Clinical trials: Subarachnoid Block
Shivering Caused by Spinal Anesthesia
Effect of Continuous Phenylephrine Infusion on Preventing Shivering After Spinal Anesthesia in Cesarean Section
This study aims to evaluate the effectiveness of continuous phenylephrine infusion at 50 mcg/min in preventing shivering after spinal anesthesia in cesarean section.
- Trial name
- NCT07663149
- Testing
- Phenylephrine
- Where
- Indonesia
- Volunteers
- 108 people
- Sponsor
- Universitas Indonesia
Obstetric Anesthesia Problems
Preloading to Prevent Hypotension During Cesarean Section
Whether the usage of non-invasive arterial blood pressure monitor to guide fluid therapy in caesarean section can effectively reduce the incidence of hypotension and fetal complications.
- Trial name
- NCT03013140
- Testing
- Fluid therapy, Spinal anaesthesia
- Where
- Taiwan
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lower Extremity Fracture
Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
A study to compare between intravenous atropine and glycopyrrolate in preventing spinal anesthesia induced hypotension in patients undergoing major lower limb orthopedic surgeries.
- Trial name
- NCT03580889
- Testing
- Atropine, Glycopyrrolate, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Nepal
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Ultrasound, Spinal Anaesthesia
Should Anaesthesiologists Be Taught to Perform Ultrasound-- Assisted Neuraxial Access in Spinal Anaesthesia?
Neuraxial blockade is commonly performed using a manual palpation technique, but the procedure can be challenging, particularly in patients with high body mass index, pregnancy, or spinal deformities.
- Conditions
- Ultrasound, Spinal Anaesthesia, Simulation Based Medical Education
- Trial name
- NCT07426679
- Testing
- Ultrasound-assisted spinal anaesthesia, Control group
- Where
- 2 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- University of Southern Denmark
Cesarean Section
TAP Block With Intrathecal Fentanyl vs. Intrathecal Morphine in Cesarean Delivery
This noninferiority study aims to determine whether transversus abdominis plane (TAP) block with intrathecal fentanyl could provide a noninferior analgesia compared with intrathecal morphine after cesarean delivery under spinal…
- Trial name
- NCT04824274
- Testing
- fentanyl, morphine, Transversus abdominis plane block
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Pre-Eclampsia, Cesarean Section
Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery
This study will compare between combination of colloids/crystalloids and crystalloids in women with preeclampsia undergoing elective cesarean delivery under spinal anesthesia
- Trial name
- NCT03252496
- Testing
- Spinal Anesthesia, Intrathecal Bupivacaine, Intrathecal Fentanyl
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Mansoura University
Spinal Hypotension
Pilot Study of Real-Time Blood Pressure Decision Support During Cesarean Delivery Under Spinal Anesthesia
This single-center, open-label pilot study evaluates a clinician-facing decision-support algorithm that displays real-time forecasts of maternal mean arterial pressure (MAP), a measure of blood pressure, during elective cesarean…
- Trial name
- NCT07534774
- Testing
- ARX Decision-Support Display
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Postoperative Pain
Comparison of Pain Relief Duration With Dexmedetomidine Versus Fentanyl Added to Spinal Anesthesia in Patients Undergoing Lower Limb Orthopedic Surgery
The goal of this randomized clinical trial is to compare how long effective pain relief lasts when dexmedetomidine or fentanyl is added to hyperbaric bupivacaine during spinal anesthesia for lower limb orthopedic surgery.
- Trial name
- NCT07770542
- Testing
- Dexmedetomidine & Bupivacaine., fentanyl and bupivacaine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Allama Iqbal Teaching Hospital
Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV)
Dexamethasone to Prevent Side Effects of Spinal Anesthesia in Cesarean Delivery
The goal of this clinical trial is to evaluate the effectiveness of intravenous dexamethasone in preventing adverse effects of spinal anesthesia and prolonging postoperative analgesia in parturients undergoing elective cesarean…
- Conditions
- Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV), Pain, Postoperative
- Trial name
- NCT07615595
- Testing
- Dexamethasone
- Where
- Vietnam
- Volunteers
- 176 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Cesarean Section, Post Operative Pain
Ilioinguinal Iliohypogastric Nerve Block as Adjunct to Spinal Anesthesia for Cesarean Section
The aim of the present controlled randomized study is to compare between ilioinguinal/iliohypogastric nerve block (IINB) and morphine as adjuncts to spinal anesthesia for cesarean section regarding quality of post-operative…
- Trial name
- NCT06108895
- Testing
- ilio-inguinal/ilio-hypogastric nerve block (IINB), intrathecal morphine
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Hemorrhoid, Peri Anal Fistula
Discharge Conditions of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl
In this prospective randomized study the investigators aimed to investigate difference of the duration of spinal anesthesia, discharge times and efficacy between low dose heavy Prilocaine-Fentanyl and heavy Bupivacaine-Fentanyl…
- Trial name
- NCT01880775
- Testing
- Prilocaine, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Teaching and Research Hospital
Frailty, Spinal Anesthesia
Frailty and Spinal Anesthesia-Induced Hypotension in Elderly
60 patients aged 65 and older with ASA I-III physical status undergoing elective surgery under spinal anesthesia will be included in the study.
- Trial name
- NCT06757439
- Volunteers
- 60 people
- Sponsor
- Selcuk University
Pregnant Women, Pain
Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine 2% for Cesarean Section Under Spinal Anesthesia
Over the past 15 years, cesarean delivery is most commonly performed under spinal anesthesia using hyperbaric bupivacaine which provides an adequate sensory and motor block.
- Conditions
- Pregnant Women, Pain, Hypotension
- Trial name
- NCT02973048
- Testing
- Hyperbaric bupivacaine, Hyperbaric prilocaine
- Where
- 2 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Post-Dural Puncture Headache
Effect of Altitude on Postdural Puncture Headache After Caesarean Delivery
The aim of this study is to examine the effects of altitude (high altitude versus low altitude) on incidence and severity of postural puncture headache (PDPH) following spinal anaesthesia for caesarean delivery.
- Trial name
- NCT05804448
- Where
- 2 sites in Nepal
- Volunteers
- 292 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Anesthesia
Postdural Puncture Headache Relief With Aminophylline and SPGB
The purpose of the study is to compare Sphenopalatine ganglion block (SPGB) and aminophylline in the efficacy and safety management of PDPH.
- Trial name
- NCT05552404
- Testing
- conservative therapy, Aminophylline, trans nasal sphenopalatine ganglion block
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hip Fractures, Spinal Anesthesia
The Effect of Spinal Column Flexion on Unilaterality of Spinal Anesthesia
The effect of two different positions on spinal anesthesia in hip fracture surgery
- Trial name
- NCT06293404
- Testing
- Bupivacain
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Caesarian Section
Comparison of Successful Spinal Needle Insertion Between Obese and Non-obese Pregnant Women
The study aimed to compare successful spinal needle insertion between obese and non-obese pregnant women in crossed leg sitting position undergoing cesarean section
- Trial name
- NCT03054233
- Testing
- Crossed leg sitting position
- Where
- 2 sites in Indonesia
- Volunteers
- 136 people
- Sponsor
- Universitas Indonesia
Post-Dural Puncture Headache, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Predictive Value of ONSD and NIRS for PDPH
Currently, there is no reliable and effective method available in clinical practice to predict the development of PDPH. Early prediction and prevention of PDPH would reduce the incidence of postoperative complications, thereby…
- Trial name
- NCT07729449
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ordu University
Penile Length, Spinal Anesthesia
Penile Length After Spinal Anesthesia vs General Anesthesia for Cystoscope in Adults
This research aimed to explore the impact of spinal and general anesthesia on penile length during surgery.
- Conditions
- Penile Length, Spinal Anesthesia, General Anesthesia, Cystoscope
- Trial name
- NCT07580807
- Testing
- Spinal anesthesia, General anesthesia
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Tanta University
Pregnant Women
Estimation of the Effective Dose (ED) 95 of Intrathecal Hyperbaric Prilocaine 2% for Scheduled Cesarean Delivery.
Prilocaine is a local anesthetic drug which as an intermediate duration of action shorter than bupivacaine 0,5% that is usually used for spinal anesthesia in scheduled cesarean section.
- Trial name
- NCT03607916
- Testing
- Hyperbaric prilocaine 2%, Morphine
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
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