Clinical trials: Study Protocol Feasibility, open to volunteers
ADHD - Attention Deficit Disorder With Hyperactivity
External Trigeminal Nerve Stimulation for Attention Deficit Hyperactivity Disorder - Feasibility Trial
The investigators will assess the use of the Monarch eTNS device as a non-pharmacological treatment for patients aged 7 to 17 years with ADHD. The investigators will compare the eTNS device to a sham device.
- Trial name
- eTNS4ADHD (NCT06655610)
- Testing
- External Trigeminal Nerve Stimulation
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Rotator Cuff-related Shoulder Pain, Shoulder Osteoarthritis
Could a Feedback Device Help Manage Work-related Shoulder Disorders?
Work-related shoulder pain is a common problem with significant socio-economic repercussions. The impact of these disorders on workers is considerable, particularly in terms of pain, disability and reduced quality of life.
- Conditions
- Rotator Cuff-related Shoulder Pain, Shoulder Osteoarthritis, Rheumatoid Arthritis (RA)
- Trial name
- NCT06693479
- Testing
- Shoulder watch load (SWL) feedback, Education
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Laval University
Traumatic Brain Injury, Cognitive Dysfunction
Feasibility, Safety, and Preliminary Efficacy of Median Nerve Stimulation for Cognitive Dysfunction in Patients With Acute Traumatic Brain Injury
Currently, the treatment of cognitive dysfunction after acute TBI remains a challenge, and novel therapeutic methods are urgently needed.
- Trial name
- MARS-TBI (NCT07413562)
- Testing
- Median nerve stimulation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Tiantan Hospital
Internalizing Disorders, Substance Use Disorders
Family Support Protocol for Adolescent Internalizing Disorders
This R34 will develop and test an adjunctive treatment protocol for addressing co-occurring internalizing disorders among adolescents enrolled in usual care for substance use problems.
- Trial name
- Fam-AID (NCT06413979)
- Testing
- Family Support Protocol for Adolescent Internalizing Disorders (Fam-AID)
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- The National Center on Addiction and Substance Abuse at Columbia University
Dupuytren&Amp;#39;s Contracture, Dupuytren&Amp;#39;s Fasciectomy
Preoperative Serial Casting, Education, and Therapy for Dupuytren's Contracture
We are running a small study to test whether a special type of therapy - including casting, stretching, and massage - might help improve recovery after Dupuytren's Fasciectomy.
- Conditions
- Dupuytren&Amp;#39;s Contracture, Dupuytren&Amp;#39;s Fasciectomy, Dupuytren&Amp;#39;s Disease
- Trial name
- PRESCET (NCT07024576)
- Testing
- Preoperative casting intervention
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Bournemouth University
Infertility Assisted Reproductive Technology
The Feasibility of taVNS on Pregnancy Outcomes of Infertility Patients Undergoing IVF
To assess the feasibility of taVNS on pregnancy outcomes of infertility subjects undergoing IVF, the primary aim of this trial will focus on encompassing recruitment, compliance, and preliminary engagement outcomes.
- Trial name
- NCT06742788
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xijing Hospital
Physical Activity, Life Style
Cardiovascular Disease Prevention Strategies for High-risk Urban Sedentary Employees in Karachi, Pakistan
Heart diseases and other non-communicable diseases are serious health issues in countries like Pakistan. Many people who work in offices, like bank employees, sit for more than 8 hours a day.
- Conditions
- Physical Activity, Life Style, Dietary Habits, Cardiovascular Diseases
- Trial name
- m-LIfE (NCT06981247)
- Testing
- m-LIfE: mobile based lifestyle intervention for employees to increase their physical activity and promote healthy diet., Routine care arm
- Where
- Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Hand Osteoarthritis
Cross-sectorial Management Program for People Living with Hand Osteoarthritis: a Randomised Controlled Pilot and Feasibility Study
To investigate the research design (pilot-RCT) and feasibility of the HANDY program for people with hand osteoarthritis (version 2.0).
- Trial name
- HANDY (NCT06794632)
- Testing
- HANDY occupational therapy intervention
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Parker Research Institute
Rheumatic Arthritis
Intervention to Support Partners and Informal Caregivers of Frail RA-patients
Background Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with pain, fatigue, functional limitations, and reduced quality of life.
- Trial name
- INSPIRE (NCT07442773)
- Testing
- Caregiver support
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Stroke
YOGA-FIT: Protocol for a Crossover Trial Investigating the Feasibility and Impact of Yoga for People With Stroke
The primary objective of this mixed-methods pilot crossover study is to determine the feasibility (participant satisfaction, recruitment rate, retention, participant and assessor burden, adherence, equipment and technology…
- Trial name
- YOGA-FIT (NCT07143162)
- Testing
- LoveYourBrain Yoga
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Nova Scotia Health Authority
Emotional Disorders, Anxiety
Blended Unified Protocol for Emotional Disorders in Primary Care
The goal of this clinical trial is to learn if a "blended" therapy format (combining face-to-face therapy sessions with a smartphone app) works to treat emotional disorders, such as depression and anxiety, in adults.
- Conditions
- Emotional Disorders, Anxiety, Depression
- Trial name
- NCT07432906
- Testing
- Unified Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Aydin Adnan Menderes University
Healthy Older Adults
Health Web Te@m (1.0) an Interprofessional Web-based Group Intervention Supporting Healthy Ageing
The goal of this study is to evaluate the feasibility of Health Web - Te@m 1.0 for older adults in selected primary healthcare settings in northern Sweden.
- Trial name
- NCT07545915
- Testing
- Health Web Te@m
- Where
- Sweden
- Volunteers
- 27 people
- Sponsor
- Luleå Tekniska Universitet
Cancer
Testing the Feasibility of Balance, Activity, Quality of Life and Social Equity (BALanSE): An Activity- and Resource-oriented Rehabilitation and Palliative Care Intervention for People With Cancer
Research shows that people living with cancer often struggle to manage their energy and resources in a way that allows them to take part in the everyday activities that matter most to them.
- Trial name
- BALanSE (NCT07557043)
- Testing
- BALanSE intervention
- Volunteers
- 30 people
- Sponsor
- University of Southern Denmark
Feasibility Studies
The Aim of This Study is to Assess the Feasibility of the Study Protocol and the Acceptability of the Mobile Application-Based Intervention. The Results Will Guide the Design and Evaluation of a Definitive, Larger-scale Study to Further Examine the Efficacy of the Refined Intervention.
This study is a pilot study for a larger future research project aimed at examining the effects of patient education delivered via a mobile application on patients' self-reported receipt of information in relation to their…
- Trial name
- NCT07589803
- Testing
- Digital patient education mobile application., Standard Care (in control arm)
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Coxa, Hospital for Joint Replacement
Health-Related Quality-of-Life, Satisfaction With Care
V-CARE (Virtual Care After REsuscitation)
Out-of-hospital cardiac arrest (OHCA) survivors and their relatives may face challenges following hospital discharge, relating to mood, cognition, and returning to normal day-to-day activities.
- Conditions
- Health-Related Quality-of-Life, Satisfaction With Care, Self-management Behaviors
- Trial name
- V-CARE (NCT07498764)
- Testing
- Virtual Care After REsuscitation, Digital Information Leaflet
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Breast Cancer, Parenting Anxiety
Development and Application of a Parenting Anxiety Intervention Program for Young and Middle-Aged Female Breast Cancer Patients
This feasibility study aims to develop and test an intervention program for young and middle-aged female breast cancer patients who experience parenting concerns.
- Trial name
- NCT07331740
- Testing
- Parenting Concerns Support Program
- Volunteers
- 20 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Breast Cancer Female
Safety, Feasibility, and Outcomes of Early Rehabilitation After Breast Cancer Surgery
Breast cancer is one of the most common tumours in women. Advances in diagnosis and treatment have increased survival, but many women experience functional sequelae after breast and/or axillary surgery, including pain, reduced…
- Trial name
- EMOVE-BCS (NCT07651696)
- Testing
- Early Postoperative Rehabilitation Protocol
- Volunteers
- 110 people
- Sponsor
- Marta Aguilar-Rodriguez
Type 1 Diabetes
Adaptation of REDCHIP Intervention for the Portuguese Context
The present Feasibility Randomized Controlled Trial (FRCT) aims to assess the acceptability and effectiveness of REDCHiP intervention, targeting parents of young children with T1D, followed in two major Portuguese hospitals.
- Trial name
- REDCHIP (NCT07201779)
- Testing
- REDCHiP, Treatment As Usual Control Group
- Volunteers
- 44 people
- Sponsor
- ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Anterior Cruciate Ligament Rupture, Enhanced Recovery After Surgery (ERAS) Protocol
Effectiveness of Enhanced Recovery After Surgery (ERAS) Protocols for Arthroscopic Anterior Cruciate Ligament Reconstruction in an Ambulatory Surgery Setting
The anterior cruciate ligament (ACL) is a critical component for maintaining knee stability by resisting anterior tibial translation and internal rotation.
- Conditions
- Anterior Cruciate Ligament Rupture, Enhanced Recovery After Surgery (ERAS) Protocol, Ambulatory Surgery
- Trial name
- NCT07602231
- Testing
- Enhanced Recovery After Surgery
- Volunteers
- 115 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Stroke
Brazilian Adaptation of an Intervention Developed in Ireland to Promote Healthy Lifestyle Behaviors Post-stroke: a Feasibility Study
Introduction: Low- and middle-income countries, such as Brazil, are most impacted by the high burden of recurrent stroke. These countries also lack structured interventions to promote the adoption of healthy lifestyle behaviors…
- Trial name
- NCT07119047
- Testing
- A Brazilian adaptation of the Irish intervention "iHELP Stroke"
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Federal University of Minas Gerais