Clinical trials: Success of Inferior Alveolar Nerve Block
Inferior Alveolar Nerve, Mandibular Nerve Blocks
Use of CBCT to Improve Inferior Alveolar Nerve Block Success
The study looks to compare the success rate of lower jaw anesthesia injection (inferior alveolar nerve) that is guided by pre-treatment 3D dental scan (CBCT) versus standard injection technique.
- Trial name
- NCT05406895
- Testing
- 2% Lidocaine with 1:100,000 epinephrine
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Local Anesthesia
Effect of Lidocaine/Dexamethasone on the Success of IANB
The purpose of this prospective, randomized, double-blind study was to compare the success rate of IAN block injection carried out with two cartridges of 2% lidocaine with 1:80000 epinephrine each combined with 0.2 ml…
- Trial name
- IANB (NCT03531970)
- Testing
- 2% lidocaine with 1:80,000 epinephrine, Dexamethasone
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Anesthesia, Anesthesia; Functional
IANB Success Rate With and Without Panoramic Help
Since it is difficult to achieve anesthesia in lower jaw and the success rate of IANB is low and there are a lot of anatomic variations for the location of inferior alveolar nerve in different races, investigators decided to…
- Trial name
- NCT03786211
- Testing
- IANB by the guide of Panoramic, IANB without the guide of Panoramic
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hormozgan University of Medical Sciences
Local Anesthesia
Effect of Sodium Bicarbonate Buccal Infiltration on the Success of Inferior Alveolar Nerve Block
The purpose of this prospective, randomized, double blind study was to evaluate the effect of a buccal infiltration of sodium bicarbonate on the anesthetic success of the inferior alveolar nerve block (IANB) in patients with…
- Trial name
- NCT02726737
- Testing
- sodium bicarbonate, Lidocaine, sterile distilled water
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Masoud Saatchi
Pulpitis - Irreversible
SCN9A Gene Expression and Inflammatory Cytokines
Voltage-gated sodium channels, especially Nav1.7 encoded by the SCN9A gene, are key regulators of nociceptive transmission. Upregulation of SCN9A has been associated with increased neuronal excitability and heightened pain…
- Trial name
- Gene Expressio (NCT07532200)
- Testing
- Inferior Alveolar Nerve Block
- Where
- India
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Jamia Millia Islamia
Local Anesthesia
Effect of Lidocaine With Magnesium Sulfate on the Success of the Inferior Alveolar Nerve Block
68 healthy patients pulpitis and requiring root canal therapy are selected. . Sampling was done in a simple and non-experimental way from a dental clinic in Isfahan, and then the samples were randomly assigned to one of the two…
- Trial name
- NCT03262857
- Testing
- use of magnesium sulfate with lidocaine in inferior alveolar nerve block
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Success of Inferior Alveolar Nerve Block
Effect of Magnesium Sulphate Added to Mepivacaine Hydrochloride on Inferior Alveolar Nerve Block Success in Patients With Symptomatic Irreversible Pulpitis in Mandibular Molars: A Randomized Clinical Trial.
the study is conducted to assess the effect of adding magnesium sulphate to mepivacaine HCl compared to mepivacaine HCl alone on the success of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis in…
- Trial name
- NCT04561921
- Testing
- Magnesium sulfate, Mepivacaine-Levonordefrin Hydrochloride
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Local Anesthesia
Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis
Buffering of local anesthetics (alkalinization) has been suggested in achieving pain control. The purpose of this prospective, randomized, double-blind study was to evaluate the effect of adding 0.6 mL 8.4% sodium bicarbonate to…
- Trial name
- NCT02226913
- Testing
- 2% lidocaine with 1:80,000 epinephrine, sodium bicarbonate
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Masoud Saatchi
Inferior Alveolar Nerve Block Failure
Effect of Alprazolam on the Success of Inferior Alveolar Nerve (IAN) Block
The purpose of this prospective, randomized, double-blind, placebo-controlled study is to evaluate the effect of preoperative administration of alprazolam on the success of the IAN block for teeth with irreversible pulpitis.
- Trial name
- NCT01546090
- Testing
- Alprazolam
- Where
- 2 sites in Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Symptomatic Irreversible Pulpitis
Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis
The purpose of this study is to evaluate the success of inferior alveolar nerve block, after the local application of Mepivacaine plus Tramadol in patients with symptomatic irreversible pulpitis.
- Trial name
- NCT02110966
- Testing
- Mepivacaine, Mepivacaine plus Tramadol
- Where
- Mexico
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Daniel Chavarría Bolaños
Pulpal Anesthesia
Evaluation of the Success Rate of Pulpal Anesthesia in Mandibular First Molar Following Infiltration of 4% Articaine Alone and as Supplemental Injection After Inferior Alveolar Nerve Block
The purpose of this study is to determine the success rate of pulpal anesthesia in mandibular firs molar following infiltration of 4% articaine alone and as supplemental injection after inferior alveolar nerve block(IANB).
- Trial name
- NCT01593930
- Testing
- Lidocaine(IANB), 1 Articaine(Infiltration), 2 Articaine(Infiltration)
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zahedan University of Medical Sciences
Failed Mechanical Induction
Efficacy of Ketorolac Buccal Infiltration on Success Rate of Inferior Alveolar Nerve Block
The aim of this study was to determine whether combining an intraoral injection of a non steroidal anti-inflammatory drug (Ketorolac), in association with conventional inferior alveolar nerve block, would improve the success rate…
- Trial name
- NCT02536430
- Testing
- Ketorolac Tromethamine
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nahid Mohammadzadeh Akhlaghi
Postoperative Pain
Effect of Pretreatment Dexamethazone on Pain and Success of Nerve Block
A Comparative Evaluation of the effect of pretreatment dexamethasone versus placebo on post-endodontic pain and success of inferior alveolar nerve block in Mandibular molars with symptomatic Irreversible Pulpitis: A Blinded…
- Trial name
- NCT03199482
- Testing
- Dexamethasone Oral Tablet
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Efficacy of Block Injection of an Anti Inflammatory Medicine in Patients With Mandibular Dental Pain
The aim of this study is to determine whether inferior alveolar nerve block of ketorolac and lidocaine would improve the success rate in teeth with symptomatic irreversible Pulpitis.
- Trial name
- IANB (NCT03410212)
- Testing
- Ketorolac Tromethamine
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Symptomatic Irreversible Pulpitis
The Effect of Buccal Infiltration Administration of Clonidine on the Success Rate of Inferior Alveolar Nerve Block
Articaine/epinephrine and lidocaine/epinephrine are the most common routine local anesthetic agents currently used in dentistry.
- Trial name
- NCT04186299
- Testing
- Clonidine, Articaine Hydrochloride + Epinephrine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Failed Mechanical Induction
Efficacy of Two Injection Techniques on Success Rate of Inferior Alveolar Nerve Anesthesia
Forty healthy patients with including criteria who failed to infra alveolar nerve block injection (without lip numbness) have been randomly divided into two groups on a random basis and have received Gow-Gates or another inferior…
- Trial name
- NCT02543619
- Testing
- Injection technique
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Symptomatic Irreversible Pulpitis
Effectiveness of Premedication on the Success Rate of Inferior Alveolar Nerve Block
Purpose: The aim of this prospective, double-blind, randomized controlled trial is to compare the effect of oral premedication of dexamethasone, ketorolac, meloxicam, ibuprofen or placebo on the success of inferior alveolar nerve…
- Trial name
- NCT05097768
- Testing
- Dexamethasone 0.5mg, Ketorolac 10 Mg Oral Tablet, Meloxicam 7.5 mg
- Where
- Saudi Arabia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Alfarabi Colleges
Success of Inferior Alveolar Nerve Block, Inferior Alveolar Nerve Block
Warm Versus Conventional 2% Lignocaine for IANB Efficacy
The study compares the anesthetic efficacy of warm versus conventional 2% lignocaine for inferior alveolar nerve block in mandibular molars, evaluating success rates and onset time.
- Trial name
- NCT06806202
- Testing
- conventional 2% lignocaine at room temperature, pre-warmed 2% lignocaine at 42°C
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Pulpitis - Irreversible
Single Gene Polymorphism and the Success Rate of Inferior Alveolar Nerve Block
The inferior alveolar nerve block (IANB) is one of the most commonly used techniques in dentistry to achieve mandibular anesthesia during endodontic treatment.
- Trial name
- SNP&IANB (NCT07012382)
- Testing
- Inferior Alveolar Nerve Block, Inferior-Alveolar-Nerve-Block
- Where
- India
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Jamia Millia Islamia
Symptomatic Irreversible Pulpitis (SIP)
COMT, MAOA, and SLC6A4 Polymorphisms and Inferior Alveolar Nerve Block Success
The purpose of this study was to evaluate the association between COMT, MAOA, and SLC6A4 genetic polymorphisms and the success of inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis in…
- Trial name
- NCT07697300
- Testing
- Inferior Alveolar Nerve Block with 4% Articaine
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Marmara University