Clinical trials: Subarachnoid Block
Arthritis Knee, Magnesium Sulfate
Magnesium and Postoperative Pain
With ongoing advancements in healthcare leading to prolonged life expectancy, orthopedic surgeries are increasingly performed in elderly patients.
- Conditions
- Arthritis Knee, Magnesium Sulfate, Dexmedetomidine
- Trial name
- NCT03253224
- Testing
- Magnesium Sulfate, Normal saline
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
Spinal Anesthesia, Ultrasound Assistance
Spinal Anesthesia Using Ultrasound Assistance Versus Conventional Palpation in Morbidly Obese Patients
The aim of this study is to compare the paramedian approach for spinal anesthesia using ultrasound assistance (USAS) versus conventional palpation in morbidly obese patients undergoing elective surgeries.
- Conditions
- Spinal Anesthesia, Ultrasound Assistance, Obesity, Morbid
- Trial name
- NCT05240846
- Testing
- Paramedian conventional palpation group, Ultrasound assistance paramedian spinal group
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Kafrelsheikh University
Hypotension, Spinal Anesthesia
Pupillary Light Reflex to Predict Post-Spinal Hypotension in Elective Cesarean Delivery
This prospective observational cohort study investigates whether pre-anesthetic pupillary light reflex (PLR) parameters can predict the risk of hypotension following spinal anesthesia in women undergoing elective cesarean…
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Delivery
- Trial name
- NCT07678723
- Testing
- Not applicable- observational study
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Gynecologic Laparoscopic Surgery
Intrathecal Mg in Gynecologic Laparoscopic Surgeries.
The investigators aim to investigate the differences between intrathecal Bupivacaine + Mg sulfate in spinal anesthesia versus Bupivacaine on surgeon satisfaction and postoperative pain in gynecologic laparoscopic surgeries.
- Trial name
- NCT02671227
- Testing
- intrathecal Mg sulfate., intrathecal bupivacaine 15 mg.
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hypotension After Spinal Anesthesia
ED50/ED90 of Phenylephrine Infusion for Preventing Spinal Anesthesia-Induced Hypotension: Supine vs Left-Tilt 15°
The purpose of this study is to determine the 50% and 90% effective doses (ED50 and ED90) of prophylactic phenylephrine infusion for preventing spinal anesthesia-induced hypotension during elective cesarean delivery, in the…
- Trial name
- NCT07824713
- Testing
- Phenylephrine hydrochloride infusion
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University People's Hospital
Difference in Reduction in Visual Analogue Score at 30 Minutes
Pericapsular Nerve Block Versus Propofol During Hip Fractures Surgery
The study will compare the efficacy of Pericapsular nerve group block (PENG) versus low dose Propofol for the achievement of painless sitting position before spinal anesthesia in patients undergoing repair of Hip fractures.
- Trial name
- NCT06631118
- Testing
- pericapsular nerve group block for group A,low dose intravenous Propofol [0.7mg/kg] over 30 seconds for group B
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Hypotension
ET 50 for Post Caesarean Section Spinal Hypotension
Hypotension is extremely common after induction of spinal anesthesia for cesarean delivery. Anesthetic blockade of the sympathetic outflow of the spinal cord causes vasodilation, and is one cause of this hypotension.
- Trial name
- ET-50 (NCT01561274)
- Testing
- 2 ml bupivacaine, 1.5 ml bupivicaine.
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Hip Fractures
MED90 of Ropivacaine for Peripheral Nerve Block on Posture-evoked Pain in Spinal Anesthesia Positioning
This study aims to determine the minimum effective dose of ropivacaine for peripheral nerve block on posture-evoked pain for spinal anesthesia in elderly patients with hip fracture.
- Trial name
- NCT04705974
- Testing
- Fascia iliaca block, Femoral nerve block, Pericapsular nerve group block (PENG block)
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Huazhong University of Science and Technology
Cardiac Output, Low
Cardiac Index Changes With Ephedrine, Phenylephrine, Ondansetron and Norepinephrine During Spinal Anesthesia
The purpose of the study is to evaluate the cardiac output changes after an intravenous bolus of ephedrine, phenylephrine, ondansetron or norepinephrine during a spinal anesthetic for a cesarean delivery.
- Trial name
- EPhON (NCT03421860)
- Testing
- cardiac output changes with "ephedrine", cardiac output changes with "phenylephrine", cardiac output changes with "ondansetron"
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Propofol, Dexmedetomidine
Impact of Two Different Types of Sedation on ICEB
The QT interval is a measure of the combination of cardiac depolarization and repolarization as it encompasses both the QRS complex and the J-T interval.
- Conditions
- Propofol, Dexmedetomidine, Electrophysiological Balance Index, QT Interval, Variation in
- Trial name
- NCT05757063
- Testing
- Sedation with propofol, sedation with dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara City Hospital Bilkent
Pain, Headache
The Association Between Pain Catastrophizing Scale Score and Postspinal Headache
This study is aimed to elucidate the association between Pain Catastrophizing Scale Score and Postspinal Headache in Patients Underwent Cesarean Section With Spinal Anesthesia.
- Trial name
- NCT02727244
- Testing
- urgent or elective cesarean section
- Volunteers
- 300 people
- Sponsor
- Tokat Gaziosmanpasa University
Sedation During Lower Extremity Surgery Under Spinal Anesthesia
Remimazolam Concentration and Sedation Depth During Lower Extremity Surgery Under Spinal Anesthesia
This study will examine how the amount of remimazolam predicted to reach its site of action relates to the depth of sedation during lower extremity surgery under spinal anesthesia.
- Trial name
- NCT07863063
- Testing
- Remimazolam
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Anesthesia
Pre-procedural Ultrasound Techniques Versus Conventional Landmark Technique of Spinal Anesthesia in Elderly Patients
Traditionally, spinal anesthesia is performed using the palpation of bony landmark to identify the level and point of entry of the spinal needle.
- Trial name
- NCT02658058
- Testing
- Landmark technique, Ultrasound-guided paramedian technique, Ultrasound-guided midline technique
- Where
- Lebanon
- Volunteers
- 180 people
- Sponsor
- American University of Beirut Medical Center
Spinal Anesthesia
Effect of Vasopressors on Spinal Anaesthesia Induced Hypotension
160 pregnant patients will be enrolled in this study. Participants will divide in to 4 groups. Spinal anaesthesia will perform with 5% marcain heavy 2 ml+20 microgram fentanyl to the all patients.
- Trial name
- NCT03163914
- Testing
- Epinephrine, Norepinephrine, Phenylephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Total Knee Arthroplasty in Geriatric Patients, Spinal Anesthesia
Isobaric Spinal Ropivacaine Versus Hyperbaric Spinal Bupivacaine in Total Knee Arthroplasty in Geriatric Patients
The purpose of this study is to evaluate the efficacy and safety of spinal anesthesia with isobaric ropivacaine, compared with hyperbaric bupivacaine in geriatric patients undergoing lower limb orthopedic surgery.
- Trial name
- NCT02764723
- Testing
- Hyperbaric bupivacaine, Isobaric ropivacaine
- Volunteers
- 52 people
- Sponsor
- Mohamed Sayed Mohamed Abbas
Anxiety, Surgery
Does Showing Video Information About Spinal Anesthesia Relieves Patient Anxiety?
Our primary aim is to compare the effect of pre-operative multimedia video information on perioperative anxiety and hemodynamic parameters.
- Conditions
- Anxiety, Surgery, Spinal Anesthesia
- Trial name
- NCT04387487
- Testing
- Multimedia video information
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chitwan Medical College
Knee Osteoarthritis
Investigation of the Effect of Proximal and Distal Adductor Canal Block in Knee Replacement Surgery
to investigate the effect of adductor canal block applied with two different approaches in the treatment of pain after TKA surgery on pain control and functional mobility.
- Trial name
- NCT06188806
- Testing
- ADDUKTOR CANAL BLOCK, CONTROL GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Umraniye Education and Research Hospital
Cesarean Delivery
An Observational Study Measuring in a Non-invasive Approach the Nociception Level Index and Its Association With Pain and Anxieiy Perception Evaluated by Questionnaires, in Awake Women During Elective Cesarean Delivery Under Spinal Anesthesiaanxiety
The Nociception Level (NOL) Index is a multiparametric, non-invasive monitor that objectively assesses nociception by integrating several autonomic physiological signals.
- Trial name
- NCT07726316
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Michael Grach
Cardiac Output
The Effect of Ondansetron on Cardiac Output in Elective Cesarean Deliveries
Ondansetron is a medication routinely given to mothers having cesarean deliveries to help prevent and treat nausea and vomiting.
- Trial name
- NCT01841606
- Testing
- Ondansetron, Normal saline
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Total Joint Arthroplasty
Utility of Indwelling Catheter in Orthopaedic Patients Receiving Spinal Anesthesia
A study measuring utility of indwelling bladder catheter placement in orthopaedic surgical patients receiving spinal anesthesia. Study will track clinical outcomes, patient satisfaction and cost efficacy.
- Trial name
- NCT01577823
- Testing
- Foley Catheter
- Where
- United States
- Sponsor
- Rothman Institute Orthopaedics
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