Clinical trials: Substance Related Problem
Orthopedic Disorder, Nontraumatic Injury
Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use
The investigator aims to conduct an open pilot study (N=6; 5 completers) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Toolkit for Resilient Life beyond Pain and…
- Conditions
- Orthopedic Disorder, Nontraumatic Injury, Substance Use, Upper Extremity Problem
- Trial name
- NCT06366633
- Testing
- Web-TIRELESS
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Jafar Bakhshaie
Alcohol-Related Disorders, Alcohol Drinking
Stepped Interventions for Problem Drinkers
In a randomized controlled trial, patients recruited in general practices and fulfilling criteria for alcohol dependence, alcohol abuse, at-risk drinking or binge drinking will be allocated to three conditions: (1) Stepped Care…
- Trial name
- NCT00391742
- Testing
- Brief intervention
- Volunteers
- 450 people
- Sponsor
- University of Luebeck
Cannabis Use Disorder, Severe
Cannabis and Processing Emotions Study
The goal of this study is to test a causal neural mechanism of cannabis use-related problem recognition in individuals with severe cannabis use disorder using a non-invasive form of neuromodulation called transcranial magnetic…
- Trial name
- CAPE (NCT06907979)
- Testing
- TMS - Active iTBS, TMS - Active cTBS
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Auburn University
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Homeless Youth Study - Stepping Stone 2.0
Housing instability is both a cause and consequence of mental health problems. As such youth experiencing housing instability (e.g., homeless or marginally housed) have higher rates of mental health problems.Because of their…
- Trial name
- NCT03776422
- Testing
- Mobile self-help intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Alcohol; Use, Problem
Brief Alcohol Screening for Community College Students (BASICCS)
The present study focuses on examining the feasibility, acceptability, and preliminary effects of an adapted alcohol intervention for high-risk college students attending community colleges.
- Trial name
- NCT04052386
- Testing
- BASICCS
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hiv, Alcohol Problem
Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA
This study is designed to examine the efficacy of an alcohol-focused brief intervention alone versus the brief intervention plus referral to a transdiagnostic cognitive-behavioral intervention to address unhealthy alcohol use and…
- Trial name
- TALC (NCT04955795)
- Testing
- Alcohol Brief Intervention (BI), Common Elements Treatment Approach (CETA) via Telemedicine
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- University of Alabama at Birmingham
PTSD, Alcohol; Use, Problem
Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma
The U.S. Deaf community - a group of more than one million Americans who communicate using American Sign Language (ASL) - experiences nearly triple the rate of lifetime problem drinking and twice the rate of trauma exposure…
- Trial name
- NCT06278922
- Testing
- Seeking Safety + Signs of Safety toolkit, Treatment as usual
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Massachusetts, Worcester
Substance Abuse Problem, Pregnancy
Prenatal Cocaine, Nasal Oxytocin, and Maternal Psychophysiology
The purpose of this research is to study the effects of nasal oxytocin administration on maternal behaviors that may be influenced by cocaine use during pregnancy.
- Trial name
- NOX (NCT02872467)
- Testing
- Syntocinon treatment
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Problem Drinking
Changing Impulsivity With Mindful Breathing Therapy to Reduce Problem Drinking
The investigators plan to establish the efficacy of a novel breathing-based mindfulness training (BBMT, a much simplified, easy-to-use version of standard MM) for problem drinking, and test whether impulsivity mediates this…
- Trial name
- BBMT (NCT02527720)
- Testing
- Mindfulness Therapy
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Nicotine Dependence, Cigarettes, Cessation, Tobacco
Reducing Nicotine Addiction in Adolescent Smokers
Adolescents are at risk for tobacco use due to factors such as impulsivity, poor perception, desire to prove themselves, and insufficient neurological development.
- Conditions
- Nicotine Dependence, Cigarettes, Cessation, Tobacco, Cessation, Smoking, Adolescent Problem Behavior
- Trial name
- NCT05477342
- Testing
- Board Game, Tobacco Cesseation Education, Combined İntervention
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Ministry of National Education, Turkey
Problem Drinking, Alcohol Dependence
Screening and Brief Intervention in the ED Among Mexican-origin Young Adults
The aims of this study are to: 1) examine the effectiveness of Screening, Brief Intervention and Referral to Treatment (SBIRT) among Mexican-origin young adults (age 18-25), using a motivational intervention delivered by a Health…
- Trial name
- NCT02056535
- Testing
- Brief Motivational Intervention
- Where
- United States
- Volunteers
- 698 people
- Sponsor
- Public Health Institute, California
Alcoholism, Substance Abuse
Recognition and Early Intervention for Alcohol and Substance Abuse in Adolescence in Adolescent
ASSIST mini-intervention is applied in an electric form in adolescent outpatients to see if it
- Conditions
- Alcoholism, Substance Abuse, Alcohol Dependence, Alcohol-Related Disorders
- Trial name
- REAL-SMART (NCT06262958)
- Testing
- ASSIST, Treatment as usual
- Where
- Finland
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Alcohol; Use, Problem, Posttraumatic Stress Disorder
Understanding and Testing Recovery Processes for PTSD and Alcohol Use Following Sexual Assault
Sexual assault can lead to devastating consequences including the development of chronic conditions including posttraumatic stress disorder (PTSD) and alcohol use disorders (AUD).
- Trial name
- NCT04124380
- Testing
- Imaginal Exposure, Alcohol Skills Training, Supportive Telehealth
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Washington
Substance Abuse, Sleep Disturbances
Exploring Substance Use, Sleep Disturbances and Reward Sensitivity
According to foreign medical studies, substance use is closely related to reward sensitivity and sleep patterns. The purpose of this research is to understand the relationship between these three factors, which will help improve…
- Trial name
- NCT07028346
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Education
- Volunteers
- 154 people
- Sponsor
- Kwai Chung Hospital
Alcohol Dependence
Pilot Study of Text Message Brief Interventions for Problem Drinkers
This study will provide a pilot test of two different text message interventions for problem drinkers. Participants will be recruited using a general population telephone survey.
- Trial name
- NCT01180829
- Testing
- Personalized feedback text messages, Consciousness raising text messages
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- Centre for Addiction and Mental Health
Alcohol Dependence, Alcohol Abuse
Project Motion, A Study of Motivational Interviewing to Reduce Heavy or Problematic Drinking
The purpose of this pilot study is to investigate the critical components of motivational interviewing (MI), a psychotherapeutic intervention, in reducing heavy or problematic drinking.
- Trial name
- NCT00665249
- Testing
- Motivational Interviewing, Spirit-Only Motivational Interviewing, Self-Change
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Northwell Health
Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms
Personalizing Treatment Delivery
Anxiety and anxiety-related disorders frequently co-occur with alcohol use problems resulting in an enormous humanitarian and economic cost to society.
- Conditions
- Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms, Alcohol; Use, Problem; Alcohol Use Disorder
- Trial name
- NCT05821634
- Testing
- Personalized intervention condition: Cognitive behavioral therapy skills, Therapeutic control condition: Cognitive behavioral therapy skills, Tracking control condition: Supportive counseling
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Rutgers, The State University of New Jersey
Alcohol-related Disorders, Alcohol Drinking
Medication and Counseling for Controlled Drinking (Project SMART)
The purpose of this study is to study the effectiveness of medication and specialized psychotherapy in helping gay and bisexual men who do not want to quit drinking learn how to reduce their drinking to healthier levels.
- Conditions
- Alcohol-related Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
- Trial name
- NCT00444418
- Testing
- Naltrexone, Modified Behavioral Self-Control Psychotherapy, Brief Behavioral Compliance Enhancement Therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
HIV/AIDS, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Youth to Text or Telehealth for Engagement in HIV Care
Youth To Text or Telehealth for Engagement in HIV Care (Y2TEC) is a randomized control pilot to assess the feasibility and acceptability of delivering a targeted problem-solving intervention to youth ages 18-29 living with HIV…
- Conditions
- HIV/AIDS, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Depression, Substance Use
- Trial name
- Y2TEC (NCT03681145)
- Testing
- Counselor delivered telehealth intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Alcohol-Related Disorders, Alcohol Use Disorders
Messaging Interventions to Reduce Alcohol Problems Project
The study is designed to develop and test a tailored adaptive text messaging/short message service (SMS) intervention for individuals interested in reducing their alcohol consumption.
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- MIRAP (NCT03695653)
- Testing
- Drink Tracking (MA), Adaptive Tailored (TA), Tailored (TO)
- Where
- United States
- Volunteers
- 730 people
- Sponsor
- Partnership to End Addiction