Clinical trials: Subarachnoid Block
Cesarean Section
Heart Rate Variability to Predict Hypotension Following Spinal Anesthesia in Cesarean Delivery
Based on the patient's heart rate variability, the analgesia nociception index (ANI) measures the activity of the autonomic nervous system and the sympathetic/parasympathetic nervous system and expresses it as a numerical value…
- Trial name
- NCT04979039
- Testing
- analgesia nociception index (ANI) monitoring
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Bundang Hospital
Postoperative Pain, Complications
A Trial of Closed Hemorrhoidectomy Under Local Perianal Block Versus Spinal Anesthesia
Hemorrhoidectomy can be carried out under several modes of anesthesia. In western country hemorrhoidectomy usually be performed under general anesthesia, however there may be the complications resulted from general anesthesia…
- Conditions
- Postoperative Pain, Complications, Satisfaction
- Trial name
- NCT00925912
- Testing
- spinal block, Perianal block
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Hypotension, Ischemia
Phase III Study of Hemospan® for Treating Hypotension in Hip Arthroplasty
The purpose of this study is to determine whether Hemospan is superior to Voluven for treatment of hypotensive episodes during the perioperative period (from induction of spinal anesthesia until 6 hours after skin closure), and…
- Trial name
- NCT00420277
- Testing
- Hemospan (MP4OX), Voluven (HES 130/0.4)
- Where
- 22 sites in Belgium, Czechia and 3 more
- Volunteers
- 462 people
- Sponsor
- Sangart
Cystoscopy
Comparison of Hemodynamic Stability With 0.75percent and 0.5percent Hyperbaric Bupivacaine During Spinal Anesthesia in Cystoscopic Procedures
Purpose:The aim of this study is to determine the intrathecal Bupivacaine concentration(0.5% vs 0.75%) with better anesthesia and little hemodynamic disturbance during cystoscopic procedures.In comparing these bupivacaine…
- Trial name
- NCT07590544
- Testing
- 0.5% Hyperbaric Bupivicaine, 0.75% hyperbaric bupivacaine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- PAEC General Hospital, Islamabad
Postoperative Pain, Fracture Femur
Preoperative and Postoperative Comparison of Two Nerve Blocks in Intertrochanteric Fracture Surgery
Patients with intertrochanteric femur fractures experience significant perioperative and postoperative pain. Perioperative pain can complicate and prolong the anesthesia process for patients undergoing spinal anesthesia, leading…
- Trial name
- NCT07075432
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Erzincan University
Cesarean, Spinal Anesthesia
Prediction of Maternal Arterial Hypotension After Spinal Anesthesia by Passive Leg Raise Test.
Spinal anesthesia for cesarean section is associated with a high incidence of low blood pressure. However, the pathophysiology of this arterial hypotension is not unequivocal and could involve, in addition to drug vasoplegia, a…
- Trial name
- EDLIDL (NCT05133271)
- Testing
- Clinical hemodynamic and echocardiographic evaluation
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Newborns, Infant
IV Dexmedetomidine as Spinal Anesthesia Adjuvant in Infants
Spinal anesthesia in newborns is one of " Gold standard " techniques in short subumbilical surgeries (less than 30 minutes) with advantage of avoiding the risks inherent to general anesthesia.
- Conditions
- Newborns, Infant, Spinal Anesthesia
- Trial name
- RACHI_dex (NCT04598061)
- Testing
- Dexmedetomidine IV
- Where
- France
- Volunteers
- 210 people
- Sponsor
- University Hospital, Montpellier
Hypotension Drug-Induced
Effectiveness of Phenylefrine in Prevention of Hypotension During Spinal Anesthesia for Cesarean Delivery
Hypotension in patients who are taken to surgery, is a very frequent complication, when the spinal anesthetical technique is used, associating this with significant adverse effects that can lead to morbidity specially in the…
- Trial name
- NCT02979405
- Testing
- Phenylephrine
- Where
- Colombia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Universidad Industrial de Santander
Hip Fractures, Arthroplasty, Replacement, Hip
PENG Block + LIA For Endoprosthesis Surgery
The goal of this clinical trial is to learn if a new local anesthesia technique can control pain as well as the standard spinal anesthesia for adults having hip endoprosthesis surgery.
- Conditions
- Hip Fractures, Arthroplasty, Replacement, Hip, Pain, Postoperative, Anesthesia and Analgesia
- Trial name
- PENG 360° (NCT07239817)
- Testing
- Pericapsular Nerve Group Blocks with Local Infiltration Analgesia, spinal anesthesia
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ASST Gaetano Pini-CTO
Obstetrics: Elective Caesarean Delivery
Effects of Spinal Anesthesia on the Fetal Autonomic Nervous System
Elective cesarean deliveries account for over 10% of births in France and are often scheduled around 39 weeks of gestation. When feasible, spinal anesthesia is considered the gold standard in such a clinical situation.
- Trial name
- RACHISNA (NCT07333729)
- Testing
- Recording of fetal and maternal heart rate
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Lille
Post-Dural Puncture Headache, Hypotension
Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section
The goal of this clinical trial is to compare different approaches of spinal anesthesia in pregnant females who are having cesarean section.
- Conditions
- Post-Dural Puncture Headache, Hypotension, Spinal Shock, Hematoma
- Trial name
- NCT05637645
- Testing
- Midline Approach, Paramedian Approach, Taylors approach
- Where
- 4 sites in Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bahawal Victoria Hospital Bahawalpur
Continuous Fetal Heart Beat Monitor and Analysis After Spinal Anesthesia
Fetal Heart Rate Pattern After Spinal Anesthesia for Scheduled Uncomplicated Cesarean Section
Spinal anesthesia may cause sympathetic blockade which decrease peripheral vascular resistance and bradycardia and then hypotension.
- Trial name
- NCT05776186
- Testing
- Spinal anesthesia with heavy bupivacaine
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Chronic Postoperative Pain
Pain Control Following Total Hip Arthroplasty
Total hip arthroplasty (THA) is one of the most common surgical procedures performed in elderly patients, with its main indication being end-stage osteoarthritis of the hip1.
- Trial name
- NCT05062356
- Testing
- Bupivacaine Hydrochloride 0.25% Injection Solution_#2, EPINEPHrine 1:200,000 / Prilocaine HCl 4 % 1.8 ML Cartridge, Bupivacaine Hydrochloride 0.5% Injection Solution_#2
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- St. Mary's Research Center, Canada
Shivering, Spinal Anesthesia
Effect of Intrathecal Bupivacaine Temperature Variation on Prophylaxis of Shivering in Urologic Patients Undergoing Spinal Anesthesia
The aim of this study is to evaluate the effect of temperature variation of injected intrathecal bupivacaine on prophylaxis of post-spinal shivering in urological patients undergoing spinal anaesthesia.
- Trial name
- NCT07081516
- Testing
- temperature
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Kasr El Aini Hospital
Cesarean Section Complications
Impact of a Strategy Combining Morphine Savings and Anesthesia Technique on the Quality of Post-operative Rehabilitation
The aim of REHACESAR is to study the impact of an association of a low dose of neuraxial morphine and a locoregional anesthesia (TAP block or catheter for continuous wound infiltration) on quality of recovery after cesarean…
- Trial name
- REHACESAR (NCT04377984)
- Where
- France
- Volunteers
- 145 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Hypotension Drug-Induced, Spinal Aneshtesia
Effect of Lateral Decubitus Position After Spinal Anesthesia on Hemodynamic Stability in High-Risk Geriatric Patients
Spinal anesthesia is a common and preferred anesthetic technique for lower extremity orthopedic surgery in elderly patients. However, it can cause a significant drop in blood pressure (hypotension), especially in high-risk older…
- Conditions
- Hypotension Drug-Induced, Spinal Aneshtesia, Geriatric, Orthopedic Surgery Patients
- Trial name
- NCT07597148
- Testing
- Lateral Decubitus Positioning, Immediate Supine Positioning
- Volunteers
- 70 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Hypotension After Spinal Anesthesia
Carotid Ultrasound for Post-Spinal Anesthesia Hypotension in Elderly Hip Surgery
This study aims to evaluate the predictability of preoperative carotid artery-corrected flow time (CFTc) for hypotension after spinal anesthesia in patients undergoing geriatric hip replacement surgery.
- Trial name
- NCT07876063
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Vaginal Hysterectomy, Suburethral Slings
Sedation With Dexmedetomidine Versus Remifentanil in Urogynecological Surgery Under Spinal Anaesthesia
Neuraxial blocks are usually used as an anaesthetic method for urogynecological surgeries. In most patients under regional anaesthesia, premedication is given for reducing anxiety.
- Trial name
- NCT03883347
- Testing
- Dexmedetomidine, Remifentanil
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- University of Athens
Cesarean Section, Restless Leg Syndrome
Neuraxial Anesthesia and Restless Leg Syndromes in Cesarean
The restless leg syndromes is a common sensorimotor disorder of unknown cause affecting approximately 10% of the population. Different literature had different views on the association between neuraxial anesthesia and the…
- Trial name
- NARELESS (NCT00872248)
- Testing
- Spinal anesthesia, Epidural anesthesia
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Nanjing Medical University
Comparing 2 Techniques of iv Oxytocin Causing Hemodynamic Changes
Compare Hemodynamic Effect of Oxytocin Bolus and Infusion During Cesarean Section Under Spinal Anesthesia
Oxytocin is routinely used during a cesarean section to promote uterine contraction and prevent postpartum hemorrhage. It is typically administered immediately after delivery of the baby, either as a slow intravenous bolus…
- Trial name
- NCT07687355
- Testing
- Oxytocin bolus
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Hayatabad Medical Complex
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