Clinical trials: Sub-fertility
Subfertility, Pregnancy
A RCT Comparing Spontaneous Natural Cycles and Human Chorionic Gonadotrophin-induced Natural Cycles in FET
This is a randomized controlled trial on the comparison of the ongoing pregnancy rate in frozen-thawed embryo transfer cycles with spontaneous ovulation and hCG-induced natural cycles.
- Trial name
- NCT02197208
- Testing
- Daily monitoring of LH and E2, hCG induced natural cycle, ultrasound
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 300 people
- Sponsor
- The University of Hong Kong
Subfertility, Female, Ovulation Disorder
Serial Progesterone Level Measurements During the Menstrual Cycle in Subfertile Women
Ovulatory dysfunction is identified in 15% of all infertile couples and it accounts for 40% of female infertility. Ovulatory dysfunction may be more subtle in women with regular menses.
- Trial name
- NCT05211583
- Testing
- Serum progesterone levels
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Turgut Aydın
Polycystic Ovarian Syndrome (PCOS), Polyendocrine Metabolic Ovarian Syndrome (PMOS)
Comparison of Clomiphene Alone Versus Clomiphene Plus Sildenafil for Ovulation in Women With Polycystic Ovary Syndrome
The goal of this randomized clinical trial is to compare the effectiveness of clomiphene citrate alone with clomiphene citrate combined with sildenafil citrate for inducing ovulation and achieving pregnancy in women with…
- Trial name
- NCT07769476
- Testing
- Clomiphene Citrate 100 mg, Sildenafil Citrate 25Mg Tab
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Nishtar Medical University
Infertility, Subfertility
Effect of hCG on Receptivity of the Human Endometrium
Worldwide, 1 in 12 couples experience difficulty in getting pregnant and seek the help of assisted reproductive technologies (ART) such as in vitro fertilization (IVF-egg is fertilized by sperm outside the body), ovarian…
- Trial name
- NCT01786252
- Testing
- human chorionic gonadotropin (hCG)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Sub Fertility, Female, Fertility Disorders
Feasibility and Safety of Fasting in Fertility Treatment
This exploratory study investigates fasting as a potential supportive therapy in infertility treatment for women suffering from infertility
- Conditions
- Sub Fertility, Female, Fertility Disorders, Cycle Disorders Menstrual, Ovulation Disorder
- Trial name
- KiWuA (NCT04942457)
- Testing
- Fasting
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Charite University, Berlin, Germany
Ovarian Failure, Thyroid Diseases
Thyroid Function and Autoimmunity in Subfertility Women and Assisted Reproductive Therapy
The assessment of ovarian reserve is well established based on the dosage of anti-Mullerian hormone (AMH). The clinical applicability of detecting thyroid autoantibodies levels has been discussed as a potential marker of…
- Trial name
- NCT06394466
- Testing
- Non Applicable
- Where
- Brazil
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Polycystic Ovarian Syndrome, Subfertility
Comparison Between the Role of Follicular Output Rate and Preovulatory Count in the Prediction of Pregnancy in Women With Polycystic Ovarian Syndrome Undergoing Intra Cytoplasmic Sperm Injection (ICSI)
Our study is observational, we are observing data from routine measurements during IVF/ICSI. Our study does not assess IVF/ICSI as an intervention, we are evaluating the role of FSI and preovulatory count which are calculated by…
- Conditions
- Polycystic Ovarian Syndrome, Subfertility, ICSI
- Trial name
- NCT02190006
- Where
- 2 sites in Egypt
- Volunteers
- 300 people
- Sponsor
- Cairo University
Intrauterine Abnormalities in Infertility
SIGnificance of Routine Hysteroscopy Prior to a First 'in Vitro Fertilization'(IVF) Treatment Cycle
BACKGROUND: Despite the numerous advances in the field of in vitro fertilisation/intracytoplasmic sperm injection (IVF/ICSI), there still exists a maximum implantation rate per embryo transferred of about 30%.
- Trial name
- inSIGHT (NCT01242852)
- Testing
- Office hysteroscopy (in combination with a 'Saline Infusion Sonography'(SIS))
- Where
- Netherlands
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Sub-fertility, Recurrent Implantation Failure
The PIP Study - Pre- IVF Immune Profiling Study
Many IVF clinics offer testing for immune cells in the blood and endometrium as it has been suggested that abnormal levels of these cells can affect fertility or the chance of an IVF cycle working.
- Trial name
- PIP (NCT03660735)
- Where
- 2 sites in United Kingdom
- Volunteers
- 250 people
- Sponsor
- University of Oxford
Subfertility
Effect of DHEA on Patients With Poor Ovarian Responds
The purpose of this study is to investigate the effect of DHEA for treatment of subfertile patients with poor ovarian reserve and post-treatment evaluation of IVF outcome.
- Trial name
- NCT02432248
- Testing
- Dehydroepiandrosterone
- Where
- China
- Volunteers
- 350 people
- Sponsor
- The Affiliated Hospital of Inner Mongolia Medical University
Male Subfertility, Oligospermia
7 NUTS Study. Diet Modification and Male Fertility.
Setting. Outpatient fertility clinic. Aim. Investigate if a modification in nutritional habits may improve in the short term the qualities of human sperm, testing two hypothesis: i) that adding to the diet a natural whole food…
- Conditions
- Male Subfertility, Oligospermia, Asthenospermia, Teratospermia
- Trial name
- NCT02063256
- Testing
- 7 nuts a day, Diet modification
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Adenomyosis of Uterus
Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms
The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis…
- Trial name
- MUSA3 (NCT07397715)
- Where
- 5 sites in Belgium, Poland and 2 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss GO Trial Group
Male Subfertility
Role of Immunoglobulin in Male Infertility
to investigate the role of IVIG in male infertility and to determine its benefits in term of semen parameters and assisted reproduction outcome
- Trial name
- NCT06423989
- Testing
- IVIG
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dr Salma kafeel Qureshi
Subfertility
BAP-EB as a Predictive Tool for Endometrial Receptivity and Pregnancy Outcome of IVF Treatment
To determine the predictive value of attachment rate of human embryonic stem cells (hESC)-derived trophoblast spheroids (BAP-EB, embryo surrogate) onto endometrial epithelial cells (EEC) on success of IVF treatment and to use the…
- Trial name
- NCT02713854
- Testing
- endometrial biopsy
- Where
- China
- Volunteers
- 240 people
- Sponsor
- The University of Hong Kong
Periodontitis, Sub-fertility
Association Study Between Periodontal Disease and Male Infertility
The aim of the present study is to examine the association between fertility parameters and the periodontal status of men attending fertility and in vitro fertilization clinic.
- Trial name
- NCT01140945
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Reproductive Issues, Subfertility
A Novel Integrative Non-invasive Embryo Selection Approach for IVF Based on MK-RS Analysis
During assisted reproductive technology treatment, embryo selection is an important process that may affect the clinical pregnancy rate.
- Conditions
- Reproductive Issues, Subfertility, IVF
- Trial name
- NCT05896709
- Testing
- MK-RS
- Where
- Hong Kong
- Volunteers
- 176 people
- Sponsor
- Chinese University of Hong Kong