Clinical trials: Subglottic Stenosis (SGS)
Idiopathic Subglottic Stenosis, Subglottic Stenosis (SGS)
A Phase I Evaluation of the Safety and Tolerability of Pirfenidone in Idiopathic Subglottic Stenosis
Idiopathic subglottic stenosis (iSGS) is a rare condition where scar tissue forms just below the vocal cords and in the upper windpipe, making the airway narrow.
- Trial name
- NCT07654517
- Testing
- Pirfenidone 267 MG [Esbriet]
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pain, Anxiety
Active vs. Passive VR During Office-based ENT Procedures
The purpose of this research is to evaluate whether active virtual reality reduces pain and anxiety more effectively than passive virtual reality during office-based ENT procedures.
- Conditions
- Pain, Anxiety, Chronic Rhinosinusitis (CRS), Nasal Obstruction
- Trial name
- NCT07599826
- Testing
- Passive virtual reality headset or goggles, Active virtual reality headset or goggles
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Cedars-Sinai Medical Center
Subglottic Stenosis (SGS)
Coblation Assisted Dilatation Versus Modified Maddern Procedure in Subglottic and Cervical Tracheal Stenosis
This study compares the effectiveness of Coblation-assisted endoscopic airway dilatation with the modified Maddern procedure-which involves endoscopic excision of scar tissue followed by buccal mucosal grafting-in patients with…
- Trial name
- NCT07303673
- Testing
- Coblation-assisted dilatation, Modified Maddern procedure
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Subglottic Stenosis (SGS), Pierre Robin Sequence (PRS)
Functional Modeling of the Pediatric Airway
The investigators hypothesize that a functional computational model that simulates the mechanical and aerodynamic behavior of the upper airway in children with Pierre Robin Sequence (PRS) and laryngeal lesions (e.g.
- Conditions
- Subglottic Stenosis (SGS), Pierre Robin Sequence (PRS), Micrognathia, Normal Controls From CT Scans of the Upper Airway
- Trial name
- NCT01690078
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of North Carolina, Chapel Hill
Subglottic Stenosis (SGS)
Determinants of Rescue Ventilation Requirement in Airway Surgery Under General Anesthesia With THRIVE
The anesthesia and surgical procedures from the time the patient enters the operating room to discharge from the recovery room are identical to those used in conventional airway surgeries performed under general anesthesia with…
- Trial name
- THRIVE (NCT06925282)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital