Clinical trials: Subarachnoid Hemorrhage
Intracranial Hypertension, Traumatic Brain Injury
Invasive Versus Non-Invasive Intracranial Pressure-Guided Management in Neurosurgical Patients
Raised intracranial pressure (pressure inside the skull) is a serious complication for patients with brain injuries, strokes, or tumors. Managing this pressure is critical to prevent further brain damage.
- Conditions
- Intracranial Hypertension, Traumatic Brain Injury, Subarachnoid Haemorrhage (SAH), Intracerebral Haemorrhage
- Trial name
- NCT07853963
- Testing
- External Ventricular Drain (EVD) Placement and ICP Monitoring, Optic Nerve Sheath Diameter (ONSD) Ultrasonography
- Where
- Nepal
- Volunteers
- 40 people
- Sponsor
- Kathmandu Medical College and Teaching Hospital
Ruptured Aneurysm, Memory Deficits
Memory Training in Aneurysmal Subarachnoid Hemorrhage Patients
The study aim is to determine if periodic online cognitive exercises (Lumosity) improve memory function in ruptured cerebral aneurysm patients with disabling baseline memory deficits within the first 24 months after rupture.
- Conditions
- Ruptured Aneurysm, Memory Deficits, Subarachnoid Hemorrhage
- Trial name
- MASH (NCT02864940)
- Testing
- Lumosity, Crossword puzzle
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Rush University Medical Center
Subarachnoid Hemorrhage, Spontaneous, Subarachnoid Hemorrhage, Aneurysmal
Hemodynamic Instability of Patient With Spontaneous Subarachnoid Hemorrhage
The goal of this observational study is to learn about the role of biomarkers in spontaneous subarachnoid hemorrhage (sSAH) as predictors of severity of clinical outcome.
- Trial name
- HISAHES (NCT06218654)
- Testing
- biomarkers
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Subarachnoid Hemorrhage
Ventriculostomy in Subarachnoid Hemorrhage (SAH): Intracranial Pressure (ICP) Open or Not?
The purpose of this study is to explore two currently accepted methods of intracranial pressure (ICP) management through cerebral spinal fluid (CRF) drainage for patients diagnosed with subarachnoid hemorrhage (SAH).
- Trial name
- VISION 2 (NCT01169454)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Trauma and Emergency Care
Early Intravenous Magnesium Sulfate and Its Impact on Cerebral Vasospasm in Traumatic Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is a clinical phenomenon caused by the abrupt rupture and bleeding of blood vessels at the surface or base of the brain, which can occur for a number of reasons.
- Trial name
- NCT07252505
- Testing
- Magnesium Sulfate 10 MG/ML
- Volunteers
- 50 people
- Sponsor
- Assiut University
Subarachnoid Hemorrhage
French Validation of the SAHOT Outcome Scale After Subarachnoid Haemorrhage
Survivors of subarachnoid haemorrhage (SAH) frequently experience cognitive, psychological, physical and social sequelae, but no French-language instrument covers all these dimensions.
- Trial name
- SAHOT-FR (NCT07894666)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Subarachnoid Hemorrhage, Intracranial Aneurysm
Randomized, Double-blind, Placebo-controlled Trial to Investigate Safety and Efficacy of Cerebrolysin™ in Patients With Aneurysmal Subarachnoid Hemorrhage
This is a randomized, placebo-controlled, single-center clinical trial investigating the effectiveness of administrating intravenous Cerebrolysin™ (EVER NEURO Pharma, Austria), a preparation of low-molecular weight neurotrophic…
- Conditions
- Subarachnoid Hemorrhage, Intracranial Aneurysm, Delayed Cerebral Ischemia, Delayed Ischemic Neurological Deficit
- Trial name
- CESAR (NCT01787123)
- Testing
- Intravenous Cerebrolysin, Normal Saline
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Kwong Wah Hospital
Traumatic Brain Injury, Ischemic Stroke
Detection of Cerebral Ischemia With a Noninvasive Neurometabolic Optical Monitor
The goals of the project are to evaluate a noninvasive monitor of brain metabolism and blood flow in critically ill humans. If validated, such a reliable noninvasive brain blood flow and metabolism monitor, by allowing…
- Conditions
- Traumatic Brain Injury, Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage
- Trial name
- NNOM (NCT02983786)
- Testing
- Indocyanine Green
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Pennsylvania
Aneurysmal Subarachnoid Hemorrhage
Delayed Cerebral Ischaemia and Coagulation Alterations After Aneurysmal Subarachnoid Haemorrhage
Despite the advances in neurosurgical and -radiological techniques and intensive care, the mortality and morbidity rates in SAH have not changed in recent years.
- Trial name
- NCT03985176
- Testing
- ROTEM, EEG, bilateral compression ultrasound of the lower extremity veins
- Where
- Finland
- Volunteers
- 62 people
- Sponsor
- Tampere University Hospital