Clinical trials: Study Protocol Feasibility
Chronic Condition, Chronic Conditions, Multiple
Group-based [ADAPT] Versus One-to-one [Usual] Occupational Therapy: A Pilot and Feasibility Study
Background: The number of people living with chronic conditions limiting the ability to perform activities of daily living (ADL) tasks is increasing.
- Trial name
- Go:OT (NCT05775653)
- Testing
- ADAPT program, UOT
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Parker Research Institute
High Risk of Significant Coronary Artery Disease
Cardiac GSI Feasibility Study
The recently introduced Computed tomography (CT) scanner, Discovery CT750 HD (GE Healthcare, Milwaukee), incorporates a battery of innovations aimed at improving diagnostic image quality, evaluating perfusion and assessing for…
- Trial name
- NCT01816750
- Testing
- Cardiac GSI
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University Hospital Plymouth NHS Trust
Lymphoblastic Leukemia, Lymphoblastic Leukemia in Children
CD19-Directed Chimeric Antigen Receptor (CAR) T-Cell Therapy for Relapsed/Refractory B-Lineage Leukaemia / Lymphoma - A Feasibility Protocol
The purpose of this study is to describe feasibility of delivering point-of-care manufactured CD19-directed CAR T-cell therapy to patients with relapsed/ refractory B-lineage leukaemia/ lymphoma.
- Conditions
- Lymphoblastic Leukemia, Lymphoblastic Leukemia in Children, Lymphoblastic Leukemia, Acute Adult, B-cell Acute Lymphoblastic Leukemia
- Trial name
- NCT05648019
- Testing
- Anti-CD19 CAR T-cells
- Where
- 2 sites in Singapore
- Volunteers
- 40 people
- Sponsor
- KK Women's and Children's Hospital
People With Subjective Cognitive Impairement (SCI)
Physical Activity Component of the Greek Interventional Geriatric Study to Prevent Cognitive Impairment and Disability (GINGER)
The Greek Interventional Geriatric Study to Prevent Cognitive Impairment and Disability (GINGER) is a six-month multimodal, multicenter study aimed at people with Subjective Cognitive Impairement (SCI).
- Trial name
- GINGER (NCT06528379)
- Testing
- Physical Activity
- Where
- 2 sites in Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Patras
Colorectal Cancer
CITRuS Stage 1; Feasibility
Bowel cancer is the third most common cancer occurring in the UK. Treatment usually involves surgery, often with chemotherapy or radiotherapy.
- Trial name
- CITRuS1 (NCT04697394)
- Where
- United Kingdom
- Volunteers
- 380 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Cystic Fibrosis, Fibrosis
The Alfred Step Test Exercise Protocol (A-STEP), for Adults With Cystic Fibrosis.
Exercise testing has become clinically important in the management and ongoing evaluation of patients with Cystic Fibrosis (CF) with higher rates of exercise tolerance and participation previously linked to lower mortality risk…
- Conditions
- Cystic Fibrosis, Fibrosis, Lung Diseases, Respiratory Diseases
- Trial name
- A-STEP (NCT02717650)
- Testing
- A-STEP, A-STEP (New Protocol), Comparator: CPET cycle ergometer (Gold Standard)
- Where
- Australia
- Volunteers
- 7 people
- Sponsor
- The Alfred
Aging, Fall
ABLE (Arts-Based Exercise Enhancing LongEvity)
Older adults who are referred to home care physiotherapy often only get to see the physiotherapist three to five times and are expected to continue exercising on their own.
- Conditions
- Aging, Fall, Muscle Weakness, Mobility Limitation
- Trial name
- NCT03675490
- Testing
- ABLE - exercise with interactive technology
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- McMaster University
Dupuytren&Amp;#39;s Contracture, Dupuytren&Amp;#39;s Fasciectomy
Preoperative Serial Casting, Education, and Therapy for Dupuytren's Contracture
We are running a small study to test whether a special type of therapy - including casting, stretching, and massage - might help improve recovery after Dupuytren's Fasciectomy.
- Conditions
- Dupuytren&Amp;#39;s Contracture, Dupuytren&Amp;#39;s Fasciectomy, Dupuytren&Amp;#39;s Disease
- Trial name
- PRESCET (NCT07024576)
- Testing
- Preoperative casting intervention
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Bournemouth University
Pregnancy, High Risk
An Adapted Mindfulness-based Stress Reduction Program for Psycho-socially Vulnerable Pregnant Women.
This protocol is for a feasibility study of an adapted mindfulness-based stress reduction (MBSR) program for high-risk pregnant women.
- Trial name
- NCT04571190
- Testing
- Prenatal MBSR
- Where
- Denmark
- Volunteers
- 73 people
- Sponsor
- University of Aarhus
Older Adults, Participation
ASSIST 1.0 an Intervention Program Addressing Reablement Services
Reablement holds a potential to become a new rehabilitation model and has been implemented in some western countries including Norway and Denmark.
- Trial name
- NCT03505619
- Testing
- ASSIST 1.0
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet
Critically Ill
Enhanced Protein-Energy Provision Via the Enteral Route in Critically Ill Patients
The purpose of this pilot study is to assess the feasibility, acceptability, and safety of a new feeding protocol, "The Enhanced Protein-Energy Provision via the Enteral Route in Critically Ill Patients: The PEP uP protocol."
- Trial name
- PEP-uP (NCT01102348)
- Testing
- PEP-uP Protocol
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Daren K. Heyland
Eating Disorders
tDCS and Emotional Eating
This research investigates the feasibility of undertaking a large, randomised control trial of transcranial direct current stimulation (tDCS) as a treatment modality for managing food cravings and emotional eating.
- Trial name
- NCT06488287
- Testing
- Transcranial direct current stimulation (brain stimulation)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Nottingham
Fibromyalgia
PRPP Model for Evaluation the Effect of Non-pharmaceutical Therapies
To assess the application of partially randomized patient preference (PRPP) trial model which concerns the patients' preference on evaluation the therapeutic effect of non-pharmaceutical therapy, and to observe the therapeutic…
- Trial name
- NCT01869712
- Testing
- Cupping therapy, Acupuncture
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Beijing University of Chinese Medicine
Health Literacy, Health Related Quality of Life
Feasibility of a Life Coping Program: A Study Protocol
The goal of this observational study is to evaluate the feasibility of the intervention Life Coping Program in children and adolescents 8-16 years of age.
- Conditions
- Health Literacy, Health Related Quality of Life, Physical Activity, Pediatric ALL
- Trial name
- LifeCOPE (NCT06709248)
- Testing
- Life Coping Program
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Haukeland University Hospital
Chronic Illnesses, Multiple
FLIGHT Study for Childhood Chronic Illness
The FLIGHT study is an open-label, single-arm, pilot and feasibility study of a personalized and multimodality intervention focusing upon modifiable lifestyle factors, environmental modifications, and transdisciplinary clinical…
- Trial name
- NCT06377384
- Testing
- FLIGHT Intervention
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Documenting Hope Project
Weaning From Mechanical Ventilation
Nurses-driven, Capnography-guided Protocol Weaning From the Mechanical Ventilation at Bedside: A Feasibility Study
Background: Prolonged mechanical ventilation (MV) exposes patients to increased risk of infection and mortality. A weaning protocol (WP) reduces the duration of MV.
- Trial name
- NURSES-WEAN (NCT05000034)
- Testing
- Weaning protocol
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims
Moderate Acute Malnutrition (MAM)
Development, Feasibility and Acceptability of Recipes for Locally Available, Specially Formulated Foods for the Management of Moderate Acute Malnutrition in Niger (Related to NCT06382857 Protocol)
The study consisted of two phases. Phase 1 was a recipe development phase, which aimed to identify recipes that meet ≥80% of the recommended nutrient profile for Specially Formulated Foods (SFF) used in the standard management of…
- Trial name
- LAF (NCT07506213)
- Testing
- Locally Available Food
- Where
- Niger
- Volunteers
- 30 people
- Sponsor
- Epicentre
Communication Barriers, Eye-tracking Technology
Eye-Tracking Communication Tool for Non-verbal ICU Patients
The objectives of this clinical trial are to explore the feasibility of the eye-tracking communication tool in alleviating communication barriers among non-verbal ICU patients.
- Conditions
- Communication Barriers, Eye-tracking Technology, ICU Patients
- Trial name
- NCT07205419
- Testing
- Eye-Tracking communication tool, Conventional Techniques
- Volunteers
- 40 people
- Sponsor
- Shanghai Zhongshan Hospital
Pancreatic Neoplasms
Safety and Feasibility Study of Enhanced Recovery in Pancreaticoduodenectomy
The purpose of this study is to assess the adherence to an enhanced recovery after surgery (ERAS) pathway and the impact of the ERAS protocol on postoperative short-term outcome in patients undergoing pancreaticoduodenectomy (PD).
- Trial name
- NCT01759706
- Testing
- Enhanced recovery after surgery protocol, Standard perioperative care, PONV prophylaxis with Ondansetron + Dexamethasone
- Where
- Italy
- Volunteers
- 123 people
- Sponsor
- Università Vita-Salute San Raffaele
Critical Illness
Feasibility Study on Implementing Consultation-based High-quality Palliative Care Services in Intensive Care Units
Critically ill patients in intensive care units (ICUs) receive life-sustaining treatments aimed at restoring or maintaining organ function.
- Trial name
- NCT06490835
- Testing
- High-quality palliative care through consultation-based palliative care services in the ICU
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital