Clinical trials: Substance-related Disorders
Alcohol Use Disorder
Selective Attention in Alcohol Use Disorder
This study examines the selective attention to emotional- and alcohol- associated cues in alcohol- dependant and healthy participants.
- Trial name
- NCT03816527
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Schizophrenia, Schizoaffective Disorder
Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia
It is hypothesized that the atypical antipsychotic, Seroquel, will cause significant reduction in drug and alcohol cravings in patients with schizophrenia and comorbid cocaine and/methamphetamine dependence compared to the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Substance Abuse, Substance Dependence
- Trial name
- NCT00208143
- Testing
- Quetiapine, Risperidone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Creighton University
Tobacco Dependence
Efficacy and Safety of Bupropion for Treatment of Adolescent Smoking
The purpose of this study is to determine: 1) the short-term clinical efficacy and safety of bupropion for helping adolescent tobacco smokers quit, and 2) The role of withdrawal symptoms in the maintenance of smoking in…
- Trial name
- NCT00248118
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Binge Drinking, Alcohol Drinking
Alcohol Consumption: Norms, Identities, & Motivations
The emergence of new problematic alcohol consumption practices among young people requires new dynamics in prevention strategies.
- Trial name
- ALCONIM (NCT06447350)
- Testing
- Induced hypocrisy, social identity mapping, Motivational modeling
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Substance Use
Online System for Primary Care to Prevent and Address Teen Substance Use
This Quality Improvement (QI) project for physician education will build on an existing platform, CHADIS (Comprehensive Health and Decision Information System; www.CHADIS.com).
- Trial name
- Substance (NCT04689997)
- Testing
- cSBI
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Total Child Health, Inc.
Cannabis Use
Perceptions of Proposed Warnings for Cannabis Edibles Packaging
The purpose of this study is to compare a delayed-effects warning to an expanded warning developed in previous experiments on knowledge, harm perceptions, and willingness to try cannabis edibles.
- Trial name
- NCT07496489
- Testing
- No Warning Control, Delayed Effects Text Only, Delayed Effects Plus Icon
- Where
- United States
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Prenatal Alcohol Exposure
Effects of Prenatal Alcohol Exposure on Emotional and Cognitive Abilities in Adults
Hypothesis: Individuals presenting with prenatal alcohol exposure (PEA) show emotional abilities deficits, and imbalance between the two systems involved in decision-making according to dual-process models, namely an…
- Trial name
- ALTEMO (NCT03793920)
- Testing
- Facial Emotion Test
- Where
- 2 sites in France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Healthy
Computerized Risk Assessment in an Employee Population
This is a study to determine whether a computerized risk assessment and focused patient provider interaction can improve health outcomes in an employee population.
- Trial name
- NCT00153335
- Testing
- patient-provider interaction
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Social Stigma, Substance Use Disorders
Planning a Multi-Level Intervention to Reduce Substance Use Stigma in HIV Prevention and Care
This is a community-engaged research project that aims to identify and pilot test interventions that may reduce substance use stigma among professionals at primary care sites serving patients who might be exposed to HIV or are…
- Conditions
- Social Stigma, Substance Use Disorders, HIV Infections, Physician-Patient Relations
- Trial name
- NCT05925374
- Testing
- Substance use stigma training
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Alcohol Problem
Game-Based Intervention to Reduce Alcohol Use Among Youth
This is a randomized controlled trial to learn if the Singularities, a game-based intervention, works to reduce alcohol-related harms among youth.
- Trial name
- NCT07463118
- Testing
- Food4Thought, Singularities
- Where
- United States
- Volunteers
- 1,992 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Schizophrenia, Substance Abuse
Screening Protocol for Research Participants
The Screening Protocol is a system devised to evaluate potential research participants for National Institute on Drug Abuse/Maryland Psychiatric Research Center (NIDA/MPRC) studies.
- Conditions
- Schizophrenia, Substance Abuse, Cocaine Abuse, Tobacco Use Disorder
- Trial name
- ScreenProt (NCT01010620)
- Testing
- Various Screening psychiatric and medical assessments
- Where
- United States
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Sleep
Cannabis Association With Sleep Study
The purpose of this study is to learn more about cannabis use, sleep, and stress, and whether there is any relationship between the three.
- Trial name
- CaSS (NCT06982950)
- Testing
- Manipulation of Sleep Duration
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cannabis, Alcohol Effect
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
- Conditions
- Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
- Trial name
- THC-ETOH-II (NCT02710097)
- Testing
- Active inhaled cannabis, Active Oral Ethanol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Use Disorder
Sex Differences in the Response to Abstinence From Alcohol.
In laboratory animals, repeated cycles of abstinence from and return to alcohol drinking can lead to changes in alcohol intake. In a study of the effect of abstinence on drinking in humans, the investigators found evidence that…
- Trial name
- SPAR (NCT03827460)
- Testing
- Abstinence from alcohol, Usual drinking, Intravenous Alcohol
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Indiana University
Substance Abuse, Sexual Behavior
Seek, Test, and Retain. Linkages for Black HIV+, Substance-Using MSM
The study will seek and recruit substance-using Black Men who have Sex with Men (MSM) in New York City for Human Immunodeficiency Virus (HIV) testing and will link and retain those who are HIV infected in HIV primary care.
- Trial name
- STAR (NCT01790360)
- Testing
- Patient Navigation (PN) Intervention, Financial Incentives (FI) Intervention
- Where
- United States
- Volunteers
- 1,930 people, healthy volunteers welcome
- Sponsor
- Columbia University
Alcoholic, Marijuana Misuse
Skills and Motivation at the Rhode Island Training School (Project SMART) - 1
This study will focus on treating substance abusing incarcerated teens using individually administered Motivational Interviewing (MI) followed by group Cognitive Behavior Therapy (CBT).
- Trial name
- NCT00227890
- Testing
- MI/CBT, RT/TU
- Where
- 2 sites in United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Smoking, Tobacco Dependence
Using a Teachable Moment Communication Process to Improve Outcomes of Quitline Referrals
This study will compare the effectiveness of two approaches for delivering smoking cessation advice in the primary care setting.
- Trial name
- NCT02764385
- Testing
- Teachable Moment Communication Process, AAC
- Volunteers
- 15,786 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Alcohol Misuse, Drug Misuse
Family and Social Intervention for Young People
Research evidence shows that there is a high prevalence of substance use among young people in the UK. Early onset and high levels of use are associated with a range of negative outcomes, including increased risk of later…
- Trial name
- YSBNT (NCT02399865)
- Testing
- Youth Social Behaviour and Network Therapy
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Marijuana Use, Opioid Use
Reinforcing Effects of Marijuana and Opioids
The primary goals of this study are to examine 1) marijuana modulation of oxycodone self-administration and 2) oxycodone modulation of marijuana self-administration, under controlled conditions and across a range of doses for…
- Trial name
- NCT05485012
- Testing
- Marijuana, Opioid
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Shanna Babalonis, PhD
Alcohol Dependence
Glycine and Oral D-Cycloserine in Alcoholic Patients and Healthy Subjects
Question #1: Will glycine ameliorate cognitive deficits? Hypothesis #1: Based on positive findings conducted with glycine and milacemide, a glycine prodrug, in schizophrenia and dementia, we expect that glycine will ameliorate…
- Trial name
- NCT00635102
- Testing
- D-Cycloserine PO and Glycine IV
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Yale University
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