Clinical trials: Subdural Hematoma
Chronic Subdural Hematoma
Middle Meningeal Artery Embolization With Liquid Embolic Agent for Treatment of Chronic Subdural Hematoma
The study evaluates the clinical and imaging outcome of middle meningeal artery (MMA) embolization with liquid embolic agent for treatment of chronic subdural hematoma (CSDH)
- Trial name
- NCT04574843
- Testing
- Embolization of MMA
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Mashhad University of Medical Sciences
Chronic Subdural Hematoma
Endovascular Embolization of Chronic Subdural Hematomas After Surgery
Chronic subdural hematomas (CSH) are one of the most frequent pathologies in emergency neurosurgical practice. Standard therapy for symptomatic CSH is surgical drainage.
- Trial name
- ENCLOSURE (NCT05220826)
- Testing
- Post surgical embolization of middle meningeal artery with liquid embolic agents (ethylene vinyl alcohol copolymers as Onix, Squid, Phil or Libro)
- Where
- Spain
- Volunteers
- 280 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Chronic Subdural Hematoma
Neuroendoscopy-assisted Drainage Versus Burr Hole Drainage for Chronic Subdural Hematoma
Chronic subdural hematoma (CSDH) is a frequent condition in neurosurgery, leading to fluid accumulation between the meninges, brain compression, neurological dysfunction, and potentially herniation.
- Trial name
- URANUS (NCT07144423)
- Testing
- Endoscope-assisted hematoma drainage, Burr hole hematoma drainage
- Where
- 24 sites in China
- Volunteers
- 770 people
- Sponsor
- Beijing Tiantan Hospital
Chronic Subdural Hematoma
Tranexamic Acid Therapy For The Treatment of Subdural Hematomas
This Phase II randomized, placebo-controlled, double-blinded trial is the first step in our endeavor to improve the clinical outcomes of patients with chronic subdural hematomas (cSDH).
- Trial name
- NCT06718751
- Testing
- Tranexamic Acid 650 MG
- Volunteers
- 240 people
- Sponsor
- Baylor College of Medicine
Chronic Subdural Hematoma, Hemorrhage Brain
Microfabricated Microcatheter Advantages in Middle Meningeal Artery Embolization: an Early Experience at a Single Center
The purpose of this study is to evaluate the function of matched pair Aristotle 14 Guidewire and Plato Microcatheter in MMA embolization treatment for chronic subdural hematoma compared to surgeon's preference
- Trial name
- SCIENTIA (NCT07324551)
- Testing
- Matched pair Aristotle 14 guidewire and Plato 17 microcatheter, Surgeon combination preference
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Chronic Subdural Hematomas
Prospective MMA Embolization Registry
Chronic subdural hematoma (cSDH) is a common condition, particularly in older adults, that can substantially impair patients' quality of life, functional independence, and neurological well-being.
- Trial name
- PRO-EMMA (NCT07626671)
- Testing
- Middle Meningeal Artery Embolization
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Tbi, Intracranial Edema
Comparative Effectiveness of Family Problem-Solving Therapy (F-PST) for Adolescent TBI
Traumatic brain injury (TBI) is the most common cause of acquired disability in youth and a source of significant morbidity and family burden.
- Conditions
- Tbi, Intracranial Edema, Brain Edema, Craniocerebral Trauma
- Trial name
- NCT02368366
- Testing
- Therapist Guided Face to Face Family Problem Solving, Therapist Guided Online Family Problem Solving, Self-Guided Online Family Problem Solving
- Where
- 5 sites in United States
- Volunteers
- 151 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Subdural Hematoma, Subdural Hematoma
Prospective Study on the Use of Middle Meningeal Artery Embolization for Chronic Subdural Haematoma
Subdural haematoma is a common neurosurgical condition that results in different levels of neurological deficits in patients. It can be further classified into acute and chronic, which have different pathophysiology.
- Trial name
- NCT04500795
- Testing
- Middle meningeal artery embolization
- Where
- China
- Sponsor
- Chinese University of Hong Kong
Trauma
Acute Subdural Hematoma
This retrospective data repository will serve as a means to aggregate and analyze standard surgical interventions and Middle Meningeal Arteryembolization as suitable treatment options for Acute Subdural Hematoma.
- Trial name
- NCT07490197
- Testing
- Medical/Phenotype Data Collection Procedures & Data to be Collected
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Methodist Health System
Chronic Subdural Hematoma
Tranexamic Acid in Chronic Subdural Hematomas
BACKGROUND Chronic subdural hematoma (CSDH) is one of the most frequent reasons for cranial neurosurgical consult. There is no widely accepted medical treatment for CSDH.
- Trial name
- TRACS (NCT02568124)
- Testing
- Tranexamic Acid
- Where
- 3 sites in Canada
- Volunteers
- 130 people
- Sponsor
- Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Chronic Subdural Hematoma
Assessing Outcomes of Coil Embolization for Unilateral vs Bilateral Chronic Subdural Hematomas
This is a pragmatic, prospective, multicenter, randomized controlled trial with intention to treat analysis. In which subjects will receive either unilateral or bilateral middle meningeal artery (MMA) embolization using coils for…
- Trial name
- (COAST) (NCT07715656)
- Testing
- embolization therapy Bilateral, embolization therapy Unilateral
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Lahey Clinic
Chronic Subdural Hematoma
Effect and Safety Study of Atorvastatin to Treat Chronic Subdural Hematoma
To evaluate the clinic effects and security of oral administration of Atorvastatin on chronic subdural hematoma (CSDH).
- Trial name
- NCT02024373
- Testing
- Atorvastatin
- Where
- 31 sites in China
- Volunteers
- 200 people
- Sponsor
- Oriental Neurosurgery Evidence-Based-Study Team
Traumatic Brain Injury
Near-infrared Spectroscopy (NIRS) for Intracranial Hematoma Detection
Traumatic brain injury is a common neurosurgical emergency managed in all tertiary and secondary hospitals. Detecting the underlying pathology is a major challenge especially for surgical cases.
- Trial name
- NCT05189561
- Testing
- near-infrared scanner
- Where
- India
- Volunteers
- 208 people
- Sponsor
- National Institute of Mental Health and Neuro Sciences, India
Traumatic Brain Injury, Subdural Hematoma
Outcomes of Traumatic Intracranial Hemorrhage in the Elderly
This observational study aims to describe the clinical and radiological characteristics of older adults (aged 65 years and older) who experience traumatic bleeding in the brain, also known as traumatic intracranial hemorrhage.
- Conditions
- Traumatic Brain Injury, Subdural Hematoma, Epidural Hematoma
- Trial name
- NCT07822724
- Volunteers
- 50 people
- Sponsor
- Assiut University
Subdural Hematoma
Scalp Block Versus General Anesthesia in Patients Undergoing Evacuation of Subdural Hematoma Via Burr Hole
this study amis to compare between Scalp block versus general anesthesia in patients undergoing evacuation of subdural hematoma via burr hole.
- Trial name
- NCT07143799
- Testing
- Cisatracurium, scalp block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University
Hematoma, Subdural, Chronic
Tranexamic Acid to Prevent OpeRation in Chronic Subdural Hematoma
Rationale: Chronic subdural hematoma (cSDH) is a frequently occurring disease, occurring mainly in the elderly. Surgical evacuation is effective, but also associated with life-threatening risks.
- Trial name
- TORCH (NCT03582293)
- Testing
- Tranexamic Acid 500Mg Tablet
- Where
- Netherlands
- Volunteers
- 554 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Subarachnoid Hemorrhage, Intracranial Hemorrhage
Enteral Nutrition and Glycemic Variability Neurological Intensive Care Unit Study
Primary Objective: To determine the effects of a diabetes specific enteral formula compared to a standard formula supplemented with protein (isocaloric and isonitrogenous) on the mean blood glucose and glycemic variability in a…
- Conditions
- Subarachnoid Hemorrhage, Intracranial Hemorrhage, Ischemic Strokes, Subdural Hematoma
- Trial name
- ANUS1014 (NCT01463878)
- Testing
- Glycerna, Jevity - Control Diet
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Eastern Virginia Medical School