Clinical trials: Success
Gastroesophageal Reflux Disease, GERD
What is the Predictive Value of the Reflux Impact Scale
Gastric distress is a common phenomenon in our society. Heartburn and regurgitation occur daily in about 7% of the adult population,weekly 14-20% pf the adults and monthly in 34-44% of adults.
- Conditions
- Gastroesophageal Reflux Disease, GERD, Heartburn, Acid Regurgitation
- Trial name
- PREDICT (NCT00536328)
- Volunteers
- 938 people
- Sponsor
- AstraZeneca
Schizophrenia, Psychotic Disorders
A Study of Treatment Success in Changing From Olanzapine to Long-acting Injectable Risperidone (RISPERDAL® CONSTA™)
The purpose of the study is to evaluate the maintained effectiveness of long-acting injectable risperidone (RISPERDAL® CONSTA™) compared with the previous treatment with oral olanzapine in non-acute subjects with schizophrenia or…
- Trial name
- NCT00216632
- Testing
- risperidone
- Volunteers
- 99 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Obesity, Weight Change, Body
Energy Expenditure and Weight Loss Maintenance
Obesity is reaching epidemic proportions and threatens both health and quality of life of people around the world. While many individuals succeed at short term weight loss, weight loss maintenance is the greatest barrier to…
- Conditions
- Obesity, Weight Change, Body, Weight Loss, Physical Activity
- Trial name
- NCT03422380
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Colorado, Denver
Irreversible Pulpitis (Toothache)
Comparative Evaluation of Intraligamentary Injection of Dexamethasone, Diclofenac Sodium, and Chymotrypsin for Enhancing the Success of 4% Articaine Buccal Infiltration in Mandibular Molars With Symptomatic Irreversible Pulpitis
The goal of this clinical trial is to compare anesthetic success rates of intraligamentary dexamethasone, diclofenac sodium, and chymotrypsin administered prior to buccal 4% articaine infiltration in mandibular molars with…
- Trial name
- NCT07506265
- Testing
- Dexamathsone 4mg/ml associated with experimental arm, Diclofenac Sodium (DCS), chymotrypsin
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Fayoum University
Prosthodontics, Dental Adhesives/Restorations Performance
Evaluation of Ceramic Dental Crown Clinical Performance After Conventional Hydrofluoric Acid Etching or Gaseous Plasma Pretreatment
In this randomized, controlled, double-blind clinical trial, we will follow adult participants who receive partial or full dental crowns made of lithium disilicate ceramic (LDC).
- Conditions
- Prosthodontics, Dental Adhesives/Restorations Performance, Crowned Posterior Teeth
- Trial name
- NCT07876167
- Testing
- Hydrofluoric Acid-Etched Lithium Disilicate Ceramic Dental Crowns, Atmospheric-Pressure Plasma-Treated Lithium Disilicate Ceramic Dental Crowns
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University of Ljubljana, Faculty of Medicine
Child, Only, Catheter Infection
Effect Of Open And Closed System Peripheral Catheters Used In Pediatric Services
The study was conducted as a randomized controlled experimental research to examine the effects of open and closed system peripheral catheters on the success of insertion, duration of stay, and development of complications in…
- Conditions
- Child, Only, Catheter Infection, Catheter Complications
- Trial name
- NCT06312215
- Testing
- Closed-system catheter
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Female Infertility, Female Infertility Due to Ovulatory Disorder
Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility
The study will describe the effectiveness of ovarian stimulation in correlation with female infertility causes in a Lebanese population: a comparative study using 5 protocols of ovulation induction (treatment with "A"…
- Conditions
- Female Infertility, Female Infertility Due to Ovulatory Disorder, Premature Ovarian Failure, Polycystic Ovary Syndrome
- Trial name
- CS-EOSP-ICSI (NCT04071574)
- Testing
- Human Chorionic Gonadotropin (hCG), Gonadotropins, GNRH-A Triptorelin
- Where
- Lebanon
- Volunteers
- 200 people
- Sponsor
- Lebanese University
Infertility Unexplained
Modulation of Reproductive Microbiota by Ligilactobacillus Salivarius CECT5713
The objective of the project is to elucidate if the oral administration of Ligilactobacillus salivarius CECT5713 is capable of improving the rates of term pregnancies in couples with infertility problems of unknown cause.
- Trial name
- NCT06290518
- Testing
- Ligilactobacillus salivarius CECT5713
- Where
- 3 sites in Spain
- Volunteers
- 72 people
- Sponsor
- Biosearch S.A.
Breast Cancer
My Surgical Success: A Randomized Controlled Pilot Study of a Pre-surgical Psychological Intervention
The primary purpose of this study is to determine the feasibility and preliminary efficacy of a remote, Internet-based, pre-surgical psychoeducational intervention delivered to patients scheduled for breast cancer surgery…
- Trial name
- NCT03076190
- Testing
- Psychoeducational My Surgical Success Video
- Volunteers
- 131 people
- Sponsor
- Stanford University
Success of Inferior Alveolar Nerve Block, Inferior Alveolar Nerve Block
Warm Versus Conventional 2% Lignocaine for IANB Efficacy
The study compares the anesthetic efficacy of warm versus conventional 2% lignocaine for inferior alveolar nerve block in mandibular molars, evaluating success rates and onset time.
- Trial name
- NCT06806202
- Testing
- conventional 2% lignocaine at room temperature, pre-warmed 2% lignocaine at 42°C
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Endodontic Disease, Endodontic Re-treatment Failure
Guided Versus Conventional Periapical Endodontic Surgery
This study is to compare the clinical and radiographic outcomes after guided periapical endodontic surgery versus conventional endodontic surgery.
- Trial name
- NCT04133181
- Testing
- 3D guide, Mock guide
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
HIV-1 Infection
4 Consecutive Days on Treatment Followed by 3 Days Off Treatment, in HIV Patients
Evaluate after 48 weeks, the capacity of a weekly strategy of 4 consecutive days on treatment followed by 3 days off treatment, in HIV-1 treated patients with undetectable viral load for at least 12 months and continuous…
- Trial name
- ANRS162-4D (NCT02157311)
- Testing
- Four consecutive days on treatment and 3 days off
- Where
- 17 sites in France
- Volunteers
- 100 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Colorectal Cancer Screening
Optimizing Navigation to Successful Colorectal Cancer Screening
Colorectal cancer is the second leading cause of death from cancer in the United States. Two major barriers to successful colorectal cancer screening are appointment keeping and proper bowel preparation.
- Trial name
- NCT02192034
- Testing
- Navigation
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Interscalene Blocks
The Effect of Anthropometric Measurements on Block Success, Performance Time , and Ultrasound Visibility Score.
The primary objective of this study is to determine whether patients' physical characteristics hold predictive value regarding the difficulty or ease of performing an interscalene block.
- Trial name
- NCT07688889
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Amasya University
Left Atrail Appendage Closure: Peri-device Leaks
Multimodality Evaluation of LAA Leaks Arising After Incomplete LAAC: Insights From the LAA-Leak Registry
Closure of peri-device leaks (PDL) after incomplete LAAC have shown early feasibility, however no comparison study of all the leak closure modalities exists.
- Trial name
- NCT05131308
- Testing
- leak closure with either detachable embolization coils, vascular plugs/CSO, or RFA
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Obesity, Vascular Diseases
Technique for Successful Ultrasound-guided Peripheral Vascular Access
Obtaining peripheral vascular access in medical patients is a necessary procedure for many healthcare providers. Peripheral vascular access is traditionally performed using palpation or visual inspection to identify appropriate…
- Trial name
- NCT01975974
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Spinal Anesthesia, Success or Failure of Spinal Anesthesia
The Influence of Body-mass Index on the Outcome of Spinal Anesthesia for Total Knee Replacement Arthroplasty
In these prospective observational study, the investigators are trying to evaluate (1) the influence of body-mass index on spinal anesthetic outcome and (2) the determinants on spinal anesthetic outcome by logistic regression…
- Trial name
- NCT01609517
- Testing
- Spinal anesthesia (heavy bupivacaine)
- Where
- South Korea
- Volunteers
- 209 people
- Sponsor
- Samsung Medical Center
Dental Implantation
Evaluation of Survival and Success Rates of Zirzonia Dental Implants
Survival and success rates of Zirconia dental implants compared with Titanium implants (Two-Piece Zirconia implants)
- Trial name
- NCT05105113
- Testing
- Zirconia dental implant installation surgery
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Pulpitis - Irreversible, Anesthesia, Local
Effect of Preoperative Diclofenac Potassium on Articaine Buccal Infitration Success
The purpose of this study is to assess the effect of preoperative Diclofenac Potassium (50 mg Cataflam) on the anesthetic success of buccal infiltration with 4% articaine with epinephrine 1:200,000 in mandibular molars with…
- Trial name
- NCT03174860
- Testing
- Diclofenac Potassium 50mg Tab
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
HIV Infections
Evaluation of Therapeutic Drug Monitoring of Protease Inhibitors on Virologic Success and Tolerance of Highly Active Antiretroviral Therapy (HAART)
This Cophar2 study is a trial which evaluates repeated early therapeutic drug monitoring, from weeks 2 to 24, after the initiation of HAART including either indinavir/r, lopinavir/r or the new 625 mg formulation of nelfinavir…
- Trial name
- NCT00122590
- Testing
- nelfinavir, lopinavir/r, indinavir
- Where
- France
- Volunteers
- 115 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
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