Clinical trials: Subarachnoid Block
Arthropathy of Hip, Arthropathy of Knee
Evaluation of the Duration of Bupivacaine Spinal Block in Orthopedic Procedures With and Without Epinephrine Wash
Bupivacaine spinal is commonly performed as the primary anesthetic for orthopedic procedures. In some cases the duration of the block is inadequate. An epinephrine wash is sometimes performed to prolong the duration of the block.
- Trial name
- NCT02619409
- Testing
- Bupivacaine Only, EPI25, EPI50 group
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Recovery Period, Anesthesia
Comparing Spinal Anesthesia With 1% Chloroprocaine Versus 1% Mepivacaine in Patients Undergoing Outpatient Primary Total Knee Arthroplasty
This study or clinical trial looking to compare 2 types of freezing medications injected into the spinal fluid at the lower back between the vertebrae in patients going to have total knee replacement surgery to check for early…
- Trial name
- NCT07239999
- Testing
- Mepivacaine Injection, Chloroprocaine Injection
- Volunteers
- 170 people
- Sponsor
- Nova Scotia Health Authority
Intraoperative Complications
Liberal Versus Restrictive Fluid Protocols in Adults
The term acute kidney injury (AKI) is used to describe a rapid deterioration (hours to days) of renal function. This rapid deterioration leads to accumulation of plasma waste products, such as urea and creatinine.
- Trial name
- NCT03697330
- Testing
- Ringer lactate
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain, Postoperative, Analgesia
Comparison of Postoperative Analgesic Efficacy of Caudal Block Versus Spinal Block With Levobupivacaine for Inguinal Hernia in Children
Neuraxial analgesia may improve postoperative outcomes for high-risk children who are susceptible to respiratory complications (e.g. post-operative apnea).
- Trial name
- NCT05117281
- Testing
- Levobupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Spinal Anesthesia
Impact of Real-Time Ultrasound-Guided Spinal Anesthesia Versus Landmark-Guided Spinal Anesthesia on Anesthesia Procedural Time
Intraspinal anesthesia, traceable to the late 19th century, involves injecting local anesthetics into the spinal canal to block nerve signals, relieving pain and relaxing muscles for surgery.
- Trial name
- NCT06656793
- Where
- China
- Volunteers
- 3,597 people
- Sponsor
- Tongji Hospital
Analgesia, Analgesics, Opioid
Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study
The proposed pilot study is a prospective, randomized, controlled, double-blind, single-center pilot study.The aim of this pilot project is to evaluate the feasibility of a phase III study on the use of dexmedetomidine in…
- Conditions
- Analgesia, Analgesics, Opioid, Anesthesia, Obstetrical, Anesthesia, Spinal
- Trial name
- NCT05099055
- Testing
- Dexmedetomidine 0.004 MG/ML [Precedex], Opioids
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- St. Justine's Hospital
Regional Anesthesia, SARS-CoV2 Infection
SARS-CoV-2 PANDEMIC AND FAILED SPINAL ANESTHESIA
The investigators used a retrospective review of 251 SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) positive patients' cesarean section anesthesia to determine the rate of failed spinal anesthesia, management…
- Trial name
- NCT05067985
- Testing
- covid 19 spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 251 people
- Sponsor
- Ankara City Hospital Bilkent
Post-Dural Puncture Headache
Optic Nerve Sheath Diameter in Postspinal Headache
This study aims to investigate the relationship between spinal needle size and optic nerve sheath diameter (ONSD) in patients who develop post-dural puncture headache (PDPH) after spinal anesthesia.
- Trial name
- PDPHPatients (NCT06957899)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Konya City Hospital
Spinal Anesthesia-Induced Hypotension, Preeclampsia
Investigation of the Role of Internal Jugular Vein Collapsibility Index in Predicting Spinal Anesthesia-Induced Hypotension in Preeclamptic Parturients
This prospective, single-center observational study aims to evaluate the predictive value of the internal jugular vein collapsibility index (IJVCI) for spinal anesthesia-associated hypotension in preeclamptic parturients…
- Conditions
- Spinal Anesthesia-Induced Hypotension, Preeclampsia, Cesarean Section
- Trial name
- NCT07496788
- Testing
- Internal Jugular Vein Collapsibility Index Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ankara City Hospital Bilkent
Serum Bupivacaine Level, Periarticular Block
Plasma Concentrations of Bupivacaine After Peri-articular Injection in Total Knee Arthroplasty
Patients with knee arthroplasty usually performed under spinal anesthesia with a single-shot femoral nerve block and periarticular block, so we would like to know the plasma concentration of bupivacaine in these patients.
- Conditions
- Serum Bupivacaine Level, Periarticular Block, Total Knee Arthroplasty
- Trial name
- NCT01636869
- Testing
- Bupivacaine
- Where
- Thailand
- Volunteers
- 43 people
- Sponsor
- Mahidol University
Neonatal Hypoxia and Asphyxia
Can Shorter Time Intervals Help the Baby Survive the Triad Effect of Maternal Hypertension, Caesarean Section and Spinal Anesthesia?
Patients were classified into two equal groups using the presence or absence of hypertension during pregnancy into: hypertensive group (BP>140/90) and normotensive group (BP≤140/90.
- Trial name
- NCT03461913
- Testing
- Cesarean section
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality
Transthoracic Echocardiography of Inferior Vena Cava Before Spinal Anesthesia Can Predict Hypotension
Study Protocol: Outcome Measurements Primary Outcome The main outcome will be the preoperative performance of the dIVCmax/IVCCI ratio to foresee the incidence of hypotension after spinal anesthesia in a greater extent to that of…
- Conditions
- Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality, Intraoperative Complications
- Trial name
- NCT03266250
- Testing
- spinal anesthesia
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Subarachnoid Hemorrhage
Stellate Ganglion Block as Adjuvant Therapy to ca Channel Blocker
Aim of work: To evaluate the effect of stellate ganglion block in prevention of cerebrovascular spasm in traumatic subarachnoid hemorrhage Primary outcome: Asses changes of cerebral blood flow velocity by Trans cranial Doppler.
- Trial name
- NCT04100824
- Testing
- stellate ganglion block by transcranial doppler, Nimodipine
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain, Acute
Evaluation of Pericapsular Nerve Group Block on Positioning Pain for Spinal Anesthesia in Hip Fracture Patients
The purpose of this study is to evaluate of analgesic effects of pericapsullar nerve group block which is performed preoperatively to assist positioning patients for performance of spinal anesthesia.
- Trial name
- NCT04871061
- Testing
- PENG Block, Conventional opioid analgesia (Fentanyl)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cigli Regional Training Hospital
Shivering, Spinal Anesthesia
Post Operative Shivering Following Anesthesia
The aim of this study is to compare the efficacy of magnesium sulphate, ondansetron, and dexmedetomidine in managing post-spinal anesthesia shivering.
- Trial name
- NCT07377903
- Testing
- Dexmedetomidin, Mg (magnesium sulfate), Ondansetron 8 mg
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Neuromuscular Blockade
Popliteal Approach to Sciatic Nerve Block Is Not Inferior to Infragluteal Approach
Study Hypothesis The investigators approach to demonstrate noninferiority of analgesia provided by popliteal block in TKA surgery will be based on a hypothesis of absence of a clinically significant difference in pain visual…
- Trial name
- NCT03410888
- Testing
- Popliteal approach, Infragluteal approach
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University Health Network, Toronto
Femur Fracture, Peripheral Nerve Block
Peripheral Nerve Blocks vs Selective Spinal Anesthesia in Patients With Femur Fracture
Proximal Femur Fractures (PFF) represent one of the most common orthopedic injuries worldwide, affecting especially elderly patients with potentially disabling outcomes and a marked impairment of quality of life.
- Conditions
- Femur Fracture, Peripheral Nerve Block, Spinal Anesthesia
- Trial name
- NCT06155903
- Testing
- Selective Spinal Anesthesia, Peripheral nerve blocks, Anesthesiological mixtures (Spinal anesthesia)
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Federico II University
Intubation Skill, Laryngeal Mask Airway Insertion Skill
Evaluation of Learning Curve of Manual Skills in Anesthesia Residents
To determine number of cases need to perform in new anesthesia residents to be proficient in manual skills.
- Conditions
- Intubation Skill, Laryngeal Mask Airway Insertion Skill, Spinal Anesthesia Skill, Epidural Anesthesia Skill
- Trial name
- NCT01236183
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Lumbar Disc Herniation, Lumbar Disc Disease
GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries
The purpose of this study is to determine the optimal anesthetic routine for lumbar decompression surgery. General Anesthesia is the standard of care in spine surgery.
- Conditions
- Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
- Trial name
- NCT05444751
- Testing
- General anesthetic, SA + ESP
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Fluid Hypovolemia, Cerebrospinal
Assessment of Ultrasonographic Measurement of Inferior Vena Cava Collapsibility Index in Prediction of Hypotension Associated With Tourniquet Release in Total Knee Replacement Surgeries Under Spinal Anesthesia
Administration of intravascular fluids is one of the methods to prevent SA-induced hypotension, but empirical intraoperative volume repletion carries the risk of fluid overload during elective surgery.
- Trial name
- NCT05076929
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
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