Clinical trials: Success
HIV Infections
Evaluation of Atazanavir Substitution Intervention (EASI) Study
With the advent of highly active antiretroviral therapy (HAART), it was hypothesized that its consistent use could lead to a cure for HIV infection in as little as three years [Perelson, 1997].
- Trial name
- NCT00247845
- Where
- 5 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Malignant Pleural Effusion
Using Thoracic Ultrasound to Predict Pleurodesis Success in Malignant Pleural Effusions: a Pilot Study
The observational pilot study at the Churchill Hospital, funded by Oxford Respiratory Trials Unit, will assess the feasibility and efficacy of thoracic ultrasound (TUS) assessment in patients undergoing talc pleurodesis via…
- Trial name
- NCT02625675
- Testing
- Ultrasound scan
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Oxford
Premature Tooth Exfoliation
Evaluation of the Success Rate of Prefabricated Versus Conventional Band and Loop Space Maintainers in Children With Prematurely Lost First Primary Molars
To assess the clinical efficacy of prefabricated space maintainers compared to conventional ones, focusing on preserving the integrity of each component of bands and loops, avoidance of soft tissue impingement as well as…
- Trial name
- NCT06558812
- Testing
- prefabricated space maintainer, conventional space maintainer
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Venipuncture
Success Rate Comparison of Venipuncture in Children With and Without Near-infrared Light
The purpose of this study is to determine whether the act of venipuncture is more successful on the first attempt using near infrared light compared to a standard puncture on children or newborn whose venous access is considered…
- Trial name
- ALPIVEINE (NCT05831605)
- Testing
- venipuncture with near-infrared light
- Where
- France
- Volunteers
- 163 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Labor Pain, Epidural Analgesia for Labour and Delivery
Early Labor Pre-Marking for Epidural Analgesia: Ultrasound vs Manual Palpation
The goal of this clinical trial is to learn if finding and marking the best spot on the back early in labor helps doctors perform epidural pain relief more successfully in pregnant women.
- Conditions
- Labor Pain, Epidural Analgesia for Labour and Delivery, Neuraxial Ultrasound
- Trial name
- NCT07669441
- Testing
- Preprocedural Spinal Ultrasound, Conventional Landmark Palpation
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Mental Health, Depression
Designing a Mobile App to Support Academic Success for Student Veterans
Compared to civilian students in higher education, student Veterans have high rates of mental health disorders (e.g., Depression: 24% vs 12.1%).
- Conditions
- Mental Health, Depression, Post-Traumatic Stress Disorder, Anxiety
- Trial name
- NCT05344092
- Testing
- VetEd Mobile Application
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Women Diagnosed With Infertility
The Effect of the Mediterranean Diet on Fatty Acids in Biological Fluids of Women Undergoing Infertility Treatment
The aim of this study was to examine the effect of the Mediterranean diet, which is accepted as one of the adequate and balanced nutrition models today, as well as serum and follicular fluid fatty acid profile and implantation…
- Trial name
- NCT06559904
- Testing
- Mediterranean diet
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Trakya University
Differentiated Thyroid Cancer
A New Study to Follow-up Thyroid Cancer Patients Who Participated in a Previous Study, Which Compared the Success of Destruction of the Thyroid Remnant Using Standard Treatment or Thyrogen.
Patients diagnosed with thyroid cancer are commonly treated with surgery to remove their thyroid gland followed by radioiodine ablation to destroy any remaining parts of the thyroid gland that may have been missed during surgery.
- Trial name
- NCT00295763
- Testing
- Thyrogen (thyrotropin alfa for injection)
- Where
- 9 sites in United States, Canada and 3 more
- Volunteers
- 61 people
- Sponsor
- Genzyme, a Sanofi Company
Catheterization, Peripheral, Catheters, Indwelling
Vein Imaging Device on First-Attempt Success in Peripheral Intravenous Catheter Insertion
This study aimed to evaluate the impact of vein visualization device on catheter placement success and catheter-related complications during peripheral IV catheter insertion in pediatric emergency departments.
- Conditions
- Catheterization, Peripheral, Catheters, Indwelling, Catheter Complications, Pain
- Trial name
- Veinimaging (NCT07006038)
- Testing
- Veinlite PEDI2
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people
- Sponsor
- Dokuz Eylul University
Covid19, Obesity
Association Between Body Mass Index and HFNC Therapy Success
Patients over 18 years of age who are admitted to the Intermediate Care Unit of the Clinica del Country and the Clinica la Colina, with symptoms suggestive of severe pneumonia secondary to COVID-19 infection and acute hypoxemic…
- Conditions
- Covid19, Obesity, Overweight, Pneumonia, Viral
- Trial name
- NCT04799132
- Where
- Colombia
- Volunteers
- 303 people
- Sponsor
- Clínica del country
Confidence, Self
Analysis of Student Confidence Levels and Application Success Rates in Simulator Based Dental Anesthesia Education
The present study investigates confidence levels reported among intern dentists who used dental anesthesia simulators, before performing local anesthesia on patients as well as patient reports on intern dentist confidence levels…
- Trial name
- NCT04654819
- Testing
- Dental anesthesia simulator usage
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara University
Intubation; Difficult or Failed
Flexible Tip Bougie Vs Tube with Stylet for Intubation with a Videolaryngoscopy in ICU (VIDEOL-FLEXTIP)
Tracheal intubation in the intensive care unit (ICU) is associated with high incidence of difficult intubation and complications .
- Trial name
- VIFLEXTIPICU (NCT05429112)
- Testing
- Flexible Tip Bougie, Endotracheal Tube with Stylet
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Acute Kidney Injury
PREdiction of succeSSful weanING From Continuous Renal Replacement Theraphy: the Possible Role of Delta C-cistatin
The goal of this observational study is to know if, in patients with acute kidney injury, naive for renal injurie, admitted to different ICUs, the change in plasma concentration of c-cistatin, between initiation and…
- Trial name
- PRESSING (NCT06714214)
- Where
- 3 sites in Italy
- Volunteers
- 152 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Irreversible Pulpitis (Toothache), Dental Caries (Diagnosis)
Evaluation of the Success Rate of Pulpotomy Versus to Root Canal Therapy in Management of Mature First Permanent Molars With Irreversible Pulpitis
The goal of This current study compare the clinical \& radiographic success rate between two different modalities conventional RCT and VPT using Bio-C-Repair as a pulp capping material to treat young patients with mature first…
- Trial name
- NCT07046533
- Testing
- (pulpotomy), root canal treatment
- Volunteers
- 60 people
- Sponsor
- Lamiaa Saeed Ahmed Elshiekh
Varicose Veins, Endovenous Procedures
Longitudinal or Transverse Orientation of Ultrasound Probe in Minimally Invasive Venous Surgery.
Longitudinal ultrasound orientation during central venous cannulation has been suggested by a number of radomised studies to offer superior cannulation rates.
- Conditions
- Varicose Veins, Endovenous Procedures, Venous Access
- Trial name
- NCT04036734
- Testing
- Longitudinal, Transverse
- Where
- Ireland
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
HIV Infections
Evaluation of Simplified Antiretroviral Treatment Strategies in HIV Infected Children Treated by Antiretroviral (ARV) Before One Year of Age
The MONOD trial aim to evaluate the implementation of early antiretroviral treatment strategies in HIV-infected infants and assess the feasibility and efficacy of simplifying the initial proposed regimen after a successful one…
- Trial name
- NCT01127204
- Testing
- AZT-3TC-LPV/r twice a day, ABC-3TC-EFV once a day
- Where
- 4 sites in Burkina Faso, Côte d’Ivoire
- Volunteers
- 161 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Infant, Premature, Intubation, Intratracheal
Fentanyl and Rocuronium for Tracheal Intubation in Newborns
Tracheal intubation is a common and critical procedure in neonatal intensive care units (NICU). Despite its clinical importance, first-attempt success rates remain low (approximately 50%), and adverse events - including oxygen…
- Conditions
- Infant, Premature, Intubation, Intratracheal, Respiratory Distress Syndrome, Newborn, Apnea of Prematurity
- Trial name
- NEORIN (NCT07650552)
- Testing
- Rocuronium Bromide 10 MG/ML, Fentanyl 1 mcg/kg IV, single dose, administered before non-emergent tracheal intubation.
- Where
- Brazil
- Volunteers
- 102 people
- Sponsor
- UEA - Universidade Do Estado Do Amazonas
Efficiency, Spinal Anesthesia
The Efficiency of Preoperative Pericapsular Nerve Group Block Applied With Ultrasound and Success of Spinal Anesthesia
We aimed to investigate the effectiveness of the pericapsular nerve group (PENG) block applied with preoperative ultrasonography (USG) in patients who were operated on under spinal anesthesia due to hip fracture and whether it…
- Conditions
- Efficiency, Spinal Anesthesia, Block
- Trial name
- PENG (NCT06209372)
- Testing
- Group PENG, Group C
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Suleyman Demirel University
Pulpal Anesthesia
Evaluation of the Success Rate of Pulpal Anesthesia in Mandibular First Molar Following Infiltration of 4% Articaine Alone and as Supplemental Injection After Inferior Alveolar Nerve Block
The purpose of this study is to determine the success rate of pulpal anesthesia in mandibular firs molar following infiltration of 4% articaine alone and as supplemental injection after inferior alveolar nerve block(IANB).
- Trial name
- NCT01593930
- Testing
- Lidocaine(IANB), 1 Articaine(Infiltration), 2 Articaine(Infiltration)
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zahedan University of Medical Sciences
Intubation
Effect of Upright Patient Positioning on Intubation Success
Endotracheal intubation is most commonly taught and performed with the patient supine. Recent literature suggests that elevating the patient's head to a more upright position may decrease peri-intubation complications.
- Trial name
- NCT02885298
- Testing
- Upright intubation
- Volunteers
- 232 people
- Sponsor
- Indiana University
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