Clinical trials: Subgingival Plaque
Periodontal Diseases, Coronary Artery Disease
Quantification of NLRP3 (rs4612666) and CARD8 Gene (rs2043211) in Generalized Chronic Periodontitis Subjects
Quantification of NLRP3 (rs4612666) and CARD8 (rs20432111) will be analysed in the subgingival plaque and blood samples of generalized chronic periodontitis with and without coronary heart disease.
- Trial name
- NCT04127487
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Periodontal Diseases
Quantification of CD163 Inflammatory Biomarker in Chronic Periodontitis and Diabetic Subjects
The quantification of CD163 will be analysed in the subgingival plaque samples of generalized chronic periodontitis patients with and without diabetes mellitus.
- Trial name
- NCT03727035
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Periodontitis, Subgingival Plaque
Comparative Evaluation of Minimally Invasive Nonsurgical Periodontal Therapy Versus Conventional Subgingival Instrumentation
Background- The use of minimally invasive procedures has recently been advocated for the treatment of periodontitis, to minimize patient discomfort and maximize the healing potential.
- Trial name
- NCT05876455
- Testing
- Conventional Subgingival Instrumentation, minimally invasive non-surgical periodontal therapy
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Subgingival Plaque, GCF
Analysis of Stannous Fluoride in GCF and Subgingival Plaque
The amount of stannous fluoride in GCF and subgingival plaque samples will be analyzed.
- Trial name
- NCT03296657
- Testing
- stannous fluoride
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dental Plaque
Efficacy of Two Chlorhexidine Solutions to Control the Initial Subgingival Biofilm Formation
The aim of the study is to compare the effect of a suspension containing chlorhexidine and alcohol and another one containing clorhexidine with no alcohol in dynamic of the subgingival biofilm formation versus a Placebo…
- Trial name
- NCT02656251
- Testing
- 0.12% Clorhexidine with alcohol, 0.12% Clorhexidine without alcohol
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Periodontitis, Rheumatoid Arthritis
Effect of Nonsurgical Periodontal Therapy (NSPT) on Rheumatoid Arthritis Subjects With Periodontitis
Periodontitis (PD), a chronic inflammatory disease which results in irreversible attachment loss, bone destruction and, if left untreated, tooth loss.
- Trial name
- NCT05880303
- Testing
- Nonsurgical periodontal therapy
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- University of Malaya
Treatment of Periodontitis, Guided Biofilm Therapy
Comparison of Current Subgingival Debridement Methods
Our study aimed to compare the effectiveness of current subgingival debridement methods used in the treatment of Stage 1 and Stage 2 periodontitis patients, the aesthetic condition achieved after these treatments, and the pain…
- Conditions
- Treatment of Periodontitis, Guided Biofilm Therapy, Subgingival Plaque, Subgingival Debridement
- Trial name
- NCT06835452
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Hacettepe University
Subgingival Plaque
A Study to Evaluate Sampling Methods for Subgingival Plaque
To identify a sampling method for collecting subgingival plaque
- Trial name
- NCT02841839
- Testing
- Stannous Fluoride
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Periodontitis, Smoking Habit
Effects of Smoking on Clinical and Microbiological Response in Individuals With Periodontitis
This study aimed to compare the distribution of subgingival periodontal pathogens following non-surgical periodontal therapy in smoking and non-smoking people with periodontitis.
- Conditions
- Periodontitis, Smoking Habit, Subgingival Plaque
- Trial name
- NCT06383455
- Testing
- Non-surgical periodontal therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Trakya University
Dental Plaque
Efficacy of a Triclosan Formulation to Control the Initial Subgingival Biofilm Formation
The aim of the study is to compare the effect of a suspension containing Triclosan in dynamic of the subgingival biofilm formation versus a Placebo suspension.
- Trial name
- NCT02192060
- Testing
- Test - Using of a suspension containing Triclosan, Control - Using of a suspension without Triclosan
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Periodontal Diseases, Coronary Disease
Quantification of Micro-RNA 146-a in Chronic Periodontitis and Coronary Heart Disease Subjects
The expression and quantification of Micro-RNA 146-a, was analyzed in the subgingival plaque samples of generalized chronic periodontitis patients with and without coronary heart disease.
- Trial name
- NCT03721159
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Periodontitis, Subgingival Plaque
The Effect of Post-surgical Chlorhexidine Mouth Washing on the Sub-gingival Periodontal Microbiome A Pilot Study
Prospective applicants who conform with inclusion and exclusion criteria will be accepted into the study and sign a consent form.
- Trial name
- SUPEM1 (NCT05355740)
- Testing
- Corsodyl
- Where
- 2 sites in Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Dental Plaque, Bleeding of Subgingival Space
Antibacterial Photodynamic Therapy as an Adjunctive Treatment on Oral Hygiene in Elderly Persons
On average, the dental condition of elderly people is poor due to various reasons. The importance of oral health maintenance of the ageing population has been recognized by the World Health Organization (WHO), as oral health…
- Conditions
- Dental Plaque, Bleeding of Subgingival Space, Oral Complication
- Trial name
- NCT06576063
- Testing
- Lumoral Treatment, Standard oral hygiene methods
- Where
- 3 sites in Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Koite Health Oy
Gingivitis and Periodontal Diseases, Periodontitis
Association Between Periodontal Status and the Prevalence of Entamoeba Gingivalis and Trichomonas Tenax
This prospective observational study aims to investigate the prevalence and clinical significance of two oral protozoa, Entamoeba gingivalis and Trichomonas tenax, among patients attending the Bolu Abant İzzet Baysal University…
- Trial name
- NCT07551115
- Testing
- Clinical Periodontal Evaluation, Microscopic Examination of Oral Protozoa
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Miscarriage, Parodontitis
PERIodontal Disease, Microbiota and Miscarriage
Cross-sectional non-interventional observational pilot study recruiting women whom had repeated miscarriages (= at least 3 miscarriages).The information will be collected during a routine maintenance, complete oral clinical and…
- Trial name
- PERI2M (NCT06576622)
- Testing
- biological sampling
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse