Clinical trials: Substance Related Problem
Alcohol; Use, Problem
Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking
Alcohol misuse is a prevalent and serious problem with significant harms to society, individuals, and their relationships. Romantic partners have a strong influence on their partner's behavior, uniquely positioning them as a…
- Trial name
- NCT06501677
- Testing
- WBI
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Stanford University
Posttraumatic Stress Symptom, Alcohol Drinking
Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual Assault
The goal of this study is to find the most effective and efficient version of the THRIVE app. The THRIVE app is the first app-based preventative intervention that has been found to reduce alcohol misuse and posttraumatic stress…
- Conditions
- Posttraumatic Stress Symptom, Alcohol Drinking, Alcohol Problem
- Trial name
- NCT06444295
- Testing
- Activity scheduling, Cognitive restructuring, Coaching calls
- Where
- United States
- Volunteers
- 464 people
- Sponsor
- University of Washington
Alcohol Drinking, Binge Drinking
Reducing Blood Pressure in Mid-life Adult Binge Drinkers
This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers.
- Conditions
- Alcohol Drinking, Binge Drinking, Blood Pressure, Alcohol Abstinence
- Trial name
- NCT05522075
- Testing
- Exercise Training, Alcohol Abstinence Intervention
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Illicit Drugs
The Effectiveness of 3D VR Training System for Supporting Volunteers on Adolescents' Illegal Drug Use
The purpose of that study was to apply the 3D virtual reality technology to develop a training program aiming at improving the abilities of problem solving, self-efficacy and teamwork of supervisory volunteers on adolescents'…
- Trial name
- NCT05072431
- Testing
- SVVR training program
- Where
- Taiwan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Mental Health Issue, Substance Use Disorders
Improving Maternal Mental Health & SUD Screening and Treatment
The purpose of the study is to compare a text message-based mental health and substance use screening and referral to a treatment program, called Listening to Women and Pregnant and Postpartum People (LTWP), to standard of care…
- Conditions
- Mental Health Issue, Substance Use Disorders, Postpartum Depression, Postpartum Anxiety
- Trial name
- NCT05764213
- Testing
- Listening to Women & Pregnant and Postpartum People
- Where
- United States
- Volunteers
- 10,469 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Heavy Episodic Drinking, Problem Drinking
Greek Connections Study
The purpose of this study is to evaluate the feasibility and acceptability of an intervention aiming to reduce heavy episodic drinking and negative consequences from alcohol by increasing the availability of and engagement in…
- Conditions
- Heavy Episodic Drinking, Problem Drinking, College Student Drinking
- Trial name
- NCT07839026
- Testing
- Alcohol-free Social Activities Program
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Washington
Binge Drinking, Heavy Drinking
Brief ROC Training Effects on Alcohol Drinking
The goal of the proposed study is to examine whether a single session of training in regulation of craving (ROC-T) affects alcohol drinking.
- Conditions
- Binge Drinking, Heavy Drinking, Young Adult, Heavy Drinker
- Trial name
- NCT03928626
- Testing
- Regulation of craving, Control (NO REGULATION)
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Yale University
Substance Use, Substance Abuse
Family Engagement, Cross-System Linkage to Substance Use Treatment for Juvenile Probationers -- Phase 3
Developed from adapting and combining two evidence-based programs, Project CONNECT (a linkage-to-services program that targets barriers within the probation and substance abuse treatment systems) and TIES (a program that teaches…
- Conditions
- Substance Use, Substance Abuse, Substance Use Disorders, Substance-Related Disorders
- Trial name
- NCT03048552
- Testing
- Family CONNECT
- Volunteers
- 22 people
- Sponsor
- New York State Psychiatric Institute
Alcohol; Use, Problem
DRT Mobile Intervention to Increase Safe Drinking
The current project uses a brief mobile intervention, grounded in Deviance Regulation Theory, to deliver in-the-moment messaging meant to increase responsible drinking among college students.
- Trial name
- NCT05098639
- Testing
- BASICS, Deviance Regulation Theory (DRT)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Alcohol; Use, Problem, Marijuana Usage
Project RAD: A Brief Intervention for Young Adult Alcohol or Marijuana Users
This is a pilot study of the feasibility, acceptability, and effectiveness of a brief, one-session intervention for a diverse sample of 44 young adults who report alcohol binge drinking or marijuana use in the past month.
- Trial name
- NCT03801096
- Testing
- Narrative Based Therapuetic Assessment (NbTa), Health Education Control Condition (HE)
- Volunteers
- 44 people
- Sponsor
- University of Houston
Cannabis Use Disorder, Severe
Cannabis and Processing Emotions Study
The goal of this study is to test a causal neural mechanism of cannabis use-related problem recognition in individuals with severe cannabis use disorder using a non-invasive form of neuromodulation called transcranial magnetic…
- Trial name
- CAPE (NCT06907979)
- Testing
- TMS - Active iTBS, TMS - Active cTBS
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Auburn University
Alcohol Use Disorder
AABM to Decrease Problem Drinking and Impulsivity in Veterans With AUD: A Pilot Study
The proposed study is a pilot prospective, parallel groups, randomized, double blind, sham training-controlled, 9-session (over 3 weeks) clinical trial of AABM in 32 male and female veterans entering treatment for AUD at the VA…
- Trial name
- AABM (NCT02600832)
- Testing
- AABM Training
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Diabetes Mellitus, Chronic Kidney Diseases
The Multi-Ethnic Lifestyle Study
The study design is cross-sectional using a self-completion questionnaire in an English speaking multi-ethic population within Leicester and Leicestershire.
- Conditions
- Diabetes Mellitus, Chronic Kidney Diseases, Cardiovascular Diseases, Obstructive Sleep Apnea
- Trial name
- MELS (NCT04256720)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 9,500 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Alcohol Use Disorder
Pilot Trial to Evaluate PROblem Solving Therapy and APPLE Watch for College Students
The goals of this Pilot Trial are to test the preliminary efficacy of Problom-Solving Therapy (PST)-APPLE Watch in a 2-arm pilot Randomized Control Trial (RCT), vs education only-control to reduce alcohol use disorder symptoms…
- Trial name
- NCT06333288
- Testing
- PST-APPLE Watch group, Education-only control group
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Alcohol Dependence
Pilot Study of Text Message Brief Interventions for Problem Drinkers
This study will provide a pilot test of two different text message interventions for problem drinkers. Participants will be recruited using a general population telephone survey.
- Trial name
- NCT01180829
- Testing
- Personalized feedback text messages, Consciousness raising text messages
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- Centre for Addiction and Mental Health
Mental Health Issue, Substance Use Disorders
IT to Support Integration of Social Determinant of Health Services to Reduce Avoidable Emergency Department Visits
Working through regional Accountable Care Organizations (ACO) the sponsor will establish a 2-year pilot project to demonstrate that early recognition and intervention in the various Social Determinant of Health (SDoH) domains can…
- Trial name
- NCT04125433
- Testing
- Peer Integrated Care Services
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Northern New York Rural Behavioral Health Institute
Alcohol; Use, Problem
Probiotics, Immune Function, and the Brain in Alcohol Consumers
This pilot project is a brief, open-label clinical trial of probiotics as an intervention in heavy drinkers. Heavy drinkers who do not yet show significant signs of liver disease may stand to benefit from probiotics, but no…
- Trial name
- NCT05232682
- Testing
- Seed DS-01 Daily Synbiotic
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Brown University
Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)
This study is being done to see if outcomes for both a premature infant's parents and the infant born prematurely who have spent time in the neonatal intensive care unit (NICU) can be improved through parent cognitive behavioral…
- Conditions
- Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Development, Child, Parent-Child Relations
- Trial name
- PreVNT (NCT03906435)
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Alcohol Abuse, Alcohol Drinking
Decreasing Alcohol Use Through Student Peer Leaders
Problematic alcohol use can lead to worse social and health related consequences for underserved minorities, requiring urgent intervention.
- Conditions
- Alcohol Abuse, Alcohol Drinking, Alcohol Use Disorder, Alcohol Problem
- Trial name
- NCT04579068
- Testing
- Screening and Brief Intervention of Problematic Alcohol Use
- Volunteers
- healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Assault by Handgun Discharge, Violence
Lithium Water in Gun Violence Prevention
The word lithium frequently conjures images of catatonic psychiatric patients and side effects so severe that premature death is commonplace. But naturally occurring lithium is a far cry from pharmaceutical grades.
- Conditions
- Assault by Handgun Discharge, Violence, Homicide, Sexual Assault by Bodily Force
- Trial name
- LWGVP (NCT02213614)
- Testing
- Lithium Water, natural spring water
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- American Society Of Thermalism And Climatology Inc