Clinical trials: Substrate Oxidation
Overweight Adolescents
SubsTRate OxidatioN in Girls
This study will examine race differences in total energy expenditure and respiratory quotient (RQ) during and after exercise, compared to a sedentary control condition, in adolescent girls who are classified as overweight.
- Trial name
- STRONG (NCT04483921)
- Testing
- Acute exercise
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Glucose Levels, Lipid Profile
Effects of Fasted- Versus Fed-exercise on Metabolic Health in Physically Active Adults
The purpose of this study is to investigate whether the sequence meal and exercise (exercise before meal or exercise after meal) affects the postprandial metabolism.
- Conditions
- Glucose Levels, Lipid Profile, Substrate Oxidation, Blood Pressure
- Trial name
- NCT06949709
- Testing
- Fasted-exercise, Fed-exercise
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Healthy Nutrition
Sex Differences in Metabolism Following a High-fat Meal
Long-term consumption (i.e., several weeks to months) of a diet that is high in fat (>35% daily calories from fat) is associated with the development of insulin resistance, a condition that can lead to a diagnosis of type 2…
- Trial name
- HFM (NCT05332301)
- Testing
- High-fat test meal
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kirsten Bell
Hepatic Glycogen
Liver Glycogen Dynamics
The purpose of this study is to investigate the effect of prolonged overnight fasting in the hepatic glycogen stores
- Trial name
- LGD (NCT04510155)
- Testing
- Overnight fasting duration
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Maximal Rate of Fat Oxidation
Dietary Correlates of the Maximal Capacity for Fat Oxidation
There is a large variability in people's ability to burn fat during exercise. It is thought that differences in dietary intake can partly explain this variation, however this has not been comprehensively studied.
- Trial name
- NCT02070055
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Substrate Absorption, Substrate Oxidation
Effect of Lactose, Fructose, Sucrose, Whey Protein, and Soy Protein on Substrate Absorption and Oxidation: a Pilot Study
Does the consumption of various combinations of mono and disaccharides (lactose, sucrose and fructose) and protein isolates (whey or soy) result in altered substrate absorption, substrate oxidation, and glucose regulation? This…
- Conditions
- Substrate Absorption, Substrate Oxidation, Glucose Regulation
- Trial name
- NCT00942513
- Testing
- trt 1, trt 2, trt 3
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- United States Department of Agriculture (USDA)
Energy Expenditure, Substrate Oxidation
Helichrysum Italicum Infusion Ingestion in Humans
The study evaluates the acute effects of Helichrysum italicum on resting energy expenditure and substrate oxidation in humans. The resting energy expenditure and substrate oxidation will be measured by indirect calorimetry at…
- Conditions
- Energy Expenditure, Substrate Oxidation, Blood Pressure
- Trial name
- SMILJ (NCT04818905)
- Testing
- Helichrysum italicum infusion, Hot water
- Where
- Slovenia
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Diet Induced Thermogenesis
Effect of Within-Meal Consumption of Allulose on Diet-induced Thermogenesis
The objective of this study is to investigate the within-meal effects of allulose compared to sucralose and stevia on diet-induced thermogenesis, substrate oxidation, glycemic response, and subjective appetite in healthy normal…
- Trial name
- NCT07231133
- Testing
- Allulose, Stevia, Sucralose
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Hydration and Resting Metabolism
Water Consumption, Hydration and Resting Energy Expenditure
A randomized, cross over study will assess the effects of ingestion of high and low volumes of water on REE over 90 minutes. The high volume of water 500ml and the low volume of water 250ml.
- Trial name
- NCT03258775
- Testing
- water intake
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- George Mason University
Obesity
Sleep Restriction and Energy Expenditure
Each 4-day period will follow the same protocol. Basically, for the entire study, we will prepare all of the subject's food and will require him or her to eat all of the food that we give at the times we tell them to eat.
- Trial name
- NCT01751581
- Testing
- Short Sleep, Habitual sleep
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Healthy
Effects of a Multi-Ingredient Pre-Workout Supplement on Energy Expenditure During Running
The primary purpose of this study was to examine the acute effects of one versus two doses of a multi-ingredient pre-workout supplement on energy expenditure during moderate-intensity treadmill running.
- Trial name
- NCT04352998
- Testing
- One dose pre-workout condition, Two dose pre-workout condition
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northern Illinois University
Physical Fitness, Mitochondrial Function, Bioenergetics
Effects of Acute Exercise in Fasting and Fed States in Individuals With Different Aerobic Fitness Levels
The aim of this study is to investigate the effects of aerobic fitness level, feeding status, and acute exercise on whole-body metabolic fuel utilization and mitochondrial function in peripheral blood mononuclear cells (PBMCs) in…
- Conditions
- Physical Fitness, Mitochondrial Function, Bioenergetics, Mitochondria, Energy Metabolism
- Trial name
- NCT07813403
- Testing
- Acute Moderate-Intensity Cycling Exercise, Ad Libitum Mixed Meal
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy Aging
Effects of Astaxanthin Supplementation on Metabolism, Cognition, and Physical Function in Older Adults
This study evaluated whether astaxanthin supplementation affects the body's ability to use fat for energy, cognitive performance, and physical function in healthy older adults.
- Trial name
- NCT07876193
- Testing
- Astaxanthin Oral Capsule
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of North Alabama
Diet Induced Thermogenesis
Effect of Allulose on Diet-induced Thermogenesis
The objective of this study is to investigate the dose-response effect of allulose on diet-induced thermogenesis, substrate oxidation, glycemic response, and subjective appetite in healthy normal weight adults.
- Trial name
- NCT06515340
- Testing
- Allulose Dose 1, Allulose Dose 2, Allulose Dose 3
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Menopause
Eating Chocolate at the Right Time Benefits the Circadiam Sytem and Metabolic Efficiency.
The purpose of this investigation is to test the hypothesis that in humans, eating a relatively big amount of chocolate at the wrong time (bedtime) may disrupt our circadian system (change the circadian phase), while taking this…
- Trial name
- ONTIME-CHOC (NCT03949803)
- Testing
- Chocolate 100gr
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Healthy Adults
FueL Use During eXercise in Males and Females
This study will investigate whether pre-exercise nutrition influences sex differences in fuel utilization during endurance exercise.
- Trial name
- FLUX (NCT07829237)
- Testing
- Pre-exercise carbohydrate beverage, Pre-exercise protein beverage, Fasted control beverage
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes Prevention, Obesity Prevention
PERFECT Project - Part 2 - Study 2
The objectives are to test the acute effects of different cereals containing pulse ingredients on: 1) aerobic endurance and substrate oxidation during exercise 2) response of blood glucose, insulin and appetite to an aerobic…
- Trial name
- NCT02370927
- Testing
- Control, Pea protein, Pea Starch
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hydration Status, Substrate Metabolism During Exercise
The Effect of Hydration Status on Substrate Oxidation at Rest and During Light and Moderate Exercise
Metabolic flexibility is the ability to properly switch between fat and carbohydrate stores to use for energy under different conditions (rest, feeding, exercise).
- Trial name
- NCT07298863
- Testing
- Part 1 - Exercise Trial, Part 1 - Experimental Trial, Part 2 - Oral Glucose Tolerance Test
- Where
- 2 sites in United States, Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Lipid Metabolism, Substrate Metabolism
Body Composition and Lipid Metabolism at Rest and During Exercise: A Cross-Sectional Analysis.
The ability to upregulate fat oxidation at appropriate times such as during fasting, low to moderate intensity exercise and after a high fat meal, is popularly advocated.
- Conditions
- Lipid Metabolism, Substrate Metabolism, Exercise
- Trial name
- NCT03029364
- Testing
- Study Protocol
- Where
- United Kingdom
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Bath
Overweight, Postmenopausal
Post Exercise Substrate Oxidation, Appetite and Energy Intakes in Overweight/Obese Postmenopausal Women (EScAPE)
High-intensity interval exercise (HIIT), as compared to moderate intensity continuous training (MICT), is a time-efficient strategy to decrease total and abdominal fat mass (FM).
- Trial name
- EScAPE (NCT04364061)
- Testing
- Moderate Intensity Continuous Exercise, High-Intensity Interval Exercise (1), High-Intensity Interval Exercise (2)
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques