Clinical trials: Subjective Cognitive Complaints
Subjective Cognitive Decline, Subjective Cognitive Complaint
The Efficacy and Mechanism of Acupuncture Treatment in Patients With Subjective Cognitive Decline
This study evaluates the efficacy and mechanism of acupuncture treatment in patients with subjective cognitive decline. Half of patients will receive acupuncture treatment for 12 weeks, while the other half will receive sham…
- Trial name
- NCT03444896
- Testing
- Acupuncture group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Hospital of Traditional Chinese Medicine
Hippocampal Hyperactivation, Prodromal Alzheimer Disease
Levetiracetam for Persons at Risk for Alzheimer's Disease
The goal of this clinical trial is to investigate whether very small doses of a drug called levetiracetam (LEV) may reduce elevated brain signaling in individuals who are at an increased risk for developing Alzheimer's Disease…
- Trial name
- ALEVIATE-2 (NCT07477431)
- Testing
- Levetiracetam (LEV)
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Sunnybrook Health Sciences Centre
Subjective Cognitive Decline (SCD), Subjective Cognitive Impairment
Testing the Cog-Fun Aging Program for Older Adults With Subjective Cognitive Decline
The goal of this clinical trial is to learn if the Cog-Fun Aging program helps older adults with Subjective Cognitive Decline (SCD) manage memory challenges and improve their daily lives.
- Conditions
- Subjective Cognitive Decline (SCD), Subjective Cognitive Impairment, Subjective Memory Complaints
- Trial name
- NCT06816797
- Testing
- Cog Fun Ageing intervention, Cog-Fun Aging Crossover
- Where
- 3 sites in Israel
- Volunteers
- 27 people
- Sponsor
- Hebrew University of Jerusalem
Subjective Cognitive Impairment
A Study Evaluating the Impact of P-tau217 Blood Biomarker Testing on Early Evaluation and Management of Patients Presenting With Cognitive Complaint
The purpose of the study is to measure the difference in the proportion of participants with prespecified patient management actions between a tested interventional group and a control group.
- Trial name
- NCT07140744
- Testing
- P-tau217, Standard of Care
- Where
- United States
- Volunteers
- 7,000 people
- Sponsor
- Eli Lilly and Company
At-risk Mental States
Prospective Cohort Study of a Population at Risk of Psychotic Transition
In psychiatry, insight is the patient's awareness of his or her disorder or symptom. Lack of insight also seems to be associated with the presence of anxiety-depressive symptoms.
- Trial name
- EPEDIP (NCT06539611)
- Testing
- Observational
- Where
- France
- Volunteers
- 125 people
- Sponsor
- Centre Hospitalier Esquirol
Subjective Cognitive Complaints, Ehlers-Danlos Syndrome
COG+OT Telerehabilitation for Adults With Subjective Cognitive Complaints
This pilot study will evaluate a comprehensive cognitive assessment approach and personalized neurocognitive telerehabilitation intervention for adults with subjective cognitive complaints (SCC).
- Conditions
- Subjective Cognitive Complaints, Ehlers-Danlos Syndrome, Cognitive Dysfunction
- Trial name
- CogSCC (NCT07743229)
- Testing
- COG+OT Telerehabilitation
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Medical University of South Carolina
Healthy Adults With Subjective Memory Complaints
Effects of HX106 on Improvement in Cognitive-Bio-Markers of Memory Function
The objectives of the current study are to evaluate the efficacy and safety of HX106 in healthy adults with subjective memory complaints for improving cognitive and neurobiolgoical markers of memory.
- Trial name
- NCT01956097
- Testing
- HX106 590mg, HX106 1180mg
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Insomnia
Online COgnitive Behavioural Therapy for Sleep and Mental Health for Older Adults With Insomnia and Subjective Cognitive Complaints
The goal of this randomized controlled clinical trial is to assess a novel cognitive-behavioral program for sleep and mental health using a multidomain web platform (eCBTi+) in participants with insomnia and subjective cognitive…
- Trial name
- e-COSMOS (NCT06032377)
- Testing
- cognitive behavioral therapy for sleep, anxiety, and depression, education about healthy nutrition habits and communication in older age
- Where
- 2 sites in Canada
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Subjective Cognitive Complaints, Mindfulness
Mindfulness in Old Adults With Subjective Cognitive Complaints
The study will focus on measuring stress, rumination and cognitive function across three time points in old adults with subjective cognitive complaints via a 4-week short mindfulness intervention, as compare to an active control…
- Trial name
- NCT03195985
- Testing
- Mindfulness-based intervention, Age Well psycho-education
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Cognition, Cancer
Emerging From the Haze™- Measuring the Impact of a Psycho-education Program on Perceived Cognition After Breast Cancer Treatment
At Cedars-Sinai Medical Center, we have developed a novel curriculum for a 6-week psycho-educationally-based, cognitive behavioral program to help patients with subjective cognitive complaints after cancer treatment, titled…
- Trial name
- Haze (NCT02360917)
- Testing
- Emerging from the Haze
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Cedars-Sinai Medical Center
Cognitive Symptom, Pre Senile Dementia
Compensatory Training to Support Brain Healthy Lifestyle Changes in Those at Risk for Alzheimer's Disease
The Researchers are trying to better understand if behavioral interventions can help improve memory compensation and engagement in healthy lifestyle behaviors in those with memory concerns but normal mental status exam.
- Conditions
- Cognitive Symptom, Pre Senile Dementia, Alzheimer Disease
- Trial name
- NCT04118985
- Testing
- Cognitive rehabilitation and health behavior change intervention, Self-implementation
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hypertension
Walking Exercise on Memory, Subjective Cognitive Complaint, and Brain-derived Neurotrophic Factor for Hypertension
The purpose of this study is to determine the effect of 6-month aerobic walking program on memory, subjective cognitive complaints, and brain-derived neurotrophic factor for older hypertensive women.
- Trial name
- NCT04930263
- Testing
- Aerobic exercise, control group
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- National Taiwan University Hospital
Subjective Memory Complaint
Subjective Memory Complaints' Cognitive Intervention
This study will be divided into two parts: development of the mobile medical application for older adults with subjective memory decline and the intervention application.
- Trial name
- SMCCI (NCT05720585)
- Testing
- Intervention of mobile health application
- Volunteers
- 10 people
- Sponsor
- Hongli Chen
Parkinson Disease (PD)
Idiopathic Parkinson's Disease: Interest of an Early Group-Based Cognitive Rehabilitation Program (LIFECOG-PD)
Current pharmacological treatments have not demonstrated significant improvement in cognitive impairment in Parkinson's disease (PD).
- Trial name
- LIFECOG-PD (NCT07813156)
- Testing
- cognitive rehabilitation program
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Clermont-Ferrand
Subjective Memory Loss in Older Persons
Study of the Effects of Cerefolin NAC on Inflammation Blood Markers in Older Individuals With Memory Complaints
The purpose of this six-month research study is to determine if Cerefolin NAC reduces levels of substances in the blood that may be associated with thinking ability and the health of brain cells in subjects with memory concerns…
- Trial name
- NCT00597376
- Testing
- Cerefolin NAC (a medical food)
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Rush University Medical Center
Healthy Adults With Subjective Memory Complaints
Effects of Deer Bone Extract NS on Improvement in Cognitive-Bio-Markers of Cognitive Functions
This study aims to elucidate the effects of deer bone extract NS on cognitive function improvement and its safety in healthy adults aged 40 to 65 years who report decline in subjective cognitive functions using multimodal…
- Trial name
- NCT02379481
- Testing
- NS 550mg, NS 1100mg
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Cognitive Impairment
Vascular Alteration and Evolution of Cognitive Impairment
In the cross sectional study "Adelahyde 1" which took place between 2001 and 2005, the investigators data suggest that vascular alterations may play a role in the setting of subjective memory complaints.
- Trial name
- ADELAHYDE2 (NCT01351961)
- Testing
- blood sampling, brain MRI and TEP cerebral, Assessment of cognitive functions
- Where
- France
- Volunteers
- 131 people
- Sponsor
- Central Hospital, Nancy, France
Subjective Cognitive Decline (SCD), Subjective Cognitive Complaints (SCCs)
The Signature of Alzheimer's Disease in Subjective Cognitive Decline
This study focuses on improving early detection of Alzheimer's disease (AD) in patients with subjective cognitive decline (SCD), a preclinical stage of cognitive impairment, in the context of emerging disease-modifying therapies…
- Conditions
- Subjective Cognitive Decline (SCD), Subjective Cognitive Complaints (SCCs), Subjective Cognitive Impairment, Subjective Cognitive Concerns
- Trial name
- SIGN-AL (NCT07402161)
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- IRCCS Policlinico S. Donato
Subjective Cognitive Complaint, Mild Cognitive Impairment
Validation of the MBI-C Scale in French
This study aims to validate the French version of the Mild Behavioral Impairment-Checklist (MBI-C) scale, hypothetically effective for measuring behavioral symptoms in patients presenting with a subjective cognitive complaint or…
- Conditions
- Subjective Cognitive Complaint, Mild Cognitive Impairment, Neuropsychiatric Symptoms
- Trial name
- MBI-C (NCT06516159)
- Testing
- MBI-C Scale in French
- Where
- 5 sites in France
- Volunteers
- 170 people
- Sponsor
- University Hospital, Toulouse
Active Aging Individuals Aged 65 and Over, Aging
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
The goal of this experimental multicentric intervention study is to validate, in Italian, the dynamic Neurocognitive Adaptation (dNA) Scale, which has already been validated in English, among a healthy elderly population (aged 65…
- Conditions
- Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- NCT07533084
- Where
- 8 sites in Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS