Clinical trials: Subarachnoid Hemorrhage, Spontaneous
Subarachnoid Aneurysm Hemorrhage
Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
Despite its lower incidence rate within the stroke population and tendency to affect younger individuals, SAH carries the highest risk of PSCI.
- Trial name
- NCT07588997
- Testing
- early motor-cognitive integrated training (e-MCIT), Early mobilization
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Taiwan University Hospital
Traumatic Intracranial Subarachnoid Hemorrhage
Appropriateness of Methodist Health System(MHS) Inter-facility Transfers of Traumatic Intracranial Subarachnoid Hemorrhage and Spontaneous Bleeds for Level-1 Advanced Surgical Intervention
Brain injuries are common and challenging problems faced by emergency physicians. These diagnoses may include traumatic intracerebral hemorrhage, subarachnoid hemorrhage, ruptured cerebral aneurysms, unruptured cerebral…
- Trial name
- NCT06136078
- Testing
- rate of appropriate and inappropriate transfers from Methodist interfacility transfers
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Methodist Health System
Spontaneous Subarachnoid Hemorrhage
The Bilirubin Levels in Cerebrospinal Fluid of Spontaneous Subarachnoid Hemorrhage Patients
According to Morgan et. al. (J Neurosurg 101:1026-1029, 2004): bilirubin as a cerebrospinal fluid marker of sentinel subarachnoid hemorrhage: a preliminary report in pigs, we're going to test the hypothesis in the cerebrospinal…
- Trial name
- NCT00173095
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Subarachnoid Hemorrhage, Spontaneous
Determinants of Rehabilitation Outcomes in Survivors of Primary Subarachnoid Haemorrhage
A retrospective, observational single centre study of electronic medical records of discharged patients who were admitted to from 1 January 2015 to 31 December 2018.
- Trial name
- DETERMINESAH (NCT04357626)
- Testing
- Inpatient Rehabilitation
- Where
- 2 sites in Singapore
- Volunteers
- 114 people
- Sponsor
- Tan Tock Seng Hospital
Hyperventilation, Aneurysmal Subarachnoid Hemorrhage
Drug Intervention of Spontaneous Hyperventilation in Patients With Aneurysmal Subarachnoid Hemorrhage
Although spontaneous hyperventilation patients with aneurysmal subarachnoid hemorrhage closely associated with poor outcomes, the standard therapy remains unavailable.
- Conditions
- Hyperventilation, Aneurysmal Subarachnoid Hemorrhage, Cerebral Blood Flow
- Trial name
- NCT04940273
- Testing
- Remifentanil Injection [Ultiva]
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Subarachnoid Hemorrhage, Aneurysmal, Headache
BLOCK-SAH - PPF-Block for Post-SAH Headache
BLOCK-SAH is a phase II, multicenter, randomized, double-blinded, placebo-controlled clinical trial with a sequential parallel comparison design (SPCD) of bilateral pterygopalatine fossa (PPF) injections with 20mg ropivacaine +…
- Trial name
- BLOCK-SAH (NCT06008795)
- Testing
- Pterygopalatine Fossa Nerve Block with Ropivacaine and Dexamethasone
- Where
- 13 sites in United States
- Volunteers
- 195 people
- Sponsor
- University of Florida
Subarachnoid Hemorrhage
Auricular VNS Following Subarachnoid Hemorrhage
This study will evaluate whether non-invasive auricular vagal nerve stimulation lowers inflammatory markers, and improves outcomes following spontaneous subarachnoid hemorrhage.
- Trial name
- NCT04557618
- Testing
- Auricular Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Anna Huguenard
Spontaneous Subarachnoid Hemorrhage
Nursing Risk Management in Emergency SAH Surgery Using Healthcare Failure Mode and Effect Analysis(HFMEA)
The investigators are testing whether a new nurse-led safety program (HFMEA) lowers problems during emergency brain-aneurysm surgery better than usual care.
- Trial name
- NCT07315048
- Testing
- HFMEA-based nursing-risk programme
- Where
- China
- Volunteers
- 156 people
- Sponsor
- West China Hospital
Intracranial Hemorrhages, Intracranial Hemorrhage, Hypertensive
Start or STop Anticoagulants Randomised Trial (SoSTART)
Primary research question: For adults surviving spontaneous (non-traumatic) symptomatic intracranial haemorrhage with persistent/paroxysmal atrial fibrillation/flutter (AF), does starting full treatment dose oral anticoagulation…
- Conditions
- Intracranial Hemorrhages, Intracranial Hemorrhage, Hypertensive, Subarachnoid Hemorrhage, Subdural Hematoma
- Trial name
- SoSTART (NCT03153150)
- Testing
- Apixaban, Rivaroxaban, Edoxaban
- Where
- 67 sites in United Kingdom
- Volunteers
- 203 people
- Sponsor
- University of Edinburgh
Subarachnoid Hemorrhage
Impact of Herniation on WFNS Grading in Spontaneous Subarachnoid Hemorrhage - a SWISS SOS Observational Trial
All patients (≥18 years) with a spontaneous SAH proven by computed tomography (CT), magnetic resonance imaging (MRI) or lumbar puncture will be considered for this trial.
- Trial name
- hWFNS (NCT02304328)
- Testing
- Clinical assessment
- Where
- 8 sites in Switzerland
- Volunteers
- 250 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Stroke, Intracerebral Haemorrhage
The Planetary Outcomes After Intracranial Haemorrhage Study
Over twelve million strokes occur worldwide every year, and stroke is the second most common cause of death globally. Strokes happen because blood supply to the brain is damaged.
- Conditions
- Stroke, Intracerebral Haemorrhage, Subarachnoid Haemorrhage (SAH)
- Trial name
- PLOT-ICH (NCT06731751)
- Testing
- Management of spontaneous intracranial haemorrhage
- Volunteers
- 1,000 people
- Sponsor
- University of Cambridge
Neurological Complication
Evaluation of the Safety and Efficacy of Parecoxib in Patients With Subarachnoid Hemorrhage
Because of the important role of inflammation in the pathophysiology of SAH, it was hypothesized that its pharmacological manipulation might improve the prognosis of patients.
- Trial name
- PARISAH (NCT06579274)
- Testing
- Parecoxib
- Where
- 4 sites in Czechia
- Volunteers
- 112 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Subarachnoid Hemorrhage, Lymphatic System Disorder
Radiological Changes of Glymphatic-meningeal Lymphatic Drainage System After Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is a common and extremely critical disease in neurosurgery. The mortality rate within 30 days of the onset of SAH is as high as 50%, and about 15% of SAH patients die without reaching the hospital.
- Conditions
- Subarachnoid Hemorrhage, Lymphatic System Disorder, Meningeal Lymphatic Vessels
- Trial name
- NCT06444438
- Testing
- subarachnoid hemorrhage
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Subarachnoid Hemorrhage
Constitution of Cerebrospinal Fluid and Blood Database/Specimen in Acute Stage of Subarachnoid Hemorrhage (aSAH) Patients
Neuropeptide Y (NPY) may play a major role in the pathophysiology of aneurysmal subarachnoid hemorrhage (aSAH). To investigate the correlation of NPY in cerebrospinal fluid (CSF) and blood (serum) and the neurological outcome in…
- Trial name
- NCT01292278
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Regensburg
Subarachnoid Hemorrhage
Prehospital Deaths From Spontaneous Subarachnoid Haemorrhages
In this study we aim to determine the incidence of fatal spontaneous subarachnoid haemorrhage outside hospital. Also, we aim to investigate these patient´s pattern of contact to the health care system immediately before their…
- Trial name
- NCT04052646
- Testing
- Medical condition: Subarachnoid hemorrhage
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Spontaneous Subarachnoid Hemorrhage
Time to Specialized Admission in Case of Severe Brain Haemorrhage.
Spontaneous subarachnoid haemorrhages (SAH) are a particularly severe type of stroke with a tendency to affect younger individuals than other types of stroke.
- Trial name
- NCT03786068
- Where
- Denmark
- Volunteers
- 262 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Spontaneous Subarachnoid Hemorrhage
A New Minimal-invasive Brain Tissue Probe Applying Near Infrared Spectroscopy
To assess the feasibility of a new brain tissue probe for multi-parameter neuromonitoring (NeMo Probe) and the accuracy of measurement values.
- Trial name
- NCT01801306
- Testing
- NeMo Probe
- Where
- Germany
- Volunteers
- 3 people
- Sponsor
- NeMoDevices AG
Brain Injuries, Intracranial Aneurysm
Hypopituitarism Following Traumatic Brain Injury or Spontaneous Subarachnoidal Haemorrhages
The purpose of this study is to assess the prevalence and predictors of pituitary dysfunction, as well as secondary out-come in patients with traumatic brain injury or spontaneous subarachnoidal haemorrhages.
- Trial name
- NCT00435006
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Subarachnoid Hemorrhage, Spontaneous
SFX-01 After Subarachnoid Haemorrhage
This is a Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of SFX-01 in Subarachnoid Haemorrhage, with exploratory evaluations of efficacy.
- Trial name
- SAS (NCT02614742)
- Testing
- SFX-01
- Where
- 3 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- Evgen Pharma
Traumatic Brain Injury, Intracerebral Hemorrhage
Clinical Decision Support System for Early Mobilization in the Neuro-ICU
This study aims to evaluate the feasibility, safety, and user acceptability of a tablet- and smartphone-based Clinical Decision Support System (CDSS) designed to guide early mobilization for patients with severe neurological…
- Conditions
- Traumatic Brain Injury, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Spontaneous, Acute Ischemic Stroke
- Trial name
- CDSS-EM-ICU (NCT07685145)
- Testing
- Clinical Decision Support System (CDSS) for Early Mobilization
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Taiwan University Hospital