Clinical trials: Subarachnoid Block
Anesthesia
The Efficacy of Pregabalin on the Duration of the Spinal Anesthesia and the Early Postoperative Pain After Total Knee Arthroplasty
the purpose of this study is to evaluate the effectiveness of administration of pregabalin 2 hours preoperatively on the onset and the duration of the spinal anesthesia in total knee arthroplasty and the role of pregabalin in…
- Trial name
- NCT05071118
- Testing
- Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Lower Limb Orthopedic Surgery
Intravenous Dexmedetomidine Versus Midazolam in Preventing Shivering in Trauma Patients Undergoing Lower Limb Orthopedic Surgery Under Spinal Anesthesia
Shivering is a common and significant complication following spinal anesthesia, with a reported incidence of 40-60% especially in trauma patients due to pain, stress response, blood loss, and disrupted thermoregulation.
- Trial name
- NCT07300826
- Testing
- Dexmedetomidine, Midazolam
- Volunteers
- 100 people
- Sponsor
- Assiut University
Incidence of Spinal Anesthesia Preference
Visual Education for Spinal Anesthesia Acceptance
Primary outcome: To determine the incidence of spinal anesthesia preference after exposure to the visual information catalog. Secondary outcomes: To analyze independent (age, education, profession, previous experiences) and…
- Trial name
- NCT06910826
- Where
- Turkey (Türkiye)
- Volunteers
- 318 people
- Sponsor
- Istinye University
Sedative Adverse Reaction
The Effect of Real-time Binaural Sound on Sedation Using Dexmedetomidine
The aim of the study is to evaluate whether real-time binaural sound affects the dose of dexmedetomidine in patients undergoing sedation with dexmedetomidine after spinal anesthesia.
- Trial name
- NCT04866433
- Testing
- Real-time binaural sound, Music, Control
- Where
- South Korea
- Volunteers
- 189 people
- Sponsor
- Seoul National University Hospital
Surgery, Anxiety
Investigation of the Effects of Music on Anxiety During Operations Under Spinal Anaesthesia at an Hospital in Cambodia
This study investigates he effects of intra-operative music on anxiety levels during procedures under spinal anaesthesia at a surgical centre in Cambodia.
- Trial name
- NCT04169971
- Testing
- Music
- Where
- Cambodia
- Volunteers
- 24 people
- Sponsor
- Children's Surgical Center, Cambodia
Healthy Female Volunteer
Fentanyl Versus Midazolam as an Adjunct to Spinal Anesthesia
It is well documented in the practice of anesthesia the effectiveness of bupivacaine when added with other adjuvants including midazolam, opioids, and ketamine during neuraxial spinal block for cesarean delivery, however…
- Trial name
- Spinal Block (NCT06917898)
- Testing
- Spinal Anesthesia with Bupivacaine and Fentanyl, Spinal Anesthesia with Bupivacaine and Midazolam
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Makassed General Hospital
Pancreatic Cancer
Effectiveness of the Transversus Abdominis Plane Block Associated With Opioid Spinal Anesthesia on Analgesia After Cephalic Duodenopancreatectomy
Duodenopancreatectomy is a major, risky surgery that causes significant post-operative pain. Optimizing perioperative analgesia remains a challenge, and requires multimodal management, notably involving locoregional analgesic…
- Trial name
- DPC-RATAP (NCT06499792)
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Strasbourg, France
Perioperative Infusion, Ephedrine
Prophylactic Perioperative Infusion of Ephedrine Versus Noradrenaline in Patients Undergoing Cesarean Delivery Under Spinal Anesthesia
This study aimed to compare the effects of prophylactic ephedrine and nor-epinephrine infusion on maternal hemodynamics and neonatal outcomes following spinal anesthesia in cesarean deliveries.
- Conditions
- Perioperative Infusion, Ephedrine, Noradrenaline, Cesarean Delivery
- Trial name
- NCT07067944
- Testing
- Ephedrine, Noradrenaline
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Pruritus Caused by Drug
Ondansetron Use for Preventing Pruritus in Patients Undergoing Cesarean Section
Opioids are often added with a local anesthetic to enhance the duration and quality of spinal anesthesia for cesarean delivery patients.
- Trial name
- NCT06297499
- Testing
- Ondansetron 8mg
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Postoperative Pain, Cesarean Section Pain
Comparison of Dexmedetomidine + Ketamine for Postoperative Pain in C-Section
This study aims to compare three different doses of dexmedetomidine, when combined with a fixed dose of ketamine, for pain control in women undergoing cesarean section.
- Trial name
- KETODEX-CS (NCT07022821)
- Testing
- Dexmedetomidine, ketamine
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Fatima Memorial Hospital
Inguinal Hernia Unilateral
Comparison of Quadro-Iliac Plane Block and Transversalis Fascia Plane Block for Open Inguinal Hernia Repair
This prospective observational cohort study aims to compare the postoperative analgesic effectiveness of the quadro-iliac plane block (QIPB) and transversalis fascia plane block (TFPB) in patients undergoing elective unilateral…
- Trial name
- NCT07864064
- Testing
- Quadro iliac Plane Block, Transversalis Fascia Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Vezirköprü State Hospital
Femoral Neck Fractures, Blood Loss, Surgical
Effect of Regional Anesthesia Techniques on Perioperative Blood Loss in Femoral Neck Fracture Surgery
This retrospective observational study evaluates the effect of different regional anesthesia techniques on perioperative blood loss in patients undergoing femoral neck fracture surgery.
- Conditions
- Femoral Neck Fractures, Blood Loss, Surgical, Postoperative Pain
- Trial name
- NCT07702084
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Pregnancy, Cesarean Delivery
Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia
Transthoracic echocardiography (TTE) has been introduced in anesthesia and intensive care practice to assess the volume status and predict fluid responsiveness, with a few studies performed on pregnant women (5).
- Conditions
- Pregnancy, Cesarean Delivery, Spinal Anesthesia Induced Hypotension, Cardiac Output Measurement
- Trial name
- NCT06654687
- Testing
- Transthoracic Echocardiography, Ringer lactate 1000 ml, Albumin
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Sameh Fathy
Ceserean Section, Obstetric Quality of Recovery
Anesthetic Technique and Quality of Recovery After Cesarean Delivery
The goal of this prospective observational study is to evaluate whether the type of neuraxial anesthesia is associated with postoperative quality of recovery in adult women undergoing cesarean delivery.
- Conditions
- Ceserean Section, Obstetric Quality of Recovery, Neuraxial Anesthesia
- Trial name
- NCT07896733
- Testing
- Spinal anesthesia (heavy bupivacaine), epidural anesthesia, combine spinal epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Marmara University
Anesthesia Morbidity, Procedural Hypotension
Shock Index, Modified Shock Index and Age-related Shock Index for Predicting Post-spinal Hypotension in Elderly Patients
Aim of this prospective observational study is to investigate whether shock index(SI), modified shock index(MSI) and age related shock index(ASI) have any predictive value in predicting post-spinal hypotension which may develop…
- Conditions
- Anesthesia Morbidity, Procedural Hypotension, Intraoperative Hypotension, Geriatrics
- Trial name
- NCT04483765
- Testing
- spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ankara City Hospital Bilkent
Arthropathy of Hip, Hip Osteoarthritis
Comparison of Spinal Anesthesia With Intrathecal Morphine Versus PENG Block With or Without Dexamethasone in Hip Arthroplasty
The goal of this clinical trial is to learn which of three regional anesthesia approaches provides better pain relief and safety for older adults having planned hip replacement surgery.
- Trial name
- THA (NCT07584200)
- Testing
- Intrathecal Morphine, Pericapsular Nerve Group Block, Dexamethasone
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Caesarian Section
Comparison of Successful Spinal Needle Insertion Between Obese and Non-obese Pregnant Women
The study aimed to compare successful spinal needle insertion between obese and non-obese pregnant women in crossed leg sitting position undergoing cesarean section
- Trial name
- NCT03054233
- Testing
- Crossed leg sitting position
- Where
- 2 sites in Indonesia
- Volunteers
- 136 people
- Sponsor
- Universitas Indonesia
Spinal Anesthesia in Elderly Patients
Fractionated Spinal Anesthesia With Combined Isobaric and Hyperbaric Bupivacaine for Elderly Hip Fracture Patients
This prospective randomized controlled study will be conducted to compare the effect of fractionated SA using isobaric and hyperbaric bupivacaine with fractionated SA using hyperbaric bupivacaine and the conventional SA on…
- Trial name
- NCT07288996
- Testing
- Fractionated SA with isobaric and hyperbaric bupivacaine, Fractionated SA with hyperbaric bupivacaine, Conventional SA group
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Tanta University
Spinal Anesthesia, Hip Fractures
Peri-Capsular Nerve Group and Supra Inguinal Fascia Iliaca BLOCK for Analgesia and Ease of Positioning During Neuraxial Anesthesia in Hip Fracture Patients
Severe pain associated with fractured hip often results in difficulty during positioning for spinal anesthesia (SA). Among many regional analgesic techniques, the fascia iliaca compartment block (FICB) is popular among…
- Trial name
- NCT05987254
- Testing
- suprainguinal fascia iliaca block, pericapsular nerve group block
- Where
- 3 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Intraoperative Hypotension
The Use of Integrated Pulmonary Index During Cesarean Section Under Spinal Anesthesia
Postspinal hypotension (PSH) is a common side effect with an incidence of 15.3 to 33% that can result in organ hypoperfusion and ischemic events.
- Trial name
- NCT05237856
- Testing
- Capnometry Monitorization
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Selcuk University
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