Clinical trials: Substance Related Problem
Alcohol Problem
Game-Based Intervention to Reduce Alcohol Use Among Youth
This is a randomized controlled trial to learn if the Singularities, a game-based intervention, works to reduce alcohol-related harms among youth.
- Trial name
- NCT07463118
- Testing
- Food4Thought, Singularities
- Where
- United States
- Volunteers
- 1,992 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Alcohol Use, Underage, Alcohol Problem Drinking
Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change
This study will be the first to explore mindfulness as a prevention intervention among transition age youth and those with previous involvement in the juvenile or criminal justice system with substance use problems and history of…
- Conditions
- Alcohol Use, Underage, Alcohol Problem Drinking, Substance Use
- Trial name
- NCT04160754
- Testing
- Mindfulness Based Relapse Prevention, Control (CTL)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Attention Deficit Hyperactivity Disorder, Alcohol-Related Disorders
Helping College Students With ADHD Lead Healthier Lifestyles
There are currently no published randomized controlled studies examining psychosocial interventions for college students with ADHD, and none specifically targeting AUDs in this population at any age, despite the clear indication…
- Conditions
- Attention Deficit Hyperactivity Disorder, Alcohol-Related Disorders, Substance-Related Disorders
- Trial name
- NCT02829970
- Testing
- SUCCEEDS Program, Living a Healthy College Lifestyle
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- University of Maryland, College Park
Alcohol Abuse
E-Health Coping Skills Training for Women Whose Partner Has a Drinking Problem
This study evaluates web-based interventions to help women cope with the stress arising from living with a problem-drinking partner
- Trial name
- NCT02984241
- Testing
- eHealth Coping Skills Training, eHealth Usual Web Care, Coach Support
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- State University of New York at Buffalo
Alcohol; Use, Problem
Alcohol & Mobile Phone Study to Reduce High-risk Alcohol Use and Consequences
The proposed study will develop a smartphone/mobile app intervention that incorporates ecological momentary assessment (i.e., two brief surveys per day) and daily intervention messaging (2 messages per day) for three weeks to…
- Trial name
- AMPS (NCT04213846)
- Testing
- Experimental: Mobile Alcohol Expectancy Intervention
- Where
- United States
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- University of Washington
Neurosciences, Substance-Related Disorders
Neural Mechanisms of Cannabinoid-impaired Decision-Making in Emerging Adults
Emerging adults are a particularly vulnerable group for experiencing the immediate and potentially lifelong negative impacts of habitual cannabis use, and trends suggest that cannabis use disorder (CUD) will soon escalate in this…
- Conditions
- Neurosciences, Substance-Related Disorders, Behavior Problem
- Trial name
- NCT03944954
- Testing
- Marinol 10Mg Capsule TMS Real
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Michael J. Wesley, PhD
Substance Abuse Problem, Pregnancy
Prenatal Cocaine, Nasal Oxytocin, and Maternal Psychophysiology
The purpose of this research is to study the effects of nasal oxytocin administration on maternal behaviors that may be influenced by cocaine use during pregnancy.
- Trial name
- NOX (NCT02872467)
- Testing
- Syntocinon treatment
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Problem Drinking, Alcohol Dependence
Screening and Brief Intervention in the ED Among Mexican-origin Young Adults
The aims of this study are to: 1) examine the effectiveness of Screening, Brief Intervention and Referral to Treatment (SBIRT) among Mexican-origin young adults (age 18-25), using a motivational intervention delivered by a Health…
- Trial name
- NCT02056535
- Testing
- Brief Motivational Intervention
- Where
- United States
- Volunteers
- 698 people
- Sponsor
- Public Health Institute, California
Orthopedic Disorder, Nontraumatic Injury
Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use
The investigator aims to conduct an open pilot study (N=6; 5 completers) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Toolkit for Resilient Life beyond Pain and…
- Conditions
- Orthopedic Disorder, Nontraumatic Injury, Substance Use, Upper Extremity Problem
- Trial name
- NCT06366633
- Testing
- Web-TIRELESS
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Jafar Bakhshaie
Substance Use, Conduct Disorder
A Family Intervention for Adolescent Problem Behavior (AKA Project Alliance 2)
The goal of this project is to empirically refine and improve a comprehensive family-centered prevention strategy for reducing and preventing adolescent substance use and other problem behaviors.
- Conditions
- Substance Use, Conduct Disorder, Depression, Anxiety
- Trial name
- PAL-2 (NCT01490307)
- Testing
- Family Check-Up
- Where
- United States
- Volunteers
- 593 people
- Sponsor
- University of Oregon
Opioid-use Disorder, Addiction
Collaboration Leading to Addiction Treatment and Recovery From Other Stresses
Collaboration Leading to Addiction Treatment and Recovery from Other Stresses (CLARO) is a five-year project that tests whether delivering care using a collaborative model helps patients with both opioid use disorders and mental…
- Conditions
- Opioid-use Disorder, Addiction, Depression, Post-traumatic Stress Disorder
- Trial name
- CLARO (NCT04559893)
- Testing
- Collaborative Care
- Where
- 16 sites in United States
- Volunteers
- 729 people
- Sponsor
- RAND
HIV/AIDS, Mental Health Issue
HIV + Service Delivery and Telemedicine Through Effective PROs
This study will examine the impact of using a multicomponent intervention (patient reported outcomes, training, and telemedicine) to assist with the management of Mental Health (MH) and Substance Use Disorders (SUD) among people…
- Conditions
- HIV/AIDS, Mental Health Issue, Substance Use Disorders
- Trial name
- HIV+STEP (NCT04489667)
- Testing
- +STEP Implementation
- Sponsor
- University of Alabama at Birmingham
Alcohol Dependence
Helping Problem Drinkers on the Internet
The main aim of this study is to compare the impact of a minimal and a full Internet-based self-help intervention for problem drinkers in the general population.
- Trial name
- NCT01114919
- Testing
- Check Your Drinking (CYD), Alcohol Help Centre (AHC)
- Where
- Canada
- Volunteers
- 246 people
- Sponsor
- Centre for Addiction and Mental Health
Substance Use Disorders, Criminal Behavior
Improving Outcomes in Social Services Through Routine Outcome Monitoring and Systematic Client Feedback
In this project the investigators want to test whether a new method FIT (Feedback informed treatment) can improve the interventions people receive through social services.
- Conditions
- Substance Use Disorders, Criminal Behavior, Domestic Violence, Social Care
- Trial name
- NCT07303608
- Testing
- Feedback informed treatment (FIT), Treatment as usual (TAU)
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska Institutet
Problem Drinking
Changing Impulsivity With Mindful Breathing Therapy to Reduce Problem Drinking
The investigators plan to establish the efficacy of a novel breathing-based mindfulness training (BBMT, a much simplified, easy-to-use version of standard MM) for problem drinking, and test whether impulsivity mediates this…
- Trial name
- BBMT (NCT02527720)
- Testing
- Mindfulness Therapy
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Alcohol-related Disorders, Alcohol Drinking
Medication and Counseling for Controlled Drinking (Project SMART)
The purpose of this study is to study the effectiveness of medication and specialized psychotherapy in helping gay and bisexual men who do not want to quit drinking learn how to reduce their drinking to healthier levels.
- Conditions
- Alcohol-related Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
- Trial name
- NCT00444418
- Testing
- Naltrexone, Modified Behavioral Self-Control Psychotherapy, Brief Behavioral Compliance Enhancement Therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Behavior, Addictive, Adolescent - Emotional Problem
"Juego de LLaves": Study Protocol of a Universal School-based Drug Use Prevention Program (PSIDUP)
"Juego de Llaves" is a universal school-based drug prevention program for adolescents aged 12-15 years. The outcome evaluation is critical to determine the quality of preventive interventions.
- Conditions
- Behavior, Addictive, Adolescent - Emotional Problem, Alcohol Abuse, Smoking Behaviors
- Trial name
- PSIDUP (NCT05442294)
- Testing
- Juego de Llaves
- Where
- Spain
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Susana Al-Halabí
Drug Addiction
The Cognitive Neural Mechanisms and Neuroregulatory Interventions of Realistic Creative Problem-solving Under the Effects of Drug Addiction
Drug addiction persists as a significant global social concern with a negative impact on social harmony and stability that cannot be ignored.
- Trial name
- NCT06917534
- Testing
- Transcranial direct current stimulation
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yifan Wang
Alcohol Use Disorder (AUD), Pharmacist-Patient Relations
Alcohol Telemedicine Consultation in Primary Care (ATC)
This pragmatic, cluster-randomized trial in adult primary care clinics in a healthcare system with a diverse membership will examine the effectiveness of an innovative, multi-faceted intervention, the Addiction Telemedicine…
- Conditions
- Alcohol Use Disorder (AUD), Pharmacist-Patient Relations, Alcohol Problem
- Trial name
- ATC (NCT05252221)
- Testing
- ATC Intervention
- Where
- 2 sites in United States
- Volunteers
- 41,843 people
- Sponsor
- Kaiser Permanente
Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms
Personalizing Treatment Delivery
Anxiety and anxiety-related disorders frequently co-occur with alcohol use problems resulting in an enormous humanitarian and economic cost to society.
- Conditions
- Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms, Alcohol; Use, Problem; Alcohol Use Disorder
- Trial name
- NCT05821634
- Testing
- Personalized intervention condition: Cognitive behavioral therapy skills, Therapeutic control condition: Cognitive behavioral therapy skills, Tracking control condition: Supportive counseling
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Rutgers, The State University of New Jersey