Clinical trials: Success
Ulcerative Colitis
Combined Microbiota and Metabolic Signature in Ulcerative Colitis Predicts Anti-Inflammatory Therapy Success
The primary goal of the study is to develop an early (within 4 weeks) combined microbiota/metabolic signature predicting clinical response upon anti-inflammatory treatment in UC patients.
- Trial name
- COMMIT (NCT05702879)
- Testing
- Ozanimod, TNF Inhibitor, Steroids
- Where
- Switzerland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Mechanical Ventilation Complication
Non Invasive Mechanical Ventilation VERSUS Oxygen MASK
Conventional mechanical ventilation is a core feature of intensive care. Weaning and removal of endotracheal tube are crucial processes, which often account for a considerable part of Conventional mechanical ventilation total…
- Trial name
- NCT03259854
- Testing
- non invasive mechanical ventilation in pediatrics, oxygen mask
- Volunteers
- 104 people
- Sponsor
- Assiut University
Vascular Access Complications
Comparison of AccuCath IV Catheter and Conventional IV Catheter in Interventional Radiology
The study will test a hypothesis that the AccuCath™ System will have a higher rate of successful first attempt peripheral IV placement and higher clinician and patient satisfaction compared to Conventional IV Catheters.
- Trial name
- NCT01940354
- Testing
- AccuCath IV Catheter System, Conventional IV Catheter System
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Haemophilia A
A Survey on the Success of Inhibitor Elimination Using Individualized Concentrate Selection and Controlled ITI
This research program is initiated to evaluate and document data on the success of ITI in 300 haemophilia A patients with newly developed or already existing FVIII-inhibitors (also patients who might potentially have failed in…
- Trial name
- NCT02207894
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Haemophilia Centre Rhine Main
Infertility Female, Zonulin
Effect Of The Mediterranean Diet On Zonulin And Infertility
The goal of this clinical trial is to learn if mediterranean diet works to treat infertility in women. It will also learn about the initial and end of study zonulin levels of mediterranean diet and control group.
- Conditions
- Infertility Female, Zonulin, Intestinal Permeability, Mediterranean Diet
- Trial name
- NCT07072936
- Testing
- mediterranean diet
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- SINEM BAYRAM
Paroxysmal Atrial Fibrillation
Compared With 2 Different Ablation Strategies Clinical Outcome for Treating Patients With Paroxysmal Atrial Fibrillation
Atrial fibrillation (AF) is the most serious atrial electrical activity disorders, is also one of the common tachyarrhythmias.Circumferential pulmonary Vein Isolation (CPVI) is considered to be the cornerstone of paroxysmal…
- Trial name
- NCT03190395
- Testing
- CPVI Group, CPVI+LARA Group
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhujiang Hospital
Smoking, Motivational Interviewing
The Effect of Motivational Interviewing Technique on Smoking Urge and Smoking Cessation Success in Teachers
Background: Smoking, which remains one of the biggest public health threats that the world faces and has reached epidemic proportions, continues to cause more than eight million deaths on average per year worldwide.
- Conditions
- Smoking, Motivational Interviewing, School Health, Nursing
- Trial name
- NCT05374707
- Testing
- MOTIVATIONAL INTERVIEWING
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Irritable Bowel Syndrome (IBS), Genome-wide Association Study
GWAS to Identify Predictive Genetic Factors for the Success of Dietary Intervention in the Treatment of IBS Symptoms
This is a GWAS that aims to identify possible single nucleotide polymorphisms (SNPs) that are associated with the response in a combined dietary pattern low in fermentable oligosaccharides, disaccharides, monosaccharides, and…
- Conditions
- Irritable Bowel Syndrome (IBS), Genome-wide Association Study, Single Nucleotide Polymorphisms, Mediterranean Diet
- Trial name
- NCT06912828
- Testing
- Med-LFD intervention
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital
Adult Patients With Spinal Anesthesia
Comparison of Successful Spinal Needle Placement Between Crossed Leg Sitting Position and Traditional Sitting Position
The study aimed to compare successful spinal needle placement between crossed leg sitting position and traditional sitting position in patients underwent urology surgery.
- Trial name
- NCT02766829
- Testing
- Cross leg sitting position, Traditional sitting position
- Where
- Indonesia
- Volunteers
- 211 people
- Sponsor
- Universitas Indonesia
Extubation Success, Extubation Failure
Combined RSBI, TOF, and BIS for Prediction of Extubation Success
This prospective observational study aims to evaluate the predictive value of the combined use of the rapid shallow breathing index, train-of-four ratio, and bispectral index for extubation success after general anesthesia.
- Conditions
- Extubation Success, Extubation Failure, Postoperative Respiratory Complications
- Trial name
- NCT07577453
- Testing
- Combined pre-extubation assessment using RSBI, TOF ratio, and BIS
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
Breastfeeding
Breast Milk and Breastfeeding Education Given in the Antenatal Period
We aimed to examine the influence of breast milk and breastfeeding education given in the ante-natal period on LATCH score and breastfeeding self-efficacy score.
- Trial name
- BSES-SF (NCT04757324)
- Testing
- breastfeeding education
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Uludag University
HIV Infections
Study to Identify and Determine Best Implementation Practices for Injectable Cabotegravir+Rilpivirine in the United States (US)
Chronic human immunodeficiency virus (HIV) infection in adults continues to be characterized by increased development of resistant virus, increased transmission of resistant virus and issues associated with the long-term toxicity…
- Trial name
- NCT04001803
- Testing
- CAB LA+RPV LA
- Where
- 9 sites in United States
- Volunteers
- 115 people
- Sponsor
- ViiV Healthcare
Retained Product of Conception After First Trimester Medical Abortion
Success Rates of Expectant vs. Medical Management for Retained Products After First-Trimester Abortion: Randomized Controlled Trial
This prospective randomized controlled trial evaluates the success of medical versus expectant management for retained products of conception (RPOC) following medical abortion with mifepristone and misoprostol for delayed…
- Trial name
- NCT07534982
- Testing
- medical management with misoprostol
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Yael Yagur
Tooth Decay
Comparing the Clinical Success of Two Different CAD/CAM Full Cuspal Coverage Onlays
This is a single-center, ten-year, randomized controlled, split-mouth clinical trial. A total of 164 adult patients requiring full-cuspal coverage onlays will be enrolled.
- Trial name
- CUSTOM (NCT07519382)
- Testing
- full cuspal covarage onlay
- Where
- Hungary
- Volunteers
- 164 people
- Sponsor
- Semmelweis University
Intubation
First Attempt Intubation Rate With Airtraq vs Macintosh Direct Laryngoscope
In recent decades, numerous videolaryngoscopes have been introduced to facilitate tracheal intubation. However, it remains unclear whether videolaryngoscope will increase the successful tracheal intubation compared with usual…
- Trial name
- FAIRAiM (NCT03887897)
- Testing
- Tracheal Intubation
- Where
- Hong Kong
- Volunteers
- 1,586 people
- Sponsor
- Chinese University of Hong Kong
Degenerative Disc Disease, Spondylolisthesis
Rate of Bony Fusion Using NanoBone® Synthetic Bone Graft Versus Local Autologous Bone Graft.
The objectives of this longitudinal study are to assess and measure fusion status (fused or not fused) and rate of bony fusion using NanoBone® Synthetic Bone Graft in patients requiring one to two level lumbar posterolateral…
- Trial name
- BONE (NCT04615260)
- Testing
- NanoBone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Artoss Inc.
Parenting Intervention, Stress
Resilience Through Interventions for Successful Early Outcomes
Purpose: The purpose of this research is to determine the effects of Attachment and Biobehavioral Catch-up (ABC), an evidence-based parenting program, on stress biomarkers in children.
- Conditions
- Parenting Intervention, Stress, Caregiver Child Relationship, Child Behavior Problem
- Trial name
- RISE (NCT06669624)
- Testing
- Attachment and Biobehavioral Catch-up (ABC), Waitlist with 4-month delay, then ABC
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of North Carolina, Chapel Hill
External Cephalic Version
Success of External Cephalic Version Study
The purpose of this study is to determine the best way to optimize the success of external cephalic version (turning the baby from the outside).
- Trial name
- NCT03106753
- Testing
- Bupivacaine, Terbutaline
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Endodontic Inflammation, Pulp Disease, Dental
Evaluation of Clinical and Radiological Success of Vital Amputation Treatment
Total amputation therapy; is a treatment method aimed at maintaining the vitality of the radicular pulp remaining as a result of complete removal of coronal pulp tissue.
- Trial name
- NCT03883295
- Testing
- Control, NeoMTA Plus
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Cytomegalovirus Retinitis, HIV Infections
A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Have Not Had Success With Ganciclovir
To evaluate the safety and efficacy of foscarnet induction treatment of cytomegalovirus (CMV) retinitis in AIDS patients who have previously suffered severe dose-limiting ganciclovir-related myelosuppression, who are ineligible…
- Trial name
- NCT00002301
- Testing
- Foscarnet sodium
- Where
- United States
- Sponsor
- Astra USA
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