Clinical trials: Subarachnoid Block
Hepatectomy, Pain, Postoperative
Spinal Anesthesia For Enhanced Recovery After Liver Surgery
This project proposes to compare epidural versus spinal anesthesia in patients having liver resection surgery. The investigators hypothesize that spinal anesthesia will result in improved blood pressure control postoperatively…
- Conditions
- Hepatectomy, Pain, Postoperative, Liver Neoplasms
- Trial name
- SAFER-L (NCT03715517)
- Testing
- Continuous thoracic epidural analgesia, Spinal anesthesia with intrathecal morphine, Bupivacaine 0.75% in Dextrose Inj 8.25%
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- University of Manitoba
Spinal Anesthesia, Cesarean Section
Predicting Spinal Hypotension in Cesarean Section
This prospective observational study investigates the predictive value of anthropometric and hemodynamic indices for spinal anesthesia-induced hypotension (SAIH) during cesarean section.
- Conditions
- Spinal Anesthesia, Cesarean Section, Hypotension
- Trial name
- prediction (NCT07499947)
- Where
- Turkey (Türkiye)
- Volunteers
- 321 people
- Sponsor
- TC Erciyes University
Sedation, Spinal Anesthesia
Sedation Using Virtual Reality During Surgery Under Spinal Anesthesia
During spinal anesthesia, sedation is performed using intravenous sedative for the patient's comfort and appropriate surgical environment.
- Trial name
- NCT03055663
- Testing
- Sedation by watching virtual reality sedative program, Sedation by using intravenous sedative, Midazolam
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Seoul National University Hospital
Hemorrhoids, Postoperative Pain
Pudendal Nerve Block for Hemorrhoidectomy
Patients undergoing Milligan-Morgan hemorrhoidectomy will be randomized to receive or not the pudendal nerve block after the spinal anesthesia.
- Trial name
- NCT04251884
- Testing
- Local anesthetic (ropivacaine)
- Where
- Switzerland
- Volunteers
- 49 people
- Sponsor
- Francesco Mongelli
Anesthesia, General, Anesthesia, Spinal
The Effect of General and Spinal Anesthesia on Neutrophil-to-lymphocyte Ratio
The aim of the study was to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV)…
- Conditions
- Anesthesia, General, Anesthesia, Spinal, Umbilical Cord
- Trial name
- NCT05409885
- Testing
- General anesthesia, Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Hypotension, Spinal Anesthesia
Midodrine for Prophylaxis Against Post Spinal Hypotension in Elderly Population
Hip fracture is a common and serious healthcare problem which commonly affects elderly populations. The common route of anesthesia for hip arthroplasty is spinal anesthesia.
- Conditions
- Hypotension, Spinal Anesthesia, Elderly
- Trial name
- NCT05548985
- Testing
- Midodrine Oral Tablet, Metoclopramide
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Postoperative Pain
Adding Different Additives to Bupivacaine-fentanyl Mixture in Spinal Anesthesia for Cesarean Section
Spinal anesthesia is widely used in cesarean section, but it is associated with high incidence of side effects. To reduce the occurrence of side effects, intrathecal adjuvant was recommended to use in spinal anesthesia, with the…
- Trial name
- NCT04464616
- Testing
- spinal anaesthesia
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Cervical Incompetence in Pregnancy as Antepartum Condition
Hyperbaric Prilocaine Compared With Hyperbaric Bupivacaine in Cervical Cerclage?
Patients that have a "cervical stitch" (cervical cerclage) require an anaesthetic. The most common choice is a spinal block. This is an injection in the back that makes the lower half of the body become temporarily numb and weak.
- Trial name
- PRILOCC (NCT04394533)
- Testing
- Prilocaine (Hyperbaric 2%), Bupivacaine (Hyperbaric 0.5%)
- Where
- United Kingdom
- Volunteers
- 129 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Shivering
Comparison of Prophylactic Use of Tramadol Versus Ketamine for Prevention of Post Spinal Anesthesia Shivering
The goal of this clinical trial is to compare the effectiveness of tramadol versus ketamine in preventing shivering after spinal anesthesia in adult patients (ages 20-65) undergoing elective lower abdominal or inguinoscrotal…
- Trial name
- KETRA4PSAS (NCT07043049)
- Testing
- Tramadol, Ketamine
- Where
- 2 sites in Pakistan
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Syed Muhammad Abbas
Caesarean Section, Spinal Anesthesia
Evaluating the Effectiveness of Ondansetron Versus Dexamethasone Versus Placebo for the Control of Intraoperative Nausea and Vomiting in Patients Undergoing Lower-segment Caesarean Section Under Spinal Anesthesia
The goal of this randomized controlled trial is to evaluate the effectiveness of Ondansetron, Dexamethasone, and Placebo for intraoperative nausea and vomiting in patients undergoing caesarian section under spinal anesthesia.
- Trial name
- ODP (NCT05583214)
- Testing
- Ondansetron 8mg, Dexamethasone 8mg, Normal saline
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Muhammad Mubariz
Analgesia, Acute Pain
Comparison of the Effects of QLB 2 and QLB 3 on Post-operative Analgesia in Cesarean Section Surgery
This study evaluates the post-operative analgesic effects of quadratus lomborum block 2 and 3 (QLB 2, 3) in patients having cesarean section with spinal anesthesia.
- Conditions
- Analgesia, Acute Pain, Chronic Pain
- Trial name
- NCT04364906
- Testing
- Regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ondokuz Mayıs University
Hypotension, Obstetrical Complication of Anesthesia
Comparison of Norepinephrine and Ephedrine on Hypotension After Spinal Anesthesia in Parturients
Incidence of hypotension is high in parturients after spinal anesthesia. Ephedrine could be used to treat hypotension but lead to lower fetal pH as well.
- Conditions
- Hypotension, Obstetrical Complication of Anesthesia, Complications; Cesarean Section
- Trial name
- NCT02542748
- Testing
- Norepinephrine, Ephedrine
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Air Force Military Medical University, China
Cesarean Sections
Thoracic vs Lumbar Spinal Anesthesia for Cesarean Delivery
This randomized controlled trial aims to compare the effects of thoracic segmental spinal anesthesia and conventional lumbar spinal anesthesia on postoperative recovery in patients undergoing elective cesarean section.
- Trial name
- NCT07567612
- Testing
- Thoracic Segmental Spinal Anesthesia, Lumbar Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Adiyaman University Research Hospital
Post Spinal Anaesthesia Hypotension
Comparison Between Intravenous Hydrocortisone and Ondansetron in Prevention of Post Spinal Anesthesia Hypotension
The purpose of this study is to assess and contrast the effectiveness of intravenous ondansetron and intravenous hydrocortisone in avoiding spinal anesthesia-induced hypotension.
- Trial name
- NCT06930456
- Testing
- hydrocortisone, ondansetron
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Nada kamel Elgamal
Spinal Anesthesia, Pregnancy
Preoperative Shock Indexes and Post-Spinal Hypotension in Cesarean Surgery
This prospective observational study aims to evaluate the predictive performance of preoperative Shock Index (SI) and Modified Shock Index (MSI) for hypotension following spinal anesthesia in elective cesarean surgery.
- Conditions
- Spinal Anesthesia, Pregnancy, Hypotension Postprocedural
- Trial name
- NCT07500519
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Marmara University
Head-Down Tilt Following Spinal Anesthesia
Cephalic Spread of Block With Head Down Tilt in Spinal Anaesthesia - A Randomised Controlled Study
Subarachnoid block has become an established and reliable method of providing anaesthesia for lower abdominal and lower limb surgeries. Several factors determine the spread of local anaesthetic solutions in CSF.
- Trial name
- NCT03491319
- Testing
- Group X - head low tilt, Group Y - head low tilt, Group C - neutral
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nitte University
Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension
Ephedrine vs. Nor Epinephrine Infusion in Preventing Hypotension After Spinal Anesthesia for Cesarean Section
The purpose of the study is to determine if norepinephrine is more effective as a continuous intravenous (IV) infusion compared to continuous IV ephedrine associated with crystalloid loading for maintaining blood pressure during…
- Conditions
- Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension, Complications; Cesarean Section
- Trial name
- NCT02477501
- Testing
- Norepinephrine, Ephedrine
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Total Knee Replacement, Optic Nerve Sheath Diameter Measurement
The Effect of Epidural Anesthesia on Optic Nerve Sheath Diameter Measurements in Total Knee Prosthesis Surgery
This study investigates the effects of epidural anesthesia on intracranial pressure (ICP) by using ultrasonographic optic nerve sheath diameter (ONSD) measurements as a non-invasive indicator.
- Conditions
- Total Knee Replacement, Optic Nerve Sheath Diameter Measurement, Intracranial Pressure Change
- Trial name
- NCT07458321
- Testing
- Bupivacaine %0.25 (isobaric), Bupivacaine %0.5 (hyperbaric)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Anesthesia, Spinal, Elderly
Influence Of Low Dose Intrathecal Naloxone On Bupivacaine - Fentanyl Spinal Anaesthesia For Lower Limb Orthopedic Surgery In Elderly Patients
Fentanyl is a safer alternative than morphine in the management of postoperative pain in elderly. However, pruritus, nausea and vomiting are unwanted side effects of intrathecal fentanyl administration, that can decrease patient…
- Trial name
- NCT04673812
- Testing
- Bupivacaine-fentanyl
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Kasr El Aini Hospital
Hip Fractures, Elderly Patients
Comparison of Phenylephrine and Ephedrine in the Treatment of Hemodynamic Disorders After Spinal Anesthesia in the Elderly
Spinal anesthesia is often used for lower limb surgery in elderly. Hypotension is a side effect of spinal block. In this study, intravenous ephedrine and phenylephrine will be compared with each other to prevent spinal…
- Conditions
- Hip Fractures, Elderly Patients, Spinal Anesthesia, Lower Limb Surgery
- Trial name
- HypoGer (NCT03858465)
- Testing
- Ephedrine, Phenylephrine
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Warsaw
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