Clinical trials: Sublingual Microcirculation
Vasoplegia Syndrome
Effects of Vitamin C on Shock Duration and Microcirculation in Patients With Vasoplegia Syndrome After Cardiac Surgery
This pilot study intends to observe the effect of intravenous vitamin C on the prognosis and sublingual microcirculation in patients with vasoplegia syndrome after cardiac surgery through a prospective randomized controlled study…
- Trial name
- NCT06723626
- Testing
- Vit C, Standard Preparation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Southeast University, China
Microcirculation Detection in Diabetic Patients
The Predictive Value of Sidestream Dark Field Imaging in Diabetic Nephropathy
Diabetic microangiopathy refers to the pathological changes of arterioles, capillaries and venules in diabetic patients. Due to the impacts including glycol-metabolism disorder, disturbance of lipid metabolism, cytokine…
- Trial name
- NCT04403945
- Testing
- Sidestream dark field(SDF) imagining
- Where
- China
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Third Military Medical University
Shock,, Sepsis
Effects of Sedatives on Sublingual Microcirculation of Patients With Septic Shock
Previous studies have demonstrated that altered microvascular blood flow is an important marker of severe sepsis. Usually, these patients need invasive ventilatory support, frequent use of sedatives and it is unknown if these…
- Trial name
- NCT01618396
- Testing
- Sedation drug (Propofol and Midazolam)
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- Casa de Saúde São José
Complication of Hemodialysis
Microcirculation During Haemodialysis
SDF is validated by measuring changes in microcirculation in sepsis patients with MOF (Boerma studies). SDF is validated by measuring changes in microcirculation in stable chronic hemodialysis patients (NDT 2009 Bemelmans).
- Trial name
- NCT01396980
- Where
- Netherlands
- Volunteers
- 8 people
- Sponsor
- Frisius Medisch Centrum
Surgery, Hypovolemic Shock
Kinetics of the Sublingual Microcirculation During Fluid Bolus
Fluid therapy is one of the cornerstones of the treatment of organ failure. The investigators assume that fluid bolus will increase the delivery of oxygen to the cells and resolve the shock.
- Trial name
- NCT02675725
- Testing
- Measurement of sublingual microcirculation with Cytocam-IDF camera
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Frisius Medisch Centrum
Burn Shock
Evaluation of Sublingual Microcirculation in Burn During Resuscitation
The adequacy of fluid resuscitation will be monitored in burn patients using microcirculation. Microcirculation camera will be placed on the base of the tongue and at different four quadrants.
- Trial name
- NCT05096559
- Testing
- Microcirculation cytocam
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Carotid Artery Plaque, Aortic Aneurysm
Use of Sublingual Microcirculation and FloTrac Monitoring During Major Vascular Surgery and Its Effect on Hospital LOS
the aim of this study is to determine whether an intraoperative optimization protocol using the enhanced flow-based hemodynamic parameters of the FloTrac/Vigileo device in combination with intraoperative measurement of the…
- Conditions
- Carotid Artery Plaque, Aortic Aneurysm, Aneurysm
- Trial name
- NCT04913493
- Testing
- Cytocam-IDF
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Universitair Ziekenhuis Brussel
Healthy
Population Research of Sublingual Microcirculation Data of Healthy Volunteers
This study will enrolled 90 healthy volunteers. The sublingual microcirculation will be examined by sidestreamdark-field videomicroscopy (MicroScan;Microvision Medical, Amsterdam, The Netherlands).
- Trial name
- NCT02359682
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Sepsis
Saline Solution Versus Voluven®: A Controlled Study of Fluid Resuscitation in Severe Sepsis
Fluid resuscitation of severe sepsis may consist of natural or artificial colloids or crystalloids. There is no evidence-based support for one type of fluid over another.
- Trial name
- NCT00799916
- Testing
- Resuscitation (Voluven), Resuscitation (Saline)
- Where
- 3 sites in Argentina
- Volunteers
- 30 people
- Sponsor
- Universidad Nacional de La Plata
Sepsis
Predictive Value of Sublingual Microcirculation and Peripheral Tissue Oxygen Monitoring
Change and predictive Value of Sublingual Microcirculation and Peripheral Tissue Oxygen Monitoring in Sepsis Patients With Successful Fluid Resuscitation
- Trial name
- NCT03859726
- Testing
- NIRS, Sublingual microcirculation
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Xiangya Hospital of Central South University
Cardiac Arrest
Microcirculatory Perfusion in Patients With Coma After Out-of-hospital Cardiac Arrest
The hypothesis is: In patients after an out of hospital cardiac arrest, treated with therapeutic hypothermia (33°C) will be found significantly more microcirculatory abnormalities, compared to the same group of patients treated…
- Trial name
- NCT01850485
- Testing
- microcirculation by SDF and NIRS, in 33 and 36 degrees
- Where
- Netherlands
- Volunteers
- 22 people
- Sponsor
- Frisius Medisch Centrum
Severe Sepsis, Septic Shock
The Effect of Ketanserin on the Microcirculation in Sepsis
This study is an evaluation of the effect of ketanserine on sublingual microcirculation in intensive care patients with severe sepsis.
- Trial name
- NCT01329887
- Testing
- ketanserin
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Frisius Medisch Centrum
Microcirculatory Alterations
The Sublingual Microcirculatory Alterations in Patients Undergoing Extracorporeal Flow Conditions
The aim of this study is to observe the perioperative course of sublingual microcirculatory alterations in patients undergoing coronary artery bypass grafting (CABG) using cold blood compared with cristalloid cardioplegia.
- Trial name
- NCT02144298
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Frisius Medisch Centrum
Acute Respiratory Distress Syndrome
Assessment of Microcirculation Alteration With Both Sublingual Microcirculation and Near-infrared Spectroscopy on ARDS
Microcirculatory alterations are frequently observed in critically ill and severe sepsis patients characterized by a decrease in capillary density and an increase in heterogeneity of perfusion.
- Trial name
- NCT05180409
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Severe Sepsis, Septic Shock
Effects on Microcirculation of IgGAM in Severe Septic/Septic Shock Patients.
IgM-enriched immunoglobulins (IgGAM; Pentaglobin ® ) are new therapy for sepsis and septic shock since they support immune system especially in case of " immunoparalysis" .
- Trial name
- NCT02655133
- Testing
- Pentaglobin®, Physiologic solution
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Università Politecnica delle Marche
Continuous Venovenous Hemofiltration
Microcirculation in Continuous Venovenous Hemofiltration Patients on the Intensive Care Unit
In patients where fluid is withdrawn from the bloodstream by Continuous Venovenous Hemofiltration (CVVH), the ultrafiltration rate will be calculated for a zero balance.
- Trial name
- NCT01362088
- Where
- Netherlands
- Volunteers
- 14 people
- Sponsor
- Frisius Medisch Centrum
Critical Illness, Healthy
Assessment of the Repeatability of Sublingual Microcirculation Function Measurements in Healthy Volunteers and Critically Ill Patients
The assessment of microcirculatory function plays a pivotal role in perioperative medicine and intensive care. One promising method for evaluating microcirculatory function is the microscopic analysis of the oral mucosal…
- Trial name
- NCT07397208
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Dehydration
Microcirculation in Dehydrated Older Patients
This proof-of-concept study examines whether 1) sublingual measurement in dehydrated old patients is feasible, 2) frailty and incompliance in old, awake patients affects video-quality, 3) dehydration impacts microcirculation This…
- Trial name
- MicroCirc (NCT04261374)
- Testing
- Measurement of sublingual microcirculation
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Cardiac Disorder
Microcirculation in Cardiac Surgery
The purpose of this study is to determine whether cardiopulmonary bypass affects mesenteric microcirculatory function, using sublingual evaluation, in cardiac surgery.
- Trial name
- MICROCARD (NCT01330745)
- Testing
- sublingual microcirculatory evaluation
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Rouen
Type1diabetes
Sublingual Microcirculation in Children with Compensated T1D Using the SDF Method
The main goal of the study is to describe the sublingual microcirculation of children with type 1 diabetes mellitus (T1D) with stable and satisfactory treatment of the disease and to compare it with previously measured parameters…
- Trial name
- NCT05958264
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- Vlasta Krausová