Clinical trials: Subarachnoid Block
Pregnancy Related
Pulmonary Echography and BNP Value Pre- and Post- Elective Cesarean Section in Spinal Anesthesia
Pregnancy is characterized by many biohumoral changes: circulation, respiratory mechanics, oncotic pressure, vascular permeability and many other systems are affected.
- Trial name
- NCT03851679
- Testing
- B-Type natriuretic peptide (BNP) serum values, Pulmonary echography, urine collection
- Volunteers
- 80 people
- Sponsor
- University of Udine
Paraspinal Muscle Mass and Spinal Anaesthesia
Non-Pharmacological Factors on Spinal Block Duration
The aim of this study is to evaluate the effects of non-pharmacological factors-such as age, sex, body mass index, paraspinal muscle mass, vertebral canal anatomy, patient positioning, and injection technique-on the duration of…
- Trial name
- NCT07638280
- Testing
- spinal anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Anesthesia, Obstetrical, Anesthesia, Spinal
Phenylephrine and Hypotension During Spinal Anesthesia for Cesarean Section
Pregnant women with a positive preoperative Supine stress test were found to be a subgroup at increased risk of symptomatic hypotension after spinal anesthesia
- Trial name
- NCT02958215
- Testing
- Phenylephrine
- Where
- Egypt
- Volunteers
- 980 people
- Sponsor
- Assiut University
Pain, Postoperative
The Effect of Bilateral Erector Spina Plane Block on Postoperative Analgesia in Cesarean Section Under SpinalAnaesthesia
Acute pain after cesarean section (SC) can be variable. Untreated pain can affect patients' life quality. Currently regional nerve blocks are frequently used as a part of multimodal analgesia.
- Trial name
- NCT05695625
- Testing
- Spinal anesthesia + bilateral erector spine plane block, Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Ankara University
Hypotension, Pregnancy
ET50 With Fentanyl for Post Caesarean Section Spinal Hypotension
Hypotension is extremely common after induction of spinal anesthesia for cesarean delivery. Anesthetic blockade of the sympathetic outflow of the spinal cord causes vasodilation, and is one cause of this hypotension.
- Trial name
- ET-50-Fent (NCT01896960)
- Testing
- Bupivacaine with 15 micrograms of fentanyl
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Hip Fractures, Postoperative Pain
Evaluation of the Effectiviness of Two Different Bupivacaine Concentrations of the Pericapsular Nerve Group (PENG) Block
The use of regional anaesthesia techniques as part of multimodal analgesia in hip surgeries improves postoperative analgesia. PENG (Pericapsular nerve group) block is an effective motor sparing analgesia technique used in hip…
- Trial name
- PENG (NCT05921110)
- Testing
- Pericapsular nerve group block 0,25%, Pericapsular nerve group block 0,16%
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ilker Ital
Pain, Postoperative
The Effect of IV Dexamethasone on the Duration of Analgesia of Spinal Anaesthesia for C-Sections at a Jamaican Hospital
Dexamethasone is one of many adjuncts tested to prolong the duration of spinal anesthesia and its analgesic effect. The intent of this, a single-site, double-blinded, randomized controlled trial, is to determine if a single…
- Trial name
- NCT04624360
- Testing
- Dexamethasone
- Where
- Jamaica
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Anorectal Surgery Haemodynamic Changes
Haemodynamic Effects During Anorectal Surgery: a Comparison of the Jack -Knife and Lithotomy Position
Background and Goal of Study: Minimal dose of spinal hyperbaric bupivacaine is commonly performed for adult anorectal surgery. This kind of anaesthesia can cause sinus bradycardia and hypotension wich reason is body position…
- Trial name
- NCT02115178
- Testing
- Lithotomy or Prone position
- Where
- Lithuania
- Volunteers
- 155 people
- Sponsor
- Lithuanian University of Health Sciences
Cesarean Section, Transversus Abdominis Plane (TAP) Block
The Effect of TAP Block on Maternal-Infant Bonding
Cesarean delivery is a common surgical procedure that is typically performed under spinal anesthesia. Postoperative pain management has a significant impact on both the mother's physical recovery and the quality of…
- Trial name
- NCT06858891
- Testing
- Transversus abdominis plane (TAP) block
- Volunteers
- 132 people
- Sponsor
- Adiyaman University Research Hospital
Spinal Anesthesia, Cesarean Section
The Role of Carotid Flow Time-Based Fluid Administration in Caesarean Section
It has been reported that corrected carotid flow time (FTc) may indicate the responsiveness of spontaneously breathing patients to fluid therapy.
- Trial name
- NCT06048497
- Testing
- Corrected carotid flow time measurement guided fluid preload
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Cukurova University
Spinal Anesthesia Induced Hypotension, Caeserian Section
AI Prediction of Post-Induction Hypotension in Cesarean Sections With Spinal Anesthesia
The cesarean section, medically necessary for both the mother and the baby in certain cases, is a life-saving operation.The most commonly used anesthesia method worldwide is spinal anesthesia.
- Trial name
- NCT06158542
- Testing
- Spinal Anesthesia, Blood Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 370 people
- Sponsor
- Hacettepe University
Adverse Anesthesia Outcome
Analgesia in Inguinal Hernia Repair Using a Cyclooxygenase-2-specific Inhibitor
Acute pain is the result of activating nociceptive pathways in both the peripheral and central nervous system. The origin of most acute pain from surgical stimulation is the mechanical trauma of the local tissue and the…
- Trial name
- NCT02884986
- Testing
- Etoricoxib
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Bnai Zion Medical Center
Post-Dural Puncture Headache
Is Aminophylline More Effective Than Neostigmine/Atropine Mixture in the Treatment of Post-dural Puncture Headache
Objectives: To compare the safety and efficacy of IV aminophylline versus IV neostigmine/atropine mixture in the treatment of post-dural puncture headache (PDPH).
- Trial name
- RCT (NCT03997006)
- Testing
- IV Aminophylline, IV Neostigmine Methylsulfate + Atropine Sulphate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Cesarean Section; Complications, Wound, Infection (Following Delivery), Postoperative Pain
Comparison of Two Routes of Administration of a Multimodal Analgesic Protocol in Postoperative Cesarean Section
Many drugs with various mechanisms of action are used for postcaesarean pain relief. Although the response to pain relief is sometimes believed to be individual, it is very important to establish the most effective with the least…
- Conditions
- Cesarean Section; Complications, Wound, Infection (Following Delivery), Postoperative Pain, Spinal Anaesthesia During the Puerperium
- Trial name
- NCT03626753
- Testing
- Nefopam 20 MG/ML, "Nefopam (Acupan)" 20 MG/ML Injectable Solution, "Acetaminophen, (paracetamol)" 500Mg Tab
- Where
- Tunisia
- Volunteers
- 200 people
- Sponsor
- Centre de Maternité de Monastir
Hypotension and Shock, Excessive Amount of Blood / Fluid Infusion
Predict Fluid Responsiveness in Spinal Anesthesia
Spinal anesthesia is still the regional anesthesia technique most widely employed in everyday clinical practice. The most feared and common of its well known side effects consist in an abrupt reduction of systemic vascular…
- Trial name
- CERU-1401 (NCT02070276)
- Testing
- Trans-thoracic echocardiography, Passive Leg Raising Test
- Where
- Switzerland
- Volunteers
- 429 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Obesity, Hip Arthroplasty
Impact of Spontaneous Breathing on Ventilation Distribution in Obese Patients
General anesthesia (GA) and paralysis are factors which facilitate atelectasis formation, especially in obese patients. Spontaneous breathing can reduce the amount of atelectasis.
- Conditions
- Obesity, Hip Arthroplasty, General Anesthesia, Spinal Anesthesia
- Trial name
- NCT01382927
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Technische Universität Dresden
Elderly Patients
Correlation of the Dural Sac Dimension With the Spread of Spinal Anesthesia
Cerebrospinal fluid volume is an important factor that influences peak block height and regression of sensory and motor blockade.
- Trial name
- NCT04065763
- Testing
- Ultrasound assessment of dural sac dimension
- Where
- South Korea
- Volunteers
- 41 people
- Sponsor
- SMG-SNU Boramae Medical Center
Surgery Related to Lower Extremity Under Spinal Anesthesia
Population Pharmacodynamic Modeling of the Sedative and Side Effects of Propofol
Sedation during spinal anesthesia is very useful for patients' comfort. However, intermittent bolus of sedative frequently results in inappropriate sedation which comes with various side effects such as patients' discomfort and…
- Trial name
- NCT02173340
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Pain
Effect of Gabapentin Enacarbil on Opioid Consumption and Pain Scores
Opioids are effective analgesics, but cause side effects including sedation, respiratory depression, low blood pressure, nausea, and constipation.
- Trial name
- NCT02840240
- Testing
- Gabapentin enacarbil
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- The Cleveland Clinic
Cesarean Section Complications
Perfusion Index and Pleth Variability Index in Cesarean Section.
The aim of this study is to investigate the predictability of hypotension by using PI and PVI in pre-and post-spinal anesthesia periods in cesarean section cases in the sitting position.
- Trial name
- NCT04195087
- Testing
- Masimo Radical-7® Pulse CO-Oximeter®
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Antalya Training and Research Hospital
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