Clinical trials: Subarachnoid Block
Hypotension, Ischemia
Phase III Study of Hemospan® to Prevent Hypotension in Hip Arthroplasty
The purpose of this study is to determine whether Hemospan is superior to Voluven for preventing hypotensive episodes during the perioperative period (from induction of spinal anesthesia until 6 hours after skin closure), and for…
- Trial name
- NCT00421200
- Testing
- Hemospan (MP4OX), Voluven (HES 130/0.4)
- Where
- 18 sites in Belgium, Czechia and 4 more
- Volunteers
- 375 people
- Sponsor
- Sangart
Cesarean Section Complications, Spinal Anesthesia
Vasopressor Infusion in Cesarean Delivery
Comparison will be conducted between continuous variable infusions of both drugs (Phenylephrine and Norepinephrine) with starting doses of 0.75 mcg/Kg/min and 0.1 mcg/Kg/min respectively for prophylaxis against Post-spinal…
- Trial name
- NCT03248791
- Testing
- Phenylephrine, Norepinephrine, Bupivacaine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Music Therapy, Perioperative Care
Effect of Music in Intraoperative Period
Background and Aims: Music therapy has a wide range of uses in health care practice. The aim of this study was to investigate the effects of intraoperative music played during spinal anesthesia operation on the patients'…
- Conditions
- Music Therapy, Perioperative Care, Postoperative Pain, Anxiety
- Trial name
- NCT04485650
- Testing
- music therapy, sedated group, non-sedated group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Abant Izzet Baysal University
Cesarean Birth
Prevalence of Pain During Cesarean Section
200 parturients coming for an elective cesarean delivery will receive a standard neuraxial anesthesia for the operation consisting of a spinal anesthetic and an epidural catheter (combined spinal epidural anaesthesia).
- Trial name
- NCT07851441
- Testing
- Combined spinal and epidural anesthesia
- Where
- 3 sites in Finland
- Volunteers
- 200 people
- Sponsor
- Women's Hospital HUS
Spinal Aneshtesia, Hypotension After Spinal Anesthesia
Comparing Two Different Norepinephrine Infusion Rates for Prophylaxis Against Spinal-induced Hypotension in Elderly
The current study aims to determine whether norepinephrine infusion rate (0.07 mcg/kg/min) is non-inferior to the higher dose (0.1 mcg/kg/min) in maintaining intraoperative blood pressure maintaining blood pressure of elderly…
- Conditions
- Spinal Aneshtesia, Hypotension After Spinal Anesthesia, Elderly (People Aged 65 or More)
- Trial name
- NCT07077265
- Testing
- Norepinephrine (0.1 μg/kg/min), Norepinephrine (0.07 μg/kg/min)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Kasr El Aini Hospital
Post Spinal Anesthesia Shivering
Intrathecal DEX With Bupivacaine Inpost-spinal Shivering After CS.
This prospective, randomized, double-blind, placebo-controlled study to determine whether intrathecal dexmedetomidine, administered along with hyperbaric bupivacaine for covering Cesarean delivery decreases the incidence of…
- Trial name
- DEX (NCT06942000)
- Testing
- dexmedetomidine 3mcg group, dexmedetomidine 5mcg, preservative-free 0.9% saline.
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Anesthesia, Spinal, Cesarean Section
Post Spinal Anesthesia Hypotension and Preoperative Hydration
Study of the impact of preoperative oral rehydration on the incidence of spinal anesthesia-induced hypotension for scheduled cesarean section.
- Trial name
- NCT04450667
- Testing
- Nutricia PreOp
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Spinal Anesthesia, Local Anesthetic
Age-Based and Weight-Based Bupivacaine Dosing for Pediatric Spinal Anesthesia for Elective Infra-Umbilical Surgeries
Pediatric anesthesia presents distinctive challenges, particularly concerning appropriate dosage administration of local anesthetics for spinal anesthesia (SA).
- Conditions
- Spinal Anesthesia, Local Anesthetic, Bupivacaine
- Trial name
- NCT06801600
- Testing
- Weight-based dosing, Age-based dosing
- Volunteers
- 60 people
- Sponsor
- Cairo University
Spinal Anesthesia, Intracranial Pressure Change
Effect of Spinal Needle Type on Optic Nerve Sheath Diameter
The optic nerve sheath is a continuation of the dura mater, extending along the subarachnoid space surrounding the optic nerve. Consequently, changes in intracranial pressure cause an augmentation or contraction in the diameter…
- Conditions
- Spinal Anesthesia, Intracranial Pressure Change, Optic Nerve Sheath Diameter, Orthopedic Surgery
- Trial name
- NCT06497634
- Testing
- 25 PP, 25 Q, 27 Q
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Bagcilar Training and Research Hospital
Post-Operative Confusion
High Spinal Anesthesia and the Incidence of Delirium After Cardiac Surgery
This is a feasibility study to determine if enough patients undergoing elective or urgent cardiac surgery, can be enrolled in a study where patients are randomized to receive high spinal anesthesia as an adjunct to general…
- Trial name
- NCT05374356
- Testing
- Intrathecal bupivacaine and morphine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Pain, Postoperative
Combination Effects of Pregabalin and Dexmedetomidine on Postoperative Pain
Pregabalin and dexmedetomidine have been introduced to manage postoperative pain. The present study aimed to evaluate the effect of the combination of two drugs on pain relief in patients undergoing total knee or hip arthroplasty…
- Trial name
- NCT03512574
- Testing
- Pregabalin, Dexmedetomidine, Pregabalin and dexmedetomidine
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Outcome
Norepinephrine and Phenylephrine for Spinal Anesthesia-induced Hypotension.
This study aims to explore the effects of different application modes (prophylactic and rescue strategy) of norepinephrine and norepinephrine on neonate umbilical artery pH undergoing cesarean section.
- Trial name
- NCT06508359
- Testing
- Norepinephrine, Phenylephrine
- Where
- China
- Volunteers
- 700 people
- Sponsor
- General Hospital of Ningxia Medical University
Cerebral Oxygen Saturation During Spinal Anesthesia for Cesarean Delivery
Spinal Anesthesia for Cesarean Delivery is Associated With Decreases in Regional Cerebral Oxygen Saturation as Assessed by Near- Infrared Spectroscopy
The cerebral oxygen saturation is assessed by means of near-infrared spectometry in parturients undergoing cesarean delivery under spinal anesthesia.
- Trial name
- NCT01669135
- Testing
- Spinal Anesthesia with cerebral oxygen saturation monitoring
- Where
- Greece
- Volunteers
- 34 people
- Sponsor
- University of Athens
Hip Fractures, Anesthesia, Spinal
GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip Fracture
Surgical repair of hip fractures may be performed with various anesthetic techniques, but are most commonly completed under general anesthesia (GA) or neuraxial anesthesia (NA).
- Conditions
- Hip Fractures, Anesthesia, Spinal, Anesthesia, General, Neuromuscular Blockade
- Trial name
- NCT03226080
- Testing
- Rocuronium, Sugammadex, Normal saline
- Where
- United States
- Sponsor
- Loyola University
Hip Fractures, Postoperative Pain
Evaluation of the Effectiviness of Two Different Bupivacaine Concentrations of the Pericapsular Nerve Group (PENG) Block
The use of regional anaesthesia techniques as part of multimodal analgesia in hip surgeries improves postoperative analgesia. PENG (Pericapsular nerve group) block is an effective motor sparing analgesia technique used in hip…
- Trial name
- PENG (NCT05921110)
- Testing
- Pericapsular nerve group block 0,25%, Pericapsular nerve group block 0,16%
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ilker Ital
Anaesthesia
Ultrasound - Guided Paramedian Techniques in Spinal Anesthesia
Multiple passes and attempts while administering spinal anesthesia are associated with a greater incidence of post dural-puncture headache, paraesthesia and spinal hematoma.
- Trial name
- NCT02171975
- Testing
- pre-procedure ultrasound guided paramedian spinal, Conventional landmark guided midline spinal anaesthetic
- Where
- Ireland
- Volunteers
- 100 people
- Sponsor
- Cork University Hospital
Dose-Response Relationship, Drug
The Effects of Spinal Anesthesia on ED50 and BIS50 of Etomidate for the Loss of Consciousness
The purpose of this study is to investigate the effect of spinal anesthesia on ED50 and BIS50 of etomidate for the loss of consciousness (LOC) by using up-and-down method.The hypothesis was that spinal anesthesia could…
- Trial name
- LOC (NCT03240055)
- Testing
- spinal anesthesia, etomidate
- Where
- China
- Volunteers
- 54 people
- Sponsor
- General Hospital of Ningxia Medical University
Aneurysmal Subarachnoid Hemorrhage (aSAH), Headache Disorders
Efficacy of Scalp Block in Managing Post Subarachnoid Hemorrhage Headache in Critically Ill Patients. A Single Centre Randomized Controlled Trial
Subarachnoid hemorrhage (SAH) is a devastating neurological disorder associated with significant mortality and morbidity rates, arising not just from the hemorrhage itself but also because of the catastrophic multisystem sequelae…
- Trial name
- SAH-BLOCK (NCT07307508)
- Testing
- Levobupivacaine Scalp block, Conventional analgesic therapy
- Where
- Qatar
- Volunteers
- 22 people
- Sponsor
- Hamad Medical Corporation
Anesthesia
Comparison of 3 Different Density Levobupivacaine Solutions + Fentanyl for Spinal Anaesthesia for Caesarean Delivery.
The investigator's aim is to compare the efficacy of 3 levobupivacaine solutions with different density on spinal anesthesia for caesarean delivery.
- Trial name
- NCT03956303
- Testing
- Chirocaine %0.5, Chirocaine Heavy 40, Chirocaine Heavy 60
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Spinal Anesthesia
Minimum Effective Dose of Ropivacaine for Spinal Anesthesia for Cesarean Delivery
Ropivacaine is one of commonly used anesthetics for spinal anesthesia. Usually L2-3 or L3-4 intervertebral space is chosen for spinal anesthesia.
- Trial name
- NCT02565303
- Testing
- Intervertebral space, Ropivacaine
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai 6th People's Hospital
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