Clinical trials: Sublingual Microcirculation
Ischemia Reperfusion Injury, Aortic Aneurysm
Microcirculation and Anesthesia in Vascular Surgery
Ischemia/reperfusion injury following aortic cross-clamping for vascular surgery leads to systemic hemodynamic and microcirculatory perturbances. The use of different anesthetic regimens may have an impact on tissue perfusion.
- Conditions
- Ischemia Reperfusion Injury, Aortic Aneurysm, Anesthesia
- Trial name
- NCT03510793
- Testing
- balanced anesthesia, Total intravenous anesthesia
- Volunteers
- 40 people
- Sponsor
- Università Politecnica delle Marche
Shock, Sepsis
Bedside Visual Analysis of Sublingual Microcirculation in Shock Patients
In shock patients, fluid resuscitation, infusion of vasopressors and transfusion are guided on hemodynamic macrovascular parameters.
- Conditions
- Shock, Sepsis, Hemorrhagic Shock
- Trial name
- MICROEYE (NCT03406598)
- Testing
- Patients in shock
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Transthoracic Esophagectomy
Observational Study of Sublingual Microcirculatory Blood Flow Characteristics in Patients Undergoing Transthoracic Esophagectomy
Microcirculatory alterations occur in critically ill patients and those undergoing major surgeries. The severity of perioperative microvascular alterations appear to be related to the severity of organ dysfunction after surgery.
- Trial name
- NCT02263664
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Virginia
Subarachnoid Hemorrhage
Impact of Nimodipine on Sublingual Microcirculation in Patients With Hemorrhage - a Prospective Monocentric Observational Study
Nimodipine can increase Functional Capillary Density (FCD) as a parameter of the sublingual microcirculation in patients with subarachnoid hemorrhage (SAH) compared to patients without nimodipine.
- Trial name
- NCT04311840
- Where
- Czechia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital Hradec Kralove
Sepsis
Comparison of Microcirculation Indexes and Hemodynamic Indexes to Guide Resuscitation in Patients With Septic Shock
Comparison of Microcirculation Indexes and Hemodynamic Indexes to Guide Resuscitation in Patients With Septic Shock
- Trial name
- NCT05118646
- Testing
- sublingual microcirculation,, hemodynamic monitoring
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Xiangya Hospital of Central South University
Sublingual Microcirculation Status
Sublingual Microcirculation Data of Patients With Systemic Diseases
This is an observational clinical study, patients with systemic diseases will be enrolled according to the inclusion and exclusion criteria.
- Trial name
- NCT02516215
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- National Taiwan University Hospital
Healthy
Sublingual Microcirculation in Healthy Children Using the SDF Imaging Method
The main goal of the study is to determine the physiological parameters of sublingual microcirculation in children in different age categories using Sidestream Dark-Field Imaging Method.
- Trial name
- NCT05324228
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vlasta Krausová
Total Fluid Volume Increased
Effect of Fluid Resuscitation and Microcirculation
Although the investigators take many measurements to monitor the fluid state of the patients, it is not known exactly whether the fluid has real effect on the organ perfusion.
- Trial name
- NCT01369524
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Frisius Medisch Centrum
Anemia in Patients Undergoing Gastric Cancer Surgery Under Goal-directed Fluid Therapy, Macro-microcirculation Uncoupling
Anemia on Sublingual Microcirculation in GDFT
The goal of this observational study is to learn about the effects of anemia on sublingual microcirculation in patients undergoing goal-directed fluid therapy (GDFT) during surgery.
- Trial name
- NCT07583927
- Testing
- No intervention
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Fudan University
Microcirculatory Perfusion
Hemodynamic Evaluation and Assessment of DIRECT myocaRdial and Sublingual Capillary Perfusion in Thoracic Surgery Patients on Cardiopulmonary Bypass
After cardiac surgery, some people may experience problems with their circulation or how well the heart pumps. This can occur because the smallest blood vessels in the heart do not function properly.
- Trial name
- DIRECT-HEART (NCT07135700)
- Volunteers
- 30 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pregnancy, Microcirculation
Parturient Microcirculation
This is an observational study comparing microcirculation of pregnant to non-pregnant women. "Microcirculation" means blood flow to the extremely small blood vessels in one's body.
- Trial name
- NCT01491685
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Critical Illness
Sublingual Microcirculation Monitoring in ICU
Prospective observational study designed to implement a daily monitoring of microcirculation and tissue oxygenation in all critically ill patients admitted to the ICU in the period of nine months, in order to assess the…
- Trial name
- MICRODAIMON (NCT02649088)
- Testing
- Microscan, NIRS from Hutchinson
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Università Politecnica delle Marche
Surgery
Perioperative Observation of the Sublingual Microcirculation With SDF
Does sublingual SDF-imaging results correlate with other haemodynamic parameters measured perioperatively and with postoperative morbidity/complications.
- Trial name
- NCT01037803
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Skane
Emergencies
Microcirculation in Prehospital Medicine
Diagnostic and risk stratification are limited in emergencies. The measurement of microcirculation might identify patients with poor perfusion but compensated macrocirculation such as in beginning shock.
- Trial name
- MicroCircPreHo (NCT04265066)
- Testing
- microcirculation
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Microcirculation
Microcirculation of Patients With Kidney Transplant
This study measures the sublingual microcirculation of patients with kidney transplant using MicroScan. The data will be compared with data of health volunteers and end stage renal disease patients on hemodialysis.
- Trial name
- NCT02874781
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Sepsis
Glycocalyx and Microcirculation in Sepsis
The aim of this observative, prospective study with cross-sectional design is to explore possible correlations/associations between microcirculation parameters and sublingual endothelial glycocalyx in sepsis.
- Trial name
- NCT03960307
- Testing
- Microcirculation and Glycocalyx assessment
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Hypertension, Diabetes Mellitus
Population Research of Sublingual Microcirculation Data of Patients With Systemic Diseases
This is an observational clinical study, patients with systemic diseases will be enrolled according to the inclusion and exclusion criteria.
- Trial name
- NCT02940275
- Where
- Taiwan
- Volunteers
- 156 people
- Sponsor
- National Taiwan University Hospital
Microcirculation
Evaluation of Different Priming Solutions Effects on Microcirculation, Oxidative Stress and Morbidity in Cardiovascular Surgery Patients
Single-centre prospective randomized study will be included the patients who undergo elective cardiovascular surgery. Preoperative fluid deficit will be calculated by the formula as starvation period X 4 X weight.
- Trial name
- Acibadem (NCT02501681)
- Testing
- priming solution during cardiovascular surgery
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Frisius Medisch Centrum
Sublingual Microcirculation
Effect Of Dexmedetomidine On Sublingual Microcirculation In Patients Undergoing On Pump CABG Surgery
This study is designed to explore the possible effects of dexmedetomidine infusion on sublingual microcirculation in patients undergoing on-pump coronary artery bypass graft surgery
- Trial name
- NCT02714725
- Testing
- Dexmedetomidine, Propofol infusion
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Sublingual Microcirculation Pattern and Parameter Analysis
Machine Learning-assisted Analysis of Microcirculation Patterns and Parameters
Machine learning has been widely used in clinical medicine in recent years. It can be used for disease classification, disease severity grading, genetic testing, image analysis, adjuvant treatment recommendations, and predicting…
- Trial name
- NCT04957303
- Testing
- sublingual microcirculation video recording
- Where
- Taiwan
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital