Clinical trials: Sublingual Microcirculation
Septic Shock, Sepsis
Effects of Esmolol on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic Shock
This prospective, multicenter, single-arm interventional pilot study aims to evaluate the short-term physiological effects of intravenous esmolol on sublingual microcirculation and vascular-waterfall parameters in adult patients…
- Conditions
- Septic Shock, Sepsis, Critical Illness Sepsis, Severe
- Trial name
- NCT07657754
- Testing
- Esmolol intravenous infusion
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Healthy
Sublingual Microcirculation of Healthy Volunteers by Using the Third Generation Microcirculation Video Microscope
This study will enroll 150 healthy volunteers, and the grouping is as follows: group 20-39 (30 males and 30 females); group 40-59 (30 males and 30 females); and group 60-79 (15 males and 15 females).
- Trial name
- NCT02412839
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Brain Death
Alterations of Conjunctival Microcirculation in Brain Dead Patients
Study hypothesize that ocular microcirculation is reflecting cerebral perfusion. The purpose of this study is to evaluate ocular microcirculation in brain dead patients using side dark field (SDF) videomicroscope and compare it…
- Trial name
- NCT02483273
- Where
- Lithuania
- Volunteers
- 22 people
- Sponsor
- Lithuanian University of Health Sciences
Angina, Microvascular
Evaluation of the Systemic Microcirculation as a Surrogate for Coronary Microcirculation in Women With ANOCA
The primary objective of this project is to validate a multi-modal systemic microvascular phenotyping platform-combining Laser Speckle Contrast Imaging (LSCI) and Sublingual Handheld Videomicroscopy (IDF imaging)-as a…
- Trial name
- NOCAWT (NCT07558018)
- Testing
- Investigation of Systemic Endothelial Microvascular Function
- Volunteers
- 60 people
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Septic Shock, Sepsis
Effects of Dexmedetomidine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic Shock
This prospective, multicenter, single-arm, open-label interventional pilot study aims to evaluate the short-term physiological effects of intravenous dexmedetomidine on sublingual microcirculation and vascular-waterfall…
- Conditions
- Septic Shock, Sepsis, Critical Illness
- Trial name
- DEX-MICRO (NCT07657715)
- Testing
- Dexmedetomidine Intravenous Infusion
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Colorectal Cancer, Inflammatory Bowel Diseases
Sublingual Microcirculation and Postoperative Ileus
The aim of this pilot study is to establish if a correlation between sub-lingual microcirculation measured by Orthogonal polarization spectral (OPS) imaging and symptoms of postoperative ileus exist in patients undergoing…
- Conditions
- Colorectal Cancer, Inflammatory Bowel Diseases, Gastrointestinal Dysfunction
- Trial name
- NCT01828047
- Testing
- orthogonal polarization spectral (OPS) imaging
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Gabriele Baldini, MD, MSc, Assistant Professor
Microcirculation in Pregnancy
Sublingual Microcirculation Change During Pregnancy and Postpartum Period
Sublingual microcirculation change in pregnant women with or without high risk pregnancy factors during pregnancy and postpartum period.
- Trial name
- Cytocam-OBS (NCT03476096)
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Septic Shock, Sepsis
Effects of Anisodamine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic Shock
This prospective, multicenter, single-arm, open-label interventional pilot study aims to evaluate the short-term physiological effects of intravenous anisodamine on sublingual microcirculation and vascular-waterfall parameters in…
- Conditions
- Septic Shock, Sepsis, Critical Illness
- Trial name
- ANISO-MICRO (NCT07657702)
- Testing
- Anisodamine intravenous infusion
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Septic Shock, Microcirculatory Dysfunction
Papaverine and Sublingual Microcirculation in Septic Shock
This is a prospective, multicenter, single-arm, open-label, pilot physiological study designed to evaluate the effects of intravenous papaverine on sublingual microcirculation and the vascular waterfall phenomenon in adult…
- Conditions
- Septic Shock, Microcirculatory Dysfunction, Sublingual Microcirculation, Hemodynamic Instability
- Trial name
- NCT07657741
- Testing
- Papaverine
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College