Clinical trials: Study Protocol Feasibility, open to volunteers
Hemolysis
Feasibility Performance Study of ABL90 FLEX PLUS HEM
This feasibility performance study evaluates the ABL90 FLEX PLUS HEM device for its analytical performance in a clinical setting. The study aims to evaluate the performance of the hemolysis detection feature.
- Trial name
- ABL90FLEXHEM (NCT07345091)
- Testing
- The purpose of this study is to investigate the performance of the hemolysis detection function on the ABL90 FLEX PLUS HEM using arterial or venous whole blood
- Where
- Denmark
- Volunteers
- 95 people
- Sponsor
- Radiometer Medical ApS
Pain After Surgery, Anxiety After Surgery
Using Mindfulness in an Enhanced Recovery After Surgery Protocol to Support Recovery After Colorectal Surgery
This study teaches participants who are having colorectal surgery how to use mindfulness to feel calmer and manage pain better. Participants will be randomized (like a flip of a coin) into one of two groups: Mindfulness…
- Trial name
- NCT07026786
- Testing
- Mindfulness Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University Hospitals Cleveland Medical Center
Anxiety, Post Traumatic Stress Disorder
Improving Mental Health in Forcibly Displaced Populations
This project aims to improve mental health support for Venezuelan migrants living in Lima, Peru, who often face challenges like anxiety, depression, and post-traumatic stress disorder (PTSD).
- Conditions
- Anxiety, Post Traumatic Stress Disorder, Depression
- Trial name
- NCT06635486
- Testing
- Adapted cognitive-behavioral (CBT) intervention
- Where
- Peru
- Volunteers
- 90 people
- Sponsor
- Boston Medical Center
Suicidal Ideation
Stratified-Care School-Based Intervention for Adolescent Suicidal Ideation
Background. Suicidal ideation and depressive symptoms are highly prevalent among adolescents, with suicide representing a leading cause of death in this age group worldwide.
- Trial name
- NCT07063914
- Testing
- Reframe-IT and CARIBOU
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Universidad de los Andes, Chile
Spinal Cord Injuries, Respiratory Failure
High Flow Oxygen Therapy After Spinal Cord Injury
The goal of this feasibility study is to learn about the ability to use a different form of oxygen therapy (known as high flow oxygen therapy) in patients who have a spinal cord injury in the upper back or neck.
- Trial name
- NCT06244160
- Testing
- High flow oxygen therapy
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Cardiff and Vale University Health Board
Breast Cancer Female
Safety, Feasibility, and Outcomes of Early Rehabilitation After Breast Cancer Surgery
Breast cancer is one of the most common tumours in women. Advances in diagnosis and treatment have increased survival, but many women experience functional sequelae after breast and/or axillary surgery, including pain, reduced…
- Trial name
- EMOVE-BCS (NCT07651696)
- Testing
- Early Postoperative Rehabilitation Protocol
- Volunteers
- 110 people
- Sponsor
- Marta Aguilar-Rodriguez
Liver Failure
TLI- and ATG-Enabled Minimization Protocol in Liver Transplantation
The unmet medical need in solid organ transplantation is to eliminate the lifelong requirement of powerful immune suppression drug combinations with their attendant side effects, and to prevent immune mediated rejection of the…
- Trial name
- TEMPO-LT (NCT07634562)
- Testing
- Anti-Thymocyte Globulin, ATG (Rabbit), Total lymphoid irradiation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
ADHD - Attention Deficit Disorder With Hyperactivity
External Trigeminal Nerve Stimulation for Attention Deficit Hyperactivity Disorder - Feasibility Trial
The investigators will assess the use of the Monarch eTNS device as a non-pharmacological treatment for patients aged 7 to 17 years with ADHD. The investigators will compare the eTNS device to a sham device.
- Trial name
- eTNS4ADHD (NCT06655610)
- Testing
- External Trigeminal Nerve Stimulation
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Breast Cancer
Implementing Polygenic Risk Scores for Breast Cancer Prevention: a Feasibility Study
This single-arm interventional feasibility study will evaluate whether integrating polygenic risk scores (PRS) into the CanRisk model can improve breast cancer risk prediction and personalized prevention in women at risk of…
- Trial name
- MIG (NCT06922708)
- Testing
- Clinical pathway for breast cancer prevention based on PRS-integrated CanRisk assessment
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Autistic Spectrum Disorder, Anxiety Disorders
Feasibility Study of UP-A-AST Parent Group for Adolescents With Autism and Co-occurring Anxiety/Depression
Autism spectrum disorder (ASD) is associated with high rates of psychiatric comorbidity, particularly anxiety and depressive disorders, which contribute to significant impairment for affected youth and their families.
- Conditions
- Autistic Spectrum Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT07637799
- Testing
- Unified Protocol-Adolescent Autism Parent Group (UP-A-AST)
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Sahlgrenska University Hospital
Emotional Disorders
The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Older Adults: a Feasibility Study
Psychological treatment is less likely to be offered in an older population. In order to adapt treatment effectively for this population, more research is necessary.
- Trial name
- UPS (NCT06777693)
- Testing
- Unified Protocol
- Where
- Norway
- Volunteers
- 24 people
- Sponsor
- NKS Olaviken Gerontopsychiatric Hospital
Heart Failure, Self-care
mHealth Intervention to Support Self-care During the Hospital to Home Transition in Individuals With Heart Failure
This study is a pilot randomized controlled trial designed to evaluate the feasibility, acceptability, usability, and preliminary efficacy of a mobile health (mHealth) educational self-management intervention for individuals with…
- Conditions
- Heart Failure, Self-care, Transitional Care
- Trial name
- HF-mHealth (NCT07478081)
- Testing
- mHealth Educational Self-Management Application, Usual transitional care
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Universidad de la Sabana
Traumatic Brain Injury, Cognitive Dysfunction
Feasibility, Safety, and Preliminary Efficacy of Median Nerve Stimulation for Cognitive Dysfunction in Patients With Acute Traumatic Brain Injury
Currently, the treatment of cognitive dysfunction after acute TBI remains a challenge, and novel therapeutic methods are urgently needed.
- Trial name
- MARS-TBI (NCT07413562)
- Testing
- Median nerve stimulation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Tiantan Hospital
Appendectomy, Laparoscopic, Acute Appendicitis
Feasibility and Safety of a Pediatric ERAS Protocol for Laparoscopic Appendectomy
Acute appendicitis is the most common surgical emergency in children. Despite the widespread adoption of laparoscopic appendectomy, postoperative care still varies widely between institutions, with prolonged fasting, opioid-based…
- Conditions
- Appendectomy, Laparoscopic, Acute Appendicitis, Pediatric Surgery, ERAS
- Trial name
- NCT07643285
- Testing
- Comprehensive 20-Item Pediatric ERAS Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ahmet Burak Doğan, MD
Cancer
Testing the Feasibility of Balance, Activity, Quality of Life and Social Equity (BALanSE): An Activity- and Resource-oriented Rehabilitation and Palliative Care Intervention for People With Cancer
Research shows that people living with cancer often struggle to manage their energy and resources in a way that allows them to take part in the everyday activities that matter most to them.
- Trial name
- BALanSE (NCT07557043)
- Testing
- BALanSE intervention
- Volunteers
- 30 people
- Sponsor
- University of Southern Denmark
Delirium - Postoperative
Effectiveness of Electroencephalography Guided Anesthesia
This study will use brain wave information, known as electroencephalography (EEG), to help guide anesthesia delivery during surgery.
- Trial name
- EEG Anesthesia (NCT07567729)
- Testing
- EEG-guided anesthesia training program for anesthesia providers, EEG-Guided Intervention
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Stanford University
Emotional Disorders, Anxiety
Blended Unified Protocol for Emotional Disorders in Primary Care
The goal of this clinical trial is to learn if a "blended" therapy format (combining face-to-face therapy sessions with a smartphone app) works to treat emotional disorders, such as depression and anxiety, in adults.
- Conditions
- Emotional Disorders, Anxiety, Depression
- Trial name
- NCT07432906
- Testing
- Unified Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Aydin Adnan Menderes University
Stroke
YOGA-FIT: Protocol for a Crossover Trial Investigating the Feasibility and Impact of Yoga for People With Stroke
The primary objective of this mixed-methods pilot crossover study is to determine the feasibility (participant satisfaction, recruitment rate, retention, participant and assessor burden, adherence, equipment and technology…
- Trial name
- YOGA-FIT (NCT07143162)
- Testing
- LoveYourBrain Yoga
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Nova Scotia Health Authority
Infertility Assisted Reproductive Technology
fertiShare Evaluation
Sharing bad news (SBN) is a daily challenge for fertility staff and patients. Bad news happens at all stages of fertility care and includes e.g., diagnosing infertility, reporting unexpected, repeated, or definitive treatment…
- Trial name
- NCT06587360
- Testing
- fertiShare intervention - sharing bad news eLearning course, fertiShare control - basic communication skills eLearning course
- Where
- 5 sites in United Kingdom
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Cardiff University
Study Protocol Feasibility, Non Clinical Anxiety
Effects of Darkness Retreat: a Pilot Study
The primary goal of this pilot study is to test the feasibility and safety of a research protocol for a voluntary darkness retreat.
- Conditions
- Study Protocol Feasibility, Non Clinical Anxiety, Non Clinical Worry, Non Clinical Rumination
- Trial name
- NCT07429617
- Testing
- Darkness Retreat - Several Days of Seclusion in Complete Darkness
- Where
- 2 sites in Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw