Clinical trials: Subarachnoid Block
Hypotension, Hip Fractures
Acute Hip Fracture and Spinal Anaesthesia Injection Time
The systemic effects of spinal anesthesia is not fully known. Our aim of this study is to assess whether there is a difference in hemodynamic effects if the spinal dose is given fast (15s) or slow (90s) in elderly patients with…
- Conditions
- Hypotension, Hip Fractures, Anesthesia
- Trial name
- NCT05564741
- Testing
- Norepinephrine 1 MG/ML
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Sahlgrenska University Hospital
Shivering Caused by Spinal Anesthesia
COMPARISON OF INTRAVENOUS DEXMEDETOMEDINE AND TRAMADOL FOR POST OPERATIVE SHIVERING AFTER SPINAL ANESTHESIA FOR CAESAREAN SECTION
To compare the mean time of cessation of post-operative shivering after receiving intravenous dexmedetomidine versus tramadol in patients undergoing caesarean delivery under spinal anaesthesia.
- Trial name
- NCT07332572
- Testing
- Tramadol, Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
Fluid Overload, Anesthesia; Adverse Effect, Spinal and Epidural
Can Vena Cava Ultrasound Guided Volume Repletion Prevent Spinal Induced Significant Hypotension in Elective Patients?
Aim of this study is to determine whether Inferior Vena Cava analyzed by trans-thoracic echocardiography is an effective method to guide titrated fluid repletion in non critical patients, in order both to decrease post procedural…
- Conditions
- Fluid Overload, Anesthesia; Adverse Effect, Spinal and Epidural, Regional Anesthesia Morbidity
- Trial name
- NCT02271477
- Testing
- Ultrasound-guided volemic repletion
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Hypotension, Ischemia
Phase III Study of Hemospan® for Treating Hypotension in Hip Arthroplasty
The purpose of this study is to determine whether Hemospan is superior to Voluven for treatment of hypotensive episodes during the perioperative period (from induction of spinal anesthesia until 6 hours after skin closure), and…
- Trial name
- NCT00420277
- Testing
- Hemospan (MP4OX), Voluven (HES 130/0.4)
- Where
- 22 sites in Belgium, Czechia and 3 more
- Volunteers
- 462 people
- Sponsor
- Sangart
External Cephalic Version
Success of External Cephalic Version Study
The purpose of this study is to determine the best way to optimize the success of external cephalic version (turning the baby from the outside).
- Trial name
- NCT03106753
- Testing
- Bupivacaine, Terbutaline
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ankle Surgery
Quality of Recovery at Days 5-7 After Ankle Surgery: a Multicenter Study in Seine-Maritime
Ankle fractures are among the most common fractures in trauma care, with an estimated annual incidence of 100 to 150 per 100,000 inhabitants and a marked increase after age 40.
- Trial name
- QoR - CHEVILLE (NCT07814937)
- Testing
- Assessment of recovery quality on days 5-7 after ankle surgery
- Where
- 4 sites in France
- Volunteers
- 260 people
- Sponsor
- University Hospital, Rouen
PONV
Chewing Gum to Prevent Nausea and Vomiting After Caesarean Section Under Spinal Anaesthesia
Our study aims to determine if there is a difference in a self-reported incidence of nausea and vomiting in women who are given chewing gum following elective caesarean section under spinal anaesthesia compared to those who do…
- Trial name
- NCT04191694
- Testing
- Chewing Gum, Ondansetron 4 MG
- Where
- Ireland
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Coombe Women and Infants University Hospital
Analgesia, Pain Management
Clinical Impact of IPACK Block Addition to Suprainguinal Fascia Iliaca Block
In our clinic, routine suprainguinal fascia iliaca block (SIFIB) has been administered for postoperative analgesia in patients undergoing knee arthroplasty.
- Conditions
- Analgesia, Pain Management, Acute Pain
- Trial name
- NCT06054945
- Testing
- SIFIB (suprainguinal fascia iliaca block), IPACK (Interspace between the popliteal artery and capsule of the posterior knee ), Patient controlled anagesia device
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Samsun University
Analgesia, Postoperative Pain, Acute
Effects of Pericapsular Nerve Group Block on Postoperative Recovery for Total Hip Arthroplasty
The hypothesis of this study is that patients who undergo PENG block in before Total Hip Artroplasthy (THA) surgery with spinal anesthesia will have reduced postoperative pain scores, less need for opioid analgesics and earlier…
- Trial name
- NCT06183528
- Testing
- Pericapsular Nerve Group (PENG) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Umraniye Education and Research Hospital
Spinal Induced Hypotension, Elderly
Norepinephrine Versus Phenylephrine for Preventing Spinal Anesthesia Induced Hypotension in Elderly
Various regimens were used for prevention of hypotension; most of these regimens included the use of vasopressors. Ephedrine is commonly used vasopressor for management and prophylaxis of hypotension; however, ephedrine is…
- Trial name
- NCT04195321
- Testing
- Norepinephrine, phenylephrine
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Kasr El Aini Hospital
Antishivering Effects
Diluting With Cerebrospinal Fluid Versus Traditional Intrathecal Administration: Antishivering Effects
This prospective randomized double-blinded study was conducted to compare the antishivering effects of two different types of intrathecal administration.
- Trial name
- NCT02189655
- Testing
- bupivacaine 0.5% 2.5 mL diluting with cerebrospinal fluid
- Where
- China
- Sponsor
- China Medical University, China
Cesarean Section Complications, Spinal Anesthetic Toxicity
Comparison of Vasopressor Boluses for Management of Hypotension After Spinal Anesthesia
In this study the investigators will compare the efficacy and side effects of two doses of norepinephrine bolus (6 mcg and 10 mcg) in management of maternal hypotensive episode after subarachnoid block during Cesarean delivery.
- Trial name
- NCT03712111
- Testing
- Norepinephrine 6 mcg, Norepinephrine 10 mcg, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Cairo University
Hip Fractures, Supra-inguinal Fascia Iliaca Block
Preoperative Supra-inguinal Fascia Iliaca Block for Positioning Analgesia in Hip Fracture Patients Undergoing Spinal Anesthesia
The goal of the clinical trial is to learn if preoperative Superficial Inguinal Fascia Iliaca (SIFI) block works to reduce pain during positioning for spinal anesthesia.
- Conditions
- Hip Fractures, Supra-inguinal Fascia Iliaca Block, Spinal Anesthesia
- Trial name
- NCT07556614
- Testing
- Isobaric bupivacaine 0.5%
- Where
- Pakistan
- Volunteers
- 132 people
- Sponsor
- Ghurki Trust and Teaching Hospital
Opioid Consumption, Postoperative, Pain, Postoperative
Comparison of Pain Relief Methods for Hip Surgery: A Study on Two Different Nerve Block Techniques
This prospective randomized comparative study aims to compare the analgesic efficacy of pericapsular nerve group block (PENG) and lumbar erector spinae plane block (L-ESP) groups to relieve postoperative pain in participants over…
- Conditions
- Opioid Consumption, Postoperative, Pain, Postoperative, Nerve Block, PENG Block
- Trial name
- NCT06821516
- Testing
- Evaluation of the postoperative analgesic effectiveness of PENG block in participants undergoing total hip arthroplasty under spinal anesthesia, Evaluation of the postoperative analgesic effectiveness of lumbar erector spinae block in participants undergoing total hip arthroplasty under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Efficiency, Spinal Anesthesia
The Efficiency of Preoperative Pericapsular Nerve Group Block Applied With Ultrasound and Success of Spinal Anesthesia
We aimed to investigate the effectiveness of the pericapsular nerve group (PENG) block applied with preoperative ultrasonography (USG) in patients who were operated on under spinal anesthesia due to hip fracture and whether it…
- Conditions
- Efficiency, Spinal Anesthesia, Block
- Trial name
- PENG (NCT06209372)
- Testing
- Group PENG, Group C
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Suleyman Demirel University
Spinal Anaesthesia, Obesity
An Ultrasound Guided Automated Spinal Landmark Identification System
Neuraxial ultrasonography has been shown a safe and effective technique to enhance the overall success rate of lumbar puncture and reduce the number of injection attempts.
- Trial name
- uSINE (NCT03687411)
- Testing
- Neuraxial ultrasonography
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- KK Women's and Children's Hospital
Regional Anesthesia Morbidity
Feasibility of Real-time Ultrasound-guided Spinal Anesthesia Using Dynamic Needle Tip Positioning
Confirming the L4-L5 or L3-L4 vertebrae level with ultrasound in real time for adults who scheduled elective surgery under spinal anesthesia, and introduce the spinal needle into the subarachnoid space.
- Trial name
- NCT04001387
- Testing
- Real-time ultrasound guided spinal anesthesia
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Pregnancy Induced Hypertension
Fractionated Vs Single Dose Injection for Spinal C-Section in Patients With Pregnancy-Induced Hypertension
The aim of this study was to compare haemodynamic changes, total dose of ephedrin requirement, and level of sensory blockade between fractionated dose and single dose spinal anesthesia injection in obstetric patients with…
- Trial name
- NCT03693638
- Testing
- Bupivacaine-fentanyl
- Where
- Indonesia
- Volunteers
- 42 people
- Sponsor
- Universitas Indonesia
Spinal, Hypotension
Prediction of Hypotension Using Perfusion Index Following Spinal Anesthesia in Lower Segment Caesarean Section
Spinal anesthesia for caesarean section is invariably associated with variable degree of hypotension. Hypotension that occurs may be detrimental to various organ system due to inadequate perfusion.
- Conditions
- Spinal, Hypotension, Perfusion Index
- Trial name
- NCT03319433
- Testing
- Perfusion Index
- Volunteers
- 130 people
- Sponsor
- Paropakar Maternity and Women's Hospital
Spinal Anesthesia
The Effect of Spinal Flexion in the Lateral Decubitus Position on the Unilaterality During Spinal Anesthesia
For unilateral spinal block, spinal local anesthetics should take effect on the spinal nerves of one side. With full flexion of the spine, the cauda equina becomes tightened and hangs in the middle of the subarachnoid space.
- Trial name
- NCT01321684
- Testing
- lateral decubitus position with full spinal flexion, lateral decubitus position without spinal flexion
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Seoul National University Hospital
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