained test leader using, ISPOCD test battery, self-administered Mindmore digital cognitive screening battery
- Where
- Sweden
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
A Bite of ACT' (BOA) Acceptance and Commitment Therapy Online Psychoeducation Course, A Wait-list Control
Study Protocol for a Feasibility Study of a Novel ACT-based eHealth Psychoeducational Intervention for Students With Mental Distress
Here we propose a protocol for assessing the feasibility and acceptability of a randomised controlled trial (RCT) of an online transdiagnostic psychoeducational intervention called 'A Bite of ACT' (BOA) compared to a waitlist…
- Trial name
- NCT03810131
- Testing
- 'A Bite of ACT' (BOA)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Swansea University
Testing Protocol With Healthy Individuals for Feasibility
Parent-Adolescent Training on Neurofeedback and Synchrony
The study will test a real-time functional magnetic resonance imaging (fMRI) hyperscanning neurofeedback protocol for feasibility with ten mothers and their psychiatrically healthy adolescent daughters, with the eventual goal to…
- Trial name
- NCT03929263
- Testing
- Real-time fMRI neurofeedback
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Stroke, Parkinson Disease
Feasibility of Two New Software Modules for the Rehabilitation of Patients With Neuromuscular Upper Limb Impairments
Introduction: In the recent past, medical training systems using virtual reality (VR) have been introduced to neurorehabilitation to train motor function deficits in patients.
- Conditions
- Stroke, Parkinson Disease, Traumatic Brain Injury, Guillain-Barre Syndrome
- Trial name
- NCT03268304
- Testing
- VR-based training including AO and MI
- Sponsor
- Reha Rheinfelden
Stroke
Feasibility and Safety of In-bed Self-exercise in Patients With Subacute Stroke
The goal of this to investigate the feasibility and safety of in-bed self-exercises based on EMG-sensor feedback in subacute stroke patients. The main question is feasibility and safety.
- Trial name
- NCT05820815
- Testing
- in-bed self-exercises based on EMG-sensor feedback intervention
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
Functional Movement Disorder
Digital Telerehabilitation in Functional Motor Disorders
Functional motor disorders (FMDs) are a broad spectrum of functional neurological disorders, including abnormal gait/balance disorders.
- Trial name
- NCT06274281
- Testing
- Digital Telerehabilitation, Usual care
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- Universita di Verona
Post Traumatic Stress Symptoms, Quality of Life (QOL)
A Feasibility Trial of Eye Movement Desensitization and Reprocessing Therapy- Integrative Treatment Group Protocol for Ongoing Traumatic Stress In Road Traffic Accident Survivors for Reduction of Post-traumatic Stress Symptoms
Road traffic accidents (RTAs) are a significant public health concern globally, accounting for a substantial proportion of morbidity and mortality.
- Conditions
- Post Traumatic Stress Symptoms, Quality of Life (QOL), Stress
- Trial name
- EMDR-IGTP-OTS (NCT07027930)
- Testing
- Eye movement desensitization and reprocessing therapy integrative group treatment protocol for Ongoing traumatic stress
- Where
- Pakistan
- Volunteers
- 35 people
- Sponsor
- University of the Punjab
Stimulants Use Disorder
Deep Transcranial Magnetic Stimulation for Stimulants Use Disorder
The purpose of the study is to explore the Feasibility, Tolerability and Safety of the H7-Coil deep Transcranial Magnetic Stimulation for Subjects with Stimulants Use Disorder (SUD).
- Trial name
- NCT05274828
- Testing
- H7-Coil Deep TMS for CUD
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Carcinoma, Non-Small-Cell Lung
Feasibility of an Acute Physical Exercise Before Treatment Infusion for Metastatic Lung Cancer Patients
Because of metastatic Non-Small Cell Lung Cancer (mNSCLC) and its treatments, patients suffer from numerous symptoms such as dyspnea, muscle atrophy, pain, fatigue, loss of appetite, altered physical condition and lung function…
- Trial name
- ERICA (NCT04676009)
- Testing
- Exercise arm :
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Centre Leon Berard
Invasive Candidiasis
Pilot Feasibility Study With Patients Who Are at High Risk For Developing Invasive Candidiasis in a Critical Care Setting (MK-0991-067)
This is a pilot feasibility study that investigates antifungal therapy with caspofungin in patients at high-risk for developing invasive candidiasis in a critical care setting.
- Trial name
- NCT01045798
- Testing
- Caspofungin acetate
- Volunteers
- 15 people
- Sponsor
- Merck Sharp & Dohme LLC