Clinical trials: Substance Related Problem
PTSD, Alcohol; Use, Problem
Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma
The U.S. Deaf community - a group of more than one million Americans who communicate using American Sign Language (ASL) - experiences nearly triple the rate of lifetime problem drinking and twice the rate of trauma exposure…
- Trial name
- NCT06278922
- Testing
- Seeking Safety + Signs of Safety toolkit, Treatment as usual
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Massachusetts, Worcester
Juvenile Justice Involvement, Drug Abuse
Prevention Program for Problem Behaviors in Girls in Foster Care
This study will determine the efficacy of a parent-involved intervention in preventing problem behavior in middle school girls who are currently in foster care.
- Trial name
- NCT00239837
- Testing
- Middle School Success Intervention (MSS)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oregon Social Learning Center
Alcohol Dependence, Alcohol Consumption
ASAP Study - Hospital-Based Brief Intervention for Alcohol Problems
The objective of this project was to test whether screening and brief intervention for unhealthy alcohol use leads to improved alcohol-related outcomes (such as alcohol consumption and linkage to alcohol assistance) and is…
- Trial name
- NCT00183105
- Testing
- Brief Intervention (adaptation of motivational interviewing)
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Boston Medical Center
Stimulant Use Disorder
Smartphone Services for Stimulant Use Disorder
This study is testing two approaches to treating Stimulant Use Disorder, or problems with cocaine, crack, methamphetamine, etc. Stimulant Use Disorder is a national epidemic in the U.S.
- Trial name
- NCT07092059
- Testing
- Smartphone digital therapeutic system
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- DynamiCare Health
Mental Health Issue, HIV
Single Session Narrative Therapy Study
This pilot research study will provide timely access to behavioral health services through the provision of a single-session narrative therapy intervention.
- Conditions
- Mental Health Issue, HIV, Substance Use
- Trial name
- NCT06479980
- Testing
- Single Session Narrative Therapy
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Washington
Alcohol Abuse, Alcohol-dependence
Treatment Settings for Those With an Alcohol Problem
A prior study in a tightly controlled clinical research environment found individuals with an alcohol use disorder (AUD) benefited more from inpatient (IP) than outpatient (OP) care, if they presented with high alcohol…
- Trial name
- NCT02986776
- Testing
- Inpatient Care, Outpatient Care
- Volunteers
- 176 people
- Sponsor
- State University of New York at Buffalo
HIV Infections
Integrated Treatment of Marijuana Abuse for HIV+ Youth
This is an exploratory study that will adapt and test a combined cognitive behavioral treatment and contingency management intervention for alcohol and/or marijuana abuse for use in HIV-infected adolescents.
- Trial name
- NCT00683488
- Testing
- Focus Group, First Intervention Trial, Intervention Trial 2
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- University of North Carolina, Chapel Hill
Alcohol; Use, Problem, Posttraumatic Stress Disorder
Understanding and Testing Recovery Processes for PTSD and Alcohol Use Following Sexual Assault
Sexual assault can lead to devastating consequences including the development of chronic conditions including posttraumatic stress disorder (PTSD) and alcohol use disorders (AUD).
- Trial name
- NCT04124380
- Testing
- Imaginal Exposure, Alcohol Skills Training, Supportive Telehealth
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Washington
Gambling
Brief Therapies for Problem Gambling Substance Abusers
This project evaluates the efficacy of brief interventions for individuals seeking treatment for substance use disorders who also have gambling problems.
- Trial name
- NCT00685048
- Testing
- 10 minutes of psycho-education, 10 minutes of brief advice, four 50-minute individual therapy sessions of MET & CBT
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- UConn Health
Substance Related Problem
A Media Parenting Prevention Intervention
Entertainment media commonly depict SU, and youth exposure to media SU is linked to youth initiation and progression of SU behavior.
- Trial name
- NCT05332275
- Testing
- Intervention Arm - T.E.C.H. Parenting, Control Arm - General Positive Parenting
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcohol Problem
An Internet Intervention for Alcohol Problems With or Without Assistance From a Health Educator
The purpose of this study is to determine whether an internet intervention for alcohol problems is more effective when delivered with assistance from a health care educator via e-mail during the first two weeks after…
- Trial name
- NCT03601793
- Testing
- Alcohol Help Center, Assistance from a health educator
- Where
- Canada
- Volunteers
- 236 people
- Sponsor
- Centre for Addiction and Mental Health
Mental Health Issue, Substance Use Disorders
Comparing the Effect of Adding a Remote Self-reporting Tool for Distress and Fit-for-purpose Mental Health & Addictions Service to Usual Case Management on Dropout Rates in a Vocational Training Program
Youth unemployment is a chronic problem in most societies. Some young adults are neither in employment, education or training (NEET), and are at high risk of chronic unemployment, social disengagement and poor quality of life.
- Conditions
- Mental Health Issue, Substance Use Disorders, Distress, Emotional
- Trial name
- TeachMeToBuild (NCT05626374)
- Testing
- Basic Case Management, Basic Case Management plus Distress Tool, Basic Case Management plus rapid mental health & addictions healthcare access
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Royal Victoria Hospital, Canada
Alcohol Misuse, Alcohol Use Disorder
Exploration of Acceptability of Alcohol Interventions
This is a mixed-methods study consisting of a qualitative assessment the acceptability of psychosocial interventions, delivered by clinical staff.
- Conditions
- Alcohol Misuse, Alcohol Use Disorder, Behaviour Change, Health Behaviour
- Trial name
- NCT07580378
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- East Lancashire Hospitals NHS Trust
Substance Use, Child Maltreatment
Concurrent Treatment of Substance Abuse and Child Maltreatment
The co-occurrence of child maltreatment and parental substance-use problems is a major public health problem with serious consequences for children, parents, families, and the community at large.
- Trial name
- NCT02774525
- Testing
- Reinforcement for drug & alcohol abstinence, Parenting intervention, Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of South Carolina
Substance Abuse Problem
Identification of New Serum Markers for Detection of Abuse With Erythropoietin
Epo increases red blood cell production and hence the amount of oxygen that can be transported around the body. It is shown that prolonged use of synthetic Epo (rHuEpo) leads to an increase in the period of time a given physical…
- Trial name
- NCT01320449
- Testing
- recombinant human erythropoietin, Training
- Where
- 2 sites in Denmark
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Alcohol Problem, Chronic Pain
PFI for Pain-Related Anxiety Among Hazardous Drinkers With Chronic Pain
There is a pressing public health need to develop novel interventions that aim to reduce alcohol consumption and concurrent alcohol among hazardous drinkers with comorbid chronic pain.
- Conditions
- Alcohol Problem, Chronic Pain, Alcohol Abuse
- Trial name
- NCT05036499
- Testing
- Personalized Feedback Intervention
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- University of Houston
Substance Abuse Problem
Gender-Responsive Treatment for Women Offenders - 1
The purpose of this study is to determine whether substance abuse treatment designed specifically for drug-dependent women offenders provides better outcomes than standard drug court treatment (mixed-gender programs).
- Trial name
- NCT00249613
- Testing
- Women-Only
- Where
- United States
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Alcoholism
An Internet-based Intervention for Problem Drinking
The main aim of this randomized controlled trial is to evaluate the efficacy of an Internet-delivered self-help intervention for problem drinkers in the general population.
- Trial name
- NCT00367575
- Testing
- Internet personalized alcohol feedback (PAF)
- Where
- 3 sites in United States, Canada
- Volunteers
- 359 people
- Sponsor
- Centre for Addiction and Mental Health
Opioid-use Disorder, Addiction
Competitive Revision for CLARO: Collaboration Leading to Addiction Treatment and Recovery From Other Stresses
The purpose of this study is to develop and then test an enhanced version of the parent study's collaborative care intervention for co-occurring disorders (CC-COD) to reduce the risk of suicide and overdose among individuals with…
- Conditions
- Opioid-use Disorder, Addiction, Depression, Post Traumatic Stress Disorder
- Trial name
- NCT04634279
- Testing
- Collaborative care Plus
- Where
- 12 sites in United States
- Volunteers
- 68 people
- Sponsor
- RAND
Alcohol-Related Disorders, Alcohol Use Disorders
Messaging Interventions to Reduce Alcohol Problems Project
The study is designed to develop and test a tailored adaptive text messaging/short message service (SMS) intervention for individuals interested in reducing their alcohol consumption.
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- MIRAP (NCT03695653)
- Testing
- Drink Tracking (MA), Adaptive Tailored (TA), Tailored (TO)
- Where
- United States
- Volunteers
- 730 people
- Sponsor
- Partnership to End Addiction