Clinical trials: Study Protocol Feasibility
Infertility
New Ovarian Stimulation With Random Start, Use of Progestin Protocol for Oocyte Donors
Oocyte donation is a cumbersome and demanding procedure, involving an injectable hormonal treatment for an average duration of 12 days, according to the protocols, 1 to several daily injections.
- Trial name
- RANDOS (NCT03895099)
- Testing
- Desogestrel early follicular phase, Desogestrel medium follicular phase, Desogestrel ovulatory phase
- Where
- 4 sites in France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Acute Myeloid Leukaemia
Leukemia Adapted Protocol
In resource-constrained settings such as Malawi, survival rates for pediatric acute myeloid leukemia (AML) are dismally low compared to high-resource environments.
- Trial name
- LEAP (NCT06928909)
- Testing
- Intensity-adapted pediatric acute myeloid treatment guidelines
- Where
- Malawi
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
Chronic Obstructive Pulmonary Disease
Evaluating the Feasibility, Acceptability and Pre Testing the Impact of a Self-management and Tele Monitoring Program for COPD Patients in Lebanon
Chronic obstructive pulmonary disease (COPD) has a significant impact on quality of life and is costly to the health care system.
- Trial name
- NCT04196699
- Testing
- self-management program
- Volunteers
- 30 people
- Sponsor
- University of Paris 13
Invasive Candidiasis
Pilot Feasibility Study With Patients Who Are at High Risk For Developing Invasive Candidiasis in a Critical Care Setting (MK-0991-067)
This is a pilot feasibility study that investigates antifungal therapy with caspofungin in patients at high-risk for developing invasive candidiasis in a critical care setting.
- Trial name
- NCT01045798
- Testing
- Caspofungin acetate
- Volunteers
- 15 people
- Sponsor
- Merck Sharp & Dohme LLC
Anxiety Disorders
Emotion Detectives In-Out: Feasibility and Efficacy of a Blended Version of the Unified Protocol for Children
The goal of this clinical trial is to test the efficacy of a blended format (i.e., a combination of face-to-face and online sessions into one integrated treatment protocol) of the Unified Protocol for Transdiagnostic Treatment of…
- Trial name
- NCT05747131
- Testing
- Emotion Detectives In-Out, Coping Cat
- Where
- 2 sites in Portugal
- Volunteers
- 180 people
- Sponsor
- University of Coimbra
Cancer
RAW Study Version 3.4
The purpose of this study is to investigate the feasibility of carrying out a full scale randomised controlled trial to compare the effects of giving additional information versus no additional information to patients prior to…
- Trial name
- NCT00280722
- Testing
- patient information leaflet
- Where
- United Kingdom
- Sponsor
- Oxford University Hospitals NHS Trust
Being Referred for Child Protection Services
Evaluating the Mentalization-based Treatment Lighthouse Parenting Programme: Protocol of a Feasibility and Acceptability Quasi-Experimental Study
The goal of this study is to learn whether it is practical and acceptable to deliver the Lighthouse Parenting Programme and to carry out the planned research procedures with caregivers involved with Child Protection Services.
- Trial name
- NCT07448870
- Testing
- Lighthouse Parenting Programme, Treatment-as-usual (TAU)
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Universidade do Porto
Bipolar Disorder, Depressed
Interpersonal and Social Rhythm Therapy Enter the Brief Title for Protocol IRB 09-003781>
In patients with bipolar disorder referred for psychotherapy, is interpersonal and social rhythm therapy delivered in a group psychotherapy format over 2-3 weeks feasible? This project will help determine if interpersonal social…
- Trial name
- IPSRT (NCT01037283)
- Testing
- Interpersonal and Social Rhythm Therapy
- Volunteers
- 9 people
- Sponsor
- Mayo Clinic
Autistic Spectrum Disorder, Anxiety Disorders
Feasibility Study of UP-A-AST Parent Group for Adolescents With Autism and Co-occurring Anxiety/Depression
Autism spectrum disorder (ASD) is associated with high rates of psychiatric comorbidity, particularly anxiety and depressive disorders, which contribute to significant impairment for affected youth and their families.
- Conditions
- Autistic Spectrum Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT07637799
- Testing
- Unified Protocol-Adolescent Autism Parent Group (UP-A-AST)
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Sahlgrenska University Hospital
Feasibility Studies
The Aim of This Study is to Assess the Feasibility of the Study Protocol and the Acceptability of the Mobile Application-Based Intervention. The Results Will Guide the Design and Evaluation of a Definitive, Larger-scale Study to Further Examine the Efficacy of the Refined Intervention.
This study is a pilot study for a larger future research project aimed at examining the effects of patient education delivered via a mobile application on patients' self-reported receipt of information in relation to their…
- Trial name
- NCT07589803
- Testing
- Digital patient education mobile application., Standard Care (in control arm)
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Coxa, Hospital for Joint Replacement
Low Back Pain
Evaluating the Impact of a Champion on Implementation of the Back Skills Training (BeST) Program in Canada
There is global recognition in clinical guidelines and governing bodies that low back pain (LBP) should be managed with a biopsychosocial approach.
- Trial name
- NCT04377529
- Testing
- Local Champion
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Spinal Cord Injuries, Respiratory Failure
High Flow Oxygen Therapy After Spinal Cord Injury
The goal of this feasibility study is to learn about the ability to use a different form of oxygen therapy (known as high flow oxygen therapy) in patients who have a spinal cord injury in the upper back or neck.
- Trial name
- NCT06244160
- Testing
- High flow oxygen therapy
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Cardiff and Vale University Health Board
Borderline Personality Disorder (BPD), Avoidant Personality Disorders
Physical Activity in the Management of Personality Disorders
The PANDA trial is studying whether two types of physical activity - a walking program and supervised karate training - are safe, acceptable, and possible for adults with certain personality disorders.
- Trial name
- PANDA (NCT07341438)
- Testing
- Karate, Pedometer-based walking, Treatment as usual (TAU)
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Julie Midtgaard
HIV Prevention and Care
Lafiya HIV Self-testing Study Protocol
The study aims to address low testing and related issues such as stigma, low-risk perception, and concerns about confidentiality affecting testing.
- Trial name
- NCT06238323
- Testing
- LAFIYA
- Where
- Ghana
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Low Back Pain
Feasibility and Effect of a Multidisciplinary Telematics Approach for Chronic Non-specific Low Back Pain: a Randomized, Open-label, Controlled, Pilot Clinical Trial. Study Protocol
Low back pain is a challenging condition, with a lifetime prevalence of up to 84%. The estimated prevalence of chronic non-specific low back pain is of approximately 23%.
- Trial name
- NCT05093543
- Testing
- physical rehabilitation/physiotherapy and psychosocial group sessions
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Universitari de Bellvitge
Myocardial Infarction
Feasibility and Security of a Rapid Rule-out and rule-in Troponin Protocol in the Management of NSTEMI in an Emergency Departement
Management of NSTEMI in emergency departements represent 10% of the global activity. Since the the last European Society of Cardiology recommendation the use of an 1 hour rule-in and rule-out protocol is recommended combined with…
- Trial name
- ICTUS (NCT03668587)
- Testing
- Troponin Protocol
- Where
- France
- Volunteers
- 1,099 people
- Sponsor
- Nantes University Hospital
Skin Laxity
Feasibility Study: Heavy Water Tissue Labeling Protocol
Enrolled subjects undergo tissue labeling to evaluate the rate of collagen synthesis in tissue treated with the Ulthera® System compared to control tissue.
- Trial name
- NCT01708525
- Testing
- Ulthera® System Treatment, Heavy Water
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Multiple Myeloma
The Feasibility and Effects of Exercise on Patients Suffering From Multiple Myeloma
Multiple myeloma is the second most common haematological cancer with a cancer incidence of around 500 new cases in Austria per year .
- Trial name
- NCT04300335
- Testing
- Individual Exercise, Group Exercise
- Where
- Austria
- Volunteers
- 45 people
- Sponsor
- Medical University of Vienna
Hip Osteoarthritis
Feasibility of the Hip Instructional Prehabilitation Program for Enhanced Recovery (HIPPER)
Osteoarthritis (OA), leading to hip replacement, is a leading contributor to global mobility impairment. Given the boom in the older demographic it is not surprising that there is an 11% increased demand for replacement every 5…
- Trial name
- HIPPER (NCT02969512)
- Testing
- HIPPER, OASIS Online Educational Webinars
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- University of British Columbia
Alcohol Use Disorder, Alcohol Abuse
Internet-delivered Cognitive Behavior Therapy for Problematic Alcohol Use in a Working Life Setting
Internet-based cognitive behavioral treatment (ICBT) for mental health issues has been successfully implemented in routine health care and research indicates that ICBT can also be applied to decrease problematic alcohol use in…
- Trial name
- Simba (NCT06774716)
- Testing
- Internet-based cognitive behavioural treatment and relapse prevention, Face-to-face cognitive behavioural treatment or short-term psycodynamic therapy with relapse prevention
- Where
- Sweden
- Volunteers
- 38 people
- Sponsor
- Stockholm University